7. ANHANG
7.1 Tabellarische Auswertung der Microarray-Analysen
Tabelle 7.1: Vergleich aller mit AGE-BSA behandelten Fibroblasten mit unbehandelten Fibroblasten Gene Title Ratio of medians (b/a) MW_bvsa_all -
Mann-Whitney_Change Direction
Representative Public
ID Gene Ontology
Biological Process Primersequenzen
NADPH oxidase 4 0.506 Down NM_016931 electron transport ctt ccg ttg gtt tgc aga tt
tgaatt ggg tcc aca aca ga tga act atg agg tca gcc tct g
tgt atg gtt tcc agt cat cca a pleckstrin homology,
Sec7 and coiled-coil domains 4
0.576 Down AF125349 ---
cyclin F 0.661 Down U17105 cytokinesis
Kinesin family member
C1 0.692 Down BC000712 mitotic sister chromatid
segregation contactin associated
protein 1
0.7 Down NM_003632 cell adhesion
RAP2A, member of
RAS oncogene family 1.42 Up NM_002886 signal transduction
cathepsin L2 1.431 Up AF070448 proteolysis and
peptidolysis tct tga ttg cgg gga cta ac gcc ttg cct gag aca aac tc ccc aga atg ccg aga tga ta cac ttg agg cca aga gtt ga solute carrier family 3
(activators of dibasic and neutral amino acid transport), member 2
1.45 Up NM_002394 amino acid transport tct tga ttg cgg gga cta ac
gcc ttg cct gag aca aac tc ccc aga atg ccg aga tga ta cac ttg agg cca aga gtt ga TRAF family
member-associated NFKB activator
1.455 Up BC003388 signal transduction ggc gag caa ctc aat aaa gc
agc aga gga aca cag cca taa act tct tgt gaa ttc cac tca aga ttt ctt gtt tca ctg tct tca agc
polymerase (DNA-directed), delta interacting protein 3
1.478 Up Z93241 ---
ligase IV, DNA, ATP-dependent
1.482 Up NM_002312 DNA recombination
protein tyrosine phosphatase, non-receptor type 12
1.494 Up S69182 protein amino acid
dephosphorylation serine/threonine kinase
4
1.509 Up Z25430 apoptosis
tumor necrosis factor receptor superfamily, member 10b
1.525 Up AF153687 activation of
NF-kappaB-inducing kinase
syntaxin 3A 1.544 Up AJ002077 ---
sphingomyelin
phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)
1.546 Up M59917 --- gga tcg agg aga caa agt gc
cca gct cca gct ctt cag ac
NAD(P)H dehydrogenase, quinone 1
1.558 Up NM_000903 electron transport nitric
oxide biosynthesis aaa gga ccc ttc cgg agt aa cca tcc ttc cag gat ttg aa solute carrier family 4,
sodium bicarbonate cotransporter, member 7
1.57 Up NM_003615 anion transport gtt ggc gtt atg ttg gga gt
gta acc cgc tgt tca cga at tag aag cag cgc tga aag g ggg aga ggc caa aat acc tg intestinal cell (MAK-like)
kinase
1.582 Up NM_014920 development
NAD(P)H dehydrogenase, quinone 1
1.608 Up AI039874 electron transport
calcitonin gene-related peptide-receptor component protein
1.621 Up NM_014478 acrosome reaction
thioredoxin reductase 1 1.644 Up NM_003330 electron transport agg tgg ctc agg agg tct g
cag gac cat cac ctt ctt gc popeye domain
containing 3 1.659 Up NM_022361 ---
tripartite motif-containing 16
1.66 Up NM_006470 ---
peroxisome proliferative activated receptor, alpha
1.68 Up NM_005036 energy pathways
homeodomain
interacting protein kinase 2
1.897 Up NM_022740 induction of apoptosis
by intracellular signals positive regulation of
JNK cascade
cgg gag ttc att gac ctg tt aaa ggg gtt ttg ctc tgg tt
glutamate-cysteine
ligase, modifier subunit 2.009 Up NM_002061 cysteine metabolism
KIT ligand 2.115 Up NM_000899 cell adhesion gga tgg atg ttt tgc caa gt
tct ttc acg cac tcc aca ag
KIT ligand 2.156 Up AF119835 cell adhesion ttt gcc aag tca ttg ttg ga
ggt tct ggg ctc ttg aat ga ctt caa cat taa gtc ctg aga aag g agc caa tta taa gag aaa aca atg c heme oxygenase
(decycling) 1 3.071 Up NM_002133 heme oxidation positive
regulation of I-kappaB
kinase/NF-kappaB cascade
atg aca cca agg acc aga gc gtg taa gga ccc atc gga ga ggg tga tag aag agg cca aga
agc tcc tgc aac tcc tca aa
Tabelle 7.2: Vergleich der mit AGE-BSA behandelten alten Fibroblasten mit unbehandelten alten Fibroblasten Gene Title Ratio of medians (b/a) MW_bvsa_alt -
Mann-Whitney_Change Direction
Representative Public ID
Gene Ontology Biological Process pleckstrin homology,
Sec7 and coiled-coil domains 4
0.396 Down AF125349 --- ctg cct gga gct cta caa cc
gct tgc tgg caa tct tct tc
claudin 10 0.399 Down NM_006984 cell adhesion
NADPH oxidase 4 0.401 Down NM_016931 electron transport gat cat cgc ctt cat ggt ct
gct gac agc agc gat cat aa fibroblast growth
factor receptor 3 (achondroplasia, thanatophoric dwarfism)
0.522 Down NM_000142 JAK-STAT cascade ctg aaa gac gat gcc act ga
aca cca ggt cct tga agg tg
epoxide hydrolase 1, microsomal
(xenobiotic)
1.587 Up NM_000120 aromatic compound
catabolism
ctg aaa gac gat gcc act ga aca cca ggt cct tga agg tg BCL2-associated X
protein 1.595 Up NM_004324 apoptosis
TRAF family member-associated NFKB activator
1.596 Up BC003388 signal transduction ggc gag caa ctc aat aaa gc
agc aga gga aca cag cca taa act tct tgt gaa ttc cac tca aga ttt ctt gtt tca ctg tct tca agc IQ motif containing
GTPase activating protein 1
1.604 Up AI679073 signal transduction
splicing factor, arginine/serine-rich 5
1.721 Up U30884 mRNA splice site
selection GM2 ganglioside
activator
1.724 Up X61094 glycolipid catabolism gag aga gcg tta ccc ctg tg
aga gac ggc cat agc act gt coatomer protein
complex, subunit alpha
1.724 Up AI621079 ER to Golgi transport gag aga gcg tta ccc ctg tg
aga gac ggc cat agc act gt thioredoxin reductase
1
1.735 Up NM_003330 electron transport
RAP2A, member of RAS oncogene family /// RAP2B, member of RAS oncogene family
1.745 Up NM_002886 signal transduction ggc gag caa ctc aat aaa gc
agc aga gga aca cag cca taa act tct tgt gaa ttc cac tca aga ttt ctt gtt tca ctg tct tca agc somatostatin receptor
1
1.767 Up NM_001049 G-protein signaling,
coupled to cyclic nucleotide second
messenger
tcc ttc ctc ctc tcc tag cc gta gat gtt ggt ggc cgt ct
carnitine
palmitoyltransferase 1A (liver)
1.824 Up NM_001876 fatty acid beta-oxidation tcg tca cct ctt ctg cct tt
aca cac cat agc cgt cat ca popeye domain
containing 3
1.831 Up NM_022361 --- tcc ttc ctc ctc tcc tag cc
gta gat gtt ggt ggc cgt ct splicing factor,
arginine/serine-rich 15 1.846 Up AA648521 ---
phosphogluconate dehydrogenase ///
phosphogluconate dehydrogenase
1.857 Up NM_002631 pentose-phosphate
shunt, oxidative branch
cathepsin L2 1.86 Up AF070448 proteolysis and
peptidolysis
gaa agc gct ggt tta tct cg tct tcc gtg tgc ttc ctt ct chondroitin sulfate
proteoglycan 6 (bamacan)
1.875 Up BF795297 DNA repair gaa agc gct ggt tta tct cg
tct tcc gtg tgc ttc ctt ct
alpha-fetoprotein 1.883 Up NM_001134 immune response agc ttg gtg gtg gat gaa ac ccc tct tca gca aag cag ac hypothetical protein
FLJ30656 1.901 Up BF197707 --- agc ttg gtg gtg gat gaa ac
ccc tct tca gca aag cag ac golgi associated,
gamma adaptin ear containing, ARF binding protein 2
1.914 Up AI799984 intra-Golgi transport
TAF13 RNA
polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
1.987 Up NM_005645 regulation of
transcription, DNA-dependent
homeodomain interacting protein kinase 2
2.015 Up NM_022740 induction of apoptosis
by intracellular signals positive regulation of JNK cascade positive
regulation of transforming growth factor beta receptor signaling pathway
cgg gag ttc att gac ctg tt aaa ggg gtt ttg ctc tgg tt
protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
2.024 Up L07527 intracellular signaling
cascade
KIAA0674 2.033 Up AA628140
protein kinase N2 2.043 Up AF118089 protein amino acid
phosphorylation caspase 2,
apoptosis-related cysteine protease
2.053 Up U13022 apoptotic program
tripartite
motif-containing 16 2.089 Up NM_006470 ---
ecotropic viral
integration site 5 2.11 Up NM_005665 cell proliferation
chromosome 14 open reading frame 106
2.142 Up NM_018353 ---
glutamate-cysteine ligase, modifier subunit
2.259 Up NM_002061 cysteine metabolism
NAD(P)H dehydrogenase, quinone 1
2.267 Up NM_000903 electron transport
interleukin 6 signal transducer (gp130, oncostatin M receptor)
2.269 Up BE856546 cell surface receptor
linked signal transduction
KIAA0217 2.311 Up AW628686 ---
KIT ligand 2.314 Up NM_000899 cell adhesion gga tgg atg ttt tgc caa gt
tct ttc acg cac tcc aca ag interleukin 6 signal
transducer (gp130, oncostatin M receptor)
2.363 Up AB015706 cell surface receptor
linked signal transduction
KIAA1212 2.453 Up NM_017571 ---
chromosome 6 open
reading frame 106 2.559 Up NM_024294
KIT ligand 2.589 Up AF119835 cell adhesion gaa tga cag cag tag cag taa taga
atg gct gcc cag tgt agg NAD(P)H
dehydrogenase, quinone 1
2.657 Up AI039874 electron transport aaa gga ccc ttc cgg agt aa
cca tcc ttc cag gat ttg aa
zinc finger protein 484 2.901 Up BE567977 ---
heme oxygenase
(decycling) 1 3.341 Up NM_002133 heme oxidation
positive regulation of I-kappaB
kinase/NF-kappaB cascade
atg aca cca agg acc aga gc gtg taa gga ccc atc gga ga ggg tga tag aag agg cca aga
agc tcc tgc aac tcc tca aa pirin (iron-binding
nuclear protein) 3.348 Up NM_003662 transcription from Pol II
promoter gga tgg tgt gac agt tgc tg ctt ggg atc ctt gtt ctc ca solute carrier family 7,
(cationic amino acid transporter, y+
system) member 11
3.817 Up NM_014331 amino acid transport ggc agt gac ctt ttc tga gc
tgt caa agg gtg caa aac aa aat gcc cag ata tgc atc gt agg aaa aca aag ctg gga tg solute carrier family 6
(neurotransmitter transporter, taurine), member 6
5.18 Up NM_003043 amino acid metabolism tga gga ggc cct ata gca ga
ctc ctt ctc tgc ctg gaa tg tct gag gag ctc cca aac aa tgt cct tgt gga aat ctt tca g
Tabelle 7.3: Vergleich der mit AGE-BSA behandelten jungen Fibroblasten mit unbehandelten jungen Fibroblasten Gene Title Ratio of medians (b/a) MW_bvsa_jung -
Mann-Whitney_Change Direction
Representative Public ID Gene Ontology Biological Process
homeo box A3 /// homeo box A3 0.297 Down NM_030661 development
--- 0.495 Down AK022045 ---
tudor domain containing 3 0.504 Down AU156998 ---
cAMP responsive element binding protein 5
0.519 Down NM_004904 positive regulation of transcription,
DNA-dependent carbohydrate
(N-acetylglucosamine 6-O) sulfotransferase 4
0.651 Down NM_005769 cell adhesion
CGI-125 protein 0.66 Down NM_016060 regulation of transcription,
DNA-dependent
centromere protein A, 17kDa 0.663 Down BC002703 chromosome organization and
biogenesis (sensu Eukaryota) F-box and leucine-rich repeat
protein 6
0.672 Down NM_024555 ubiquitin cycle
Hypothetical protein FLJ20331 0.684 Down AL390149 ---
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
0.703 Down NM_004106 cell surface receptor linked signal
transduction RNA polymerase II associated
protein 1
0.708 Down NM_015540 ---
hypothetical protein MGC32020 0.717 Down BC003535 ---
nuclear transcription factor Y, alpha 1.511 Up AL031778 regulation of transcription,
DNA-dependent
--- 1.529 Up L37198 ---
RAB GTPase activating protein 1-like
1.584 Up AB019490 ---
hypothetical protein FLJ11127 1.716 Up NM_019018 ---
chemokine (C-C motif) ligand 17 1.725 Up NM_002987 G-protein coupled receptor protein
signaling pathway transcobalamin I (vitamin B12
binding protein, R binder family)
1.898 Up NM_001062 cobalamin transport
calpain 2, (m/II) large subunit 1.95 Up AK023851 proteolysis and peptidolysis
lymphotoxin beta (TNF superfamily, member 3)
3.075 Up NM_002341 cell-cell signaling
--- 5.617 Up U08626 ---
--- 12.821 Up NM_018613 ---
Tabelle 7.4: Vergleich der alten unbehandelten Fibroblasten mit jungen unbehandelten Fibroblasten
Gene Title Ratio of medians
(alt_a/jung_a)
MW_altavsjunga - Mann-Whitney_Change Direction
Representative Public ID Gene Ontology Biological Process
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)
0.254 Down NM_014291 amino acid metabolism
four and a half LIM domains 1 0.376 Down AF098518 cell differentiation
NACHT, leucine rich repeat and PYD containing 1
0.423 Down NM_021730 caspase activation
four and a half LIM domains 1 0.427 Down U29538 cell differentiation
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
0.439 Down AF021233 apoptosis
a disintegrin and metalloproteinase domain 19 (meltrin beta)
0.458 Down AF311317 proteolysis and peptidolysis
four and a half LIM domains 1 0.46 Down AF220153 cell differentiation
synaptic vesicle glycoprotein 2A 0.461 Down NM_014849 transport
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)
0.464 Down Z97630 amino acid metabolism
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 ///
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
0.482 Down M22921 carbohydrate metabolism
7-dehydrocholesterol reductase 0.482 Down NM_001360 cholesterol biosynthesis
collagen, type VI, alpha 1 0.5 Down BE350145 cell adhesion
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
0.501 Down NM_003078 chromatin remodeling
actin-related protein 3-beta 0.505 Down NM_020445 actin filament polymerization
7-dehydrocholesterol reductase 0.515 Down AW150953 cholesterol biosynthesis
solute carrier family 22 (organic cation
transporter), member 17 0.518 Down NM_020372 tRNA aminoacylation for
protein translation
kinesin family member 13B 0.526 Down NM_015254 T-cell activation
general transcription factor IIF, polypeptide 1, 74kDa
0.53 Down BC000120 positive regulation of
transcription
four and a half LIM domains 1 0.54 Down AF063002 cell differentiation
BCL2-associated X protein 0.551 Down NM_004324 apoptosis
midkine (neurite growth-promoting factor 2)
0.553 Down M69148 cell differentiation
--- 0.554 Down AI796813 ---
microfibrillar-associated protein 2 0.558 Down NM_017459 ---
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
0.561 Down N33167 G1 phase of mitotic cell cycle
v-rel reticuloendotheliosis viral
oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)
0.562 Down NM_006509 regulation of transcription,
DNA-dependent
glucose-6-phosphate dehydrogenase 0.582 Down NM_000402 carbohydrate metabolism
tripartite motif-containing 16 0.583 Down NM_006470 ---
nth endonuclease III-like 1 (E. coli) 0.585 Down U79718 base-excision repair
discoidin domain receptor family, member 1
0.592 Down U48705 cell adhesion
tropomyosin 2 (beta) 0.592 Down AL566786 muscle development
aldehyde dehydrogenase 4 family, member A1
0.592 Down U24267 metabolism
caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2)
0.593 Down U13022 apoptotic program
translocation protein 1 1.492 Up U93239 cotranslational
protein-membrane targeting RAB guanine nucleotide exchange
factor (GEF) 1
1.495 Up NM_014504 endocytosis
cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1
1.504 Up NM_012124
sperm associated antigen 9 1.505 Up AB011088 spermatogenesis
tumor necrosis factor receptor superfamily, member 6
1.531 Up NM_000043 anti-apoptosis
Transmembrane protein 1 1.537 Up AI922538 sodium ion transport
fibronectin type III domain containing 3 1.538 Up NM_014923 ---
dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2)
1.55 Up NM_001935 immune response
olfactomedin 1 1.633 Up NM_006334 7275 // development // inferred
from electronic annotation ///
7399 // neurogenesis //
traceable author statement restin (Reed-Steinberg cell-expressed
intermediate filament-associated protein)
1.636 Up NM_002956 ---
dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2)
1.665 Up M74777 immune response
matrix metalloproteinase 10 (stromelysin 2)
1.669 Up NM_002425 collagen catabolism
heterogeneous nuclear
ribonucleoprotein R 1.679 Up NM_005826 mRNA processing
decay accelerating factor for complement (CD55, Cromer blood group system)
1.701 Up NM_000574 complement activation, classical
pathway Janus kinase 2 (a protein tyrosine
kinase)
1.708 Up AF001362 JAK-STAT cascade
glycine receptor, beta 1.716 Up AF094754 cell surface receptor linked
signal transduction
UDP-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
1.754 Up NM_003774 ---
Phospholipase C, epsilon 1 1.79 Up NM_016341 Ras protein signal transduction
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
1.798 Up NM_006379 cell growth and/or maintenance
dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2)
1.806 Up NM_001935 immune response
interleukin 13 receptor, alpha 2 1.808 Up NM_000640 ---
Alstrom syndrome 1 1.829 Up AI825212 ---
stromal antigen 3 1.833 Up NM_012447 cell cycle
leucine rich repeat containing 2 1.871 Up NM_024512 ---
ATPase family, AAA domain
containing 2 1.899 Up NM_014109 ---
downregulated in ovarian cancer 1 1.946 Up NM_014890 ---
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
1.992 Up AI962897 cell growth and/or maintenance
SAR1a gene homolog 1 (S. cerevisiae) 2.213 Up AY008268 ER to Golgi transport
olfactomedin 1 2.217 Up R38389 development
cell cycle progression 1 2.23 Up NM_004748 ---
MLF1 interacting protein 2.234 Up NM_024629 ---
SAR1a gene homolog 1 (S. cerevisiae) 2.588 Up BC003658 ER to Golgi transport
CD36 antigen (collagen type I receptor, thrombospondin receptor)
2.704 Up NM_000072 blood coagulation
cyclic nucleotide gated channel alpha
3 3.752 Up NM_001298 ion transport
Tabelle 7.5: Vergleich der behandelten alten Fibroblasten mit behandelten jungen Fibroblasten Gene Title Ratio of medians (alt_b/jung_b) MW_altbvsjungb -
Mann-Whitney_Change Direction Representative Public ID Gene Ontology Biological Process
diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
0.2 Down M60278 muscle development
interleukin 1 receptor antagonist 0.29 Down AW083357 immune response
epidermal growth factor
(beta-urogastrone) 0.304 Down NM_001963 DNA replication
transcription elongation factor A (SII), 2
0.329 Down NM_003195 RNA elongation
fatty acid desaturase 2 0.342 Down NM_004265 fatty acid biosynthesis
tumor-associated calcium signal transducer 2
0.387 Down J04152 cell proliferation
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
0.399 Down NM_003078 chromatin remodeling
cullin 7 0.402 Down NM_014780 cell cycle
synaptic vesicle glycoprotein 2A 0.413 Down NM_014849 transport
myosin regulatory light chain
interacting protein 0.425 Down NM_013262 cell motility
four and a half LIM domains 1 0.46 Down AF098518 cell differentiation
four and a half LIM domains 1 0.465 Down U29538 cell differentiation
chromatin assembly factor 1,
subunit B (p60) 0.468 Down NM_005441 DNA repair
7-dehydrocholesterol reductase 0.47 Down NM_001360 cholesterol biosynthesis
cyclin-dependent kinase inhibitor
1C (p57, Kip2) 0.477 Down N33167 G1 phase of mitotic cell cycle
chromosome 6 open reading frame 108
0.488 Down NM_006443 cell proliferation
four and a half LIM domains 1 0.494 Down AF220153 cell differentiation
peroxiredoxin 2 /// peroxiredoxin
2 0.499 Down L19185 response to oxidative stress
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
0.528 Down BG034972 G-protein signaling
--- 0.534 Down NM_018678 ---
suppression of tumorigenicity 5 0.543 Down NM_005418 ---
four and a half LIM domains 1 0.551 Down AF063002 cell differentiation actin related protein 2/3 complex,
subunit 4, 20kDa 0.554 Down BE891920 actin filament polymerization //
inferred from electronic annotation
stearoyl-CoA desaturase
(delta-9-desaturase) 0.573 Down AA678241 fatty acid biosynthesis
serum response factor (c-fos serum response element-binding transcription factor)
0.583 Down NM_003131 regulation of transcription from
Pol II promoter phosphoinositide-3-kinase,
catalytic, delta polypeptide ///
phosphoinositide-3-kinase, catalytic, delta polypeptide
0.591 Down U86453 protein amino acid
phosphorylation
polymerase (RNA) I polypeptide C, 30kDa
0.594 Down NM_004875 transcription
cytochrome P450, family 1, subfamily B, polypeptide 1
1.971 Up AU144855 electron transport
chromosome 21 open reading frame 107
1.999 Up NM_018963 ---
SAR1a gene homolog 1 (S.
cerevisiae) 2.007 Up AY008268 ER to Golgi transport
retinoblastoma 1 (including osteosarcoma)
2.017 Up M19701 cell cycle checkpoint
kinectin 1 (kinesin receptor) ///
thioredoxin domain containing 7 (protein disulfide isomerase)
2.025 Up Z22551 electron transport
adaptor-related protein complex
4, epsilon 1 subunit 2.028 Up AB030653 endocytosis
cytochrome P450, family 1, subfamily B, polypeptide 1
2.056 Up AU154504 electron transport
eukaryotic translation initiation
factor 5B 2.07 Up NM_015904 protein biosynthesis
centrosome-associated protein 350
2.073 Up AA635523 ---
tripartite motif-containing 2 2.073 Up NM_015271 protein ubiquitination
hypothetical protein FLJ14345 2.163 Up NM_024733 regulation of transcription
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
2.175 Up U48722 cell proliferation
metallothionein 1K 2.184 Up R06655 ---
tissue factor pathway inhibitor 2 2.27 Up AL574096 blood coagulation sema domain, immunoglobulin
domain (Ig), short basic domain, secreted, (semaphorin) 3C
2.286 Up NM_006379 cell growth and/or maintenance
protein tyrosine phosphatase,
receptor type, D 2.294 Up NM_002839 phosphate metabolism
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
2.301 Up U95089 cell proliferation
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
2.309 Up AI962897 cell growth and/or maintenance
leucine rich repeat containing 2 2.466 Up NM_024512 ---
interleukin 1 receptor accessory protein
2.495 Up NM_002182 ---
SAR1a gene homolog 1 (S.
cerevisiae) 2.645 Up BC003658 ER to Golgi transport
Sarcoglycan, delta (35kDa dystrophin-associated
glycoprotein)
2.846 Up AA570453 cytoskeleton organization and
biogenesis splicing factor,
arginine/serine-rich 6
2.97 Up NM_006275 mRNA splice site selection