AKIYAMA,M.(2010): ABCA12 mutations and autosomal recessive congenital ichthyo-sis. A review of genotype/phenotype correlations and of pathogenetic concepts. Hu-man Mutation 31 (10), 1090–1096.
AKIYAMA,M.(2011): Updated molecular genetics and pathogenesis of ichthyosis.
Nagoya Journal of Medical Sciences 73, 79–90.
ALHAIDARI,Z.,ORTONNE,J.-P.,PISANI,A.(1994): Congenital ichthyosis in two Cavalier King Charles Spaniel littermates. Veterinary Dermatology 5 (3), 117–121.
ANDRÉ,C.,GRALL,A.,GUAGUERE,É.,THOMAS,A.,GALIBERT,F.(2013): Modèles spon-tanés de maladies humaines chez le chien. Exemple des ichtyoses. Bulletin de l'Académie Nationale de Médecine 197 (6), 1225–1230.
AUGUST,J.R.,CHICKERING,W.R.,RIKIHISA,Y.(1988): Congenital ichthyosis in a dog:
Comparison with the human ichthyosiform dermatoses. Compendium on Continuing Education for the Practising Veterinarian 10 (1), 40–45.
BAKER,J.R.,WARD,W.R.(1985): Ichthyosis in domestic animals: a review of the lite-rature and a case report. British Veterinary Journal 141 (1), 1–8.
BARNETT,K.C.(2006): Congenital keratoconjunctivitis sicca and ichthyosiform derma-tosis in the cavalier King Charles spaniel. The Journal of Small Animal Practice 47 (9), 524–528.
BARNHART,K.F.,CREDILLE,K.M.,AMBRUS,A.,DUNSTAN,R.W.(2004): A heritable ke-ratinization defect of the superficial epidermis in norfolk terriers. Journal of Compara-tive Pathology 130 (4), 246–254.
BAUER,A.,WALUK,D.P.,GALICHET,A.,TIMM,K.,JAGANNATHAN,V.,SAYAR,B.S.,W
IE-NER,D.J.,DIETSCHI,E.,MÜLLER,E.J.,ROOSJE,P.,WELLE,M.M.,LEEB,T.(2017): A de novo variant in the ASPRV1 gene in a dog with ichthyosis. PLoS Genetics 13 (3), DOI: 10.1371/journal.pgen.1006651.
BEINEKE,A.M.,HEWICKER-TRAUTWEIN,M.,KLOPFFLEISCH,R.(2015): Degeneration, Regeneration, Reparation und Wachstumsstörungen. In: Allgemeine Pathologie für die Tiermedizin. Hg. v. Baumgärtner, W., Gruber, A.D., Enke Verlag, 77–117.
BYGUM,A.,WESTERMARK,P.,BRANDRUP,F.(2008): Ichthyosis prematurity syndrome.
A well-defined congenital ichthyosis subtype. Journal of the American Academy of Dermatology 59 (5), 71-74.
CADIERGUES,M.-C.,PATEL,A.,SHEARER,D.H.,FERMOR,R.,MIAH,S.,HENDRICKS,A.
(2008): Cornification defect in the golden retriever. Clinical, histopathological, ult-rastructural and genetic characterisation. Veterinary Dermatology 19 (3), 120–129.
CANDI,E.,SCHMIDT,R.,MELINO,G.(2005): The cornified envelope. A model of cell death in the skin. Nature Reviews Molecular Cell Biology 6 (4), 328–340.
CASAL,M.L.,WANG,P.,MAULDIN,E.A.,LIN,G.,HENTHORN,P.S.(2017): A defect in NIPAL4 is associated with autosomal recessive congenital ichthyosis in American Bulldogs. PloS one 12 (1), DOI: 10.1371/journal.pone.0170708.
CHITTICK,E.J.,OLIVRY,T.,DALLDORF,F.,WRIGHT,J.,DALE,B.A.,WOLFE,B.A.(2002):
Harlequin ichthyosis in two greater kudu (Tragelaphus strepsiceros). Veterinary Pa-thology 39 (6), 751–756.
CHO,J.-K.,SON,J.-M.,LEE,D.-S.,PARK,S.-J.,CHO,S.-W.,SHIN,S.T.(2007):
Harlequin ichthyosis in a HanWoo calf. Journal of Veterinary Medical Science 69 (5), 553–555.
CHO,K.H.,SHIM,S.H.,KIM,M.(2018): Clinical, biochemical, and genetic aspects of Sjögren-Larsson syndrome. Clinical Genetics 93 (4), 721–730.
CRAIGLOW,B.G.(2013): Ichthyosis in the newborn. Seminars in Perinatology 37 (1), 26–31.
CREDILLE,K.M.,BARNHART,K.F.,MINOR,J.S.,DUNSTAN,R.W.(2005): Mild recessive epidermolytic hyperkeratosis associated with a novel keratin 10 donor splice-site mu-tation in a family of Norfolk terrier dogs. The British Journal of Dermatology 153 (1), 51–58.
CREDILLE,K.M.,MINOR,J.S.,BARNHART,K.F.,LEE,E.,COX,M.L.,TUCKER,K.A.,D
IE-GEL,K.L.,VENTA,P.J.,HOHL,D.,HUBER,M.,DUNSTAN,R.W.(2009): Transglutamina-se 1-deficient recessive lamellar ichthyosis associated with a LINE-1 inTransglutamina-sertion in Jack Russell terrier dogs. The British Journal of Dermatology 161 (2), 265–272.
DALE,B.A.,RESING,K.A.,LONSDALE-ECCLES,J.D.(1985): Filaggrin. A keratin fila-ment associated protein. Annals of the New York Academy of Sciences 455 (1), 330–
342.
DEMERJIAN,M.,CRUMRINE,D.A.,MILSTONE,L.M.,WILLIAMS,M.L.,ELIAS,P.M.(2006):
Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome). The Journal of Investigative Dermatology 126 (9), 2032–2038.
DIOCIAIUTI,A.,ANGIONI,A.,PISANESCHI,E.,ALESI,V.,ZAMBRUNO,G.,NOVELLI,A.,EL HACHEM,M.(2018): X-linked ichthyosis: Clinical and molecular findings in 35 Italian patients. Experimental Dermatology, DOI: 10.1111/exd.13667.
DOCAMPO,M.J.,ZANNA,G.,FONDEVILA,D.,CABRERA,J.,LÓPEZ-IGLESIAS,C.,C
ARVAL-HO,A.,CERRATO,S.,FERRER,L.,BASSOLS,A.(2011): Increased HAS2-driven hyaluro-nic acid synthesis in Shar-Pei dogs with hereditary cutaneous hyaluronosis (mucino-sis). Veterinary Dermatology 22 (6), 535–545.
DOLIGER,S.,DELVERDIER,M.,MORÉ,J.,LONGEART,L.,RÉGNIER,A.,MAGNOL,J.P.
(1995): Histochemical study of cutaneous mucins in hypothyroid dogs. Veterinary Pathology 32 (6), 628–634.
ELIAS,P.M.(1983): Epidermal lipids, barrier function, and desquamation. The Journal of Investigative Dermatology 80 (1), 44–49.
ELIAS,P.M.,CRUMRINE,D.,RASSNER,U.,HACHEM,J.-P.,MENON,G.K.,MAN,W., CHOY,M.H.W.,LEYPOLDT,L.,FEINGOLD,K.R.,WILLIAMS,M.L.(2004): Basis for ab-normal desquamation and permeability barrier dysfunction in RXLI. The Journal of Investigative Dermatology 122 (2), 314–319.
ELIAS,P.M.,FRIEND,D.S.(1975): The permeability barrier in mammalian epidermis.
The Journal of Cell Biology 65 (1), 180–191.
ELIAS,P.M.,WILLIAMS,M.L.,HOLLERAN,W.M.,JIANG,Y.J.,SCHMUTH,M.(2008): Pa-thogenesis of permeability barrier abnormalities in the ichthyoses. Inherited disorders of lipid metabolism. Journal of Lipid Research 49 (4), 697–714.
FARHADI,R.,KAZEMI,S.H.(2013): Harlequin ichthyosis in a neonate born with as-sisted reproductive technology - A case report. Medical Journal of the Islamic Re-public of Iran 27 (4), 229–232.
FISCHER,J.(2009): Autosomal recessive congenital ichthyosis. The Journal of Inves-tigative Dermatology 129 (6), 1319–1321.
FORMAN,O.P.,PENDERIS,J.,HARTLEY,C.,HAYWARD,L.J.,RICKETTS,S.L.,MELLERSH, C.S.(2012): Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed. PLoS Genetics 8 (1), DOI: 10.1371/journal.pgen.1002462.
GERHARDS,N.M.,SAYAR,B.S.,ORIGGI,F.C.,GALICHET,A.,MÜLLER,E.J.,WELLE,M.
M.,WIENER,D.J.(2016): Stem Cell-Associated Marker Expression in Canine Hair Follicles. The Journal of Histochemistry and Cytochemistry 64 (3), 190–204.
GRALL,A.,GUAGUÈRE,E.,PLANCHAIS,S.,GROND,S.,BOURRAT,E.,HAUSSER,I.,HITTE, C.,LE GALLO,M.,DERBOIS,C.,KIM,G.-J.,LAGOUTTE,L.,DEGORCE-RUBIALES,F.,R
AD-NER,F.P.W.,THOMAS,A.,KÜRY,S.,BENSIGNOR,E.,FONTAINE,J.,PIN,D.,Z IMMER-MANN,R.,ZECHNER,R.,LATHROP,M.,GALIBERT,F.,ANDRÉ,C.,FISCHER,J.(2012):
PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retrie-ver dogs and humans. Nature Genetics 44 (2), 140–147.
GROSS,T.L.,IHRKE,P.J.,WALDNER,E.J.,AFFOLTER,V.K.(2008): Diseases with Ab-normal Cornification. In: Skin Diseases of the Dog and Cat. Hg. v. Gross, T. L., Ihrke, P. J., Waldner, E.J., Affolter, V. K., 2. Aufl., Blackwell Science Ltd, 161–198.
GUAGUERE,E.,BENSIGNOR,E.,KÜRY,S.,DEGORCE-RUBIALES,F.,MULLER,A.,HERBIN, L.,FONTAINE,J.,ANDRÉ,C.(2009): Clinical, histopathological and genetic data of icht-hyosis in the golden retriever. A prospective study. The Journal of Small Animal Prac-tice 50 (5), 227–235.
GUAGUERE,E.,BENSIGNOR,E.,MULLER,A.,DEGORCE-RUBIALES,F.,ANDRE,C.(2007):
Epidemiological, clinical, histopathological and ultrastructural aspects of ichthyosis in golden retrievers: a report of 50 cases. Veterinary Dermatology 18 (5), 382–383.
HABERMEHL,K.-H.(2005): Haut. In: Lehrbuch der Anatomie der Haustiere. Band III:
Kreislaufsystem, Haut und Hautorgane. Hg. v. Nickel, R., Schummer, A., Seiferle, E., 4. Aufl., Parey Verlag, Stuttgart.
HALL,J.A.,YAGER,J.(2004): Diagnostic dermatology. The Canadian Veterinary Journal 45 (10), 872-874.
HARDY,M.H.(1992): The secret life of the hair follicle. Trends in Genetics 8 (2), 55–
61.
HARTLEY,C.,BARNETT,K.C.,PETTITT,L.,FORMAN,O.P.,BLOTT,S.,MELLERSH,C.S.
(2012a): Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in Cava-lier King Charles spaniel dogs. Part II. Candidate gene study. Veterinary Ophthalmo-logy 15 (5), 327–332.
HARTLEY,C.,DONALDSON,D.,SMITH,K.C.,HENLEY,W.,LEWIS,T.W.,BLOTT,S.,M EL-LERSH,C.,BARNETT,K.C.(2012b): Congenital keratoconjunctivitis sicca and ichthyo-siform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I. Clinical signs, histopathology, and inheritance. Veterinary Ophthalmology 15 (5), 315–326.
HAZEN,P.G.,JEROMIN,A.,LESH,A.,LEWANDOWSKI,A.,DUNSTAN,R.W.,PETRELLI,M., DAVIS,B.,JAWORSKY,C.(2007): Familial ichthyosiform keratoderma in newly out-of-pouch Bennett's wallabies (Macropus rufogriseus) and report of two cases. Veterina-ry Dermatology 18 (1), 23–28.
HELMAN,R.G.,RAMES,D.S.,CHESTER,D.K.(1997): Ichthyosiform dermatosis in a Soft-Coated Wheaten Terrier. Veterinary Dermatology 8 (1), 53–58.
HOFFMANN,A.,METZGER,J.,WÖHLKE,A.,PETERS,M.,JUNGINGER,J.,MISCHKE,R., DISTL,O.,HEWICKER-TRAUTWEIN,M.(2016): Congenital ichthyosis in 14 Great Dane puppies with a new presentation. Veterinary Pathology 53 (3), 614–620.
HOHL,D.(1990): Cornified cell envelope. Dermatologica 180 (4), 201–211.
JAGANNATHAN,V.,BANNOEHR,J.,PLATTET,P.,HAUSWIRTH,R.,DRÖGEMÜLLER,C.,D RÖ-GEMÜLLER,M.,WIENER,D.J.,DOHERR,M.,OWCZAREK-LIPSKA,M.,GALICHET,A.,WELLE, M.M.,TENGVALL,K.,BERGVALL,K.,LOHI,H.,RÜFENACHT,S.,LINEK,M.,PARADIS,M., MÜLLER,E.J.,ROOSJE,P.,LEEB,T.(2013): A mutation in the SUV39H2 gene in La-brador Retrievers with hereditary nasal parakeratosis (HNPK) provides insights into the epigenetics of keratinocyte differentiation. PLoS Genetics 9 (10), DOI:
10.1371/journal.pgen.1003848.
JASMIN, P. (2006): Klinisches Handbuch der Dermatologie des Hundes, 2. Aufl., M. &
H. Schaper, Hannover.
JENKINSON,D.M.(1990): Sweat and sebaceous glands and their function in domestic animals. In: Advances in Veterinary Dermatology, Vol. 1. Hg. v. Tscharner, C. von, Halliwell, R. E. W., Bailliere Tindall, 229–251.
JIA,Z.,MOULSON,C.L.,PEI,Z.,MINER,J.H.,WATKINS,P.A.(2007): Fatty acid trans-port protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fib-roblasts. The Journal of Biological Chemistry 282 (28), 20573–20583.
KALININ,A.,MAREKOV,L.N.,STEINERT,P.M.(2001): Assembly of the epidermal corni-fied cell envelope. Journal of Cell Science 114 (17), 3069–3070.
KALININ,A.E.,KAJAVA,A.V.,STEINERT,P.M.(2002): Epithelial barrier function: as-sembly and structural features of the cornified cell envelope. BioEssays 24 (9), 789–
800.
KHNYKIN,D.,MINER,J.H.,JAHNSEN,F.(2011): Role of fatty acid transporters in epi-dermis. Implications for health and disease. Dermato-Endocrinology 3 (2), 53–61.
KLAR,J.,SCHWEIGER,M.,ZIMMERMAN,R.,ZECHNER,R.,LI,H.,TÖRMÄ,H.,VAHLQUIST, A.,BOUADJAR,B.,DAHL,N.,FISCHER,J.(2009): Mutations in the fatty acid transport protein 4 gene cause the ichthyosis prematurity syndrome. American Journal of Hu-man Genetics 85 (2), 248–253.
KWOCHKA,K.W.,SMEAK,D.D.(1990): The cellular defect in idiopathic seborrhoea of Cocker Spaniels. In: Advances in Veterinary Dermatology, Vol. 1. Hg. v. Tscharner, C. von, Halliwell, R. E. W., Bailliere Tindall, 265–277.
LEHMBECKER,A.,RITTINGHAUSEN,S.,ROHN,K.,BAUMGÄRTNER,W.,SCHAUDIEN,D.
(2014): Nanoparticles and pop-off technique for electron microscopy. A known tech-nique for a new purpose. Toxicologic Pathology 42 (6), 1041–1046.
LEWIS,D.T.,FORD,M.J.,KWOCHKA,K.W.(1998a): Characterization and management of a Jack Russell terrier with congenital ichthyosis. Veterinary Dermatology 9 (2), 111–118.
LEWIS,D.T.,MESSINGER,L.M.,GINN,P.E.,FORD,M.J.(1998b): A hereditary disorder of cornification and multiple congenital defects in five Rottweiler dogs. Veterinary Der-matology 9 (1), 61–72.
LIEBICH,H.-G.,REESE,S.,BUDRAS,K.-D.(2010): Allgemeine Körperdecke (Integumen-tum commune). In: Funktionelle Histologie der Haussäugetiere und Vögel. Lehrbuch und Farbatlas für Studium und Praxis. Hg. v. Liebich, H.-G., Budras, K.-D., 5. Aufl., Schattauer, Stuttgart, 345–368.
LIN,M.-H.,KHNYKIN,D.(2014): Fatty acid transporters in skin development, function and disease. Biochimica et Biophysica Acta 1841 (3), 362–368.
LOVELL,J.E.,GETTY,R.(1957): The hair follicle, epidermis, dermis, and skin glands of the dog. American Journal of Veterinary Research 18 (69), 873–885.
MAULDIN,E.A.(2013): Canine ichthyosis and related disorders of cornification. The Veterinary Clinics of North America. Small Animal Practice 43 (1), 89–97.
MAULDIN,E.A.,CREDILLE,K.M.,DUNSTAN,R.W.,CASAL,M.L.(2008): The clinical and morphologic features of nonepidermolytic ichthyosis in the golden retriever. Veterina-ry Pathology 45 (2), 174–180.
MAULDIN,E.A.,WANG,P.,EVANS,E.,CANTNER,C.A.,FERRACONE,J.D.,CREDILLE,K.
M.,CASAL,M.L.(2015): Autosomal recessive congenital ichthyosis in American Bull-dogs is associated with NIPAL4 (ICHTHYIN) deficiency. Veterinary Pathology 52 (4), 654–662.
MECKLENBURG,L.,HETZEL,U.,UEBERSCHÄR,S.(2000): Epidermolytic ichthyosis in a dog. Clinical, histopathological, immunohistochemical and ultrastructural findings.
Journal of Comparative Pathology 122 (4), 307–311.
MEDLEAU, L., HNILICA, K. A. (2007): Dermatologie in der Kleintierpraxis. Atlas und Therapiehandbuch, Urban & Fischer in Elsevier, München.
MESSENGER,A.G.(1993): The control of hair growth. An overview. The Journal of Investigative Dermatology 101 (1), 4–9.
METZGER,J.,DISTL,O.(2014): A study of Shar-Pei dogs refutes association of the 'meatmouth' duplication near HAS2 with Familial Shar-Pei Fever. Animal Genetics 45 (5), 763–764.
METZGER,J.,WÖHLKE,A.,MISCHKE,R.,HOFFMANN,A.,HEWICKER-TRAUTWEIN,M., KÜCH,E.-M.,NAIM,H.Y.,DISTL,O.(2015): A novel SLC27A4 splice acceptor site mu-tation in Great Danes with ichthyosis. PloS one 10 (10), DOI:
10.1371/journal.pone.0141514.
MOLTENI,L.,DARDANO,S.,PARMA,P.,POLLI,M.,GIOVANNI,A.M. de, SIRONI,G.,L ON-GERI,M.(2006): Ichthyosis in Chianina cattle. Veterinary Record 158 (12), 412–414.
MOULSON,C.L.,MARTIN,D.R.,LUGUS,J.J.,SCHAFFER,J.E.,LIND,A.C.,MINER,J.H.
(2003): Cloning of wrinkle-free, a previously uncharacterized mouse mutation,
re-veals crucial roles for fatty acid transport protein 4 in skin and hair development. Pro-ceedings of the National Academy of Sciences of the United States of America 100 (9), 5274–5279.
MULISCH, M., WELSCH, U. (2015): Romeis Mikroskopische Technik, 19. Auflage, Springer Spektrum, Berlin, Heidelberg.
MULLER,G.H.(1976): Ichthyosis in two dogs. Journal of the American Veterinary Me-dical Association 169 (12), 1313–1316.
MULLER, G. H., KIRK, R. W., SCOTT, D. W. (1993): Kleintier-Dermatologie, G. Fischer, Stuttgart.
MÜLLER,E.J.,GALICHET,A.,WIENER,D.,MARTI,E.,DRÖGEMÜLLER,C.,WELLE,M., ROOSJE,P.,LEEB,T.,SUTER,M.M.(2014): Keratinocyte biology and pathology. Vete-rinary Dermatology 25 (4), 236–238.
MÜLLER,E.J.,WILLIAMSON,L.,KOLLY,C.,SUTER,M.M.(2008): Outside-in signaling through integrins and cadherins. A central mechanism to control epidermal growth and differentiation? The Journal of Investigative Dermatology 128 (3), 501–516.
MÜNTENER,T.,DOHERR,M.G.,GUSCETTI,F.,SUTER,M.M.,WELLE,M.M.(2011): The canine hair cycle - a guide for the assessment of morphological and immunohisto-chemical criteria. Veterinary Dermatology 22 (5), 383–395.
NEUBERT,R.H.H.,WEPF,R.(2008): Das Stratum corneum. Struktur und Morphologie einer hoch effizienten Barriere. Dermatopharmazie Medicos 4, 21–28.
NIEMANN,C.(2009): Differentiation of the sebaceous gland. Dermato-Endocrinology 1 (2), 64–67.
NIEMANN,C.,HORSLEY,V.(2012): Development and homeostasis of the sebaceous gland. Seminars in Cell and Developmental Biology 23 (8), 928–936.
NISHIFUJI,K.,YOON,J.S.(2013): The stratum corneum. The rampart of the mammali-an body. Veterinary Dermatology 24 (1), 60-72.e15-6.
NOLI,C.(2013): Seborrhö beim Hund. Pathogenese, klinisches Bild und topische Therapie. Veterinärspiegel 22 (4), 155–160.
NOLI, C., SCARAMPELLA, F. (2014): Praktische Dermatologie bei Hund und Katze. Kli-nik - Diagnose - Therapie, 3., überarbeitete und erweiterte Auflage, Schlütersche, Hannover.
OJI,V.,TADINI,G.,AKIYAMA,M.,BLANCHET BARDON,C.,BODEMER,C.,BOURRAT,E., COUDIERE,P.,DIGIOVANNA,J.J.,ELIAS,P.,FISCHER,J.,FLECKMAN,P.,GINA,M.,H AR-PER,J.,HASHIMOTO,T.,HAUSSER,I.,HENNIES,H.C.,HOHL,D.,HOVNANIAN,A.,ISHIDA -YAMAMOTO,A.,JACYK,W.K.,LEACHMAN,S.,LEIGH,I.,MAZEREEUW-HAUTIER,J.,M ILS-TONE,L.,MORICE-PICARD,F.,PALLER,A.S.,RICHARD,G.,SCHMUTH,M.,SHIMIZU,H., SPRECHER,E., VAN STEENSEL,M.,TAÏEB,A.,TORO,J.R.,VABRES,P.,VAHLQUIST,A., WILLIAMS,M.,TRAUPE,H.(2010): Revised nomenclature and classification of inherited ichthyoses. Results of the First Ichthyosis Consensus Conference in Sorèze 2009.
Journal of the American Academy of Dermatology 63 (4), 607–641.
PIERARD,G.E.,GOFFIN,V.,HERMANNS-LE,T.,PIERARD-FRANCHIMONT,C.(2000): Cor-neocyte desquamation. International Journal of Molecular Medicine 6 (2), 217–221.
PSCHYREMBEL, W. (2014): Klinisches Wörterbuch, 266. Aufl., De Gruyter, Berlin, Bos-ton.
RIZZO,W.B.(2007): Sjögren-Larsson syndrome. Molecular genetics and biochemical pathogenesis of fatty aldehyde dehydrogenase deficiency. Molecular Genetics and Metabolism 90 (1), 1–9.
ROETHIG,A.,SCHILDT,K.J.M.,WELLE,M.M.,WILDERMUTH,B.E.,NEIGER,R.,THOM,N.
(2015): Is "milk crust" a transient form of golden retriever ichthyosis? Veterinary Der-matology 26 (4), 265-269.
SCHÄFER,H.,SPIETH,K.(1992): Fallbericht: Idiopathische Muzinose bei einem Shar-Pei. Kleintierpraxis 37 (1), 403–404.
SCHMUTH,M.,MARTINZ,V.,JANECKE,A.R.,FAUTH,C.,SCHOSSIG,A.,ZSCHOCKE,J., GRUBER,R.(2013): Inherited ichthyoses/generalized Mendelian disorders of cornifica-tion. European Journal of Human Genetics 21 (2), 123–133.
SCHMUTH,M.,ORTEGON,A.M.,MAO-QIANG,M.,ELIAS,P.M.,FEINGOLD,K.R.,STAHL, A.(2005): Differential expression of fatty acid transport proteins in epidermis and skin appendages. The Journal of Investigative Dermatology 125 (6), 1174–1181.
SCOTT,D.W.(1989): Congenital ichthyosis in a dog. Journal of Companion Animal Practice 19 (1), 7–11.
SCOTT,D.W.,MILLER,W.H.,GRIFFIN,C.E.R.(2013): Structure and function of the skin. In: Muller & Kirk's Small Animal Dermatology. Hg. v. Miller, W. H., Muller, G. H., 6. Aufl., Elsevier/Saunders, St. Louis, Mo, 913–1003.
SMITH,F.J.D.,IRVINE,A.D.,TERRON-KWIATKOWSKI,A.,SANDILANDS,A.,CAMPBELL,L.
E.,ZHAO,Y.,LIAO,H.,EVANS,A.T.,GOUDIE,D.R.,LEWIS-JONES,S.,ARSECULERATNE, G.,MUNRO,C.S.,SERGEANT,A.,O'REGAN,G.,BALE,S.J.,COMPTON,J.G.,DIG IOVAN-NA,J.J.,PRESLAND,R.B.,FLECKMAN,P.,MCLEAN,W.H.I.(2006): Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nature Genetics 38 (3), 337–342.
STAHL,A.(2004): A current review of fatty acid transport proteins (SLC27). European Journal of Physiology 447 (5), 722–727.
SUTER,M.M.,CRAMERI,F.M.,OLIVRY,T.,MUELLER,E.,TSCHARNER,C. V.,JENSEN,P.
J.(1997): Keratinocyte biology and pathology. Veterinary Dermatology 8 (2), 67–100.
SUTER,M.M.,PANTANO,D.M.,AUGUSTIN-VOSS,H.G.,VARVAYANIS,M.,CRAMERI,F.
M.,WILKINSON,J.E.(1990): Keratinocyte differentiation in the dog. In: Advances in Veterinary Dermatology, Vol. 1. Hg. v. Tscharner, C. von, Halliwell, R. E. W., Bailliere Tindall, 252–264.
SUTER,M.M.,SCHULZE,K.,BERGMAN,W.,WELLE,M.,ROOSJE,P.,MÜLLER,E.J.
(2009): The keratinocyte in epidermal renewal and defence. Veterinary Dermatology 20 (5-6), 515–532.
TAMAMOTO-MOCHIZUKI,C.,BANOVIC,F.,BIZIKOVA,P.,LAPRAIS,A.,LINDER,K.E.,O LIV-RY,T.(2016): Autosomal recessive congenital ichthyosis due to PNPLA1 mutation in a golden retriever-poodle cross-bred dog and the effect of topical therapy. Veterinary Dermatology 27 (4), 306-309.
THELEN,A.(2012): Leise rieselt der Schnee - Entstehung und Ursachen von Krusten und Schuppen (2012). In: Schuppen und Krusten. Klinisches Bild, Diagnostik, Er-krankungen und Therapien. Proceedings der 13. Jahrestagung der Deutschen Ge-sellschaft für Veterinärdermatologie. Düsseldorf, 01.-03.06.2012.
VON BOMHARD,D.,KRAFT,W.(1998): Idiopathische Mucinosis beim Chinesischen Shar-Pei. Epidemiologie, klinisches Bild, histopathologische Befunde und Behand-lung. Tierärztliche Praxis 26 (3), 189–196.
WALTER,J.H.(2001): Cytokeratins in the canine epidermis. Veterinary Dermatology 12 (2), 81–87.
WELLE,M.M.,WIENER,D.J.(2016): The hair follicle. A comparative review of canine hair follicle anatomy and physiology. Toxicologic Pathology 44 (4), 564–574.
WERTZ,P.(2018): Epidermal lamellar granules. Skin Pharmacology and Physiology 31 (5), 262–268.
WOHLSEIN,P.,BAUMGÄRTNER,W.,HEWICKER-TRAUTWEIN,M.(2015): Haut. In: Speziel-le Pathologie für die Tiermedizin. Hg. v. Baumgärtner, W., Gruber, A. D., 1. Aufl., En-ke, Stuttgart, 342–394.
ZANNA,G.,DOCAMPO,M.J.,FONDEVILA,D.,BARDAGÍ,M.,BASSOLS,A.,FERRER,L.
(2009): Hereditary cutaneous mucinosis in Shar-Pei dogs is associated with increa-sed hyaluronan synthase-2 mRNA transcription by cultured dermal fibroblasts. Vete-rinary Dermatology 20 (5-6), 377–382.
ZANNA,G.,FONDEVILA,D.,BARDAGÍ,M.,DOCAMPO,M.J.,BASSOLS,A.,FERRER,L.
(2008): Cutaneous mucinosis in Shar-Pei dogs is due to hyaluronic acid deposition and is associated with high levels of hyaluronic acid in serum. Veterinary Dermatolo-gy 19 (5), 314–318.
Danksagung
Ich möchte mich ganz herzlich bei allen bedanken, die zum Gelingen dieser Arbeit beigetragen haben.
Mein ausdrücklicher Dank gilt Frau Prof. Dr. Marion Hewicker-Trautwein für die freundliche Betreuung und Unterstützung bei der Anfertigung dieser Dissertation, die jederzeit gewährte Hilfsbereitschaft und Ansprechbarkeit bei Fragen zur Durchfüh-rung der pathomorphologischen Untersuchungen, die freundliche Zusammenarbeit sowie das stets zügige und kooperative Durchsehen und Korrigieren von Manuskrip-ten.
Herrn Prof. Dr. Ottmar Distl danke ich für die initiale Idee zur Erstellung dieser Arbeit und die freundliche wissenschaftliche Betreuung.
Frau Dr. Julia Metzger danke ich für die wissenschaftliche Unterstützung bei der Durchführung von genetischen Analysen, die Hilfsbereitschaft bei allen Fragen rund um die Genetik und die kollegiale Zusammenarbeit bei Publikationen.
Herrn Dr. Johannes Junginger danke ich für viele hilfreiche Ratschläge im Rahmen der Probenahme, dem Erstellen von Publikationen, der Arbeit im Labor und in der Sektionshalle sowie für die entsprechende freundliche Unterstützung und Hilfsbereit-schaft.
Außerdem möchte ich allen Kolleginnen und Kollegen der Arbeitsgruppe Immunpa-thologie, inklusive Orka, für die freundliche Aufnahme im Team bedanken.
Frau Kerstin Rohn danke ich herzlich für die Einführung in die Elektronenmikroskopie und die Unterstützung bei der Aufarbeitung und Untersuchung der Proben am ELMI.
Für die Hilfe bei labortechnischen Fragen und die freundliche Unterstützung bei der Umsetzung der routinemäßigen und besonderen histochemischen Färbemethoden danke ich allen Mitarbeiterinnen des Diagnostikabors am Institut für Pathologie.
Allen Kolleginnen und Kollegen des Instituts für Pathologie danke ich für die kollegia-le Zusammenarbeit in der Sektionshalkollegia-le und beim Mikroskopieren der Sektionsfälkollegia-le.
Besonderer Dank gilt zudem meiner Familie, meinen Freunden und meinen tieri-schen Begleitern für ihre bedingungslose Unterstützung, die Motivation und das mir entgegengebrachte Vertrauen bei der Anfertigung der Dissertation.
Verlag der DVG Service GmbH
Friedrichstraße 17 35392 Gießen Tel.: 0641 / 24466 Fax: 0641 / 25375 E-Mail: info@dvg.de Web: www.dvg.de