ABBAS A.K., MURPHY K.M., SHER A. (1996):
Functional diversity of helper T- lymphocytes.
Nature 383, 787-793 ABBAS A.K. (2010):
Defective sialic acid acetylesterase and autoimmunity.
Nature 466, 243-247
AGGARWAL S., RAO A. (1998):
Modulation of Chromatin structure regulates cytokin gene expression during T cell differentiation.
Immunity 9, 765-775
AGGRAWAL S., GHILARDI N., XIE M.H., DE SAUVAGE F.J., GURNEY A.L. (2003):
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17.
J. Biol. Chem. 278, 1910-1914
AKDIS C.A. u. SIMONS F.E. (2006):
Histamine receptors are hot in immunopharmacology.
Eur. J. Pharmacol. 533, 69-76
AKIRA S., TAKEDA K., KAISHO T. (2001):
Toll-like receptors: critical proteins linking innate and acquired immunity.
Nat. Immunol. 2, 675-680
ALEKSZA M., LUKACS A., ANTAL-SZALMAS P., HUNYADI J., SZEGEDI A. (2002):
Increased frequency of intracellular interleukin (IL)-13 and IL-10, but not IL-4, expressing CD4+ and CD8+ peripheral T cells of patients with atopic dermatitis.
Br. J. Dermatol. 147, 1135-1141
ALTARE F., DURANDY A., LAMMAS D., EMILE J.F., LAMHAMEDI S., LE DEIST F., DRYSDALE P., JOUANGUY E., DÖFFINGER R., BERNAUDIN F., JEPPSON O., GOLLOB J.A., MEINL E., SEGAL A.W., FISCHER A., KUMARARATNE D., CASANOVA J.L. (1998):
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency.
Science 280, 1432-1435
ARRANG J.M., GARBARG M., SCHWARTZ J.C. (1983):
Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor.
Nature 302, 832-837
ASARCH A., BARAK O., LOO D.S., GOTTLIEB A.B. (2008):
Th17 cells: a new therapeutic target in inflammatory dermatoses.
J. Dermatology Treat. 19, 318-326 ASH A.S. u. SCHILD H.O. (1966):
Receptors mediating some actions of histamine.
Br. J. Pharmacol. Chemother. 27, 427-439
ASTE-AMEZAGA M., MA X., SARTORI A., TRINCHIERI G. (1998):
Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.
J. Immunol. 160, 5936-5944 BACHERT C. (2002):
The role of histamine in allergic disease: re-appraisal of its inflammatory potential.
Allergy 57, 287-296
BACON C.M., MC VICAR D.W., ORTALDO J.R., REES R.C., O´SHEA J.J., JOHNSTON J.A. (1995a):
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL- 12.
J. Exp. Med. 181, 399-404
BACON C.M., PETRICOIN E.F., ORTALDO J.R., REES R.C., LARNER A.C., JOHNSTON J.A., O´SHEA J.J. (1995b):
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.
Proc. Natl. Acad. Sci. USA 92, 7307- 11
BÄUMER W., SEEGERS U., BRAUN M., TSCHERNIG T. u. KIETZMANN M. (2004):
TARC and RANTES, but not CTACK, are induced in two models of allergic contact dermatitis. Effects of cilomilast and diflorasone diacetate on T-cell-attracting chemokines.
Br. J. Dermatol. 151, 823-830
BAKKER R.A., TIMMERMAN H., LEURS R. (2002):
Histamine receptors: specific ligands, receptor biochemistry, and signal transduction.
Clin. Allergy Immunol. 17, 27-64
BANCHEREAU J. u. STEINMAN R.M. (1998):
Dendritic cells and the control of immunity.
Nature 392, 245-252
BANU Y. u. WATANABE T. (1999):
Augmentation of antigen receptor-mediated responses by histamine H1 receptor signaling.
J. Exp. Med. 189, 673-682
BARGER G. u. DALE H.H. (1910):
Chemikal structure and sympathomimetic action of amines.
J. Physiol. 41, 19-59
BATTEN M., LI J., YI S., KLJAVIN N.M., DANILENKO D.M., LUCAS S., LEE J., DE SAUVAGE F.J., GHILARDI N. (2006):
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells.
Nat. Immunol. 7, 929-936
BELL J., MCQUEEN D., REES J. (2004):
Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb/c mice.
Br. J. Pharmacol. 142, 374– 380
BENTLEY G.A. u. MARIUZZA R.A. (1996):
The structure of the T cell antigen receptor.
Annu. Rev. Immunol. 14, 563-590
BEST C.H., DALE H.H., DUDLEY H.W., THORPE W.V. (1927):
The nature of the vaso-dilator constituents of certain tissue extracts.
J. Physiol. 62, 397-417 BEVAN J.M. (2004):
Helping the CD8+ T-cell response.
Nature reviews Immunology 4, 595-602
BLACK J.W., DUNCAN W.A., DURANT C.J., GANELLIN C.R., PARSONS E.M. (1972):
Definition and antagonism of histamine H 2 -receptors.
Nature 236, 385-390
BRADFORD M.M. (1976):
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
Analytic. Biochem. 72, 248-254
BROMBACHER F., KASTELEIN R.A., ALBER G. (2003):
Novel IL-12 family members shed light on the orchestration of Th1 responses.
Trends Immunol. 24, 207- 212
BUTTMANN M. u. RIECKMANN P. (2007):
Interferon-beta 1b in multiple sclerosis.
Expert. Rev. Neurother. 7, 227-239
CANTOR H u. BOYSE EA (1975):
Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity.
J. Exp. Med. 141, 1390-1399
CARMONDY R.J., RUAN Q., LIOU H.C., CHEN Y.H. (2007):
Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells.
J. Immunol. 178, 186-191
CARON G., DELNESTE Y., ROELANDTS E., DUEZ C., BONEFOY J.Y., PESTEL J., JEANNIN P. (2001):
Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells.
J. Immunol. 167, 3682-3686
CASANOVA J.L. u. ABEL L. (2004):
The human model: a genetic dissection of immunity to infection in natural conditions.
Nat. Rev. Immunol. 4, 55-66
CASTELANI M.L., ANOGEIANAKI A., FELACO P., TONIATO E., DE LUTIIS M.A., SHAIK B., FULCHERI M., VECCHIET J., TETE S., SALINI V., THEOHARIDES T.C., CARAFFA A., ANTINOLFI P., FRYDAS I., CONTI P., CUCCURULLO C., CIAMPOLI C., CERULLI G., KEMPURAIJ D. (2010):
IL-35, an anti-inflammatory cytokine which expands CD4+CD25+ Treg cells.
J. Biol. Regul. Homeost. Agents 24, 131-135
CELLA M., SCHEIDEGGER D., PALMER-LEHMANN K., LANE P., LANZAVECCHIA A., ALBER G. (1996):
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
J. Exp. Med. 184, 747-752
CLARK R.A. u. FUHLBRIGGE R.C. (2009):
Immunology and skin disease: frontiers in cutaneous immunology.
J. Invest. Dermatol. 129, 1849-1851
CONNELLY W.M., SHENTON F.C., LETHBRIDGE N., LEURS R., WALDVOGEL H.J., FAULL R.L., LEES G., CHAZOT P.L. (2009):
The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS.
Br. J. Pharmacol. 157, 55–63
COOPER D., HALES J., CAMP R. (2004):
IgE-dependent acitivation of T cells by allergen in atopic dermatitis: pathophysiologic relevance.
J. Invest. Dermatol. 123, 1086-1091
COWDEN J.M., ZHANG M., DUNFORD P.J., THURMOND R.L. (2010):
The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.
J. Invest. Dermatol. 130, 1023-1033
CUA D.J., SHERLOCK J., CHEN Y., MURPHY C.A., JOYCE B., SEYMOUR B., LUCIAN L., TO W., KWAN S., CHURAKOVA T., ZURAMSKI S., WIEKOWSKI M., LIRA S.A., GORMAN D. (2003):
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.
Nature 421, 744-748
CUMBERBATCH M., DEARMAN R.J., GRIFFITHS C.E., KIMBER I. (2003):
Epidermal Langerhans cell migration and sensitisation to chemical allergens.
APMIS 111, 797-804
DALE H.H. u. LAIDLAW P.P. (1910):
The physiological action of beta-iminazolylethylamine.
J. Physiol. 41, 318-344
DE JONG R., ALTARE F., HAAGEN I.A., ELFERING D.G., BOER T., VAN BREDA VRIESMAN P.J., KABEL P.J., DRAAISMA J.M., VAN DISSEL J.T., KROON F.P., CASANOVA J.L., OTTENHOFF T.H. (1998):
Severe mycobacterial and Salmonella infections in interleukin- 12 receptor-deficient patients.
Science 280, 1435-1438
DEARMAN R.J. u. KIMBER I. (1991):
Differential stimulation of immune function by respiratory and contact chemical allergens.
Immunology 72, 563-570
DEARMAN R.J. u. KIMBER I. (2000):
Role of CD4(+) T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate.
Immunology 101, 442-451
DEL VALLE J. u. GANTZ I. (1997):
Novel insights into histamine H2 receptor biology.
Am. J. Physiol. 273, 987-996
DEMBIC Z., HAAS W., WEISS S., MC CUBREY J., KIEFER H., STEINMETZ M. (1986):
Transfer of specificity by murine alpha and beta T-cell receptor genes.
Nature 320, 232-238
DEVERGNE O., BIRKENBACH M., KIEFF E. (1997):
Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.
Proc. Natl. Acad. Sci. USA 94, 12041-12046 DIEBOLD S.S. (2009):
Activation of dendritic cells by toll-like receptors and C-type lectins.
Handb. Exp. Pharmacol. 188, 3-30
DIJKSTRA D., LEURS R., CHAZOT P., SHENTON F.C., STARK H., WERFEL T., GUTZMER R. (2007):
Histamine downregulates monocyte CCL2 production through the histamine H(4) receptor.
J. Allergy Clin. Immunol. 120, 300-307
DIJKSTRA D., STARK H., CHAZOT P.L., SHENTON F.C., LEURS R., WERFEL T., GUTZMER R. (2008):
Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor.
J. Invest. Dermatol. 128, 1696-1703
DIVEU C., MC GEACHY M., CUA D. (2008):
Cytokines that regulate autoimmunity.
J. Immunol. 20, 663-668
DUNFORD P., O’DONNELL N., RILEY J., WILLIAMS K., KARLSSON L., THURMOND R. (2006):
The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.
J. Immunol. 176, 7062–7070
DUNFORD P.J., WILLIAMS K.N., DESAI P.J., KARLSSON L., MC QUEEN D., THURMOND R.L. (2007):
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus.
J. Allergy. Clin. Immunol. 119, 176–183
EHLERS S., LEHMANN J., MOSSMANN H., ALBER G., HÖLSCHER C. (2005):
Interleukin-12p40 mediates transient protection against Mycobacterium avium infection in the absence of interleukin-12.
Immunobiology 210, 217-227
EHLING G., HECHT M., HEUSENER A., HUESLER J.,GAMER A.O., VAN LOVEREN H., MAURER T., RIECKE K., ULLMANN L., ULRICH P., VANDEBRIEL R., VOHR H.W. (2005):
An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round.
Toxicol. 212, 69-79
EISEN H., ORRIS L., BELMAN S. (1952):
Elicitation of delayed allergic skin reactions with haptens: the dependence of eliciation on hapten combination with protein.
J. Exp. Med. 95, 473-487
ELENKOV I.J., WEBSTER E., PAPANICOLAOU D.A., FLEISHER T.A., CHROUSOS G.P., WILDER R.L. (1998):
Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors.
J. Immunol. 161, 2586-2593
EYLES J.L., METCALF D., GRUSBY M.J., HILTON D.J., STARR R. (2002):
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.
J. Biol. Chem. 277, 43735-40
FOREMAN J.C., RISING T.J., WEBBER S.E. (1985):
A study of the histamine H2-receptor mediating relaxation of the parenchymal lung strip preparation of the guinea-pig.
Br. J. Pharmacol. 86, 465-473
FREY H.-H. u. LÖSCHER W. (2009):
Lehrbuch der Pharmakologie und Toxikologie für die Veterinärmedizin.
7. Auflage Enke, Stuttgart.
FUNG-LEUNG W.P., THURMOND R.L., LING P., KARLSSON L. (2004):
Histamine H4 receptor antagonists: the new antihistamines?
Curr. Opin. Investig. Drugs 5, 1174-1183
GAD S.C., DUNN B.J., DOBBS D.W., REILLY C., WALSH R.D. (1986):
Development and validation of an alternative dermal sensitization test: the mouse ear swelling test (MEST).
Toxicol. Appl. Pharmacol. 84, 93-114
GANTNER F., SAKAI K., TUSCHE M.W., CRUIKSHANK W.W., CENTER D.M., BACON B.K. (2002):
Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.
J. Pharmacol. Exp. Ther. 303, 300-307
GANTZ I., MUNZERT G., TASHIRO T., SCHAFFER M., WANG L., DELVALLE J., YAMADA T. (1991):
Molecular cloning of the human histamine H2 receptor.
Biochem. Biophys. Res. Commun. 178, 1386-1392
GATELY M.K., CARVAJAL D.M., CONNAUGHTON S.E., GILLESSEN S., WARRIER R.R., KOLINSKY K.D., WILKINSON V.L., DWYER C.M., HIGGINS G.F. Jr, PODLASKI F.J., FAHERTY D.A., FAMILLETTI P.C., STERN A.S., PRESKY D.H. (1996):
Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo.
Ann. N Y Acad. Sci. 795, 1-12
GATELY M.K., RENZETTI L.M., MAGRAM J., STERN A.S., ADORINI L., GUBLER U., PRESKY D.H. (1998):
The Interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune response.
Annu. Rev. Immunol. 16, 495-521
GBAHOU F., VINCENT L., HUMBERT-CLAUDE M., TARDIVEL-LACOMBE J., CHABRET C., ARRANG J.M. (2006):
Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.
Br. J. Pharmacol. 147, 744-754
GILLESSEN S., CARVAJAL D., LING P., PODALSKI F.J., STREMLO D.L., FAMILLETTI P.C., GUBLER U., PRESKY D.H., STERN A.S., GATELY M.K. (1995):
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist.
Eur. J. Immunol. 25, 200-206
GORIELY S., NEURATH M.F., GOLDMAN M. (2008):
How microorganisms tip the balance between interleukin-12 family members.
Nat. Rev. Immunol. 8, 81-86
GREWE M., BRUIJNZEEL-KOOMEN C.A., SCHÖPF E., THEPEN T., LANGEVELD-WILDSCHUT A.G., RUZICKA T., KRUTMAN J. (1998):
A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis.
Immunol. Today 19, 359-361
GRUMONT R., HOCHREIN H., O´KEEFFE M., GUGASYAN R., WHITE C., CAMINSCHI I., COOK W., GERONDAKIS S. (2001):
c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.
J. Exp. Med. 194, 1021-1032
GSCHWANDTNER M., BUNK H., KOETHER B., THURMOND R., KIETZMANN M., WERFEL T., BAEUMER W., GUTZMER R. (in revision):
Histamine H4 receptor stimulation downregulates IL-27 in antigen presenting cells.
Immunology
GUTERMUTH J., OLLERT M., RING J., BEHRENDT H., JAKOB T. (2004):
Mouse models of atopic eczema critically evaluated.
Int. Arch. Allergy Immunol. 135, 262-276
GUTZMER R., LANGER K., LISEWSKI M., MOMMERT S., RIECKBORN D., KAPP A., WERFEL T. (2002):
Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cells.
J. Allergy Clin. Immunol. 109, 524-531
GUTZMER R., MOMMERT S., GSCHWANDTNER M., ZWINGMANN K., STARK H., WERFEL T. (2009):
The histamine H4 receptor is functionally expressed on T(H)2 cells.
J. Allergy Clin. Immunol. 123, 619–625
GUTZMER R., DIESTEL C., MOMMERT S., KOTHER B., STARK H., WITTMANN M., WERFEL T. (2005):
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells.
J. Immunol. 174, 5224-5232 HAAS H. u. PANULA P. (2003):
The role of histamine and the tuberomamillary nucleus in the nervous system.
Nat. Rev. Neurosci. 4, 121-130
HAPPEL K.I., DUBIN P.J., ZHENG M., GHILARDI N., LOCKHART C., QUINTON L.J., ODDEN A.R., SHELLITA J.E., BAGBY G.J., NELSON S., KOLLS J.K. (2005):
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae.
J. Exp. Med. 202, 761-769
HILL S.J., GANELLIN C.R., TIMMERMAN H., SCHWARTZ J.C., SHANKLEY N.P., YOUNG J.M., SCHUNACK W., LEVI R., HAAS H.L. (1997):
International Union of Pharmacology. XIII. Classification of histamine receptors.
Pharmacol. Rev. 49, 253-278
HILLIER A. u. GRIFFIN C.E. (2001):
The ACVD task force on canine atopic dermatitis (I): incidence and prevalence.
Vet. Immunol. Immunopathol. 81, 147-151 HILLIER A. (2002):
Definitvely diagnosing atopic dermatitis in dogs.
Veterinary Medicine, 198-209
HOFSTRA C.L., DESAI P.J., THURMOND R.L., FUNG-LEUNG W.P. (2003):
Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells.
J. Pharmacol. Exp. Ther. 305, 1212-1221
HÖLSCHER C., ATKINSON R.A., ARENDSE B., BROWN N., MYBURGH E., ALBER G., BROMBACHER F. (2001):
A protective and agonistic function of IL-12p40 in mycobacterial infection.
J. Immunol. 167, 6957-6966 HÖLSCHER C. (2004):
The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases.
Med. Microbiol. Immunol. 193, 1-17
HÖLSCHER C., HOLSCHER A., RUCKERL D., YOSHIMOTO T., YOSHIDA H., MAK T.
(2005):
The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis.
J. Immunol. 174, 3534-3544
HOPKINS J.E., NAISBITT D.J., KITTERINGHAM N.R., DEARMAN R.J., KIMBER I., PARK B.K. (2005):
Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarization.
Chem. Res. Toxicol. 18, 375-381
HUE S., AHERN P., BUONOCORE S., KULLBERG M.C., CUA D.J., MCKENZIE B.S., POWRIE J., MALOY K.J. (2006):
Interleukin-23 drives innate and T cell-mediated intestinal inflammation.
J. Exp. Med. 203, 2473-2483 HUNTER C.A. (2005):
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions.
Nat. Rev. Immunol. 5, 521-531
IDZKO M., LA SALA A., FERRARI D., PANTHER E., HEROUY Y., DICHMANN S., MOCKENHAUPT M., DI VIRGILIO F., GIROLOMONI G., NORGAUER J. (2002):
Expression and function of histamine receptors in human monocyte-derived dendritic cells.
J. Allergy Clin. Immunol. 109, 839-846
JABLONOWSKI J.A., GRICE C.A., CHAI W., DVORAK C.A., VENABLE J.D., KWOK A.K., LY K.S., WIE J., BAKER S.M., DESAI P.J., JIANG W., WILSON S.J., THURMOND R.L., KARLSSON L., EDWARDS J.P., LOVENBERG T.W., CARRUTHERS N.I. (2003):
The first potent and selective non-imidazole human histamine H4 receptor antagonists.
J. Med. Chem. 46, 3957-3960
JANEWAY C.A., TRAVERS P., WALPORT M., SHLOMCHIK M. (2001):
Immunologie 5. Auflage.
Spektrum Akademischer Verlag, Gustav Fischer.
JIANG W., LIM H.D., ZHANG M., DESAI P., DAI H., COLLING P.M., LEURS R., THURMOND R.L. (2008):
Cloning and pharmacological characterization of the dog histamine H4 receptor.
Eur. J. Pharmacol. 592, 26-32
JUTEL M., WATANABE T., AKDIS M., BLASER K., AKDIS C.A. (2002):
Immune regulation by histamine.
Curr. Opin. Immunol. 14, 735-740
JUTEL M., BLASER K., AKDIS C.A. (2005):
Histamine in allergic inflammation and immune modulation.
Int. Arch. Allergy Immunol. 137, 82–92 KAGAMI S. (2011):
IL-23 and Th17 cells in infections and psoriasis.
Nihon Rinsho Meneki Gakkai Kaishi 34, 13-19
KAPP A. (1995):
Atopic dermatitis – the skin manifestation of atopy.
Clin. Exp. Allergy 25, 210-219 KAPSENBERG M.L. (2003):
Dendritic-cell control of pathogen-driven T-cell polarization.
Nature Reviews Immunology 3, 984-993
KELLY M.N., KOLLS J.K., HAPPEL K., SCHWARTZMAN J.D., SCHWARZENBERGER P., COMBE C., MORETTO M., KHAN I.A. (2005):
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection.
Infect. Immun. 73, 617-621
KHADER S.A., PARTIDA-SANCHEZ S., BELL G., JELLEY-GIBBS D.M., SWAIN S., PEARL J.E., GHILARDI N., DESAUVAGE F.J., LUND F.E., COOPER A.M. (2006):
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection.
J. Exp. Med. 203, 1805-1815
KIMURA A. u. KISHIMOTO T. (2010):
Th17 cells in inflammation.
Int. Immunopharmacol. 11, 319-322
KLEINSCHEK M.A., MULLER U., BRODIE S.J., STENZEL W., KOHLER G., BLUMENSCHEIN W.M., STRAUBINGER R.K., MC CLANAHAN T., KASTELEIN R.A., ALBER G. (2006):
IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL- 12.
J. Immunol. 176, 1098-1106
KOGA C., KABASHIMA K., SHIRAISHI N., KOBAYASHI M., TOKURA Y. (2008):
Possible pathogenic role of Th17 cells for atopic dermatitis.
J. Invest. Dermatol. 128, 2625–2630
KOHKA H., NISHIBORI M., IWAGAKI H., NAKAYA N., YOSHINO T., KOBASHI K., SAEKI K., TANAKA N., AKAGI T. (2000):
Histamine is a potent inducer of IL-18 and IFN-gamma in human peripheral blood mononuclear cells.
J. Immunol. 164, 6640-6646
KOLLS J.K. u. LINDEN A. (2004):
Interleukin-17 family members and inflammation.
Immunity. 21, 467-476
KRASTEVA M., KEHREN J., DUCLUZEAU M.T., SAYAG M., CACCIAPUOTI M., AKIBA H., DESCOTES J., NICOLAS J.F. (1999):
Contact dermatitis I. Pathophysiology of contact sensitivity.
Eur. J. Dermatol. 9, 65-77
KULLBERG M.C., JANKOVIC D., FENG C.G., HUE S., GORELICK R., MCKENZIE B.S., CUA D.J., POWRIE F., CHEEVER A.W., MALOY K.J., SHER A. (2006):
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.
J. Exp. Med. 203, 2485-2494
LANGRISH C.L., MCKENZIE B.S., WILSON N.J., DE WAAL MALEFTY R., KASTELEIN R.A., CUA D.J. (2004):
IL-12 and IL-23: master regulators of innate and adaptive immunity.
Immunol. Rev. 202, 96-105
LANGRISH C.L., CHEN Y., BLUMENSCHEIN W.M., MATTSON J., BASHMA B., SEDGWICK J.D., MCCLANAHAN T., KASTELEIN R.A., CUA D.J. (2005):
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.
J. Exp. Med. 201, 233-240
LEIBUNDGUT-LANDMANN S., GROSS O., ROBINSON M.J., OSORIO F., SLACK E.C., TSONI S.V., SCHWEIGHOFFER E., TYBULEWICZ V., BROWN G.D., RULAND J., REIS E SOUSA C. (2007):
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.
Nat. Immunol. 8, 630-638
LEONARD J.P., WALDBURGER K.E., GOLDMAN S.J. (1996):
Regulation of experimental autoimmune encephalomyelitis by interleukin-12.
Ann. NY Acad. Sci. 795, 216-226
LEUNG D.Y.M. (2000):
Atopic dermatitis: new insights and oppertunities for therapeutic intervention.
J. Allergy Clin. Immunol. 105, 860-876
LEUNG D.Y.M., BOGUNIEWICZ M., HOWELL M.D., NOMURA I., HAMID Q.A. (2004):
New insights into atopic dermatitis.
J. Clin. Invest. 113, 651-657
LEURS R., BAKKER R.A., TIMMERMAN H., DE ESCH I.J. (2005):
The histamine H3 receptor: from gene cloning to H3 receptor drugs.
Nat. Rev. Drug. Discov. 4, 107-120
LEURS R., CHAZOT P., SHENTON F., LIM H., DE ESCH I. (2009):
Molecular and biochemical pharmacology of the histamine H4 receptor.
Br. J. Pharmacol. 157, 14–23
LIANG S.C., TAN X.Y., LUXENBERG D.P., KARIM R., DUNUSSI-JOANNOPOULOS K., COLLINS M., FOUSER L.A. (2006):
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides.
J. Exp. Med. 203, 2271-2279
LIEBERMAN L.A., CARDILLO F., OWYANG A.M., RENNICK D.M., CUA D.J., KASTELEIN R.A., HUNTER C.A. (2004):
23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.
J. Immunol. 173, 1887-1893
LIM H.D., VAN RIJN R.M., LING P., BAKKER A.R., THURMOND R.L., LEURS R.
(2005):
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
J. Pharmacol. Exp. Ther. 314, 1310-1321
LIM H.D., SMITS R.A., BAKKER R.A., VAN DAM C.M., DE ESCH I.J., LEURS R.
(2006):
Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.
J. Med. Chem. 49, 6650-6651
LING P., NGO K., NGUYEN S., THURMOND R.L., EDWARDS J.P., KARLSSON L., FUNG-LEUNG W.P. (2004):
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.
Br. J. Pharmacol. 142, 161-171
LIU C., WILSON S., KUEI C., LOVENBERG T.W. (2001a):
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
J. Pharmacol. Exp. Ther. 299, 121–130
LIU C., MA X., JIANG X., WILSON S.J., HOFSTRA C.L., BLEVITT J., PYATI J., LI X., CHAI W., CARRUTHERS N., LOVENBERG T.W. (2001b):
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
Mol. Pharmacol. 59, 420-426 LIU J., GUAN X., MA X. (2007):
Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways.
J. Exp. Med. 204, 141-152
LIU H., ALTENBACH R.J., CARR T.L., CHANDRAN P., HSIEH G.C., LEWIS L.G., MANELLI A.M., MILICIC I., MARSH K.C., MILLER T.R., STRAKHOVA M.I., VORTHERMS T.A., WAKEFIELD B.D., WETTER J.M., WITTE D.G., HONORE P., ESBENSHADE T.A., BRIONI J.D., COWART M.D. (2008):
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), A new histamine H4R antagonist that blocks pain responses against
carrageenan-induced hyperalgesia.
J. Med. Chem. 51, 7094-7098
LOVENBERG T.W., ROLAND B.L., WILSON S.J., JIANG X., PYATI J., HUVAR A., JACKSON M.R., ERLANDER M.G. (1999):
Cloning and functional expression of the human histamine H3-receptor.
Mol. Pharmacol. 55, 1101-1107
LOVENBERG T.W., PYATI J., CHANG H., WILSON S.J., ERLANDER M.G. (2000):
Cloning of rat histamine H3 receptor reveals distinct species pharmacological profiles.
J. Pharmacol. Exp. Ther. 293, 771-778
LUCAS S., GHILARDI N., LI J., DE SAUVAGE F.J. (2003):
IL27 regulates IL12 responsiveness of naive CD4+ T cells through Stat1dependent and -independent mechanisms.
Proc. Natl. Acad. Sci. U S A 100, 15047-15052 LUTTRELL L.M., GESTY-PALMER D. (2010):
Beyond desensitization: Physiological relevance of arrestin-mediated signaling.
Pharmacol. Rev. 62, 305-330
LUTZ M.B., KUKUTSCH N., OGILVIE A.L.J., RÖSSNER S., KOCH F., ROMANI N., SCHULER G. (1999):
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow.
J. Immunol. Meth. 223, 77-92 MA X. u. TRINCHIERI G. (2001):
Regulation of interleukin-12 production in antigen- presenting cells.
Adv. Immunol. 79, 55-92
MAEDA S., TSUCHIDA H., SHIBATA S., KAWAKAMI T., TSUKUI T., OHBA Y., FUKATA T., KITAGAWA H. (2008):
Expression analysis of CCL27 and CCL28 mRNA in lesional and non-lesional skin of dogs
with atopic dermatitis.
J. Vet. Med. Sci. 70, 51-55
MANNON P.J., FUSS I.J., MAYER L., ELSON C.O., SANDBORN W.J., PRESENT D., DOLIN B., GOODMAN N., GRODEN C., HORNUNG R.L., QUEZADO M., YANG Z., NEURATH M.F., SALFELD J., VELDMAN G.M., SCHWERTSCHLAG U., STROBER W.
(2004):
Anti-interleukin-12 antibody for active Crohn's disease.
N. Engl. J. Med. 351, 2069-2079
MATTNER F., MAGRAM J., FERRANTE J., LAUNOIS P., DI PADOVA K., BEHIN R., GATELY M.K., LOUIS J.A., ALBER G. (1996):
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.
Eur. J. Immunol. 26, 1553-1559
MC INTYRE K.W., SHUSTER D.J., GILLOOLY K.M., WARRIER R.R., CONNAUGHTON S.E., HALL L.B., ARP L.H., GATELY M.K., MAGRAM J. (1996):
Reduced incidence and severity of collagen-induced arthritis in interleukin-12-deficient mice.
Eur. J. Immunol. 26, 2933-2938
MORGAN R., MC ALLISTER B., CROSS L., GREEN D., KORNFELD H., CENTER D., CRUIKSHANK W. (2007):
Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.
J. Immunol. 178, 8081–8089
MORSE K.L.,BEHAN J., LAZ T.M., WEST R.E., GREENFEDER S.A., ANTHES J.C., UMLAND S., WAN Y., HIPKIN R.W., GONSIOREK W., SHIN N., GUSTAFSON E.L., QIAO X., WANG S., HEDRICK J.A., GREENE J., BAYNE M., MONSMA F.J. (2001):
Cloning and characterization of a novel human histamine receptor.
J. Pharmacol. Exp. Ther. 296, 1058-1066
MOSMANN T.R., COFFMAN R.L. (1989):
Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties.
Ann. Rev. Immunol. 7, 145-173
MURPHY C.A., LANGRISH C.L., CHEN Y., BLUMENSCHEIN W., MC CLANAHAN T., KASTELEIN R.A., SEDGWICK J.D., CUA D.J. (2003):
Divergent pro- and antiinflammatory roles for IL-23 and IL- 12 in joint autoimmune inflammation.
J. Exp. Med. 198, 1951-1957
MURRAY H.W., TSAI C.W., LIU J., MA X. (2006):
Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18.
Infect. Immun. 74, 4370- 4374
NAKAMURA T., ITADANI H., HIDAKA Y., OHTA M., TANAKA K. (2000):
Molecular cloning and characterization of a new human histamine receptor, H4R.
Biochem. Biophys. Res. Commun. 279, 615-620 NEUMANN D., BEERMANN S., SEIFERT R. (2010)
Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?
Pharmacology 85, 217-223
NGUYEN T., SHAPIRO D., GEORGE S., SETOLA V., LEE D., CHENG R., RAUSER L., LEE S., LYNCH K., ROTH B., O’DOWD B. (2001):
Discovery of a novel member of the histamine receptor family.
Mol. Pharmacol. 59, 427–433 NING-WEI Z. (2010):
Interleukin (IL)-35 is raising our expectations.
Rev. Med. Chil. 138, 758-766
NUTTALL T.J., KNIGHT P.A., MCALEESE S.M., LAMB J.R., HILL P.B. (2002a):
T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis.
Vet. Immunol. Immunopathol. 87, 379-384
NUTTALL T.J., KNIGHT P.A., MCALEESE S.M., LAMB J.R., HILL P.B. (2002b):
Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis.
Clin. Exp. Allergy 32, 789-795
O ́GARRA A. (1998):
Cytokines induce the development of functionally heterogenous T-helper cell subsets.
Immunity 8, 275-283
O ́GARRA A. u. ARAI N. (2000):
The molecular basis of T-helper 1 and T-helper 2 cell differentiation.
Trends Cell Biol. 10, 542-550
ODA T., MORIKAWA N., SAITO Y., MASUHO Y., MATSUMOTO S. (2000):
Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes.
J. Biol. Chem. 275, 36781–36786
ODA T., MATSUMOTO S., MASUHO Y., TAKASAKI J., MATSUMOTO M., KAMOHARA M., SAITO T., OHISHI T., SOGA T., HIYAMA H., MATSUSHIME H., FURUICHI K. (2002):
cDNA cloning and characterization of porcine histamine H4 receptor.
Biochim. Biophys. Acta 1575, 135-138
ODA T., MATSUMOTO S., MATSUMOTO M., TAKASAKI J., KAMOHARA M., SOGA T., HIYAMA H., KOBORI M., KATOH M. (2005):
Molecular cloning of monkey histamine H4 receptor.
J. Pharmacol. Sci. 98, 319-322
OH C., SUZUKI S., NAKASHIMA I., YAMASHITA K., NAKANO K. (1988):
Histamine synthesis by non-mast cells through mitogen-dependent induction of histidine decarboxylase.
Immunology 65, 143– 148
OHTANI T., AIBA S., MIZUASHI M., MOLLAH Z.U., NAKAGAWA S., TAGAMI H.
(2003):
H1 and H2 histamine receptors are absent on Langerhans cells and present on dermal dendritic cells.
J. Invest. Dermatol. 121, 1073-1079.
OHTSU H., TANAKA S., TERUI T., HORI Y., MAKABE-KOBAYASHI Y., PEJLER G., TCHOUGOUNOVA E., HELLMAN L., GERTSENSTEIN M., HIRASAWA N., SAKURAI E., BUZAS E., KOVACS P., CSABA G., KITTEL A., OKADA M., HARA M., MAR L., NUMAYAMA-TSURUTA K., ISHIGAKI-SUZUKI S., OHUCHI K., ICHIKAWA A., FALUS A., WATANABE T., NAGY A. (2001):
Mice lacking histidine decarboxylase exhibit abnormal mast cells.
FEBS Lett. 502, 53-56
OLIVRY T. u. HILL P.B. (2001):
The ACVD task force on canine atopic dermatitis (XVIII): histopathology of skin lesions.
Vet. Immunol. Immunopathol. 81, 305-309
OPPMANN B., LESLEY R., BLOM B., TIMANS J.C., XU Y., UNTE B., VEGA F., YU N., WANG J., SINGH K., ZONIN F., VAISBERG E., CHURAKOVA T., LIU M., GORMAN D., WAGNER J., ZURAWSKI S., LIU Y., ABRAMS J.S., MOORE K.W., RENNICK D., DE WAAL-MALEFTY R., HANNUM C., BAZAN J.F., KASTELEIN R.A. (2000):
OPPMANN B., LESLEY R., BLOM B., TIMANS J.C., XU Y., UNTE B., VEGA F., YU N., WANG J., SINGH K., ZONIN F., VAISBERG E., CHURAKOVA T., LIU M., GORMAN D., WAGNER J., ZURAWSKI S., LIU Y., ABRAMS J.S., MOORE K.W., RENNICK D., DE WAAL-MALEFTY R., HANNUM C., BAZAN J.F., KASTELEIN R.A. (2000):