Abu-Absi, Susan Fugett, Linda K. Hansen, and Wei Shou Hu. 2004. “Three-Dimensional Co-Culture of Hepatocytes and Stellate Cells.” Cytotechnology.
Alabraba, Edward B. et al. 2007. “A New Approach to Isolation and Culture of Human Kupffer Cells.” Journal of Immunological Methods 326(1-2): 139–44.
Alpini, Gianfranco, John O. Phillips, Benjamin Vroman, and Nicholas F. Larusso. 1994.
“Recent Advances in the Isolation of Liver Cells.” Hepatology 20(2): 495–514.
Anderson, N.G. 1953. “The Mass Isolation of Whole Cells from Rat Liver.” Science 117(3049): 627–28.
Auphan, Nathalie et al. 1995. “Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis.” Science 270(5234): 286–90.
Auth, M.K. et al. 1998. “Maintained Function of Primary Human Hepatocytes by Cellular Interactions in Coculture : Implications for Liver Support Systems.” Transpl Int. 11(1):
439–43.
Bader, A. et al. 1996. “3-D Coculture of Hepatic Sinusoidal Cells with Primary Hepatocytes
— Design of an Organotypical Model.” Experimental Cell Research 233(226): 223–33.
Badr, Christian et al. 2009. “Real-Time Monitoring of NF-kappaB Activity in Cultured Cells and in Animal Models Christian.” Mol Imaging. 8(5): 278–90.
Bale, Sundhar Shyam, Sharon Geerts, Rohit Jindal, and Martin L Yarmush. 2016. “Isolation and Co-Culture of Rat Parenchymal and Non-Parenchymal Liver Cells to Evaluate Cellular Interactions and Response.” Nature Publishing Group.
Beauloye, V, J M Ketelslegers, B Moreau, and J P Thissen. 1999. “Dexamethasone Inhibits Both Growth Hormone ( GH ) -Induction of Insulin- like Growth Factor-I ( IGF-I ) mRNA and GH Receptor ( GHR ) mRNA Levels in Rat Primary Cultured Hepatocytes.”
Growth Hormone & IGF Research 9: 205–11.
Bhatia, S. N., U. J. Balis, M. L. Yarmush, and M. Toner. 1999. “Effect of Cell-Cell Interactions in Preservation of Cellular Phenotype : Cocultivation of Hepatocytes and ...
Effect of Cell – Cell Interactions in Preservation of Cellular Phenotype : Cocultivation of
LITERATURVERZEICHNIS
117
Hepatocytes and Nonparenchymal Cells.” The FASEB Journal 13: 1883–1990.
Billiar, Timothy R. MD;, and PhD Curran, Ronald D. MD; West, Michael A. MD. 1989.
“Kupffer Cell Cytotoxicity to Hepatocytes in Coculture Requires L-Arginine.” Arch Surg. 124(12): 1416–21.
Blauer, Keith L, Merrily Poth, William M Rogers, and Edward W Bernton. 1991.
“Dehydroepiandrosterone Antagonizes the Suppressive.” Hepatology 129(6): 3174–79.
Bode, Johannes G, and Peter C Heinrich. 2001. “Interleukin-6 Signaling during the Acute-Phase Response of the Liver.” The Liver: Biology and Pathobiology, 4th edn. Lippincott Williams Wilkins, Phil- adelphia: 565–80.
Bojar, H. et al. 1976. “Preparation of Parenchymal and Non-Parenchymal Cells from Adult Human Liver. Morphological and Biochemical Characteristics.” Journal of Clinical Chemistry and Clinical Biochemistry 14: 527–32.
Bouwens, L et al. 1992. “Liver Cell Heterogeneity: Functions of Non-Parenchymal Cells.”
Enzyme. 46(1-3): 155–68.
Brune, K. 1992. Pharmakologie Und Toxikologie. Schattauer, Stuttgart: C. J. Estler.
Bucher, Otto, and Hubert Wartenberg. 1992. Cytologie Histologie Und Mikroskopische Anatomie Des Menschens. 11. Auflag. Bern-Göttingen: Verlag Hans Huber.
Carini, Rita et al. 1995. “Sodium-Mediated Cell Swelling Is Associated with Irrebersible Damage in Isolated Hepatocytes Exposed to Hypoxia or Mitrochondrial Toxins.”
Biochemical and Biophysical Research Communications 206(1): 180–85.
Chen, Grace Y., and Gabriel Nunez. 2011. “Sterile Inflammation : Sensing and Reacting to Damage.” Nat Rev Immunol. 10(12): 826–37.
Copple, Bryan L. 2010. “NIH Public Access.” Liver Int. 30(5): 669–82.
Cvetanovic, Marija, David S Ucker, and Email Alerts. 2004. “Innate Immune Discrimination of Apoptotic Cells: Repression of Proinflammatory Macrophage Transcription Is Coupled Directly to Specific Recognition.” Journal of Immunology (172): 880–89.
D’Acquisto, Fulvio et al. 1997. “Involvement of NF-KB in the Regulation of Cyclooxygenase-2 Protein Expression in LPS-Stimulated J774 Macrophages.” FEBS
118 Letters 418: 175–78.
David M. Mosser; Xia Zhang. 2010. “Activation of Murine Macrophages.” Curr Protoc Immunol CHAPTER: U.
Daynes, Raymond A, and Barbara A Araneo. 1989. “Contrasting Effects of Glucocorticoids on the Capacity of T Cells to Produce the Growth Factors.” Eur. J. Immunol. 19: 2319–
25.
Daynes, Raymond A, Donald J Dudley, and Barbara A Araneo. 1990. “Regulation of Murine Lymphokine Production 11 . Dehydroepiandrosterone Is a Natural Enhancer of Interleukin 2 Synthesis by Helper T Cells *.” : 793–802.
Dekruyff, Rosemarie H, Yu Fang, Dale T Umetsu, and Email Alerts. 1998. “Corticosteroids Enhance the Capacity of Macrophages to Induce Th2 Cytokine Synthesis in CD4 + Lymphocytes by Inhibiting IL-12 Production.” J Im 160(5): 2231–37.
Denson, Lee A et al. 2001. “TNF- α Downregulates Murine Hepatic Growth Hormone Receptor Expression by Inhibiting Sp1 and Sp3 Binding.” 107(11): 1451–58.
Donato, M Teresa, Josi V Castell, and M Josi Gomez-lechn. 1991. “Co-Cultures of Hepatocytes with Epithelial-like Cell Lines: Expression of Drug-Biotransformation Activities by Hepatocytes.” Cell Biology and Toxicology 7(1): 1–14.
Drackley, Jk. 1999. “ADSA Foundation Scholar Award. Biology of Dairy Cows during the Transition Period: The Final Frontier.” Journal of Dairy Science 82(11): 2259–73.
Du, Mi et al. 2016a. “Lower Dosage of Aspirin Promotes Cell Growth and Osteogenic Differentiation in Murine Bone Marrow Stromal Cells.” Journal of Dental Sciences.
———. 2016b. “Lower Dosage of Aspirin Promotes Cell Growth and Osteogenic Differentiation in Murine Bone Marrow Stromal Cells.” Journal of Dental Sciences 11(3): 315–22. http://www.sciencedirect.com/science/article/pii/S1991790216300174 (April 18, 2017).
Dunn, JC, RG Tompkins, and ML Yarmush. 1991. “Long-Term in Vitro Function of Adult Hepatocytes in a Collagen Sandwich Configuration.” Biotechnol Prog. 7: 237–45.
Dunn, JC, ML Yarmush, HG Koebe, and RG Tompkins. 1989. “Hepatocyte Function and
LITERATURVERZEICHNIS
119
Extracellular Matrix Geometry: Long-Term Culture in a Sandwich Configuration.”
FASEB J 3(2): 174–77.
Duque, Guillermo Arango, and Albert Descoteaux. 2014. “Macrophage Cytokines : Involvement in Immunity and Infectious Diseases.” Frontiers in Immunology 5(October): 1–12.
Ehrhardt, Sonja, and Marion Schmicke. 2016. “Isolation and Cultivation of Adult Primary Bovine Hepatocytes from Abattoir Derived Liver.” EXCLI Journal 15: 858–66.
http://dx.doi.org/10.17179/excli2016-794.
Elaut, Greetje et al. 2006. “Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures.” Current Drug Metabolism 7(6): 629–60.
Fernandez, Harvey R, and Sara K Lindén. 2017. “The Aspirin Metabolite Salicylate Inhibits Lysine Acetyltransferases and MUC1 Induced Epithelial to Mesenchymal Transition.”
Scientific Reports 7(5626): 1–12.
Gale, RP, RS Sparkes, and DW Golde. 1978. “Bone Marrow Origin of Hepatic Macrophages (Kupffer Cells) in Humans.” Science 201(4359): 937–38.
Giantin, Mery et al. 2012. “Toxicology in Vitro Primary Hepatocytes as an Useful Bioassay to Characterize Metabolism and Bioactivity of Illicit Steroids in Cattle.” Primary hepatocytes as an useful bioassay to characterize metabolism and bioactivity of illicit steroids in cattle 26(7): 1224–32. http://dx.doi.org/10.1016/j.tiv.2012.06.003.
Godoy, Patricio et al. 2009. “Extracellular Matrix Modulates Sensitivity of Hepatocytes to Fibroblastoid Dedifferentiation and Transforming Growth Factor  –Induced Apoptosis.” Hepatology 49(6): 2031–43.
———. 2010. “Dexamethasone-Dependent versus -Independent Markers of Epithelial to Mesenchymal Transition in Primary Hepatocytes *.” Biol. Chem 391(1): 73–83.
———. 2013. “Recent Advances in 2D and 3D in Vitro Systems Using Primary Hepatocytes, Alternative Hepatocyte Sources and Non-Parenchymal Liver Cells and Their Use in Investigating Mechanisms of Hepatotoxicity, Cell Signaling and ADME.” Archives of Toxicology 87: 1315–1530.
120
Gonçalves, Lígia A, Ana M Vigário, and Carlos Penha-Gonçalves. 2007. “Improved Isolation of Murine Hepatocytes for in Vitro Malaria Liver Stage Studies.” Malaria journal.
Gordon, Siamon. 2008. “Mini-Review Elie Metchnikoff : Father of Natural Immunity.” Eur.
J. Immunol. 38: 3257–64.
Gordon, Siamon, and Fernando O. Martinez. 2010. “Alternative Activation of Macrophages:
Mechanism and Functions.” Immunity 32(5): 593–604.
http://dx.doi.org/10.1016/j.immuni.2010.05.007.
Goulet, Francine, Claire Normand, and Odette Morin. 1988. “Cellular Interactions Promote Tissue-Specific Function , Biomatrix Deposition and Junctional Communication of Primary Cultured Hepatocytes.” Hepatology 8(5): 1010–18.
Green, Charlotte J et al. 2017. “The Isolation of Primary Hepatocytes from Human Tissue : Optimising the Use of Small Non-Encapsulated Liver Resection Surplus.” Cell and Tissue Banking 18(4): 597–604. "http://dx.doi.org/10.1007/s10561-017-9641-6.
Guguen-Guillouzo, C., M. Bourel, and A. Guillouzo. 1986. “Human Hepatocyte Cultures.”
Prog Liver Dis 8: 33–50.
Guguen-Guillouzo, C., and A Guillouzo. 2010. “General Review on in Vitro Hepatocyte Models and Their Applications.” Methods in molecular biology 640: 1–40.
Guo, Ren, Xinxiu Xu, Yuting Lu, and Xin Xie. 2017. “Physiological Oxygen Tension Reduces Hepatocyte Dedifferentiation in in Vitro Culture.” Scientific Reports (July): 1–
9. http://dx.doi.org/10.1038/s41598-017-06433-3.
Haubrich, William S. 2004. “Kupffer of Kupffer Cells.” Gastroenterology 127(1): 16.
http://www.sciencedirect.com/science/article/pii/S0016508504009679.
He, Meifang et al. 2015. “Fluorescence-Activated Cell Sorting Structures.” Scientific Reports 5: 1–6.
Hennebold, Jon D., and Raymond A. Daynes. 1994. “Regulation of Macrophage Dehydroepiandrosterone Sulfate Metabolism by Inflammatory Cytokines.”
Endocrinology 135(1): 67–75.
Herman, James P et al. 2016. “Regulation of the Hypothalamic-Pituitary-Adrenocortical
LITERATURVERZEICHNIS
121 Stress Response.” Compr Physiol . 6(2): 603–21.
Hespeling, Ursula, Kurt Jungermann, and P Puschel. 1995. “Feedback-Inhibition of Glucagon-Stimulated Glycogenolysis in HepatocyteKupffer Cell Cocultures by Glucagon-Elicited Prostaglandin Production in Kupffer Cells.” Hepatology 22(5): 1577–
83.
Higgins, Debra F et al. 2007. “Hypoxia Promotes Fibrogenesis in Vivo via HIF-1 Stimulation of Epithelial-to-Mesenchymal Transition.” The Journal of Clinical Investigation 117(12): 3810–20.
Hoebe, Kasper H N et al. 2001. “Direct Cell-to-Cell Contact between Kupffer Cells and Hepatocytes Augments Endotoxin-Induced Hepatic Injury.” Am J Physiol Gastrointest Liver Physiol: 720–28.
Holtmann, Henrik, and Monika Bobkowski. 2009. BASIC Histologie.
Ibrini, J. et al. 2012. “Albumin-Induced Epithelial Mesenchymal Transformation.”
Experimental Nephrology 120: 91–102.
Ikeda, Tetsuo et al. 1992. “Ischemic Injury in Liver Transplantation: Difference in Injury Sites Between Warm and Cold Ischemia in.” ISCHEMIC INJURY IN LIVER TRANSPLANTATION 16(2): 454–61.
Inoue, Yusuke et al. 2002. “Defective Ureagenesis in Mice Carrying a Liver-Specific Disruption of Hepatocyte Nuclear Factor 4 α : HNF4 α Regulates Ornithine Transcarbamylase in Vivo.” JBC Papers (301).
Inoue, Yusuke, Ai-ming Yu, Junko Inoue, and Frank J Gonzalez. 2004. “Hepatocyte Nuclear Factor 4 ␣ Is a Central Regulator of Bile Acid Conjugation *.” The Journal of Biological Chemestry 279(4): 2480–89.
Iwasaki, Yasumasa et al. 2004. “Dehydroepiandrosterone-Sulfate Inhibits Nuclear Possibly through Antioxidant Effect.” 89(7): 3449–54.
Joest, Ernst. 1937. Ernst Joest’s Handbuch Der Speziellen Pathologischen Anatomie Der Haustiere. 2. Auflage. Berlin Schoetz: Walter Frei.
Kalluri, Raghu, and Robert A Weinberg. 2009. “Review Series The Basics of
Epithelial-122
Mesenchymal Transition.” The Journal of Clinical Investigation 119(6): 1420–28.
Karow, Thomas, and Ruth Lang-Roth. 1999. Allgemeine Und Spezielle Pharmakologie Und Toxikologie.
Kaufmann, Stefan H. E. 2008. “100 Jahre Nobelpreis Elie Metchnikoff Und Paul Ehrlich.”
BIOspektrum 8: 660–61.
Keller, Maren et al. 2009. “A Circadian Clock in Macrophages Controls Inflammatory Immune Responses.” PNAS 106(50): 21407–12.
Khetani, Salman R, and Sangeeta N Bhatia. 2008. “Microscale Culture of Human Liver Cells for Drug Development.” nature biotechnology 26(1): 120–26.
Kmiec. 2001. Cooperation of Liver Cells in Health and Disease. 161:III–XI ed. Adv. Anat.
Embryol. Cell Biol.
Knook, D. L., and E. Ch Sleyster. 1976. “Separation of Kupffer and Endothelial Cells of the Rat Liver by Centrifugal Elutriation.” Experimental Cell Research 99(2): 444–49.
Kobayashi, Y et al. 1999. “Reduced Growth Hormone Receptor ( GHR ) Messenger Ribonucleic Acid in Liver of Periparturient Cattle Is Caused by a Specific Down-Regulation of GHR 1A That Is Associated with Decreased Insulin-Like Growth Factor I
*.” Endocrinology 140(9): 3947–54.
Koike, Masahiko, Michiaki Matsushita, Koichi Taguchi, and Junichi Uchino. 1996. “Function of Culturing Monolayer Hepatocytes by Collagen Gel Coating and Coculture with Nonparenchymal Cells.” Arrificial Organs Boston International Society for Artificial Organs 20(0).
König, Horst Erich, and Hans-Georg Liebich. 2012. Anatomie Der Haussäugetiere. 5.
Auflage. Stuttgart, New York: Schattauer.
Krappmann, Daniel, and Claus Scheidereit. 1997. “NF-KB and Signal Transduction Regulation of NF-KB Activity by IKBa and IKB~ Stability.” Immunbiology 198: 3–13.
Krause, Petra, Farahnaz Saghatolislam, and Sarah Koenig. 2009. “Maintaining Hepatocyte Differentiation in Vitro through Co-Culture with Hepatic Stellate Cells.” : 205–12.
Kren, Betsy T., and Clifford J Steer. 1996. “Regulation of Gene Expression in
LITERATURVERZEICHNIS
123
Posttranscriptional Liver Regeneration : Role of mRNA Stability.” The FASEB Journal 10: 559–73.
Kuhnert, Nikolai. 2000. “Hundert Jahre Aspirin ® Die Geschichte Des Wohl Erfolgreichsten Medikaments Des Letzten Jahrhunderts.” Pharmazie unserer Zeit (1): 32–39.
Kutuk, Ozgur, and Huveyda Basaga. 2003. “Aspirin Prevents Apoptosis and NF- κ B Activation Induced by H O in HeLa Cells Aspirin Prevents Apoptosis and NF- K B Activation Induced by H 2 O 2 in HeLa Cells.” Free Radical Research 37(12): 1267–76.
Labrie, C, G Pelletier, and J Simard. 2005. “STARLING REVIEW Is Dehydroepiandrosterone a Hormone?” 187: 169–96.
Lawrence, Toby. 2009. “Inflammation.” Cold Spring Harbor Laboratory Press 1(6): 1–10.
Lelbach, Adam, Jens-gerd Scharf, and Giuliano Ramadori. 2001. “Regulation of Insulin-like Growth Factor-I and of Insulin-like Growth Factor Binding Protein-1 , -3 and -4 in Cocultures of Rat Hepatocytes and Kupffer Cells by Interleukin-6.” Journal of Hepatology 35: 558–67.
Loor, Juan J et al. 2005. “Temporal Gene Expression Profiling of Liver from Periparturient Dairy Cows Reveals Complex Adaptive Mechanisms in Hepatic Function.” Physiol.
Genomics 23: 217–26.
Loria, Padgett. 1992. “Mobilization of Cutaneous Immunity for Systemic Protection Against Infections.” : 4.
Lucy, M.C., C.K. Boyd, .A.T. Koenigsfeld, and C.S. Okamura. 1998. “Expression of Somatotropin Receptor Messenger Ribonucleic Acid in Bovine Tissues.” Journal of Dairy Science 81(8): 1889–95.
Mátis, G et al. 2016. “Porcine hepatocyte–Kupffer Cell Co-Culture as an in Vitro Model for Testing the Efficacy of Anti-Inflammatory Substances.” Journal of Animal Physiology and Animal Nutrition 101(2): 201–7.
Meyer, Christoph et al. 2013. “Distinct Dedifferentiation Processes Affect Caveolin-1 Expression in Hepatocytes.” Cell Communication and Signaling (11): 1–13.
Miller, Walter L. 2002. “Androgen Biosynthesis from Cholesterol to DHEA.” Molecular and
124
Cellular Endocrinology 198: 7?/ 14 www.elsevier.com/locate/mce.
Mills, CD. 2001. “Macrophage Arginine Metabolism to Ornithine/urea or Nitric Oxide/citrulline: A Life or Death Issue.” Crit Rev Immunol. 21(5): 399–425.
Milosevic, Nenad, Hanspeter Schawalder, and Peter Maier. 1999. “Kupffer Cell-Mediated Differential down-Regulation of Cytochrome P 450 Metabolism in Rat Hepatocytes.”
European Journal of Pharmacology 368: 75–87.
Miltenyi, Stefan, Werner Muller, Walter Weichel, and Andreas Radbruch. 1990. “High Gradient Magnetic Cell Separation With MACS.” Cytometry 11: 231–38.
Mohn, Kenneth L et al. 1991. “The Gene Encoding Rat Insulinlike Growth Factor-Binding Protein 1 Is Rapidly and Highly Induced in Regenerating Liver.” Molecular and Cellular Biology 11(3): 1393–1401.
Moshage, Han j., Hans J.W. de Haard, Hans M.G. Princen, and Sing Hiem Yap. 1985. “The Influence of Glucocorticoid on Albumin Synthesis and Its Messenger RNA in Rat in Vivo and in Hepatocyte Suspension Culture.” Division of Gastrointestinal and Liver Disease 824: 27–33.
Mosser, David M, and Justin P Edwards. 2009. “Exploring the Full Spectrum of Macrophage Activation.” Nat Rev Immunol. 8(12): 958–69.
Mozo, L., A. Suárez, and C Gutiérrez. 2004. “Glucocorticoids up-Regulate Constitutive Interleukin-10 Production by Human Monocytes.” Clinical and Experimental Allergy 34:
406–12.
Murphy, Eric J, and Lloyd A Horrocks. 1993. “Mechanisms of Hypoxic and Ischemic Injury Use of Cell Culture Models.” Molecular and Chemical Neuropathology 19: 95–106.
Nguyen, Theresa V. et al. 2015. “Establishment of a Hepatocyte-Kupffer Cell Co-Culture Model for Assessment of Proinflammatory Cytoki .... Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transp.” Drug Metab Rev. 43: 774–85.
O’Neill, Kathy E et al. 2014. “Hepatocyte-Ductal Transdifferentiation Is Mediated by Reciprocal Repression of SOX9 and C/EBPa.” CELLULAR REPROGRAMMING 16(5):
LITERATURVERZEICHNIS
125 314–23.
Olinga, Peter et al. 1998. “Effect of Human Liver Source on the Functionality of Isolated Hepatocytes and Liver Slices.” Drug Metabolism and Disposition 26(1): 5–11.
Olynyk, John k., and Sharon L. Clarke. 1998. “Kupffer Cell Purification.” Gastroenterology and Hepatology 13(8): 843–45.
Padgett, D a, and R M Loria. 1998. “Endocrine Regulation of Murine Macrophage Function:
Effects of Dehydroepiandrosterone, Androstenediol, and Androstenetriol.” Journal of neuroimmunology 84(1): 61–68. http://www.ncbi.nlm.nih.gov/pubmed/9600709.
Pagan, Roser, Miquel Llobera, Isabel Marti, and Senén Vilaró. 1997. “Epithelial-Mesenchymal Transition of Cultured Rat Neonatal Hepatocytes Is Differentially Regulated in Response to Epidermal Growth Factor and Dimethyl Sulfoxide.”
Hepatology 25(3): 598–606.
Paine, Alan J, and Evangelos Andreakos. 2004. “Activation of Signalling Pathways during Hepatocyte Isolation : Relevance to Toxicology in Vitro.” Toxicology in Vitro 18: 187–
93.
Panda, Santanu et al. 2015. “In Vitro Culture of Functionally Active Buffalo Hepatocytes Isolated by Using a Simplified Manual Perfusion Method.” PLOS ONE 10: 1–17.
Petrasek, Jan et al. 2012. “Interferon Regulatory Factor 3 and Type I Interferons Are Protective in Alcoholic Liver Injury in Mice via Cross-Talk of Parenchymal and Myeloid Cells.” Hepatology 53(2): 649–60.
Pfeiffer, Elisa et al. 2015. “Isolation , Characterization , and Cultivation of Human Hepatocytes and Non-Parenchymal Liver Cells.” Experimental Biology and Medicine 240(5): 645–56.
Podhaisky, Hans Peter et al. 1997. “Aspirin Protects Endothelial Cells from Oxidative Stress - Possible Synergism with Vitamin E.” FEBS Letters.
Powanda, M.C., R.W. Wannemacher, JR. Cockerell, and CockerellG.L. 1972. “Nitrogen Metabolism and Protein Synthesis During Pneumococcal Sepsis in Rats.” Infection and Immunity 6(3): 266–71.
126
Queral, A. E., A. B. DeAngelo, and Garret; C. T. 1984. “Effect of Different Collagenases on the Isolation of Viable Hepatocytes from Rat Liver.” Analytical Biochemestry 138: 235–
37.
Renaville, R, M Hammadi, and D Portetelle. 2002. “Role of the Somatotropic Axis in the Mammalian Metabolism.” Domestic Animal Endocrinology 23: 351–60.
Roitt, Ivan M., Jonatha Brostoff, and David K. Mall. 1993. Kurzes Lehrbuch Der Immunologie. 3. Auflage. Stuttgart, New York: Thieme Georg Verlag.
Rose, Kelly A. et al. 2017. “Co-Culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity Kelly.” J Pharm Sci 105(2):
950–64.
Ruoff, BM, and WL Daniel. 1991. “Comparative Biochemistry of Mammalian Arylsulfatase C and Steroid Sulfatase.” Comp Biochem Physiol B. 98(2-3): 313–22.
Sakitani, Kazushige et al. 1997. “The Anti-Inflammatory Drug Sodium Salicylate Inhibits Nitric Oxide Formation Induced by Interleukin-1 B at a Translational Step , but Not at a Transcriptional Step , in Hepatocytes.” Hepatology 25(2): 416–20.
Salomon, Franz-Viktor, Hans Geyer, and Uwe Gille. 2015. Anatomie Für Die Tiermedizin. 3.
Auflage. Enke Ferdinand.
Scharf, Jens-Gerd, Giuliano Ramadori, Thomas Braulke, and Heinz Hartmann. 1996.
“Synthesis of Insulinlike Growth Factor Binding Proteins and of the Acid-Labile Subunit in Primary Cultures of Rat Hepatocytes , of Kupffer Cells , and in Cocultures : Regulation by Insulin , Insulinlike Growth Factor , and Growth Hormone.” Hepatology 23(4): 818–27.
Scheinman, Robert I., Patricia C. Cogswell, Alan K. Lofquist, and Albert S. Baldwin Jr. 1995.
“Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids.” Science 270(5234): 283–86.
Schemmer, P. et al. 2005. “Spezielle Aspekte Des Ischämie-/Reperfusionsschadens Bei Der Leber.” TRANSPLANTLINC 10: 32–43.
Seglen, PO. 1976. “Preparation of Rat Liver Cells.” Methods Cell Biol. 13: 29–83.
LITERATURVERZEICHNIS
127
Selzner, Markus, Carlos A. Camargo, and Pierre-Alain Clavien. 1999. “Ischemia Impairs Liver Regeneration After Major Tissue Loss in Rodents : Protective Effects of Interleukin-6.” Hepatology 30(2): 469–75.
Selzner, Nazia et al. 2003. “ICAM-1 Triggers Liver Regeneration Through Leukocyte.”
Gastroenterology 124: 692–700.
Severgnini, Mariano et al. 2012. “A Rapid Two-Step Method for Isolation of Functional Primary Mouse Hepatocytes: Cell Characterization and Asialoglycoprotein Receptor Based Assay Development.” Cytotechnology.
Shimaoka, Satoru, Toshikazu Nakamura, and Akira Ichihara. 1987. “Stimulation Hepatocytes of Growth of Primary Cultured Adult Rat without Growth Factors by Coculture with Nonparenchymal Liver Cells ’.” Experimental Cell Research 172: 228–42.
Shin, Sangyun, Hee-jung Im, Yeo-jung Kwon, and Dong-jin Ye. 2017. “Human Steroid Sulfatase Induces Wnt / β-Catenin Signaling and Epithelial-Mesenchymal Transition by Upregulating Twist1 and HIF-1 α in Human Prostate and Cervical Cancer Cells.”
Oncotarget 8(37): 61604–17.
Smedsrød, Bård, Håkan Pertoft, Gösta Eggertsen, and Christer Sundström. 1985. “Functional and Morphological Characterization of Cultures of Kupffer Cells and Liver Endothelial Cells Prepared by Means of Density Separation in Percoll, and Selective Substrate Adherence.” Cell and Tissue Research.
Smith, William L, David L Dewitt, and R Michael Garavito. 2000. “C YCLOOXYGENASES : Structural , Cellular , and.” Annu. Rev. Biochem. 69(1): 145–82.
Späth, Gerald F, and Mary C Weiss. 1998. “Hepatocyte Nuclear Factor 4 Provokes Expression of Epithelial Marker Genes, Acting As a Morphogen in Dedifferentiated Hepatoma Cells.” The Journal of Clell Biology 140(4): 935–46.
Stein, By Michael, Satish Keshav, Neil Harris, and Siamon Gordon. 1992. “Interleukin 4 Potently Enhances Murine Macrophage Mannose Receptor Activity: A Marker of Alternative Immunologic Macrophage Activation.” Journal of Experimental Medicine 176: 287–92.
Stout, R. D. et al. 2005. “Macrophages Sequentially Change Their Functional Phenotype in
128
Response to Changes in Microenvironmental Influences.” The Journal of Immunology 175(1): 342–49. http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.175.1.342.
Strutz, Frank et al. 2002. “Role of Basic Fibroblast Growth Factor-2 in Epithelial-Mesenchymal Transformation.” Kidney International 61: 1714–28.
Thiery, Jean Paul, and Jonathan P Sleeman. 2006. “Complex Networks Orchestrate Epithelial – Mesenchymal Transitions.” Molecular Cell Biology 7(February): 131–42.
Tizard, Ian R. 2009. Veterinary Immunology. 8. Auflage. Saunders Elsevier.
Traish, Abdulmaged M., PacoMA Kang, FaridDVM Saad, and Andre T.MD Guay. 2011.
“Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology (CME).” The Journal of Sexual Medicine 8(11): 2960–82.
Vinken, Mathieu et al. 2014. “Primary Hepatocytes and Their Cultures in Liver Apoptosis.”
Arch Toxicol. 88(2): 199–212.
Voll, Reinhard E et al. 1997. “Immunosuppressive Effects of Apoptotic Cells Why Parent Birds Play Favourites.” NATURE 534(1988): 0–1.
Wagle, S.R., Friedrich Hofmann, and Karl Decker. 1976. “Studies on Urea Synthesis, Insulin Degradation and Phagocytosis by Isolated Rat Kupffer Cells.” Biochemical and Biophysical Research Communications 72(2): 448–55.
West, Michael A et al. 1989. “Evidence That Rat Kupffer Cells Stimulate and Inhibit Hepatocyte Protein Synthesis In Vitro by Different Mechanisms.” Gastroenterology (96): 1572–82.
Witte, Stefanie, Yette Brockelmann, and Marion Schmicke. 2017. “Kultivierung Primärer Boviner Hepatozyten Und Einflussfaktoren Auf Zellzahl Und Viabilität Der Gewonnen Zellen.” In Internes Symposium Zu „Ersatz- Und Ergänzungsmethoden Zum Tierversuch“ Der Tierärztlichen Hochschule Hannover; 02.02.2017.,.
Witte, Stefanie, Teresa Fischbach, Yette Brockelmann, and Marion Schmicke. 2018.
“Influence of Glucose and Macrophages on Growth Hormone Receptor Expression in Primary Bovine Hepatocytes.” In 8th International Congress on Endocrinology.
01.12.2018-04.12.2018.,.
LITERATURVERZEICHNIS
129
Wu, Rongqian et al. 2006. “Suppression of Hepatocyte CYP1A2 Expression by Kupffer Cells via AhR Pathway : The Central Role of Proinflammatory Cytokines.” INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (18): 339–46.
Wynn, Thomas A., Ajay Chawla, and Jeffrey W. Pollard. 2014. “Origins and Hallmarks of Macrophages: Development, Homeostasis, and Disease.” Nature. 496(7446): 445–55.
Yamada, Shiro, Patricia S Otto, Diana L Kennedy, and Thomas F Whayne. 1980. “The Effects of Dexamethasone on Metabolic Activity of Hepatocytes in Primary Monolayer Culture.” In Vitro 16(7): 559–70.
Yoo, Chul-gyu et al. 2001. “Effect of Acetylsalicylic Acid on Endogenous I B Kinase Activity in Lung Epithelial Cells.” Am J Physiol Lung Cell Physiol: 1–3.
Zeng, Wei-Qun et al. 2013. “A New Method to Isolate and Culture Rat Kupffer Cells.” PLoS
Zeng, Wei-Qun et al. 2013. “A New Method to Isolate and Culture Rat Kupffer Cells.” PLoS