A
50 150 250
cpm
20 40 60
cpm x 103 XS52 PPD Inhibitor Th2
+ - - +
- - + +
+ - - -
+ + + +
+ + - +
20 40 60 80
Ag-pulse Fix
XS52 PPD Inhibitor Th1
+ - - +
- - + +
+ - - -
+ + + +
+ + - +
Fix Ag-Pulse
50 150 250
cpm x 103 cpm
DC (-) Pepstatin DC (+) Pepstatin
10 20 30 40 50
300 600 1250 2500 5000
Numbers of DCs
cpm x 103
B
Trypsin-Digested PPD
20 40 60 80 100 120 20 40 60 80 100 120
cpm x103 XS52 Ag Inhibitor T cells
+ + + Th2 - + - Th2 + + - Th2 - + - Th1 + + + Th1 + + - Th1
C
Native PPD