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% Prozent

ABCB1 ATP-Binding Cassette, Subfamily B, Member 1

adap. Adaptive

AP1 Anionic Peroxidase 1

APS Ammoniumpersulfat

Areg Amphiregulin

ARPC2 Actin-Related Protein 2

ATF Activating Transcription Factor 2 ATG16L1 Autophagy Related 16-Like 1 β-Gal β-Galaktosidase

B6 C57/BL6J(B6)-Il10

-/-BACH2 BTB and CNC homology 1 Basic Leucine Zipper Transcription Factor 2

BCL6 B-Cell Leukemia/Lymphoma 6

Bp Basenpaar

BSA Bovines Serum Albumin

BSN Basonuclein

BTNL2 Butyrophilin-Like 2 bzw. beziehungsweise

C11orf30 Chromosome 11 Open Reading Frame 30 C3Bir C3H/HeJBir-Il10

-/-CARD Caspase Activated Recruitment Domain CCDC122 Coiled-Coil Domain Containing 122

CCL Chemokine (C-C motif) Ligand

CCNY Cycline Y

CCR 6 Chemokine(C-C motif) receptor 6 CD Cluster of differentiation

Cdcs Cytokine deficiency induced colitis susceptibility CDH1 Cadherin 1 Type 1

CDKAL 1 Cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1

cDNS zirkuläre Ribonukleinsäure

CED Chronisch Entzündliche Darmerkrankung CEP72 Centrosomal Protein 72kDa

cfu colony forming untis

CIITA Class II Major Histocompatibility Complex Transactivator CLN Ceroid-Lipofuscinosis Neuronal 3

cm Zentimeter

CMV Cytomegalievirus

CPEB Cytoplasmic Polyadenylation Element Binding Protein CREM cAMP-Response Element Modulator

CU Colitis Ulcerosa

CUL2 Cullin 2

DENND1B Differentially Expressed in Normal and Neoplastic Cells/ MAP-kinase Activating Death Domain Containing 1B

DLG 5 Disks Large Homolog 5 DMSO Dimethylsulfoxid

DNMT3A DNA Methyltransferase 3 Alpha DNS Desoxyribonukleinsäure

DSS Dextran Sodium Sulfat DTT Dithiothreitol

E2F E2F Transcription Factor ECM Extracellular Matrix Protein 1 E. coli Escherichia coli

EDTA Ethylendiamintetraacetat

EIF3C Eukaryotic Translation Initiation Factor 3 Subunit C ELISA Enzyme Linked Immunosorbant Assay

ENOX 1 Ecto-NOX Disulfide-Thiol Exchanger 1 ERAP Endoplasmic Reticulum Aminopeptidase ESRRA Estrogen-related Receptor Alpha

Fa. Firma

FADS Fatty Acid Desaturase

FAM92B Family with Sequence Similarity 92, member B FCGR2A Fc Fragment of IgG Low Affinity IIa Receptor FMO4 Flavin-containing Monooxygenase 4 FUT2 Fucosyltransferase 2

g Gramm

g g-Beschleunigung

G418 Geneticin

GALC Galactosylceramidase

GAPDH Glycerinaldehyd-3-Phosphat-Dehydrogenase Gbp Guanylate binding protein

GCKR Glucokinase Regulator GFP grün floureszierendes Protein

Gnb1 Guanine Nucleotide Binding Protein 1 GPI Glykosylphoshpatidolinositol

GPR65 G Protein-coupled Receptor 65 GPX1 Glutathione Peroxidase 1 GWAS Genomweite Assoziationsstudien HERC2 Hect Domain and Rolled Leaf 2 HLA Human Leukocyte Antigen HNF4A Hepatocyte Nuclear Factor 4 Alpha HORMAD2 HORMA domain containing 2

HPLC High-Performance Liquid Chromatography HRP Horseradichperoxidase

HSP Heat Shock Protein

IBD Inflammatory Bowel Disease ICAM Intercellular Adhesion Molecule

ICOSLG Inducible T-cell Costimulator Ligand Gen

Il Interleukin

Il10RA Interleukin 10 Receptor α Il1Rl1 Interleukin 1 Receptor-like 1 Il10RB Interleukin 10 Receptor β Il17REL Interleukin 17 Receptor E-like

Il18RAP Interleukin 18 Receptor Accessory Protein Il23R Interleukin 23 Receptor

INPP5E Inositol Polyphosphate-5-phosphatase INSL Insulin-Like

IRF Interferon Regulatory Factor

IRGM Immunity-Related GTPase Family M Protein JAK 2 Janus Kinase 2

KB Kilobase

kDa kilo Dalton

KIF21B Kinesin Family Member 21B KPNA7 Karyopherin Alpha 7

L Liter

LB Luria Bertani

LIF Leukemia Inhibitory Factor LPS Lipopolysaccharid

LRRK2 leucine-rich repeat kinase 2

Ly6g6c Lymphocyte Antigen 6 Complex, Locus G6C

mA Milliampere

MAP3K7IP1 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1

MC Morbus Crohn

mCD membrangebundenes Cluster of differentiation MDR1 Multi Drug Resistance 1

MEF Murine Embryonale Fibroblasten MEM Modified Eagle’s Medium MHC Major Histocompatibility Complex MST1 Macrophage-Stimulating 1 MTMR3 Myotubularin Related Protein 3

µg Mikrogramm

mg Milligramm

µL Mikroliter

mL Milliliter

mMol Millimol

MOPS 3-(N-Morpholino)-Propansulfonsäure mRNS messenger Ribonukleinsäure

MUC Mucin

MYO9B Myosin IXB

NDFIP1 Neural Precursor Cell Expressed developmentally Down-regulated 4 Family Interacting Protein 1

NKX2-3 Natural Killer Cell-associated Antigen 2 Transcription Factor Related, Locus 3

nm Nanometer

NUPR1 Nuclear Protein Transcriptional Regulator 1 NOD nucleotide-binding oligomerization domain

NR Nitrat Reductase

OCT Organic Cation Transporter

OD Optische Dichte

ORMDL3 Orosomucoid 1 Like 3

P53 Transformation Related Protein 53 PAX2 Paired Box Gene 2

PBS Phosphate Buffered Saline PCR Polymerase Chain Reaction Pla2g2a Phospholipase A2 group IIA PLCL1 Phospholipase C-like 1

PPARG Peroxisome Proliferator-Activated Receptor Gamma

PRDX Peroxiredoxin

PSMG1 Proteasome (Prosome, Macropain) Assembly Chaperone 1

PTGER4 Prostaglandin E Receptor Subtype EP4

PTPN1 Protein Tyrosine Phosphatase, Non-Receptor Type 1 PTPN 2 Protein Tyrosine Phosphatase, Non-Receptor Type 2

PTPN22 Protein Tyrosine Phosphatase Non-Receptor Type 22 (lymphoid)

pMol Picomol

PTPN22 Protein Thyrosin Phosphatase 22 PUS10 Pseudouridylate Synthase 10 qRT Quantitative Real-Time QTL Quantitative Trait Loci

® Registrierte Warenmarke

RASIP Ras Interacting Protein

REL Reticuloendotheliosis Viral Oncogene Homolog RNASE2 Ribonuclease A Family 2

RNS Ribonukleinsäure rpm revolutionso per minute rRNS ribosomale Ribonukleinsäure

RT Reverse Transkription

RTEL1 Regulator of Telomere Elongation Helicase 1

SATB2 Special AT-rich Sequence Binding Protein Homebox 2 SCAMP Secretory Carrier Membrane Protein

sCD soluble Cluster of Differentiantion

SDCCAG3 Serologically Defined Colon Cancer Antigen 3 SDS Sodium Dodecyl Sulfat

SEC16A Putative UDP-Acetylglucosamine-Peptide N-Acetylglucosaminyltransferase Homolog 16 A SLC Single Level Cell

SMAD3 Mothers Against Decapentaplegic Homolog 3 SMURF1 SMAD-specific E3 Ubiquitin-protein Ligase 1

SNAP4 Small Nuclear RNA Activating Complex Polypeptide 4 SNP single nukleotide polymorphism

SP1 Specificity Protein 1

SP140 SP140 Nuclear Body Protein SP2 Transkriptionsfaktor SP2 SPF Specified Pathogen Free

ssp. Subspezies

STAT Signal Transducer and Activator of Transcription

SULT1A1 Sulfotransferase Family Cytosolic 1A Phenol-Preferring Member

T/A Thymin/Adenin

TAGAP T-cell Activation RhoGTPase Activating Protein TFBS Transkriptionsfaktorbindunsstelle

Th T-Helfer

THADA Thyroid Adenoma Associated TL1A TNF-like ligand 1 A

TLR Toll Like Receptor TNF Tumor-Nekrose-Faktor

TNFRSF6B Tumor Necrosis Factor Receptor Superfamily 6B TNFSF15 Tumor Necrosis Factor Superfamily Member 15 TPPP Tubulin Polymerization Promoting Protein TR2 Nuclear Receptor Subfamily 2 Group C Member 1 TRAF Tumor-Nekrose-Faktor-Rezeptor-α assoziierter Faktor TRIF Toll-Like Receptor Adaptor Molecule 2

tRNS transfer Ribonukleinsäure

TYK Tyrosinkinase

u.a. unter anderem

UBE2D1 Ubiquitin-conjugating Enzyme E2D 1 USP12 Ubiquitin Specific Peptidase 12

UV Ultraviolett

V Volt

VAMP Vesicle-associated Membrane Protein

Vol. Volumen

z.B. zum Beispiel

ZFP36L1 Zinc Finger Protein 36 C3H Type-like 1 ZMIZ1 Zinc Finger MIZ-type Containing 1 ZNF 365 Zinc Finger 365

ZPBP Zona Pellucida Binding Protein