• Keine Ergebnisse gefunden

ADLERCREUTZ, H. (1998):

Epidemiology of phytoestrogens.

Baillieres Clin. Endocrinol. Metab. 12, 605-623

ADLERCREUTZ, H., T. FOTSIS, C. BANNWART, K. WAHALA, G. BRUNOW u. T. HASE (1991a):

Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein.

Clin. Chim. Acta. 199, 263-278

ADLERCREUTZ, H., K. HOCKERSTEDT, C. BANNWART, S. BLOIGU, E. HAMALAINEN, T. FOTSIS u. A. OLLUS (1987):

Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG).

J. Steroid. Biochem. 27, 1135-1144

ADLERCREUTZ, H., H. HONJO, A. HIGASHI, T. FOTSIS, E. HAMALAINEN, T.

HASEGAWA u. H. OKADA (1991b):

Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet.

Am. J. Clin. Nutr. 54, 1093-1100

ADLERCREUTZ, H., J. VAN DER WILDT, J. KINZEL, H. ATTALLA, K. WAHALA, T.

MAKELA, T. HASE u. T. FOTSIS (1995):

Lignan and isoflavonoid conjugates in human urine.

J. Steroid. Biochem. Mol. Biol. 52, 97-103

ADLERCREUTZ, H., T. YAMADA, K. WAHALA u. S. WATANABE (1999):

Maternal and neonatal phytoestrogens in Japanese women during birth.

Am. J. Obstet. Gynecol. 180, 737-743

AHMED, S. A., R. M. GOGAL u. J. E. WALSH (1993):

A new rapid and somple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to 3H thymidine incorporation assay.

J. Immun. Meth. 70, 211-224 ALAM, J. u. J. L. COOK (1990):

Reporter genes: application to the study of mammalian gene transcription.

Anal. Biochem. 188, 245-254

ALLRED, C. D., K. F. ALLRED, Y. H. JU, S. M. VIRANT u. W. G. HELFERICH (2001):

Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner.

Cancer Res. 61, 5045-5050

Literaturverzeichnis

ANDERSON, J. J. u. S. C. GARNER (1998):

Phytoestrogens and bone.

Baillieres Clin. Endocrinol. Metab. 12, 543-557 ANONYM (2002):

Richtlinie 2002/69&70/EG der Kommission vom 26.Juli 2002.

Amtsblatt der Europäischen Gemeinschaften

ARJMANDI, B. H., L. ALEKEL, B. W. HOLLIS, D. AMIN, M. STACEWICZ-SAPUNTZAKIS, P. GUO u. S. C. KUKREJA (1996):

Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis.

J. Nutr. 126, 161-167

ARNOLD, S. F., B. M. COLLINS, M. K. ROBINSON, L. J. GUILLETTE, JR. u. J. A.

MCLACHLAN (1996a):

Differential interaction of natural and synthetic estrogens with extracellular binding proteins in a yeast estrogen screen.

Steroids 61, 642-646

ARNOLD, S. F., D. KLOTZ, B. M. COLLINS, P. M. VONIER, L. J. GUILLETTE u. J. A.

MCLACHLAN (1996b):

Synergistic activation of estrogen receptor with combination of environmental chemicals.

Science 272, 1489-1492 ASHBY, J. (2000):

Validation of in vitro and in vivo methods for assessing endocrine disrupting chemicals.

Toxicol. Pathol. 28, 432-437

Partial and weak estrogenicity of the red wine constituent resveratrol: consideration of its superagonist activity in MCF-7 cells and its suggested cardiovascular protective effects.

J. Appl. Toxicol. 19, 39-45

ATLURU, S. u. D. ATLURU (1991):

Evidence that genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation.

Transplantation 51, 448-450

AXELSON, M., J. SJOVALL, B. E. GUSTAFSSON u. K. D. SETCHELL (1984):

Soya--a dietary source of the non-steroidal oestrogen equol in man and animals.

J. Endocrinol. 102, 49-56

Literaturverzeichnis

BAKER, V. A. , P. A. HEPBURN, S. J. KENNEDY, P. A. JONES, L. J. LEA, J. P. SUMPTER u.

J. ASHBY (1999):

Safety evaluation of phytosterol esters. Part 1. Assessment of estrogenicity using a combination of in vivo and in vitro assays.

Food Chem. Toxicol. 37, 13-22

BALAGUER, P., F. FRANCOIS, F. COMUNALE, H. FENET, A. M. BOUSSIOUX, M. PONS, J.

C. NICOLAS u. C. CASELLAS (1999):

Reporter cell lines to study the estrogenic effects of xenoestrogens.

Sci. Total. Environ. 233, 47-56

BARNES, S., C. GRUBBS, K. D. SETCHELL u. J. CARLSON (1990):

Soybeans inhibit mammary tumors in models of breast cancer.

Prog. Clin. Biol. Res. 347, 239-253

BARNES, S., J. SFAKIANOS, L. COWARD u. M. KIRK (1996):

Soy isoflavonoids and cancer prevention. Underlying biochemical and pharmacological issues.

Adv. Exp. Med. Biol. 401, 87-100

BARRACLOUGH, C. A., P. CAMP, N. WEILAND u. A. AKABORI (1986):

Stimulatory versus inhibitory effects of progesterone on estrogen-induced phasic LH and prolactin secretion correlated with estrogen nuclear and progestin cytosol receptor concentrations in brain and pituitary gland.

Neuroendocrinology 42, 6-14

BAYER, T., T. COLNOT u. W. DEKANT (2001):

Disposition and biotransformation of the estrogenic isoflavone daidzein in rats.

Toxicol. Sci. 62, 205-211

BEHNISCH, P. A., R. ALLEN, J. ANDERSON u. A. BROUWER (2002):

Harmonized qualitiy criteria for chemical and bioassay analyses of PCDDS/ PCDFS in feed and food.

http://www.biodetectionsystems.com/word/behnisch/html

BENNETTS, H. W., E. J. UNDERWOOD u. F. L. SHIER (1946):

A specific breeding problem of sheep on subterranean clover pastures in western Australia.

Aust. Vet. J. 22, 2-12

BINGHAM, S. A., C. ATKINSON, J. LIGGINS, L. BLUCK u. A. COWARD (1998):

Phyto-oestrogens: where are we now?

Br. J. Nutr. 79, 393-406

BITSCH, N., W. KORNER, S. POSTUPKA u. H. BRUNN (2001):

Application of the E-screen assay to test for estrogenically active substances in swine feed.

J. Anim. Physiol. Anim. Nutr. 85, 369-377

Literaturverzeichnis

BLAIR, R. M., H. FANG, W. S. BRANHAM, B. S. HASS, S. L. DIAL, C. L. MOLAND, W.

TONG, L. SHI, R. PERKINS u. D. M. SHEEHAN (2000):

The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands.

Toxicol. Sci. 54, 138-153 BLÜTHGEN, A. (2006):

Umwelt-Futtermittel-Lebensmittelsicherheit

Kontamination im lebensmittelliefernden Agrarökosystem und Übergang in Kuhmilch.

Tierärztl. Umschau 61, 475-480

BOEIRA, L. S., J. H. BRYCE, G. G. STEWART u. B. FLANNIGAN (2000):

The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts.

J. Appl. Microbiol. 88, 388-403 BÖHM, J. (2000):

Fusarientoxine und ihre Bedeutung in der Tierernährung.

Übers. Tierernähr. 28, 95-132

BOLT, H. M. u. G. H. DEGEN (2002):

Comparative assessment of endocrine modulators with estrogenic activity. II. Persistent organochlorine pollutants.

Arch. Toxicol. 76, 187-193

BRANDENBERGER, A. W., M. K. TEE, J. Y. LEE, V. CHAO u. R. B. JAFFE (1997):

Tissue distribution of estrogen receptors alpha (ER-alpha) and beta (ER-beta) mRNA in the midgestational human fetus.

J. Clin. Endocrinol. Metab. 82, 3509-3512 BREINHOLT, V. u. J. C. LARSEN (1998):

Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay.

Chem. Res. Toxicol. 11, 622-629

BREITHOFER, A., K. GRAUMANN, M. S. SCICCHITANO, S. K. KARATHANASIS, T. R.

BUTT u. A. JUNGBAUER (1998):

Regulation of human estrogen receptor by phytoestrogens in yeast and human cells.

J. Steroid. Biochem. Mol. Biol. 67, 421-429

BRZOZOWSKI, A. M., A. C. PIKE, Z. DAUTER, R. E. HUBBARD, T. BONN, O. ENGSTROM, L. OHMAN, G. L. GREENE, J. A. GUSTAFSSON u. M. CARLQUIST (1997):

Molecular basis of agonism and antagonism in the oestrogen receptor.

Nature 389, 753-758

Literaturverzeichnis

CASSIDY, A. (1996):

Physiological effects of phyto-oestrogens in relation to cancer and other human health risks.

Proc. Nutr. Soc. 55, 399-417

CASSIDY, A. u. M. FAUGHNAN (2000):

Phyto-oestrogens through the life cycle.

Proc. Nutr. Soc. 59, 489-496

CHANG, E. C., J. FRASOR, B. KOMM u. B. S. KATZENELLENBOGEN (2006):

Impact of Estrogen Receptor Beta on Gene Networks Regulated by Estrogen Receptor Alpha in Breast Cancer Cells.

Endocrinology, doi:10.1210/en.2006-0563

CHANG, H. C., M. I. CHURCHWELL, K. B. DELCLOS, R. R. NEWBOLD u. D. R. DOERGE (2000):

Mass spectrometric determination of Genistein tissue distribution in diet-exposed Sprague-Dawley rats.

J. Nutr. 130, 1963-1970

CHANG, Y. C. u. M. G. NAIR (1995):

Metabolism of daidzein and genistein by intestinal bacteria.

J. Nat. Prod. 58, 1892-1896

CIMINO, C. O., S. R. SHELNUTT, M. J. RONIS u. T. M. BADGER (1999):

An LC-MS method to determine concentrations of isoflavones and their sulfate and glucuronide conjugates in urine.

Clin. Chim. Acta. 287, 69-82 CLEVENGER, S. (1964):

Flower Pigments.

Sci. Am. 210, 84-92

COLDHAM, N. G., L. C. HOWELLS, A. SANTI, C. MONTESISSA, C. LANGLAIS, L. J. KING, D. D. MACPHERSON u. M. J. SAUER (1999):

Biotransformation of genistein in the rat: elucidation of metabolite structure by product ion mass fragmentology.

J. Steroid. Biochem. Mol. Biol. 70, 169-184 COLDHAM, N. G. u. M. J. SAUER (2000):

Pharmacokinetics of [(14)C]Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health.

Toxicol. Appl. Pharmacol. 164, 206-215 COLDHAM, N. G. u. M. J. SAUER (2001):

Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement.

Food Chem. Toxicol. 39, 1211-1224

Literaturverzeichnis

COLDITZ, G. A. (1993):

Epidemiology of breast cancer. Findings from the nurses' health study.

Cancer 71, 1480-1489

COLLINS, B. M., J. A. MCLACHLAN u. S. F. ARNOLD (1997):

The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast.

Steroids 62, 365-372

COMMITTEE ON TOXICITY OF CHEMICALS IN FOOD, C. P. A. E. (2003):

Phytoestrogens and Health.

The Food Standard Agency London, UK

CONNOLLY, J. M., X. H. LIU u. D. P. ROSE (1997):

Effects of dietary menhaden oil, soy, and a cyclooxygenase inhibitor on human breast cancer cell growth and metastasis in nude mice.

Nutr. Cancer 29, 48-54

COWARD, L., M. KIRK, N. ALBIN u. S. BARNES (1996):

Analysis of plasma isoflavones by reversed-phase HPLC-multiple reaction ion monitoring-mass spectrometry.

Clin. Chim. Acta. 247, 121-142

CRITCHLEY, H. O., R. M. BRENNER, T. A. HENDERSON, K. WILLIAMS, N. R. NAYAK, O.

D. SLAYDEN, M. R. MILLAR u. P. T. SAUNDERS (2001):

Estrogen receptor beta, but not estrogen receptor alpha, is present in the vascular endothelium of the human and nonhuman primate endometrium.

J. Clin. Endocrinol. Metab. 86, 1370-1378

DAY, A. J., M. S. DUPONT, S. RIDLEY, M. RHODES, M. J. RHODES, M. R. MORGAN u. G.

WILLIAMSON (1998):

Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity.

FEBS Lett. 436, 71-75

DE WET, J. R., K. V. WOOD, M. DELUCA, D. R. HELINSKI u. S. SUBRAMANI (1987):

Firefly luciferase gene: structure and expression in mammalian cells.

Mol. Cell. Biol. 7, 725-737

DECHERING, K., C. BOERSMA u. S. MOSSELMAN (2000):

Estrogen receptors alpha and beta: two receptors of a kind?

Curr. Med. Chem. 7, 561-576

DEGEN, G. H. u. H. M. BOLT (2000):

Endocrine disruptors: update on xenoestrogens.

Int. Arch. Occup. Environ. Health 73, 433-441

Literaturverzeichnis

DEGEN, G. H., P. JANNING, J. WITTSIEPE, A. UPMEIER u. H. M. BOLT (2002):

Integration of mechanistic data in the toxicological evaluation of endocrine modulators.

Toxicol. Lett. 127, 225-237

DEVILLERS, N., C. FARMER, A. M. MOUNIER, J. LE DIVIDICH u. A. PRUNIER (2004):

Hormones, IgG and lactose changes around parturition in plasma, and colostrum or saliva of multiparous sows.

Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry.

Drug. Metab. Dispos. 28, 298-307

DOERGE, D. R., M. I. CHURCHWELL, H. C. CHANG, R. R. NEWBOLD u. K. B. DELCLOS (2001):

Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats.

Reprod. Toxicol. 15, 105-110

DRANE, H. M., A. E. WRATHALL, D. S. PATTERSON u. C. N. HEBERT (1981):

Possible estrogenic effects of feeding soyameal to prepubertal gilts.

Br. Vet. J. 137, 283-288 DROCHNER, W. (1990):

Aktuelle Aspekte zur Wirkung von Phytohormonen, myktotoxinen und ausgewählten schädlichen Pflanzeninhaltsstoffen auf die Fruchtbarkeit beim weiblichen Rind.

Übers. Tierernährung 18, 177-169

EISENBRAND, G., B. MUßLER u. G. H. DEGEN (2002):

Kombinationswirkungen hormonartig wirkender Chemikalien.

Arbeitsphysiologie heute 2, 27-39

EISSA, S., A. KHALIFA, A. EL-GHARIB, N. SALAH u. M. K. MOHAMED (1997):

Multivariate analysis of DNA ploidy, p53, c-erbB-2 proteins, EGFR, and steroid hormone receptors for short-term prognosis in breast cancer.

Anticancer Res. 17, 3091-3097

ELDRIGE, A. C. u. W. F. KWOLEK (1983):

Soybean isoflavones: effect of environment and variety on composition.

J. Agric. Food Chem. 31, 394-396

Literaturverzeichnis

ELGHAMRY, M. E., E. GRUNERT u. G. SCHULTZ (1969):

Nachweis von Formononetin und Biochanin A im Gras einer Weide, auf der bei nichttragenden Färsen Euteranbildungen festgestellt wurden.

Biol. Zbl. 88, 769-777

ENGELHARDT, W. V. u. G. BREVES (2000):

Endokrinologie.

In: Physiologie der Haustiere Enke Verlag, Stuttgart, 490 - 496

ENMARK, E., M. PELTO-HUIKKO, K. GRANDIEN, S. LAGERCRANTZ, J. LAGERCRANTZ, G. FRIED, M. NORDENSKJOLD u. J. A. GUSTAFSSON (1997):

Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.

J. Clin. Endocrinol. Metab. 82, 4258-4265 EVANS, R. M. (1988):

The steroid and thyroid hormone receptor superfamily.

Science 240, 889-895

FANG, H., W. TONG, L. M. SHI, R. BLAIR, R. PERKINS, W. BRANHAM, B. S. HASS, Q. XIE, S. L. DIAL, C. L. MOLAND u. D. M. SHEEHAN (2001):

Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Chem. Res. Toxicol. 14, 280-294

FANG, N., S. YU u. T. M. BADGER (2002):

Characterization of isoflavones and their conjugates in female rat urine using LC/MS/MS.

J. Agric. Food Chem. 50, 2700-2707

FARHAT, M. Y., M. C. LAVIGNE u. P. W. RAMWELL (1996):

The vascular protective effects of estrogen.

Faseb. J. 10, 615-624

FARMAKALIDIS, E. u. P. A. MURPHY (1985):

Isolation of 6´-O-Acetylgenistein and 6´-O-Acetyldaidzein from toasted defatted soyflakes.

J. Agric. Food Chem. 33, 385-389

FARNSWORTH, N. R., A. S. BINGEL, G. A. CORDELL, F. A. CRANE u. H. S. FONG (1975):

Potential value of plants as sources of new antifertility agents II.

J. Pharm. Sci. 64, 717-754

FILLIT, H., H. WEINREB, I. CHOLST, V. LUINE, B. MCEWEN, R. AMADOR u. J.

ZABRISKIE (1986):

Observations in a preliminary open trial of estradiol therapy for senile dementia-Alzheimer's type.

Psychoneuroendocrinology 11, 337-345

Literaturverzeichnis

FORTH, W., D. HENSCHLER, W. RUMMEL u. K. STARKE (2001):

Sexualhormone.

In: Allgemeine und spezielle Pharmakologie und Toxikologie Urban und Fischer München und Jena, S. 687-701

FOSTER, W. G., S. CHAN, L. PLATT u. C. L. HUGHES, JR. (2002):

Detection of phytoestrogens in samples of second trimester human amniotic fluid.

Toxicol. Lett. 129, 199-205

FRANCIS, C. M. u. I. D. HUME (1971):

The relationship between lignification and flavonoid production in subterranean clover Aust. J. Biol. Sci. 24, 1-5

FRANKE, A. A. u. L. J. CUSTER (1996):

Daidzein and genistein concentrations in human milk after soy consumption.

Clin. Chem. 42, 955-964

FRANKE, A. A., L. J. CUSTER, C. M. CERNA u. K. NARALA (1995):

Rapid HPLC analysis of dietary phytoestrogens from legumes and from human urine.

Proc. Soc. Exp. Biol. Med. 208, 18-26

FRANKE, A. A., L. J. CUSTER, C. M. CERNA u. K. K. NARALA (1994):

Quantitation of phytoestrogens in legumes by HPLC.

J. Agric. Food Chem. 42, 1905-1913

FRANKE, A. A., L. J. CUSTER u. Y. TANAKA (1998):

Isoflavones in human breast milk and other biological fluids.

Am. J. Clin. Nutr. 68, 1466-1473 FUHRMANN, H. (1992):

Germany in the High Middle Ages, 1050-1200 Cambridge University Press, Cambridge

GAIDO, K. W., D. P. MCDONELL, K. S. KORACH u. S. H. SAFE (1997):

Estrogenic activity of chemical mixtures: Is there synergism? . CITT. 17, 1-7

GALEY, F. D., L. E. MENDEZ, W. E. WHITEHEAD, D. M. HOLSTEGE, K. H. PLUMLEE u. B.

JOHNSON (1993):

Estrogenic activity in forages: diagnostic use of the classical mouse uterine bioassay.

J. Vet. Diagn. Invest. 5, 603-608

GAREIS, M., J. BAUER, J. THIEM, G. PLANK, S. GRABLEY u. B. GEDEK (1990):

Cleavage of zearalenone-glycoside, a "masked" mycotoxin, during digestion in swine.

Zentralbl. Veterinarmed. B. 37, 236-240

Literaturverzeichnis

GARRETT, S. D., H. A. LEE, P. M. FRIAR u. M. R. MORGAN (1999):

Validation of a novel estrogen receptor-based microtitration plate assay for the determination of phytoestrogens in soy-based foods.

J. Agric. Food Chem. 47, 4106-4111

GIUSTI, R. M., K. IWAMOTO u. E. E. HATCH (1995):

Diethylstilbestrol revisited: a review of the long-term health effects.

Ann. Intern. Med. 122, 778-788 GREEN, S. u. P. CHAMBON (1988):

Nuclear receptors enhance our understanding of transcription regulation.

Trends. Genet. 4, 309-314

GREEN, S., P. WALTER, V. KUMAR, A. KRUST, J. M. BORNERT, P. ARGOS u. P.

CHAMBON (1986):

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A.

Nature 320, 134-139

GREENE, G. L., P. GILNA, M. WATERFIELD, A. BAKER, Y. HORT u. J. SHINE (1986):

Sequence and expression of human estrogen receptor complementary DNA.

Science 231, 1150-1154

GRIFFITH, A. P. u. M. W. COLLISON (2001):

Improved methods for the extraction and analysis of isoflavones from soy-containing foods and nutritional supplements by reversed-phase high-performance liquid chromatography and liquid chromatography-mass spectrometry.

J. Chromatogr. A. 913, 397-413 GRONEMEYER, H. (1991):

Transcription activation by estrogen and progesterone receptors.

Annu. Rev. Genet. 25, 89-123 GROSSMAN, C. J. (1984):

Regulation of the immune system by sex steroids.

Endocr. Rev. 5, 435-455

GRUNERT, E. u. A. HOFFMANN (1971):

Klinische Erscheinungen und Fruchtbarkeitsstörungen bei Haustieren nach Aufnahme östrogenhaltiger Futterpflanzen.

Dtsch. tierärztl. Wschr. 78, 49-72

GUST, R., S. BUSCH, R. KEILITZ, K. SCHMIDT u. M. VON RAUCH (2003):

Invesgations [correction investigations] on the influence of halide substituents on the estrogen receptor interaction of 2, 4, 5-tris(4-hydroxyphenyl)imidazoles.

Arch. Pharm., 336, 456-465

Literaturverzeichnis

HAFNER, F., E. HOLLER u. E. VON ANGERER (1996):

Effect of growth factors on estrogen receptor mediated gene expression.

J. Steroid. Biochem. Mol. Biol. 58, 385-393 HALL, J. M. u. D. P. MCDONNELL (1999):

The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens.

Endocrinology 140, 5566-5578

HAWKINS, M. B., J. W. THORNTON, D. CREWS, J. K. SKIPPER, A. DOTTE u. P. THOMAS (2000):

Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts.

Proc. Natl. Acad. Sci. USA 97, 10751-10756

HEINONEN, S., K. WAHALA u. H. ADLERCREUTZ (1999):

Identification of isoflavone metabolites dihydrodaidzein, dihydrogenistein, 6'-OH-O-dma, and cis-4-OH-equol in human urine by gas chromatography-mass spectroscopy using authentic reference compounds.

Anal. Biochem. 274, 211-219

HENDERSON, B. E., A. PAGANINI-HILL u. R. K. ROSS (1988):

Estrogen replacement therapy and protection from acute myocardial infarction.

Am. J. Obstet. Gynecol. 159, 312-317

HENDERSON, B. E., R. K. ROSS, A. PAGANINI-HILL u. T. M. MACK (1986):

Estrogen use and cardiovascular disease.

Am. J. Obstet. Gynecol. 154, 1181-1186 HOCK, B., S. ROTHE u. M. SEIFERT (2000):

Hormone in der Umwelt - die Tests im Überblick.

Nachricht. Chem. 48, 918-924

HOEY, L., I. R. ROWLAND, A. S. LLOYD, D. B. CLARKE u. H. WISEMAN (2004):

Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children.

Br. J. Nutr. 91, 607-616

HOPERT, A. C., A. BEYER, K. FRANK, E. STRUNCK, W. WUNSCHE u. G. VOLLMER (1998):

Characterization of estrogenicity of phytoestrogens in an endometrial-derived experimental model.

Environ. Health Perspect. 106, 581-586

Literaturverzeichnis

HUBBARD, R. E., A. C. PIKE, A. M. BRZOZOWSKI, J. WALTON, T. BONN, J. A.

GUSTAFSSON u. M. CARLQUIST (2000):

Structural insights into the mechanisms of agonism and antagonism in oestrogen receptor isoforms.

Eur. J. Cancer. 36/4, 17-18 HUGHES, C. L., JR. (1988):

Phytochemical mimicry of reproductive hormones and modulation of herbivore fertility by phytoestrogens.

Environ. Health Perspect. 78, 171-174 HUMFREY, C. D. (1998):

Phytoestrogens and human health effects: weighing up the current evidence.

Nat. Toxins 6, 51-59

HUNTER, D. S., L. C. HODGES, P. M. VONIER, R. FUCHS-YOUNG, M. M. GOTTARDIS u. C.

L. WALKER (1999):

Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium.

Cancer Res. 59, 3090-3099

IAVARONE, M., P. LAMPERTICO, C. SELETTI, M. FRANCESCA DONATO, G. RONCHI, E.

DEL NINNO u. M. COLOMBO (2003):

The clinical and pathogenetic significance of estrogen receptor-beta expression in chronic liver diseases and liver carcinoma.

Cancer 98, 529-534

IBARRETA, D., A. DAXENBERGER u. H. H. MEYER (2001):

Possible health impact of phytoestrogens and xenoestrogens in food.

Apmis. 109, 161-184

ISHIKAWA, T., K. TAKANO, J. YASUFUKU-TAKANO, T. FUJITA, T. IGARASHI, M.

MIURA u. K. HATA (2001):

Estrogenic impurities in labware.

Nat. Biotechnol. 19, 812

JENSEN, E. V. u. H. I. JACOBSON (1962):

Basic guides to the mechanism of estrogen action.

Recent Prog. Horm. Res. 18, 387-414 JOBLING, S. (1998):

Review of suggested testing methods for endocrine-disrupting chemicals.

Pure Appl. Chem. 70, 1805-1827

JONAS, A., H. BESSELINK u. A. BROUWER (2002):

Introduction of a linear 2,3,7,8-TCDD curve-fit as means to improve performance characteristics of DR CALUX bioassay.

BioDetection Systems, Forschungsarbeit

Literaturverzeichnis

JU, Y. H., C. D. ALLRED, K. F. ALLRED, K. L. KARKO, D. R. DOERGE u. W. G. HELFERICH (2001):

Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice.

J. Nutr. 131, 2957-2962

KALDAS, R. S. u. C. L. HUGHES, JR. (1989):

Reproductive and general metabolic effects of phytoestrogens in mammals.

Reprod. Toxicol. 3, 81-89 KALLELA, K. (1964):

On the estrogenic effects of red clover fodder on sheep.

Nord. Vet. Med. 16, 731-743

KAMPHUES, J., M. COENEN, E. KIENZLE, J. PALLAUF, O. SIMON u. J. ZENTEK (2004):

Supplemente zu Vorlesungen und Übungen in der Tierernährung.

Verlag M. & H. Schaper, Hannover

KARALJOV, Dzmitry (Dissertation in prep.)

Vorkommen und Wirkungen von estrogn aktiven Substanzen im Futter für Schweine Hannover, Tierärztl. Hochsch. , Diss. in prep.

KARAS, R. H., J. B. HODGIN, M. KWOUN, J. H. KREGE, M. ARONOVITZ, W. MACKEY, J.

A. GUSTAFSSON, K. S. KORACH, O. SMITHIES u. M. E. MENDELSOHN (1999):

Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.

Proc. Natl. Acad. Sci. USA 96, 15133-15136

KELLY, G. E., G. E. JOANNOU, A. Y. REEDER, C. NELSON u. M. A. WARING (1995):

The variable metabolic response to dietary isoflavones in humans.

Proc. Soc. Exp. Biol. Med. 208, 40-43 KELLY, R. W. (1972):

The estrogenic activity of coumestans in ovariectomized ewes.

J. Reprod. Fertil. 28, 159

KHODABANDEHLOU, H., B. HOFFMANN u. J. PALLAUF (1997):

Untersuchungen in Mittelhessen zum Vorkommen von östrogen-wirksamen Inhaltsstoffen im Rinderfutter.

Dtsch. tierärztl. Wschr. 104, 269-340 KING, R. A. u. D. B. BURSILL (1998):

Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans.

Am. J. Clin. Nutr. 67, 867-872

Literaturverzeichnis

KITAOKA, M., H. KADOKAWA, M. SUGANO, K. ICHIKAWA, M. TAKI, S. TAKAISHI, Y.

IIJIMA, S. TSUTSUMI, M. BORIBOON u. T. AKIYAMA (1998):

Prenylflavonoids: a new class of non-steroidal phytoestrogen (Part 1). Isolation of 8-isopentenylnaringenin and an initial study on its structure-activity relationship.

Planta Med. 64, 511-515

KLINGE, C. M., C. L. BROLLY, R. A. BAMBARA u. R. HILF (1997):

hsp70 is not required for high affinity binding of purified calf uterine estrogen receptor to estrogen response element DNA in vitro.

J. Steroid. Biochem. Mol. Biol. 63, 283-301 KLUCZKA, T. (2003):

Untersuchungen zum Vorkommen östrogenartig wirkender Substanzen in Tränkwasser, Futtermitteln und Stallstaub mit Hilfe eines Reportergenverfahrens.

Hannover, Tierärztl. Hochsch., Diss.

KNIGHT, D. C. u. J. A. EDEN (1996):

A review of the clinical effects of phytoestrogens.

Obstet. Gynecol. 87, 897-904

KOOLMAN, J. u. K.-H. RÖHM (1998):

Hormone.

In: Taschenatlas der Biochemie

Georg Thieme Verlag, Stuttgart, 350 - 359 KORENMAN, S. G. (1969):

Comparative binding affinity of oestrogens and its relation to estrogenic potency.

Steroids 13, 163-177

KORNER, W., V. HANF, W. SCHULLER, C. KEMPTER, J. METZGER u. H. HAGENMAIER (1999):

Development of a sensitive E-screen assay for quantitative analysis of estrogenic activity in municipal sewage plant effluents.

Sci. Total Environ. 225, 33-48 KROMIDAS, S. (1999):

Validierung in der Analytik.

Verlag Wiley-VCH, Weinheim, S. 172-185 KUHNAU, J. (1976):

The flavonoids. A class of semi-essential food components: their role in human nutrition.

World Rev. Nutr. Diet. 24, 117-191

Literaturverzeichnis

KUIPER, G. G., B. CARLSSON, K. GRANDIEN, E. ENMARK, J. HAGGBLAD, S. NILSSON u.

J. A. GUSTAFSSON (1997):

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.

Endocrinology 138, 863-870

KUIPER, G. G., E. ENMARK, M. PELTO-HUIKKO, S. NILSSON u. J. A. GUSTAFSSON (1996):

Cloning of a novel receptor expressed in rat prostate and ovary.

Proc. Natl. Acad. Sci. USA 93, 5925-5930

KUIPER, G. G., J. G. LEMMEN, B. CARLSSON, J. C. CORTON, S. H. SAFE, P. T. VAN DER SAAG, B. VAN DER BURG u. J. A. GUSTAFSSON (1998):

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

Endocrinology 139, 4252-4263

KUIPER, G. G., G. J. VAN DEN BEMD u. J. P. VAN LEEUWEN (1999):

Estrogen receptor and the SERM concept.

J. Endocrinol. Invest. 22, 594-603 KULLING, S. E. u. B. WATZL (2003):

Phytoöstrogene.

Ernährungs-Umschau 50, 234-.239 KUMAR, V. u. P. CHAMBON (1988):

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer.

Cell 55, 145-156

KURZER, M. S. u. X. XU (1997):

Dietary phytoestrogens.

Annu. Rev. Nutr. 17, 353-381

LAMARTINIERE, C. A., J. MOORE, M. HOLLAND u. S. BARNES (1995):

Neonatal genistein chemoprevents mammary cancer.

Proc. Soc. Exp. Biol. Med. 208, 120-123 LAROSA, J. C. (1994):

Metabolic effects of estrogens and progestins.

Fertil. Steril. 62, 140-146

LE GOFF, P., M. M. MONTANO, D. J. SCHODIN u. B. S. KATZENELLENBOGEN (1994):

Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.

J. Biol. Chem. 269, 4458-4466

Literaturverzeichnis

LEGLER, J., C. E. VAN DEN BRINK, A. BROUWER, A. J. MURK, P. T. VAN DER SAAG, A.

D. VETHAAK u. B. VAN DER BURG (1999):

Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line.

Toxicol. Sci. 48, 55-66

LEWIS, R. W., N. BROOKS, G. M. MILBURN, A. SOAMES, S. STONE, M. HALL u. J. ASHBY (2003):

The effects of the phytoestrogen genistein on the postnatal development of the rat.

Toxicol. Sci. 71, 74-83

LIGGINS, J., L. J. BLUCK, W. A. COWARD u. S. A. BINGHAM (1998):

Extraction and quantification of daidzein and genistein in food.

Anal. Biochem. 264, 1-7

LIGGINS, J., L. J. BLUCK, S. RUNSWICK, C. ATKINSON, W. A. COWARD u. S. A.

BINGHAM (2000a):

Daidzein and genistein content of fruits and nuts.

J. Nutr. Biochem. 11, 326-331

LIGGINS, J., L. J. BLUCK, S. RUNSWICK, C. ATKINSON, W. A. COWARD u. S. A.

BINGHAM (2000b):

Daidzein and genistein contents of vegetables.

Br. J. Nutr. 84, 717-725

LIGGINS, J., A. MULLIGAN, S. RUNSWICK u. S. A. BINGHAM (2002):

Daidzein and genistein content of cereals.

Eur. J. Clin. Nutr. 56, 961-966

Analysis of coumestrol, a plant estrogen, in animal feeds by high-performance liquid chromatography.

J. Agric. Food. Chem. 28, 666-667

LUISI, B. F., W. X. XU, Z. OTWINOWSKI, L. P. FREEDMAN, K. R. YAMAMOTO u. P. B.

SIGLER (1991):

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.

Nature 352, 497-505

Literaturverzeichnis

LUNDH, T. (1995):

Metabolism of estrogenic isoflavones in domestic animals.

Proc. Soc. Exp. Biol. Med. 208, 33-39

MARKIEWICZ, L., J. GAREY, H. ADLERCREUTZ u. E. GURPIDE (1993):

In vitro bioassays of non-steroidal phytoestrogens.

J. Steroid. Biochem. Mol. Biol. 45, 399-405

MATSUMURA, A., A. GHOSH, G. S. POPE u. P. D. DARBRE (2005):

Comparative study of estrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells.

J. Steroid. Biochem. Mol. Biol. 94, 431-443

MATSUZAKI, S., T. FUKAYA, T. SUZUKI, T. MURAKAMI, H. SASANO u. A. YAJIMA (1999):

Oestrogen receptor alpha and beta mRNA expression in human endometrium throughout the menstrual cycle.

Mol. Hum. Reprod. 5, 559-564

MAYR, U., A. BUTSCH u. S. SCHNEIDER (1992):

Validation of two in vitro test systems for estrogenic activities with zearalenone, phytoestrogens and cereal extracts.

Toxicology 74, 135-149 MAZUR, W. (1998):

Phytoestrogen content in foods.

Baillieres Clin. Endocrinol. Metab. 12, 729-742 MAZUR, W. u. H. ADLERCREUTZ (1998):

Naturally occuring oestrogens in food.

Pure Appl. Chem. 70, 1759-1776

MAZUR, W., T. FOTSIS, K. WAHALA, S. OJALA, A. SALAKKA u. H. ADLERCREUTZ

MAZUR, W., T. FOTSIS, K. WAHALA, S. OJALA, A. SALAKKA u. H. ADLERCREUTZ