AARDEN, L.A., P. LANDSDORP u. E. DE GROOT (1985):
A growth factor B cell hybridomas produced by human monocytes.
Lymphokines 10, 175-185 ACKERMAN, G.A. (1971):
The human neutrophilic myelocyte. A correlated phase and electron microscopic study.
Z. Zellforsch. Mikrosk. Anat. 121, 153-170
AKIRA, S., T. TAGA u. T. KISHIMOTO (1993):
Interleukin-6 in biology and medicine.
Adv. Immunol. 54, 1-78
ALBERTS, K.A., I. NOREN, M. RUBIN u. S. TÖRNGREN (1986):
Respiratory distress following major trauma.
Acta Orthop. Scand. 57, 158-162
ALLAN, G., P. BHATTACHERJEE, C.D. BROOK, N.G. READ u. A.J. PARKE (1985):
Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte accumulation into an experimental myocardial infarct – the effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation.
J. Cardiovasc. Pharmacol. 7, 1154-1160
ANDERSON, B.O., R.S. POGGETTI, P.F. SHANLEY, D.D. BENSARD, J.M.
PITMAN, D.W. NELSON; G.J.R. WHITMAN, A. BANERJEE u. A.H. HARKEN (1991):
Primed neutrophils injure rat lung through a platetelet-activating factor-dependent mechanism.
J. Surg. Res. 50, 510-514
ANDERSON, D.C. u. T.A. SPRINGER (1987):
Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins.
Annu. Rev. Med. 38, 175-194
ARFORS, K.E., C. LUNDBERG, L. LINDBOM, K. LUNDBERG, P.G. BEATTY u.
J.M. HARLAN (1987):
A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo.
Blood 69, 338-340
ASHBAUGH, D.G., D.B. BIGELOW, T.L. PETTY u. B.E. LEVINE (1967):
Acute respiratory distress in adults.
Lancet 2, 319-323
Literaturverzeichnis 65 AUFMKOLK, M. u. E. LETSCH (1996):
Ergebnisse peripherer arterieller Gefäßverletzungen beim polytraumatisierten Patienten.
Unfallchirurg 60, 23-29
AUST, S.D. u. B.A. SVINGEN (1982):
The role of iron in enzymatic lipid peroxidation.
In: Free radicals in biology von W.A. PRYOR (Hrsg.) Academic, New York, S. 1-28
BABA, M., R. SNOECK, R. PAUWELS u. E. DECLERCQ (1988):
Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus.
Origin of granules in polymorphonuclear leukocytes. Two types derived from opposite faces of the Golgi complex in developing granulocytes.
J. Cell Biol. 28, 277-301
BAINTON, D.F., J.L. ULLYOT u. M.G.FARQUAR (1971):
The development of neutrophilic polymorphonuclear leukocytes in human bone marrow.
Origin and content azurophil and specific granules.
J. Exp. Med. 134, 907-934
BARGATZE, R.F., S. KURK, G. WATTS, T.K. KISHIMOTO, C.A. SPEER u. M.A.
JUTILA (1994):
In vivo and in vitro functional examination of a conserved epitope of L- and E-selectin crucial for leukocyte-endothelial cell interactions.
J. Immunol. 152, 5814-5825 BARIE, P.S. (1993):
Acute respiratory failure.
In: Surgical intensive care von P.S. BARIE und G.T. SHIRES (Hrsg.) Little, Brown and Company, Boston, S. 227
BARIE, P.S. u. R.J. MULLINS (1988):
Experimental methods in the pathogenesis of limb ischemia.
J. Surg. Res. 44, 284-307 BAUE, A.E. (1975):
Multiple, progressive, or sequential systems failure. A syndrom of the 1970‘s.
Surgery 110, 779-781
Literaturverzeichnis 66 BAUER, J., U. GANTER, T. GEIGER, U. JACOBSHAGEN, T. HIRANO, T.
MATSUDA, T. KISHIMOTO, T.ANDUS, G. ACS, W. GEROK u. G.CILIBERTO (1988):
Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages.
Blood 72, 1134-1140
BAUER, M. u. I. MARZI (1994):
Leukozyten-Endothel-Interaktion als Ausdruck einer hepatischen Entzündungsreaktion im experimentellen Schocksyndrom.
Anästhesiol. Intensivmed. Notfallmed. Schmerzther. 29, 46-50
BAUMHUETER, S., M.S. SINGER, W. HENZEL, S. HEMMERICH, M. RENZ, S.D.
ROSEN u. L.A. LASKY (1993):
Binding of L-selectin to the vascular sialomucin CD34.
Science 262, 436-438
BEATTY, P.G., OCHS, J.M. HARLAN, T.H. PRICE, H. ROSEN, R.F. TAYLOR, J.A. HANSEN u. S.J. KLEBANOFF (1984):
Absence of monoclonal-antibody-defined protein complex in boy with abnormal leucocyte function.
Lancet 1, 535-537
BELKIN, M., W.L. LAMORTE u. J.G. WRIGHT (1989):
The role of leukocytes in the pathophysiology of skeletal muscle ischemic injury.
J. Vasc. Surg. 10, 14-18
BENNETT, T.A., E.B. LYNAM, L.A. SKLAR u. S.ROGELJ (1996):
Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leucocytes; functional consequences for neutrophil aggregation.
J. Immunol. 156, 3093-3097 BERG, R.D. (1992):
Translocation of enteric bacteria in health and disease.
In: COTTIER, H. u. R. KRAFT (Hrsg.): Gut-derived infectious-toxic shock (GITS).
Curr. Stud. Hematol. Blood Transfus. Nr. 59, Karger Verlag, Basel, 44-65 BERNARD, G.R. (1990):
Potential of N-acetylcysteine as treatment for the adult respiratory distress syndrome.
Eur. Respir. J. 3, 496S-498S
BERNARD, G.R., A. ARTIGAS, K.L. BRIGHAM, J.CARLET, K. FALKE, L.
HUDSON, M. LAMY, J.R. LEGALL, A. MORRIS u. R. SPRAGG (1994):
The American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination.
Am. J. Respir. Crit. Care Med. 149, 818-824
Literaturverzeichnis 67 BIELSKI, B.H. u. G.G. SHIUE (1979):
Reaction rates of superoxide radicals with the essential amino acids.
In: Oxygen free radicals and tissue damage von Ciba Foundation New York (Hrsg.) Elsevier, Amsterdam, S. 43-56
Immunologic dissonance: a continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS).
Ann. Intern. Med. 125, 680-687 BONE, R.C. (1996b):
Sir Isaac Newton, sepsis, SIRS, and CARS.
Crit. Care Med. 24, 1125-1128 BONE, R.C. (1996c):
Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation.
Crit. Care Med. 24, 163-172 BONE, R.C. (1996d):
Why the sepsis trials failed.
JAMA 276, 565-566
BONE, R.C., R.A. BALK, F.B. CERRA, R.P. DELLINGER, A.M. FEIN, W.A.
KNAUS, R.M.H. SCHEIN u. W.J. SIBBALD (1992):
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.
Chest 101, 1644-1655
BRENNER, B., E. GULBINS, K. SCHLOTTMANN, U. KOPPENHOEFER, G.L.
BUSCH, B. WALZOG, M. STEINHAUSEN, K.M. COGGESHALL, O.
LINDERKAMP u. F. LANG (1996):
L-selectin activates the Ras pathway via the tyrosine kinase p56lck. Proc. Natl. Acad. Sci. USA 93, 15376-15381
Literaturverzeichnis 68 BRENNER, B., S. WEINMANN, H. GRASSME, F. LANG, O. LINDERKAMP u. E.
GULBINS (1997):
L-selectin activates JNK via src-like tyrosine kinases and the small G-protein Rac.
Immunology 92, 214-219 BUDELMANN, G. (1969):
Hugo Schottmüller, 1867-1936. The problem of sepsis.
Internist (Berl.) 10, 92-101 BURCHARDI, H. (1987):
Das akute Lungenversagen – eine kritische Analyse.
Langenbecks Arch. Chir. 372, 53-58
BURGER, R.M., A.R. BERKOWITZ, J. PREISACH u. S.B. HORWITZ (1980):
Origin of malodialdehyde from DNA degraded by Fe(II) belomycin.
J. Biol. Chem. 255, 11832-11838 BUTCHER, E.C. (1991):
Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity.
Cell 67, 1033-1036
CALANDRA, T., J. GERAIN, D. HEUMANN, J.D. BAUMGARTNER u. M.P.
GLAUSER (1991):
High circulating levels of interleukin-6 in patients with septic shock: evolution during sepsis, prognostic value, and interplay with other cytokines.
Am. J. Med. 91, 23-29
CARDEN, D.L., J.K. SMITH u. R.J. KORTHUIS (1990):
Neutrophil-mediated microvascular dysfunction in post-ischemic canine skeletal muscle.
Circ. Res. 66, 1436-1444
CARRICO, C.J., J.L.MEAKINS, J.C. MARSHALL, D. FRY u. R.V. MAIER (1986):
Multiple organ failure syndrome.
Arch. Surg. 121, 196-208
CERASOLI, F., P.J. MCKENNA, D.L. ROSOLIA, K.H. ALBERTINE, S.P. PETERS u. M.H. GEE (1990):
Superoxide anion release from blood and bone marrow neutrophils is altered by endotoxemia.
Circ. Res. 67, 154-165
CERRA, F., M. MADDAUS u. D. DUNN (1992):
Selective gut decontamination reduces nosocomial infections and length of stay but not mortality or organ failure in surgical intensive care unit patients.
Arch. Surg. 127, 163-169
Literaturverzeichnis 69 CHURCH, F.C., J.B. MEADE, R.E. TREANOR u. H.C. WHINNA (1989):
Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin.
J. Biol. Chem. 264, 3618-3623
CIPOLLE, M.D., M.D. PASQUALE u. F.B. CERRA (1993):
Secondary organ dysfunction. From clinical perspectives to molecular mediators.
Crit. Care Clin. 9, 261-298
COLLINS, T., A. WILLIAMS, G.I. JOHNSTON, J. KIM, R. EDDY, T. SHOWS, M.A. GIMBRONE u. M.P. BEVILACQUA (1991):
Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule-1.
Multiple organ failure: pathophysiology and potential future therapy.
Ann. Surg. 216, 117-134
DEITCH, E.A., W. BRIDGES, L. MA, R.D. BERG, R.D. SPECIAN u. N. GRANGER (1990a):
Hemorrhagic shock-induced bacterial translocation: The role of neutrophils and hydroxyl radicals.
J. Trauma 30(8), 942-952
DEITCH, E.A., J. MORRISON, R. BERG u. R.D. SPECIAN (1990b):
Effect of hemorrhagic shock on bacterial translocation, intestinal morphology, and intestinal permeability in conventional and antibiotic-decontaminated rats.
Crit. Care Med. 18(5), 528-536
DELLINGER, E.P., T.J. BABINEAU, P. BLEICHER, A.B. KAISER, G.B. SEIBERT, R.G. POSTIER, S.B. VOGEL, J. NORMAN, D. KAUFMAN, S. GALANDIUK u.
R.E. CONDON (1999):
Effect of PGG-glucan on the rate of serious postoperative infection or death observed after high-risk gastrointestinal operations. Betafectin Gastrointestinal Study Group.
Arch. Surg. 134, 977-983 DEMLING, R.H. (1985):
Mechanisms of pulmonary vascular injury in sepsis.
In: The pulmonary circulation and acute lung injury von S.I. SAID (Hrsg.) Futura Publishing Co., Inc., Mount Kisco, S. 403-427
Literaturverzeichnis 70 DE WAAL, M.R., R. ABRAMS, B. BENNET, C.G. FIGDOR u. J.E. DE VRIES (1991):
Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
J. Exp. Med. 174, 1209-1220 DINARELLO, C.A. (1996):
Cytokines as mediators in the pathogenesis of septic shock.
Curr. Top. Microbiol. Immunol. 216, 133-165
DINARELLO, C.A., J.A. GELFLAND u. S.M. WOLFF (1993):
Anticytokine strategies in the treatment of the systemic inflammatory response syndrome.
JAMA 269, 1829-1835
DUBAYO, B.A. u. R.W. CARLSON (1988):
Post-infectious ARDS: mechanisms of lung injury and repair.
Crit. Care Clin. 4, 229-243
DWENGER, A., G. REGEL u. G. SCHWEITZER (1993):
Cellular and humoral reactions of the nonspecific immun system of polytraumatized patients with and without the adult respiratory distress syndrom.
In: Immunconsequences of trauma, shock and sepsis von E. FAIST, J. NINNEMANN u. D.
GREE (Hrsg.)
Springer Verlag, Berlin, S. 241-246
EISEMAN, B., R. BEART u. L. NORTON (1977):
Multiple organ failure.
Surg. Gynaecol. Obstet. 144; 323-326
ENK, A.H., V.L. ANGELONI, N.C. UDEY u. S.J. KATZ (1993):
Inhibition of Langerhans cell antigen-presenting function by IL-10.
J. Immunol. 151, 2390-2398
FAZELI, A. u. L. RICHARDS (1984):
Chemiluminescence induced by phagocytosis of Escherichia Coli by polymorphonuclear leucocytes.
J. Gen. Microbiology 130, 2267-2275 FINK, M.P. (1991):
Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis.
Crit. Care Med. 19(5), 627-641
FIORENTINO, D.F., M.W. BOND u. T.R. MOSMANN (1989):
Two types of mouse T-helper cell: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.
J. Exp. Med. 170, 2081-2095
Literaturverzeichnis 71 FIORENTINO, D.F., A. ZLOTNICK, T.R. MOSMANN, M. HOWARD u. A.
O’GARRA (1991):
IL-10 inhibits cytokine production by activated macrophages.
J. Immunol. 147, 3815-3822 FLAHERTY, J.T. (1991):
Myocardial injury mediated by oxygen free radicals.
Am. J. Med. 91, 79S-85S
FUJISHIMA, S. u. N. AIKAWA (1995):
Neutrophil-mediated tissue injury and ist modulation.
Intensive. Care Med. 21, 277-285
FUKUSHIMA, R., J.W. ALEXANDER, L. GIANOTTI u. C.K. OGLE (1994):
Isolated pulmonary infection acts as asource of systemic tumor necrosis factor.
Crit. Care Med. 22, 114-120
FURIE, M.B. u. D.D. MCHUGH (1989):
Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-alpha.
J. Immunol. 143, 3309-3317
FURIE, M.B., B.L. NAPRSTEK u. S.C. SILVERSTEIN (1987):
Migration of neutrophils across monolayers of cultured microvascular endothelial cells.
An in vitro model of leucocyte extravasation.
J. Cell Sci. 88, 161-175
GALLATIN, W.M., I.L. WEISSMAN u. E.C. BUTCHER (1983):
A cell-surface molecule involved in organ-specific homing of lymphocytes.
Nature 304, 30-34
GAMBLE, J.R., J.M. HARLAN, S.J. KLEBANOFF u. M.A. VADAS (1985):
Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.
Proc. Natl. Acad. Sci. USA 82, 8667-8671
GANDO, S., T. KAMEKE, S. NANZAKI u. Y. NAKANISHI (1996):
Disseminated intravascular coagulation is a frquent comlication of systemic inflammatory response syndrome.
Thromb. Haemost. 75, 224-228
GASIC, A.C., G. MCGUIRE, S. KRATER, A.I. FARHOOD, M.A. GOLDSTEIN, C.W. SMITH, M.L. ENTMAN u. A.A. TAYLOR (1991):
Hydrogen peroxide pretreatment of perfused canine vessels induces ICAM-1 and CD18-dependent neutrophil adherence.
Circulation 84, 2154-2166
Literaturverzeichnis 72 GASTINNE, H., M. WOLFE u. F. DELATOUR (1992):
A controlled trial in intensive care units of selective decontamination of the digestive tract with nonabsorbable antibiotics.
N. Engl. J. Med. 326, 594-596
GOLDMAN, G., R. WELBOURN, J.M. KLAUSNER, L. KOBZIK, C.R. VALERI, D.
SHEPRO u. H.B. HECHTMAN (1992):
Mast cells and leukotrienesmediate neutrophil sequestration and lung edema after remote ischemia in rodents.
Surgery 112, 578-586
GOLDMAN, G., R. WELBOURN, I.S. PATERSON, J.M. KLAUSNER, L. KOBZIK, C.R. VALERI, D. SHEPRO u. H.B. HECHTMAN (1990):
Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent.
Surgery 107, 428-433
GOMEZ-JIMENEZ, J., A. SALGADO, M. MOURELLE, M.C. MARTIN, R.M.
SEGURA u. R. PERACAULA (1995):
L-arginine: nitric oxide pathway in endotoxemia and human septic shock.
Crit. Care Med. 23, 253-258
GORIS, R.J.A. u. J. DRAAISMA (1982):
Causes of death after blunt trauma.
J. Trauma 22, 141-146
GRAUFFEL, V., B. KLOAREG, S. MABEAU, P. DURAND u. J. JOZEFONVICZ (1989):
New natural polysaccharides with potent antithrombic activity fucans from brown algae.
Biomaterials 10, 363-367
GRECH, E.D., C.M. BELLAMY, M.J. JACKSON, R.A. MUIRHEAD, E.B.
FARAGHER u. D.R. RAMSDALE (1994):
Free-radical activity after primary coronary angioplasty in acute myocardial infarction.
Am. Heart J. 127, 1443-1449
GRIFFIN, J.D., O. SPERTINI, T.J. ERNST, M.P. BELVIN, H.B. LEVINE, Y.
KANAKURA u. T.F. TEDDER (1990):
GM-CSF and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.
J. Immunol. 145, 576-582
GRISWOLD, J. u. R.V. MAIER (1988):
Neutrophil phagocytosis during endotoxin-induced lung-injury.
J. Surg. Res. 44, 417-424
Literaturverzeichnis 73 HACK, C.E., E.R. DE GROOT, R.J.F. FELT-BERSMA, J.H.NUIJENS, R.J.M.
STRACK VAN SCHIJNDEL, A.J.M. EERENBERG-BELMER, L.G. THIJS u. L.A.
AARDEN (1989):
Increased plasma levels of interleukin-6 in sepsis.
Blood 74, 1704-1710 HARLAN, J.M. (1987):
Neutrophil-mediated vascular injury.
Acta Med. Scand. Suppl. 715, 123-129
HELFET, D.L., T. HOWEY, R. SANDERS u. K. JOHANSEN (1990):
Limb salvage versus amputation. Preliminary results of the Mangled Extremity Severtiy Score.
Clin. Orthop. 80-86
HELFGOTT, D.C., S.B. TATTER, U. SANTHANAM, R.H. CLARICK, N.
BHARDWAJ u. L.T. MAY (1989):
Multiple forms of IFN-β/IL-6 in serum and body fluids during acute bacterial infection.
J. Immunol. 142, 948-953
HERNANDEZ, L.A., M.B. GRISHAM, B. TWOHIG, K.E. ARFORS, J.M. HARLAN u. D.N. GRANGER (1987):
Role of neutrophils in ischemia-reperfusion-induced microvascular injury.
Am. J. Physiol. 253, H699-H703 HIRANO, T. (1994):
Interleukin 6.
In: The Cytokine Handbook 2nd ed.
Academic Press, New York, S. 145
HIRANO, T., K. YASUKAWA, H. HARADA, T. TAGA, Y. WATANABE, T.
MATSUDA, S. KASHIWAMURA, K. NAKAJIMA, K. KOYAMA u. A. IWAMATSU (1986):
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobin.
Nature 324, 73-76
HIRASAWA, H., T. SUGAI, Y. OHTAKE, S. ODA, K. MATSUDA u. N.
KITAMURA (1996):
Blood purification for prevention and treatment of multiple organ failure.
World J. Surg. 20, 482-486
HOOVER, R.L., J.M. ROBINSON u. M.J. KARNOVSKY (1987):
Adhesion of polymorphnuclear leucocytes to endothelium enhances the efficiency of detoxification of oxygen-free radicals.
Am. J. Pathol. 126, 258-268
Literaturverzeichnis 74 IBBOTSON, G.C. u. J.L. WALLACE (1989):
Beneficial effects of prostaglandin E2 in endotoxin shock are unrelated to effects on PAF-acether synthesis.
Prostaglandins 37, 237-250
INAUEN, W., D.K. PAYNE, P.R. KVIETYS u. D.N. GRANGER (1990):
Hypoxia/reoxygenation increases the permeability of endothelial cell monolayers: role of oxygen radicals.
Free Radic. Biol. Med. 9, 219-223
JENKINS, M.T., R.F. JONES, B. WILSON u. C.A. MOYER (1950):
Congestive atelectasis a complication of the intravenous infusion of fluids.
Ann. Surg. 132, 327-347
JESMOK, G.J. u. R.A. GUNTHER (1989):
In vivo biology of recombinant interleukin 2 infusion in sheep: cardiopulmonary manifestations of an intravascular immune inflammatory response.
Inflammation 13, 267-284
JOHNSTON, G.I., G.A. BLISS, P.J. NEWMAN u. R.P. MCEVER (1990):
Genomic structure of GMP-140, a member of the selectin family of adhesion receptors for leukocytes.
J. Biol. Chem. 265, 21381-21385
JONAS, E., A. DWENGER, B. LUEKEN u. U. BÖHME (1991):
Simultaneous measurement of endothelial cell damage, elastase release, and chemiluminescence response during interaction between polymorphnuclear leucocytes and endothelial cells.
In: Adult respiratory distress syndrome: an aspect of multiple organ failure; result of a prospective clinical study von J.A. STURM (Hrsg.)
Springer Verlag, Berlin, S. 281-293 JUNG, T.M. u. M.O. DAILEY (1990):
Rapid modulation of homing receptors (gp90Mel-14) induced by activators of protein kinase C. Receptor shedding due to accelerated proteolytic cleavage at the cell surface.
J. Immunol. 144, 3130-3136
JUTILA, M.A., L. ROTT, E.L. BERG u. E.C. BUTCHER (1989):
Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1.
J. Immunol. 143, 3318-3324
JUTILA, M.A., T.K. KISHIMOTO u. E.C. BUTCHER (1990):
Regulation and lectin activity of the human neutrophil lymph node homing receptor.
Blood 76, 178-183
Literaturverzeichnis 75 KANSAS, G.S., K.B. SAUNDERS, K. LEY, A. ZAKREWICZ, R.M. GIBSON, B.C.
FURIE, B. FURIE u. T.F. TEDDER (1994):
A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion.
J. Cell Biol. 124, 609-618
KAZUI, M., K.A. ANDREONI, G.M. WILLIAMS, B.A. PERLER, G.B. BULKLEY, C. BEATTIE, R.T. DONHAM, S.S. SEHNERT, J.F. BURDICK u. T.H. RISBY (1994):
Visceral lipid peroxidation occurs at reperfusion after supraceliac aortic cross-clamping.
J. Vasc. Surg. 19, 473-477
KINDT, G.C., J.E. GADEK u. J.E. WEILAND (1991):
Initial recruitment of neutrophils to alveolar structures in acute lung injury.
J. Appl. Physiol. 70, 1575-1585 KISHIMOTO, T. (1989):
The biology of interleukin-6.
Blood 74, 1-10
KISHIMOTO, T., M. HIBI, M. MURAKAMI, M. NARAZAKI, M. SAITO u. T.
TAGA (1992):
The molecular biology of interleukin 6 and its receptor.
Ciba Found. Symp. 167, 5-16
KISHIMOTO, T.K., M.A. JUTILA u. E.C. BUTCHER (1990):
Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.
Proc. Natl. Acad. Sci. USA 87, 2244-2248
KLAUSNER, J.M., H. ANNER, I.S. PATERSON, L. KOBZIK, C.R. VALERI, D.
SHEPRO u. H.B. HECHTMAN (1988):
Lower torso ischemia-induced lung injury is leukocyte dependent.
Ann. Surg. 208, 761-767
KLAUSNER, J.M., I.S. PATERSON, G. GOLDMAN, L. KOBZIK, C.R. VALERI, D.
SHEPRO u. H.B. HECHTMAN (1989):
Thromboxane A2 mediates increased pulmonary microvascular permeability following limb ischemia.
Circ. Res. 64, 1178-1189
KNAUS, W.A., E.A. DRAPER, D.P. WAGNER u. J.E. ZIMMERMANN (1985):
APACHE II: a severity of disease classification system.
Crit. Care Med. 13, 818-828
Literaturverzeichnis 76 KNAUS, W.A., D.P. WAGNER, E.A. DRAPER, J.E. ZIMMERMANN, M.
BERGNER, P.G. BASTOS, C.A. SIRIO, D.J. MURPHY, T. LOTRING, A.
DAMIANO u. F.E. HARRELL (1981):
The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults.
Chest 100, 1619-1636
KODAMA, M., T. TANI u. K. MAEKAWA (1995):
Endotoxin eliminating therapy in patients with severe sepsis – direct hemoperfusion using polymyxin B immobilized fiber column.
J. Jpn. Surg. 96, 277-285
KORTHUIS, R.J., M.B. GRISHAM u. D.N. GRANGER (1988):
Leucocyte depletion attenuates vascular injury in postischemic skeletal muscle.
Am. J. Physiol. 254, H823-H827
KORTHUIS, R.J., J.K. SMITH u. D.L. CARDEN (1989):
Hypoxic reperfusion attenuates postischemic microvascular injury.
Am. J. Physiol. 256, H315-H319
KREMER, J.P., D. JARRAR, U. STECKHOLZER u. W. ERTEL (1996):
Interleukin-1, -6 and tumor necrosis factor-alpha release is down-regulated in whole blood from septic patients.
Acta Haematol. 95, 268-273
KREUZFELDER, K., T. JOKA u. H.-O. KEINECKE (1988):
Adult respiratory distress syndrome as a specific manifestation of a general permeability defect in trauma patients.
Am. Rev. Respir. Dis. 137, 95-99
KUIJPERS, T.W., M. HOOGERWERF u. D. ROOS (1992):
Neutrophil migration across monolayers of resting or cytokine-activated endothelial cells.
Role of intracellular calcium changes and fusion of specific granules with the plasma membrane.
J. Immunol. 148, 72-77
KUROSE, I., D.C. ANDERSON, M. MIYASAKA, T. TAMATANI, J.C. PAULSON, R.F. TODD, J.R. RUSHE u. D.N. GRANGER (1994):
Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage.
Circ. Res. 74, 336-343
LASKY, L.A., M.S. SINGER, D. DOWBENKO, Y. IMAI, W.J. HENZEL, C.
GRIMLEY, C. FENNIE, N. GILLETT, S.R. WATSON u. S.D. ROSEN (1992):
An endothelial ligand for L-selectin is a novel mucin-like molecule.
Cell 69, 927-938
Literaturverzeichnis 77 LEMESHOW, S., D. TERES, J. KLAR, J.S. AVRUNIN, S.H. GEHLBACH u. J.
RAPOPERT (1993):
Mortality probability models (MPMII) based on an international cohort of intensive care unit patients.
JAMA 270, 2478-2486
LEWIS, R.A., K.F. AUSTEN u. R.J. SOBERMANN (1990):
Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in himan diseases.
N. Engl. J. Med. 323, 645-655
LEY, K., P. GAEHTGENS, C. FENNIE, M.S. SINGER, L.A. LASKY u. S.D. ROSEN (1991):
Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo.
Blood 77, 2553-2555
LUCAS, C.E., A.M. LEDGERWOOD, W.J. RACHWAL, D. GRABOW u. J.M.
SAXE (1991):
Colloid oncotic pressure and body water dynamics in septic and injured patients.
J. Trauma 31, 927-933
MA, X.L., A.S. WEYRICH, D.J. LEFER, M. BUERKE, K.H. ALBERTINE, T.K.
KISHIMOTO u. A.M. LEFER (1993):
Monoclonal antiboby to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium.
Circulation 88(2), 649-658
MAEKAWA, K., S. FUTAMI, M. NISHIDA, T. TERADA, H. INAGAWA, S.
SUZUKI u. K. ONO (1998):
Effects of trauma and sepsis on soluble L-selectin and cell surface expression of L-selectin and CD11b.
J. Trauma 44, 460-467 MALIK, A.B. (1985):
Mediators of pulmonary vascular injury and edema after thrombin.
In: The pulmonary circulation and acute lung injury von S.I. SAID (Hrsg.) Futura Publishing Co., Inc., Mount Kisco, S. 429-454
MANSHIP, L., R.D. MCMILLIN u. J.J. BROWN (1984):
The influence of sepsis and multisystem organ failure on mortality in the surgical intensive care unit.
Am. Surg. 50, 94-101
MANTHOUS, C.A., J.B. HALL u. R.W. SAMSEL (1993):
Endotoxin in human disease: Biologic effects and clinical evaluations of anti-endotoxin therapies.
Chest 104, 1872-1881
Literaturverzeichnis 78 MARCUS, B.C., C.W. WYBLE, K.L. HYNES u. B.L. GEWERTZ (1996):
Cytokine-induced increases in endothelial permeability occur after adhesion molecule expression.
Surgery 120, 411-416
MARSHALL, J.C., D.J. COOK, N.V. CHRISTOU, G.R. BERNARD, C.L. SPRUNG u. W.J. SIBBALD (1995):
Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome.
Crit. Care Med. 23, 1638-1652
MARUO, N., I. MORITA, M. SHIRAO u. S.I. MUROTA (1992):
IL-6 increases endothelial permeability in vitro.
Endocrinology 131, 710-714 MEAKINS, J.L. (1990):
Etiology of multiple organ failure.
J. Trauma 30, 165-168
MILLS, C.D., M.D. CALDWELL u. D.S. GANN (1989):
Evidence of a plasma-mediated „window“ of immundeficiency in rats following trauma.
J. Clin. Immunol. 9, 139-150
MIYAUCHI, T., Y. TOMOBE, R. SHIBA, T. ISHIKAWA, M. YANAGISAWA u. S.
KIMURA (1990):
Involvement of endothelin in the regulation of human vascular tonus. Potent vasoconstrictor effect and existence in endothelial cells.
Circulation 81, 1874-1880 MOON, V.H. (1932):
Pathology of shock.
Arch. Pathol. 14, 360-366
MOORE, K.W., A. O’GARRA, R. DE WAAL MALEFYT, P. VIEIRA u. T.R.
MOSMANN (1993):
NATHAN, C., S. SRIMAL, C. FARBER, E. SANCHEZ, L. KABBASCH, A. ASCH, J. GAILIT u. S.D. WRIGHT (1989):
Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.
J. Cell Biol. 109, 1341-1349
Literaturverzeichnis 79 NAVARRO, S., N. DEBILI, J.F. BERNAUDIN, W. VAINSCHENKER u. J. DOLY (1989):
Regulation of the expression of IL-6 in human monocytes.
J. Immunol. 142, 4339-4345 NEUHOF, H. (1991):
Actions and interactions of mediator systems and mediators in the pathogenesis of ARDS and multi organ failure.
Acta Anaesthesiol. Scand. 35, 7-14
NICHOLSON, M.W., A.N. BARCLAY, M.S. SINGER, S.D. ROSEN u. P.A. VAN DER MERWE (1998):
Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesion molecule-1.
J. Biol. Chem. 273, 763-770
NISHINO, T., G. YOKOYAMA, K. DOBASHI, M. FUJIHARA u. T. NAGUMO (1989):
Isolation, purification, and characterization of fucose-containing sulfated polysaccharides from the brown seaweed Ecklonia kurome and their blood-anticoagulant activities.
Carbohydr. Res. 186, 119-129 NOGARE, A.R.D. (1989):
Southwestern internal medicine conference: adult respiratory distress syndrome.
Am. J. Med. Sci. 298, 413-430
NUYTINCK, J.K.S., X.J. OFFERMANS, K. KUBAT u. R.J.A. GORIS (1988):
Whole body inflammation in trauma patients. An autopsy study.
Arch. Surg. 123, 1519-1524
ORD, D.C., T.J. ERNST, L.J. ZHOU, A. RAMBALDI, O. SPERTINI, J.D. GRIFFIN u. T.F. TEDDER (1990):
Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils.
J. Biol. Chem. 265, 7760-7767
PALMA-VARGAS, J.M., L. TOLEDO-PEREYRA, R.E. DEAN, J.M. HARKEMA, R.A.F. DIXON u. T.P. KOGAN (1997):
Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion.
J. Am. Coll. Surg. 185, 365-372
PALMBLAD, J., C.L. MALMSTEN, A.M. UDEN, O. RADMARK, L. ENGSTEDT u.
B. SAMUELSSON (1981):
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence.
Blood 58, 658-661
Literaturverzeichnis 80 PAPE, H.-C., G. REGEL, W. KLEEMANN u. K. KLAUSMEYER (1994):
Posttraumatic multiple organ failure – a report on clinical and autopsy findings.
Shock 2, 228-234
PAPE, H.-C., M. STALP, M. VAN GRIENSVEN, A. WEINBERG, M. DAHLWEIT u. H. TSCHERNE (1999):
Optimal timing for secondary surgery in polytrauma patients: an evaluation of 4,314 serious-injury cases.
Chirurg 70, 1287-1293
PARKS, D.A. u. D.N. GRANGER (1986):
Contributions of ischemia and reperfusion to mucosal lesion formation.
Am. J. Physiol. 250, G749-G753
PATANKAR, M.S., S. OEHNINGER, T. BARNETT, R.L. WILLIAMS u. G.F.
CLARK (1993):
A revised structure for fucoidan may explain some of its biological activities.
J. Biol. Chem. 268, 21770-21778
PATERSON, I.S., J.M. KLAUSNER, R. PUGATCH, P. ALLEN, J.A. MANNICK, D.
SHEPRO u. H.B. HECHTMAN (1989):
Noncardiogenic pulmonary edema after abdominal aortic aneurysm surgery.
Ann. Surg. 209, 231-236
PERCIVAL, E.G.V. u. A.G. ROSS (1950):
Part I. The isolation and purification of fucoidin from brown seaweeds.
J. Chem. Soc. 145, 717-720 PETERSON, B.T. (1992):
Permeability: theory vs. practice in lung research.
Am. J. Physiol. 262, L243-L256
PETRAK, R.A., R.A. BALK u. R.C. BONE (1989):
Prostaglandins, cyclo-oxygenase inhibitors, and thromboxane synthesis inhibitors in the pathogenesis of multiple systems organ failure.
Crit. Care Clin. 5, 303-314
PHILLIPS, M.L., E. NUDELMAN, F.C. GAETA, M. PEREZ, A.K. SINGHAL, S.
HAKOMORI u. J.C. PAULSON (1990):
ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex.
Science 250, 1130-1132
PICKER, L.J., R.A. WARNOCK, A.R. BURNS, C.M. DOERSCHUK, E.L. BERG u.
E.C. BUTCHER (1991):
The neutrophil selectin LECAM-1 presents carbohydrate ligand to the vascular selectins ELAM-1 and GMP-40.
Cell 66, 921-933
Literaturverzeichnis 81 PLATZER, C., C. MEISEL, K. VOGT, M. PLATZER u. H.D. VOLK (1995):
Up-regulation of monocytic IL-10 by tumor necrosis factor-α and cAMP elevating drugs.
Int. Immunol. 7, 517-523
POHLMAN, T.H., K.A. STANNESS, P.G. BEATTY, H.D. OCHS u. J.M. HARLAN (1986):
An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-α increases neutrophil adherence by a CDw18-dependent mechanism.
J. Immunol. 136, 4548-4553
PONTOPPIDAN, H., P.C. HÜTTEMEIER u. D.A. QUINN (1985):
Etiology, demography, and outcome.
In: Acute respiratory failure von W.M. ZAPOL und K.J. FALKE (Hrsg.) Marcel Dekker, New York
PREECE, G., G. MURPHY u. A. AGER (1996):
Metalloproteinase-mediated regulation of L-selectin levels on leucocytes.
J. Biol. Chem. 271, 11634-11640
PRESTERL, E., T. STAUDINGER, M. PETTERMENN, A. LASSNIGG, H.
BURGMANN, S. WINKLER, M. FRASS u. W. GRANINGER (1997):
Cytokine profile and correlation to the APACHE III and MPM II scores in patients with sepsis.
Am. J. Respir. Crit. Care Med. 156, 825-832
Am. J. Respir. Crit. Care Med. 156, 825-832