ALBINA, E., Y. LEFORBAN, T. BARON, J. P. PLANA DURAN u. P. VANNIER (1992):
An enzyme linked immunosorbent assay (ELISA) for the detection of antibodies to the porcine reproductive and respiratory syndrome (PRRS) virus.
Ann. Rech. Vet. 23: 167-176.
ALBINA, E., F. MADEC, R. CARIOLET u. J. TORRISON (1994):
Immune response and persistence of the porcine reproductive and respiratory syndrome virus in infected pigs and farm units.
Vet. Rec. 134: 567-573.
ALLENDE, R., T. L. LEWIS, Z. LU, D. L. ROCK, G. F. KUTISH, A. ALI, A. R. DOSTER u. F. A. OSORIO (1999):
North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions.
J. Gen. Virol. 80: 307-315.
ALLENDE, R., W. W. LAEGREID, G. F. KUTISH, J. A. GALEOTA, R. W. WILLS u. F. A.
OSORIO (2000):
Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection.
J. Virol. 74: 10834-10837.
ANDREYEV, V. G., R. D. WESLEY, W. L. MENGELING, A. C. VORWALD u. K. M.
LAGER (1997):
Genetic variation and phylogenetic relationships of 22 porcine reproductive and respiratory syndrome virus (PRRSV) field strains based on sequence analysis of open reading frame 5.
Arch. Virol. 142: 993-1001.
ANONYM (2006):
Erregerprävalenz von PRRSV in deutschen Schweinebeständen.
Anim Health Res. Rev. http\\www.animal-health.de, 20.12.2006 ANONYM (2007):
PRRSV-Erregerübertragung. http\\www.animal-health.de, 10. 08. 2007
BATISTA, L., C. PIJOAN, S. DEE, M. OLIN, T. MOLITOR, H. S. JOO, Z. XIAO u. M.
MURTAUGH (2004):
Virological and immunological responses to porcine reproductive and respiratory syndrome virus in a large population of gilts.
Can. J. Vet. Res. 68: 267-273.
BAUTISTA, E. M., GOYAL, S. M., YOON, I.J., JOO, H. S. u. COLLINS, J. E. (1993):
Comparison of porcine alveolar macrophages and CL 2621 for detection of porcine reproductive and respiratory syndrome (PRRS) virus and anti-PRRS antibody.
J. Vet. Diagn. Invest. 5: 163-165
BENFIELD, D. A., J.E.COLLINS, S.A. DEE, P.G. HALBUR, H.S. JOO, K.M. LAGER, W.L. MENGELING, M.P. MURTAUGH, K.D. ROSSOW, G.W. TEVENSON u. J.J.
ZIMMERMANN. (1999):
Porcine reproductive and respiratory syndrome.
In: Diseases of swine, Iowa State University Press, Ames Iowa, 8. Aufl., Blackwell, S. 201-232
BIEBRICHER, C. K., u. M. EIGEN (2006):
What is a quasispecies?
Curr. Top. Microbiol. Immunol. 299: 1-31.
BIERK, M. D., S. A. DEE, K. D. ROSSOW, S. OTAKE, J. E. COLLINS u. T. W. MOLITOR (2001):
Transmission of porcine reproductive and respiratory syndrome virus from persistently infected sows to contact controls.
Can. J. Vet. Res. 65: 261-266.
BILODEAU, R., D. ARCHAMBAULT, S. A. VEZINA, R. SAUVAGEAU, M. FOURNIER, u. S. DEA (1994):
Persistence of porcine reproductive and respiratory syndrome virus infection in a swine operation.
Can. J. Vet. Res. 58: 291-298.
BØTNER, A., J. NIELSEN u. V. BILLE-HANSEN (1994):
Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus.
Vet. Microbiol. 40: 351-360.
BØTNER, A., B. STRANDBYGAARD, K. J. SORENSEN, P. HAVE, K. G. MADSEN, E. S.
MADSEN u. S. ALEXANDERSEN (1997):
Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine.
Vet. Rec. 141: 497-499.
Literaturverzeichnis
BOUVET, J., C. CHARREYRE, V. LAMBERT u. C. AEBERLE (2001):
Genetic variability of European Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) isolates by RT-PCR and Restriction Fragment Lenght Polymorphism of ORF5 gene.
Revue Med. Vet. 152, 611-616.
CAFRUNY, W. A. und HOVINEN, D. E. (1988):
The relationship between route of infection and minimum infectious dose: Studies with lactate dehydrogenase-elevating virus
J. Virol. Methods, 20: 265-268
CANCEL-TIRADO, S. M., R. B. EVANS u. K. J. YOON (2004):
Monoclonal antibody analysis of porcine reproductive and respiratory syndrome virus epitopes associated with antibody-dependent enhancement and neutralization of virus infection.
Vet. Immunol. Immunopathol. 102: 249-262.
CANO, J. P., S. A. DEE, M. P. MURTAUGH u. C. PIJOAN (2007a):
Impact of a modified-live porcine reproductive and respiratory syndrome virus vaccine intervention on a population of pigs infected with a heterologous isolate.
Vaccine 25: 4382-4391.
CANO, J. P., S. A. DEE, M. P. MURTAUGH, C. A. TRINCADO u. C. B. PIJOAN (2007b):
Effect of vaccination with a modified-live porcine reproductive and respiratory syndrome virus vaccine on dynamics of homologous viral infection in pigs.
Am. J. Vet Res. 68: 565-571.
CARMAN, S., S. E. SANFORD u. S. DEA (1995):
Assessment of seropositivity to porcine reproductive and respiratory syndrome (PRRS) virus in swine herds in Ontario--1978 to 1982.
Can. Vet. J. 36: 776-777.
CAVANAGH, D. (1997):
Nidovirales: a new order comprising Coronaviridae and Arteriviridae.
Arch. Virol. 142: 629-633.
CAVANAGH, D., D. A. BRIAN, M. A. BRINTON, L. ENJUANES, K. V. HOLMES, M. C.
HORZINEK, M. M. LAI, H. LAUDE, P. G. PLAGEMANN u. S. G. SIDDELL (1993):
The Coronaviridae now comprises two genera, coronavirus and torovirus: Report of the coronaviridae study group.
Adv. Exp. Med. Biol. 342: 255-257.
CHA, S. H., C. C. CHANG u. K. J. YOON (2004):
Instability of the restriction fragment length polymorphism pattern of open reading frame 5 of porcine reproductive and respiratory syndrome virus during sequential pig-to-pig passages.
CHANG, C. C., K. J. YOON, J. J. ZIMMERMAN, K. M. HARMON, P. M. DIXON, C. M.
DVORAK u. M. P. MURTAUGH (2002):
Evolution of porcine reproductive and respiratory syndrome virus during sequential passages in pigs.
J. Virol. 76: 4750-4763.
CHO, H. J., D. DEREGT u. H. S. JOO (1996):
An ELISA for porcine reproductive and respiratory syndrome: production of antigen of high quality.
Can. J. Vet. Res. 60: 89-93.
CHOMCZYNSKI, P. u. K. SACCHI (1987):
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
Anal. Biochem, 162: 156-159.
CHRISTOPHER-HENNINGS, J., E. A. NELSON, R. J. HINES, J. K. NELSON, S. L.
SWENSON, J. J. ZIMMERMAN, C. L. CHASE, M. J. YAEGER u. D. A. BENFIELD (1995a):
Persistence of porcine reproductive and respiratory syndrome virus in serum and semen of adult boars.
J. Vet. Diagn. Invest, 7: 456-464.
CHRISTOPHER-HENNINGS, J., E. A. NELSON, J. K. NELSON, R. J. HINES, S. L.
SWENSON, H. T. HILL, J. J. ZIMMERMAN, J. B. KATZ, M. J. YAEGER, u. C. C.
CHASE, (1995b):
Detection of porcine reproductive and respiratory syndrome virus in boar semen by PCR.
J. Clin. Microbiol. 33: 1730-1734.
CHRISTOPHER-HENNINGS, J., E. A. NELSON, J. K. NELSON u. D. A. BENFIELD (1997):
Effects of a modified-live virus vaccine against porcine reproductive and respiratory syndrome in boars.
Am. J. Vet. Res. 58: 40-45.
CHRISTOPHER-HENNINGS, J., E. A. NELSON, J. K. NELSON, K. D. ROSSOW, J. L.
SHIVERS, M. J. YAEGER, C. C. CHASE, R. A. GARDUNO, J. E. COLLINS u. D. A.
BENFIELD (1998):
Identification of porcine reproductive and respiratory syndrome virus in semen and tissues from vasectomized and nonvasectomized boars.
Vet. Pathol. 35: 260-267.
Literaturverzeichnis
CHRISTOPHER-HENNINGS, J., L. D. HOLLER, D. A. BENFIELD, u. E. A. NELSON (2001):
Detection and duration of porcine reproductive and respiratory syndrome virus in semen, serum, peripheral blood mononuclear cells, and tissues from Yorkshire, Hampshire, and Landrace boars.
J. Vet. Diagn. Invest 13: 133-142.
CHRISTOPHER-HENNINGS, J., M. DAMMEN, E. NELSON, R. ROWLAND u. R.
OBERST (2006):
Comparison of RNA extraction methods for the detection of porcine reproductive and respiratory syndrome virus from boar semen.
J. Virol. Methods, 136: 248-253
COLLINS, J., R. FRANK u. K. ROSSOW (1998):
Swine diagnostic pathology
25th A. D. Leman Swine Conference, St. Paul, S: 1-9
CONZELMANN, K. K., N. VISSER, P. VAN WOENSEL u. H. J. THIEL (1993):
Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group.
Virology 193: 329-339.
CORBELLINI, L. G., H. SCHWERMER, P. PRESI, B. THUR, K. D. STARK u. M. REIST (2006):
Analysis of national serological surveys for the documentation of freedom from porcine reproductive and respiratory syndrome in Switzerland.
Vet. Microbiol. 118: 267-273.
COWLEY, J. A., L. C. CADOGAN, K. M. SPANN, N. SITTIDILOKRATNA u. P. J.
WALKER (2004):
The gene encoding the nucleocapsid protein of gill-associated nidovirus of Penaeus monodon prawns is located upstream of the glycoprotein gene.
J. Virol. 78: 8935-8941.
DEA, S., R. BILODEAU, R. ATHANASEOUS, R. A. SAUVAGEAU u. G. P.
MARTINEAU (1992):
PRRS syndrome in Quebec: isolation of a virus serologically related to Lelystad virus.
Vet. Rec. 130: 167-173
DEA, S., C. A. GAGNON, H. MARDASSI u. G. MILANE (1996):
Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein.
J. Clin. Microbiol. 34: 1488-1493.
DEA, S., C. A. GAGNON, H. MARDASSI, B. PIRZADEH u. D. ROGAN (2000):
Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates.
Arch. Virol. 145: 659-688.
DEE, S. A., u. H. JOO (1997):
Strategies to control PRRS: a summary of field and research experiences.
Vet. Microbiol. 55: 347-353.
DEE, S. A., M. TORREMORELL, K. ROSSOW, C. MAHLUM, S. OTAKE u. K.
FAABERG (2001):
Identification of genetically diverse sequences (ORF 5) of porcine reproductive and respiratory syndrome virus in a swine herd.
Can. J. Vet. Res. 65: 254-260.
DEE, S., J. DEEN, K. ROSSOW, C. WIESE, S. OTAKE, H. S. JOO u. C. PIJOAN (2002):
Mechanical transmission of porcine reproductive and respiratory syndrome virus throughout a coordinated sequence of events during cold weather.
Can. J. Vet. Res. 66: 232-239.
DELPUTTE, P. L., u. H. J. NAUWYNCK (2004):
Porcine arterivirus infection of alveolar macrophages is mediated by sialic acid on the virus.
J. Virol. 78: 8094-8101.
DEN BOON, J. A., K. S. FAABERG, J. J. MEULENBERG, A. L. WASSENAAR, P. G.
PLAGEMANN, A. E. GORBALENYA u. E. J. SNIJDER (1995):
Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein:
identification of two papainlike cysteine proteases.
J. Virol. 69: 4500-4505.
DESROSIERS, R. (2005):
Aerosol transmission of swine pathogens: overview of subject and evaluation of suspected field cases.
36th Ann. Meeting Am. Assoc. Swine Pract., Toronto, 2005, S. 405-416
DIAZ, I., L. DARWICH, G. PAPPATERRA, J. PUJOLS u. E. MATEU (2006):
Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs.
Virology 351: 249-259.
DOMINGO, E., C. ESCARMIS, N. SEVILLA u. E. BARANOWSKI (1998):
Population dynamics in the evolution of RNA viruses.
Adv. Exp. Med. Biol. 440: 721-727.
Literaturverzeichnis
DOMINGO, E., C. ESCARMIS, N. SEVILLA, A. MOYA, S. F. ELENA, J. QUER, I. S.
NOVELLA u. J. J. HOLLAND (1996):
Basic concepts in RNA virus evolution.
Fed. Am. Soc. Exper Biol.. 10: 859-864.
DOMINGO, E., u. J. J. HOLLAND (1997):
RNA virus mutations and fitness for survival.
Ann. Rev. Microbiol. 51: 151-178.
DONE, S. H., u. D. J. PATON (1995):
Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppression.
Vet. Rec. 136: 32-35.
DREW, T. W., J. J. MEULENBERG, J. J. SANDS u. D. J. PATON (1995):
Production, characterization and reactivity of monoclonal antibodies to porcine reproductive and respiratory syndrome virus.
J. Gen. Virol. 76: 1361-1369.
DREW, T. W., J. P. LOWINGS u. F. YAPP (1997):
Variation in open reading frames 3, 4 and 7 among porcine reproductive and respiratory syndrome virus isolates in the UK.
Vet. Microbiol. 55: 209-221.
EFRON, B. (1979):
Bootstrap Methods: Another look at the Jackknife.
Ann. Stat. 7 1: 1-26.
EFRON, B., E. HALLORAN, u. S. HOLMES (1996):
Bootstrap confidence levels for phylogenetic trees.
Proc. Natl. Acad. Science. 93: 13429-13434.
EGLI, C., B. THUR, L. LIU u. M. A. HOFMANN (2001):
Quantitative TaqMan RT-PCR for the detection and differentiation of European and North American strains of porcine reproductive and respiratory syndrome virus.
J. Virol. Methods 98: 63-75.
ELVANDER, M., B. LARSSON, A. ENGVALL, B. KLINGEBORN u. A. GUNNARSSON (1997):
Nation-wide survey of TGE/PRCV, CSF, PRRS, SVD, L. pomona and B. suis in pigs in Sweden.
Epidemiol. Sante Anim. 39: 31-32.
FAABERG, K. S., C. EVEN, G. A. PALMER u. P. G. PLAGEMANN (1995):
Disulfide bonds between two envelope proteins of lactate dehydrogenase-elevating virus are essential for viral infectivity.
J. Virol. 69: 613-617.
FEINBERG, A. P., u. B. VOGELSTEIN (1983):
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
Anal. Biochem. 132: 6-13.
FELSENSTEIN, J. (1989):
Phylip – phylogenetic interference package (version 3.2).
Cladistics 5: 164-166 FELSENSTEIN, J. (1992):
Estimating effective population size from samples of sequences: a bootstrap Monte Carlo integration method.
Genet. Res. 60: 209-220.
FENG, W.H., M.B. MC CAW, T. BROWN, J.XU, M. TOMPKINS, S. LASTER, C.
ALTIER u. D. BENFIELD (1998):
Lesions and clinical effects observed after in utero infection with PRRSV.
In: 15th Congr. Int. Pig Vet. Soc., Birmingham, Proc., S. 133
FENG, W.H., M.B. TOMPKINS, J.S. XU, T.T. BROWN, S.M. LASTER, H.X.
ZHANG u. M.B. McCAW (2002):
Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus.
Virology 302, 363-372
FERRIN, N. H., Y. FANG, C. R. JOHNSON, M. P. MURTAUGH, D. D. POLSON, M.
TORREMORELL, M. L. GRAMER u. E. A. NELSON (2004):
Validation of a blocking enzyme-linked immunosorbent assay for detection of antibodies against porcine reproductive and respiratory syndrome virus.
Clin. Diagn. Lab. Immunol. 11: 503-514.
FORSBERG, R. (2005):
Divergence time of porcine reproductive and respiratory syndrome virus subtypes.
Mol. Biol. Evol. 22: 2131-2134.
FORSBERG, R., M. B. OLEKSIEWICZ, A. M. PETERSEN, J. HEIN, A. BØTNER u. T.
STORGAARD (2001):
A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease.
Virology 289: 174-179.
Literaturverzeichnis
FORSBERG, R., T. STORGAARD, H. S. NIELSEN, M. B. OLEKSIEWICZ, P. CORDIOLI, G. SALA, J. HEIN u. A. BØTNER (2002):
The genetic diversity of European type PRRSV is similar to that of the North American type but is geographically skewed within Europe.
Virology 299: 38-47.
FROHMAN, M. A., M. K. DUSH u. G. R. MARTIN (1988):
Rapid production of full-lenght cDNAs from rare transcripts: Amplification using a single gene-spezific oligonucleotide primer.
Proc. Natl. Acad. Sci. U. S. A 85: 8998-9002.
GALINA, L., C. PIJOAN, M. SITJAR, W. T. CHRISTIANSON, K. ROSSOW u. J. E.
COLLINS (1994):
Interaction between Streptococcus suis serotype 2 and porcine reproductive and respiratory syndrome virus in specific pathogen-free piglets.
Vet. Rec. 134: 60-64.
GARNER, M. G., L. J. GLEESON, P. K. HOLYOAKE, R. M. CANNON u. W. J.
DOUGHTY (1997):
A national serological survey to verify Australia's freedom from porcine reproductive and respiratory syndrome.
Aust. Vet. J. 75: 596-600.
GEUE, A. (1995):
Untersuchungen zur Prävalenz und Inzidenz des Porcine Reproductive and Respiratory Syndrome (PRRS) in einem Kreis Schleswig-
Holsteins.
Diss., Freie Univ., Fachber. Veterinärmed., Berlin.
GILBERT, S. A., R. LAROCHELLE, R. MAGAR, H. J. CHO u. D. DEREGT (1997):
Typing of porcine reproductive and respiratory syndrome viruses by a multiplex PCR assay.
J. Clin. Microbiol. 35: 264-267.
GLOCK, X. T., u. G. BILKEI (2005):
The effect of postparturient urogenital diseases on the lifetime reproductive performance of sows.
Can. Vet J. 46: 1103-1107.
GOLDBERG, T. L., E. C. HAHN, R. M. WEIGEL u. G. SCHERBA (2000):
Genetic, geographical and temporal variation of porcine reproductive and respiratory syndrome virus in Illinois.
J. Gen. Virol. 81: 171-179.
GOLDBERG, T. L., J. F. LOWE, S. M. MILBURN u. L. D. FIRKINS (2003):
Quasispecies variation of porcine reproductive and respiratory syndrome virus during natural infection.
Virology 317: 197-207.
GONIN, P., H. MARDASSI, C. A. GAGNON, B. MASSIE u. S. DEA (1998):
A nonstructural and antigenic glycoprotein is encoded by ORF3 of the IAF-Klop strain of porcine reproductive and respiratory syndrome virus.
Arch. Virol. 143: 1927-1940.
GORELENKOV, V., A. ANTIPOV, S. LEJNINE, N. DARASELIA u. A. YURYEV (2001):
Set of novel tools for PCR primer design.
Biotechniques 31: 1326-1330.
GOYAL, S. (1993):
Porcine reproductive and respiratory syndrome.
Vet. Diagn. 5: 656-664.
GREISER-WILKE, I., S. DREIER, L. HAAS u. B. ZIMMERMANN (2006):
Genetische Typisierung des Virus der Klassischen Schweinepest Dtsch. Tierarztl. Wschr. 113: 134-138.
GROSSE BEILAGE, E., H. J. SALGE, H. KRABBE, u. Th. BLAHA (1991):
Untersuchungen zur Epidemiologie des Seuchenhaften Spätaborts der Zuchtsauen (PRRS) Prakt. Tierarzt, Collegium veterinarium XXII: S. 62-64.
GROSSE BEILAGE, E., u. Th. GROSSE BEILAGE (1993):
Epidemiologische Untersuchungen zum Verlauf des Reproduktionsgeschehens nach dem Seuchenhaften Spätabort (PRRS/PEARS) in Schweinezuchtbeständen.
Dtsch. Tierärztl. Wschr. 100: 32-36.
GROSSE BEILAGE, E. (1999):
Klinische und serologische Verlaufsuntersuchungen zu Prävalenz, Inzidenz und Interaktionen viraler und bakterieller Infektionen des Respirationstraktes von Mastschweinen.
Hannover, Tierärztl. Hochsch., Habil.-Schr GROSSE BEILAGE, E. (2002):
Internationale Erfahrungen mit der Bekämpfung des Porcine Reproductive and Respiratory Syndrome.
Tierärztl. Praxis 30: 153-163.
.
Literaturverzeichnis
HAAS, L. (1997):
Molecular epidemiology of animal virus diseases.
Zentralbl. Veterinärmed. B 44: 257-272.
HAESELER, A., u. D. LIEBERS. (2003):
Molekulare Evolution.
1. Aufl. Fischer Verlag, S. 25-31 ,
HALBUR, P. G., L. D. MILLER, P. S. PAUL, X. J. MENG, E. L. HUFFMAN u. J. J.
ANDREWS (1995):
Immunohistochemical identification of porcine reproductive and respiratory syndrome virus (PRRSV) antigen in the heart and lymphoid system of three-week-old colostrum-deprived pigs.
Vet. Pathol. 32: 200-204.
HALBUR, P. G., P. S. PAUL, X. J. MENG, M. A. LUM, J. J. ANDREWS u. J. A. RATHJE (1996):
Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig model.
J. Vet. Diagn. Invest. 8: 11-20.
HALL, T. A. (1999):
BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT.
Ser. 41: 95-98:
HANADA, K., Y. SUZUKI, T. NAKANE, O. HIROSE u. T. GOJOBORI (2005):
The origin and evolution of porcine reproductive and respiratory syndrome viruses.
Mol. Biol. Evol. 11: 2131-2134
HIGGINS, D. G., J. D. THOMPSON u. T. J. GIBSON (1996):
Using CLUSTAL for multiple sequence alignments.
Methods Enzymol. 266: 383-402.
HILLIS, D. M. (1997):
Phylogenetic analysis.
Curr. Biol. 7: 129-131.
HIROSE, O., H. KUDO, u. S. YOSHISAWA (1995):
Prevalence of porcine reproductive and respiratory syndrome virus in Chiba prefecture.
Vet. Microbiol. 48: 650-653.
HORTER, D. C., R. M. POGRANICHNIY, C. C. CHANG, R. B. EVANS, K. J. YOON u. J.
J. ZIMMERMAN (2002):
Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infection.
Vet. Microbiol. 86: 213-228.
HOUBEN, S., P. CALLEBAUT u. M. B. PENSAERT (1995):
Comparative study of a blocking enzyme-linked immunosorbent assay and the immunoperoxidase monolayer assay for the detection of antibodies to the porcine reproductive and respiratory syndrome virus in pigs.
J. Virol. Methods 51: 125-128.
HUNGNES, O., T. O. JONASSEN, C. M. JONASSEN u. B. GRINDE (2000):
Molecular epidemiology of viral infections. How sequence information helps us understand the evolution and dissemination of viruses.
APMIS 108: 81-97.
HYNDMAN, D. L., u. M. MITSUHASHI (2003):
PCR primer design.
Methods Mol. Biol. 226: 81-88.
INDIK, S., F. SCHMOLL, W. SIPOS u. D. KLEIN (2005):
Genetic variability of PRRS virus in Austria: consequences for molecular diagnostics and viral quantification.
Vet. Microbiol. 107: 171-178.
KAMPKE, T., M. KIENINGER u. M. MECKLENBURG (2001):
Efficient primer design algorithms.
Bioinformatics 17: 214-225.
KANDATHIL, A. J., S. RAMALINGAM, R. KANNANGAI, S. DAVID u. G. SRIDHARAN (2005):
Molecular epidemiology of HIV.
Indian J. Med. Res. 121: 333-344.
KANG, S. Y., S. I. YUN, H. S. PARK, C. K. PARK, H. S. CHOI u. Y. M. LEE (2004):
Molecular characterization of PL97-1, the first Korean isolate of the porcine reproductive and respiratory syndrome virus.
Virus Res. 104: 165-179.
Literaturverzeichnis
KATZ, J. B., A. L. SHAFER, K. A. EERNISSE, J. G. LANDGRAF u. E. A. NELSON (1995):
Antigenic differences between European and American isolates of porcine reproductive and respiratory syndrome virus (PRRSV) are encoded by the carboxyterminal portion of viral open reading frame 3.
Vet. Microbiol. 44: 65-76.
KEFFABER, K. K. (1989):
Reproductive failure of unknown etiology.
1th Am. Assoc. Swine Pract., Proc.: 1-19.
KIM, H. S., J. KWANG, I. J. YOON, H. S. JOO u. M. L. FREY (1993):
Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line.
Arch. Virol. 133: 477-483.
KIM, J., H. K. CHUNG, u. C. CHAE (2003):
Association of porcine circovirus 2 with porcine respiratory disease complex.
Vet. J. 166: 251-256.
KNOOP, V., u. K. MUELLER (2006):
Gene und Stammbäume. Ein Handbuch zur molekularen Phylogenetik.
1. Aufl. Spektrum-Verlag, 2006, S. 41-72
KÜMMERLEN, D., M. RITZMANN, C. FISCHÄß, W. SCHMIDT u. K. HEINRITZI (2005):
Untersuchungen zur Wirksamkeit und Verträglichkeit einer PRRSV-Lebendvakine (Europäischer Stamm).
Tierärztl. Umsch. 60: 29-34.
LAGER, K. M., W. L. MENGELING, u. S. L. BROCKMEIER (1997):
Homologous challenge of porcine reproductive and respiratory syndrome virus immunity in pregnant swine.
Vet. Microbiol. 58: 113-125.
LAGER, K. M., W. L. MENGELING u. R. D. WESLEY (2003):
Strain predominance following exposure of vaccinated and naive pregnant gilts to multiple strains of porcine reproductive and respiratory syndrome virus.
Can. J. Vet. Res. 67: 121-127.
LAROCHELLE, R., S. D'ALLAIRE u. R. MAGAR (2003):
Molecular epidemiology of porcine reproductive and respiratory syndrome virus (PRRSV) in Quebec.
Virus Res. 96: 3-14.
LAROCHELLE, R., H. MARDASSI, S. DEA u. R. MAGAR (1996):
Detection of porcine reproductive and respiratory syndrome virus in cell cultures and formalin-fixed tissues by in situ hybridization using a digoxigenin-labeled probe.
J. Vet. Diagn. Invest 8: 3-10.
LE GALL, A., O. LEGEAY, H. BOURHY, C. ARNAULD, E. ALBINA u. A. JESTIN (1998):
Molecular variation in the nucleoprotein gene (ORF7) of the porcine reproductive and respiratory syndrome virus (PRRSV).
Virus Res. 54: 9-21.
LE POTIER, M. F., P. BLANQUEFORT, E. MORVAN u. E. ALBINA (1997):
Results of a control programme for the porcine reproductive and respiratory syndrome in the French 'Pays de la Loire' region.
Vet. Microbiol. 55: 355-360.
LEE, C., J. G. CALVERT, S. K. WELCH u. D. YOO (2005):
A DNA-launched reverse genetics system for porcine reproductive and respiratory syndrome virus reveals that homodimerization of the nucleocapsid protein is essential for virus infectivity.
Virology 331: 47-62.
LEE, S. M., S. K. SCHOMMER u. S. B. KLEIBOEKER (2004):
Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes.
Vet. Immunol. Immunopathol. 102: 217-231.
LI, W. H. (1997):
Molecular phylogenetics: methods.
In: Molecular Evolution. Sinauer Associates, Inc., Sunderland Massachussetts, USA, S. 99-147.
LINDHAUS, W., u. B. LINDHAUS (1991):
Rätselhafte Schweinekrankheit.
Prakt. Tierarzt 5: 423-425.
LOPEZ, O. J., u. F. A. OSORIO (2004):
Role of neutralizing antibodies in PRRSV protective immunity.
Vet. Immunol. Immunopathol. 102: 155-163.
LOPEZ, O. J., M. F. OLIVEIRA, G. E. ALVAREZ, B. J. KWON, A. DOSTER u. F. A.
OSORIO (2007):
Protection Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection through Passive Transfer of PRRSV-Neutralizing Antibodies is Dose-dependent.
Clin. Vaccine Immunol. 3: 269-275
Literaturverzeichnis
LOULA, T. (1991):
Mystery pig disease Agri-pract. 12: 23-24
LOWE, J. E., R. HUSMANN, L. D. FIRKINS, F. A. ZUCKERMANN u. T. L. GOLDBERG (2005):
Correlation of cell-mediated immunity against porcine reproductive and respiratory syndrome virus with protection against reproductive failure in sows during outbreaks of porcine reproductive and respiratory syndrome in commercial herds.
J. Am. Vet. Med. Assoc. 226: 1707-1711.
LUCIA, T., Jr., M. N. CORREA, J. C. DESCHAMPS, I. BIANCHI, M. A. DONIN, A. C.
MACHADO, W. MEINCKE u. J. E. MATHEUS (2002):
Risk factors for stillbirths in two swine farms in the south of Brazil.
Prev. Vet. Med. 53: 285-292.
LUDEWIG, B., S. EHL, U. KARRER, B. ODERMATT, H. HENGARTNER u. R. M.
ZINKERNAGEL (1998):
Dendritic cells efficiently induce protective antiviral immunity.
J. Virol. 72: 3812-3818.
MARDASSI, H., P. GONIN, C. A. GAGNON, B. MASSIE u. S. DEA (1998):
A subset of porcine reproductive and respiratory syndrome virus GP3 glycoprotein is released into the culture medium of cells as a non-virion-associated and membrane-free (soluble) form.
J. Virol. 72: 6298-6306.
MARDASSI, H., B. MASSIE u. S. DEA (1996):
Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus.
Virology 221: 98-112.
MARDASSI, H., S. MOUNIR u. S. DEA (1994):
Identification of major differences in the nucleocapsid protein genes of a Quebec strain and European strains of porcine reproductive and respiratory syndrome virus.
J. Gen. Virol. 75: 681-685.
MARDASSI, H., S. MOUNIR u. S. DEA (1995):
Molecular analysis of the ORFs 3 to 7 of porcine reproductive and respiratory syndrome virus, Quebec reference strain.
Arch. Virol. 140: 1405-1418.
MARTELLI, P., P. CORDIOLI, L. G. ALBORALI, S. GOZIO, E. DE ANGELIS, L.
FERRARI, G. LOMBARDI u. P. BORGHETTI (2007):
Protection and immune response in pigs intradermally vaccinated against porcine reproductive and respiratory syndrome (PRRS) and subsequently exposed to a heterologous European (Italian cluster) field strain.
Vaccine 17: 3400-3408
MATEU, E., MARTIN, M. u. VIDAL, D. (2003):
Genetic diversity and phylogenetic analysis of glycoprotein 5 of European-type porcine reproductive and respiratory virus strains in spain.
J. of Gen. Virol. 84: 529-534.
MATEU, E., I. DIAZ, L. DARWICH, J. CASAL, M. MARTIN u. J. PUJOLS (2006):
Evolution of ORF5 of Spanish porcine reproductive and respiratory syndrome virus strains from 1991 to 2005.
Virus Res. 115: 198-206.
MEIER, W. A., J. GALEOTA, F. A. OSORIO, R. J. HUSMANN, W. M. SCHNITZLEIN u.
F. A. ZUCKERMANN (2003):
Gradual development of the interferon-gamma response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination.
Virology 309: 18-31.
MEIER, W. A., J. WHEELER, R. J. HUSMANN, F. A. OSORIO u. F. A. ZUCKERMANN (2000):
Characteristics of the immune response of pigs to wildtype PRRS virus or to commercial available vaccines: an unconventional response.
33th Ann. Meeting Am. Assoc. Swine Pract., Proc., 2000, S. 415-418.
MELLMANN, I., u. RM. STEINMAN (2001):
Dendritic cells: specialized and regulated antigen processing machines.
Immunology 106: 255-258.
MENG, X. J. (2000):
Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development.
Vet. Microbiol. 74: 309-329.
MENG, X. J., P. S. PAUL, P. G. HALBUR u. M. A. LUM (1995):
Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe.
Arch. Virol. 140: 745-755.
Literaturverzeichnis
MENG, X. J., P. S. PAUL, P. G. HALBUR u. I. MOROZOV (1995a):
Sequence comparison of open reading frames 2 to 5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virus.
J. Gen. Virol. 76: 3181-3188.
MENG, X. J., P. S. PAUL, I. MOROZOV, u. P. G. HALBUR (1996b):
A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus.
J. Gen. Virol. 77: 1265-1270.
MENGELING, W. L. (2005):
The porcine reproductive and respiratory syndrome quandary. Part II: Vaccines and vaccination strategy.
J. Swine Health Prod. 13: 91-95.
MENGELING, W. L., K. M. LAGER u. A. C. VORWALD (1994):
Temporal characterization of transplacental infection of porcine fetuses with porcine reproductive and respiratory syndrome virus.
Am. J. Vet. Res. 55: 1391-1398.
MENGELING, W. L., K. M. LAGER u. A. C. VORWALD (1996):
An Overview on vaccination for porince reproductive and respiratory syndrome.
20th A. D. Leman Swine Conf., St. Paul, S.139-142.
MENGELING, W. L., K. M. LAGER u. A. C. VORWALD (1998):
Clinical effects of porcine reproductive and respiratory syndrome virus on pigs during the
Clinical effects of porcine reproductive and respiratory syndrome virus on pigs during the