Abdurashidova, G., M. Deganuto, R. Klima, S. Riva, G. Biamonti, M. Giacca, and A.
Falaschi. 2000. Start sites of bidirectional DNA synthesis at the human lamin B2 origin. Science. 287:2023-6.
Abdurashidova, G., S. Riva, G. Biamonti, M. Giacca, and A. Falaschi. 1998. Cell cycle modulation of protein-DNA interactions at a human replication origin.
Embo J. 17:2961-9.
Adachi, Y., J. Usukura, and M. Yanagida. 1997. A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.
Genes Cells. 2:467-79.
Alexiadis, V., P.D. Varga-Weisz, E. Bonte, P.B. Becker, and C. Gruss. 1998. In vitro chromatin remodelling by chromatin accessibility complex (CHRAC) at the SV40 origin of DNA replication. Embo J. 17:3428-38.
Altschul, S.F., W. Gish, W. Miller, E.W. Myers, and D.J. Lipman. 1990. Basic local alignment search tool. J Mol Biol. 215:403-10.
Amon, A., S. Irniger, and K. Nasmyth. 1994. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell. 77:1037-50.
Anachkova, B., and J.L. Hamlin. 1989. Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element. Mol Cell Biol. 9:532-40.
Anderson, C.W., and T.H. Carter. 1996. The DNA-activated protein kinase: DNA-PK.
Curr Top Microbiol Immunol. 217:91-111.
Anderson, C.W., and S.P. Lees-Miller. 1992. The nuclear serine/threonine protein kinase DNA-PK. Crit Rev Eukaryot Gene Expr. 2:283-314.
Antequera, F., and A. Bird. 1993. Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci U S A. 90:11995-9.
Antequera, F., and A. Bird. 1999. CpG islands as genomic footprints of promoters that are associated with replication origins. Curr Biol. 9:R661-7.
Aparicio, O.M., D.M. Weinstein, and S.P. Bell. 1997. Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell. 91:59-69.
Apt, D., R.M. Watts, G. Suske, and H.U. Bernard. 1996. High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology. 224:281-91.
Araki, R., A. Fujimori, K. Hamatani, K. Mita, T. Saito, M. Mori, R. Fukumura, M.
Morimyo, M. Muto, M. Itoh, K. Tatsumi, and M. Abe. 1997. Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice. Proc Natl Acad Sci U S A. 94:2438-43.
Araujo, F.D., J.D. Knox, S. Ramchandani, R. Pelletier, P. Bigey, G. Price, M. Szyf, and M. Zannis-Hadjopoulos. 1999. Identification of initiation sites for DNA replication in the human dnmt1 (DNA-methyltransferase) locus. J Biol Chem.
274:9335-41.
Araujo, F.D., J.D. Knox, M. Szyf, G.B. Price, and M. Zannis-Hadjopoulos. 1998.
Concurrent replication and methylation at mammalian origins of replication.
Mol Cell Biol. 18:3475-82.
Austin, R.J., T.L. Orr-Weaver, and S.P. Bell. 1999. Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element. Genes Dev.
13:2639-49.
Baiker, A., C. Maercker, C. Piechaczek, S.B. Schmidt, J. Bode, C. Benham, and H.J.
Lipps. 2000. Mitotic stability of an episomal vector containing a human scaffold/matrix-attached region is provided by association with nuclear matrix. Nat Cell Biol. 2:182-4.
Baur, C.P., and R. Knippers. 1988. Protein-induced bending of the simian virus 40 origin of replication. J Mol Biol. 203:1009-19.
Becker, P.B., F. Weih, and G. Schutz. 1993. Footprinting of DNA-binding proteins in intact cells. Methods Enzymol. 218:568-87.
Beijersbergen, R.L., R.M. Kerkhoven, L. Zhu, L. Carlee, P.M. Voorhoeve, and R.
Bernards. 1994. E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev. 8:2680-90.
Bell, S.P., R. Kobayashi, and B. Stillman. 1993. Yeast origin recognition complex functions in transcription silencing and DNA replication. Science. 262:1844-9.
Bell, S.P., J. Mitchell, J. Leber, R. Kobayashi, and B. Stillman. 1995. The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing. Cell. 83:563-8.
Bell, S.P., and B. Stillman. 1992. ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature. 357:128-34.
Berezney, R., D.D. Dubey, and J.A. Huberman. 2000. Heterogeneity of eukaryotic replicons, replicon clusters, and replication foci. Chromosoma. 108:471-84.
Bielinsky, A.K., and S.A. Gerbi. 1998. Discrete start sites for DNA synthesis in the yeast ARS1 origin. Science. 279:95-8.
Biermann, E. 1999. I Bindungsstudien von hMcm5 an Kernprotein. II Bindungsstudien von hCdc6 an DNA. Diplomarbeit, Universität Konstanz.
Bird, A., M. Taggart, M. Frommer, O.J. Miller, and D. Macleod. 1985. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell. 40:91-9.
Bird, A., P. Tate, X. Nan, J. Campoy, R. Meehan, S. Cross, S. Tweedie, J. Charlton, and D. Macleod. 1995. Studies of DNA methylation in animals. J Cell Sci Suppl. 19:37-9.
Birnbaum, M.J., A.J. van Wijnen, P.R. Odgren, T.J. Last, G. Suske, G.S. Stein, and J.L. Stein. 1995. Sp1 trans-activation of cell cycle regulated promoters i s selectively repressed by Sp3. Biochemistry. 34:16503-8.
Birnboim, H.C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-23.
Black, A.R., and J. Azizkhan-Clifford. 1999. Regulation of E2F: a family of transcription factors involved in proliferation control. Gene. 237:281-302.
Blow, J.J., and R.A. Laskey. 1988. A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature. 332:546-8.
Blow, J.J., and S. Tada. 2000. Cell cycle. A new check on issuing the licence.
Nature. 404:560-1.
Blunt, T., N.J. Finnie, G.E. Taccioli, G.C. Smith, J. Demengeot, T.M. Gottlieb, R.
Mizuta, A.J. Varghese, F.W. Alt, P.A. Jeggo, and et al. 1995. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell. 80:813-23.
Bosco, G., W. Du, and T.L. Orr-Weaver. 2001. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat Cell Biol.
3:289-95.
Bosma, M.J., and A.M. Carroll. 1991. The SCID mouse mutant: definition, characterization, and potential uses. Annu Rev Immunol. 9:323-50.
Boubnov, N.V., K.T. Hall, Z. Wills, S.E. Lee, D.M. He, D.M. Benjamin, C.R. Pulaski, H.
Band, W. Reeves, E.A. Hendrickson, and et al. 1995. Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.
Proc Natl Acad Sci U S A. 92:890-4.
Bouchard, C., K. Thieke, A. Maier, R. Saffrich, J. Hanley-Hyde, W. Ansorge, S. Reed, P. Sicinski, J. Bartek, and M. Eilers. 1999. Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. Embo J.
18:5321-33.
Boulikas, T. 1996. Common structural features of replication origins in all life forms. J Cell Biochem. 60:297-316.
Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248-54.
Brandeis, M., D. Frank, I. Keshet, Z. Siegfried, M. Mendelsohn, A. Nemes, V.
Temper, A. Razin, and H. Cedar. 1994. Sp1 elements protect a CpG island from de novo methylation. Nature. 371:435-8.
Brown, G.W., and T.J. Kelly. 1998. Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast. J Biol Chem. 273:22083-90.
Brush, G.S., C.W. Anderson, and T.J. Kelly. 1994. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc Natl Acad Sci U S A. 91:12520-4.
Burhans, W.C., J.E. Selegue, and N.H. Heintz. 1986. Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain. Proc Natl Acad Sci U S A. 83:7790-4.
Burhans, W.C., L.T. Vassilev, M.S. Caddle, N.H. Heintz, and M.L. DePamphilis.
1990. Identification of an origin of bidirectional DNA replication in mammalian chromosomes. Cell. 62:955-65.
Burke, T.W., J.G. Cook, M. Asano, and J.R. Nevins. 2001. Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. J Biol Chem.
276:15397-408.
Burkhart, R. 1995. Untersuchungen über das menschliche Kernprotein P1Mcm3.
Dissertation, Universität Konstanz.
Burkhart, R., D. Schulte, D. Hu, C. Musahl, F. Gohring, and R. Knippers. 1995.
Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. Eur J Biochem. 228:431-8.
Burma, S., A. Kurimasa, G. Xie, Y. Taya, R. Araki, M. Abe, H.A. Crissman, H. Ouyang, G.C. Li, and D.J. Chen. 1999. DNA-dependent protein kinase-independent activation of p53 in response to DNA damage. J Biol Chem. 274:17139-43.
Byrne, C., M. Tainsky, and E. Fuchs. 1994. Programming gene expression in developing epidermis. Development. 120:2369-83.
Campanero, M.R., and E.K. Flemington. 1997. Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein. Proc Natl Acad Sci U S A. 94:2221-6.
Carpenter, C.L., and L.C. Cantley. 1996. Phosphoinositide kinases. Curr Opin Cell Biol. 8:153-8.
Chan, D.W., and S.P. Lees-Miller. 1996. The DNA-dependent protein kinase i s inactivated by autophosphorylation of the catalytic subunit. J Biol Chem.
271:8936-41.
Chan, G.K., S.A. Jablonski, V. Sudakin, J.C. Hittle, and T.J. Yen. 1999. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J Cell Biol. 146:941-54.
Chellappan, S.P., S. Hiebert, M. Mudryj, J.M. Horowitz, and J.R. Nevins. 1991. The E2F transcription factor is a cellular target for the RB protein. Cell. 65:1053-61.
Chesnokov, I., M. Gossen, D. Remus, and M. Botchan. 1999. Assembly of functionally active Drosophila origin recognition complex from recombinant proteins. Genes Dev. 13:1289-96.
Chesnokov, I., D. Remus, and M. Botchan. 2001. Functional analysis of mutant and wild-type Drosophila origin recognition complex. Proc Natl Acad Sci U S A.
98:11997-2002.
Chong, J.P., M.K. Hayashi, M.N. Simon, R.M. Xu, and B. Stillman. 2000. A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase. Proc Natl Acad Sci U S A. 97:1530-5.
Chong, J.P., H.M. Mahbubani, C.Y. Khoo, and J.J. Blow. 1995. Purification of an MCM-containing complex as a component of the DNA replication licensing system. Nature. 375:418-21.
Chong, J.P., P. Thommes, and J.J. Blow. 1996. The role of MCM/P1 proteins in the licensing of DNA replication. Trends Biochem Sci. 21:102-6.
Chung, T.D., F.H. Drake, K.B. Tan, S.R. Per, S.T. Crooke, and C.K. Mirabelli. 1989.
Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc Natl Acad Sci U S A.
86:9431-5.
Clarke, D.J., and J.F. Gimenez-Abian. 2000. Checkpoints controlling mitosis.
Bioessays. 22:351-63.
Clyne, R.K., and T.J. Kelly. 1995. Genetic analysis of an ARS element from the fission yeast Schizosaccharomyces pombe. Embo J. 14:6348-57.
Cocker, J.H., S. Piatti, C. Santocanale, K. Nasmyth, and J.F. Diffley. 1996. An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast. Nature. 379:180-2.
Coleman, T.R., P.B. Carpenter, and W.G. Dunphy. 1996. The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell. 87:53-63.
Connelly, M.A., H. Zhang, J. Kieleczawa, and C.W. Anderson. 1996. Alternate splice-site utilization in the gene for the catalytic subunit of the DNA-activated protein kinase, DNA-PKcs. Gene. 175:271-3.
Connelly, M.A., H. Zhang, J. Kieleczawa, and C.W. Anderson. 1998. The promoters for human DNA-PKcs (PRKDC) and MCM4: divergently transcribed genes located at chromosome 8 band q11. Genomics. 47:71-83.
Cook, P.R. 1999. The organization of replication and transcription. Science.
284:1790-5.
Courey, A.J., and R. Tjian. 1988. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif.
Cell. 55:887-98.
Crane-Robinson, C., F.A. Myers, T.R. Hebbes, A.L. Clayton, and A.W. Thorne. 1999.
Chromatin immunoprecipitation assays in acetylation mapping of higher eukaryotes. Methods Enzymol. 304:533-47.
Creaser, P.C., D.A. D'Argenio, and T. Williams. 1996. Comparative and functional analysis of the AP2 promoter indicates that conserved octamer and initiator elements are critical for activity. Nucleic Acids Res. 24:2597-605.
Critchlow, S.E., R.P. Bowater, and S.P. Jackson. 1997. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr Biol.
7:588-98.
Dalton, S. 1992. Cell cycle regulation of the human cdc2 gene. Embo J. 11:1797-804.
Dalton, S., and L. Whitbread. 1995. Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast. Proc Natl Acad Sci U S A. 92:2514-8.
Datta, P.K., P. Raychaudhuri, and S. Bagchi. 1995. Association of p107 with Sp1:
genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription. Mol Cell Biol. 15:5444-52.
de Stanchina, E., D. Gabellini, P. Norio, M. Giacca, F.A. Peverali, S. Riva, A. Falaschi, and G. Biamonti. 2000. Selection of homeotic proteins for binding to a human DNA replication origin. J Mol Biol. 299:667-80.
Delgado, S., M. Gomez, A. Bird, and F. Antequera. 1998. Initiation of DNA replication at CpG islands in mammalian chromosomes. Embo J. 17:2426-35.
Dennig, J., M. Beato, and G. Suske. 1996. An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. Embo J. 15:5659-67.
DePamphilis, M.L. 1993. Eukaryotic DNA replication: anatomy of an origin. Annu Rev Biochem. 62:29-63.
DePamphilis, M.L. 1996. DNA replication in eukaryotic cells. Cold Spring Harbor Laboratory Press, Plainview, New York. xiii, 1058 pp.
DePamphilis, M.L. 1997. Identification of replication origins in eukaryotic cells. San Diego: Academic Press.
DePamphilis, M.L. 1999. Replication origins in metazoan chromosomes: fact or fiction? Bioessays. 21:5-16.
Detweiler, C.S., and J.J. Li. 1997. Cdc6p establishes and maintains a state of replication competence during G1 phase. J Cell Sci. 110:753-63.
Dhar, S.K., L. Delmolino, and A. Dutta. 2001. Architecture of the human origin recognition complex. J Biol Chem. 276:29067-71.
Dhar, S.K., and A. Dutta. 2000. Identification and characterization of the human ORC6 homolog. J Biol Chem. 275:34983-8.
Diffley, J.F., and J.H. Cocker. 1992. Protein-DNA interactions at a yeast replication origin. Nature. 357:169-72.
Diffley, J.F., J.H. Cocker, S.J. Dowell, and A. Rowley. 1994. Two steps in the assembly of complexes at yeast replication origins in vivo. Cell. 78:303-16.
Diffley, J.F., and B. Stillman. 1988. Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer. Proc Natl Acad Sci U S A. 85:2120-4.
Dijkwel, P.A., and J.L. Hamlin. 1988. Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.
Mol Cell Biol. 8:5398-409.
Dijkwel, P.A., and J.L. Hamlin. 1992. Initiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine. Mol Cell Biol. 12:3715-22.
Dijkwel, P.A., J.P. Vaughn, and J.L. Hamlin. 1991. Mapping of replication initiation sites in mammalian genomes by two- dimensional gel analysis:
stabilization and enrichment of replication intermediates by isolation on the nuclear matrix. Mol Cell Biol. 11:3850-9.
Dimitrova, D.S., M. Giacca, F. Demarchi, G. Biamonti, S. Riva, and A. Falaschi. 1996.
In vivo protein-DNA interactions at human DNA replication origin. Proc Natl Acad Sci U S A. 93:1498-503.
Discher, D.J., N.H. Bishopric, X. Wu, C.A. Peterson, and K.A. Webster. 1998.
Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element. J Biol Chem.
273:26087-93.
Donovan, S., J. Harwood, L.S. Drury, and J.F. Diffley. 1997. Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.
Proc Natl Acad Sci U S A. 94:5611-6.
Dubey, D.D., J. Zhu, D.L. Carlson, K. Sharma, and J.A. Huberman. 1994. Three ARS elements contribute to the ura4 replication origin region in the fission yeast, Schizosaccharomyces pombe. Embo J. 13:3638-47.
Durocher, D., and S.P. Jackson. 2001. DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Curr Opin Cell Biol. 13:225-31.
Dynan, W.S. 1986. Promoters for housekeeping genes. Trends Genet. 2:196-197.
Dynan, W.S. 1987. DNase I footprinting as an assay for mammalian gene regulatory proteins. Plenum Press, New York.
Dynlacht, B.D., K. Moberg, J.A. Lees, E. Harlow, and L. Zhu. 1997. Specific regulation of E2F family members by cyclin-dependent kinases. Mol Cell Biol. 17:3867-75.
Dyson, N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev.
12:2245-62.
Dyson, N., P.M. Howley, K. Munger, and E. Harlow. 1989. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.
Science. 243:934-7.
el-Deiry, W.S., T. Tokino, V.E. Velculescu, D.B. Levy, R. Parsons, J.M. Trent, D. Lin, W.E. Mercer, K.W. Kinzler, and B. Vogelstein. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell. 75:817-25.
el-Deiry, W.S., T. Tokino, T. Waldman, J.D. Oliner, V.E. Velculescu, M. Burrell, D.E.
Hill, E. Healy, J.L. Rees, S.R. Hamilton, and et al. 1995. Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res.
55:2910-9.
Elledge, S.J., and J.W. Harper. 1994. Cdk inhibitors: on the threshold of checkpoints and development. Curr Opin Cell Biol. 6:847-52.
Elsasser, S., F. Lou, B. Wang, J.L. Campbell, and A. Jong. 1996. Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases. Mol Biol Cell.
7:1723-35.
Emili, A., J. Greenblatt, and C.J. Ingles. 1994. Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein.
Mol Cell Biol. 14:1582-93.
Fackelmayer, F.O., K. Dahm, A. Renz, U. Ramsperger, and A. Richter. 1994.
Nucleic-acid-binding properties of hnRNP-U/SAF-A, a nuclear-matrix protein which binds DNA and RNA in vivo and in vitro. Eur J Biochem. 221:749-57.
Farnham, P.J. 1996. Transcriptional control of cell growth: The E2F gene family.
Current Topics in Microbiology and Immunology. 208.
Findeisen, M., M. El-Denary, T. Kapitza, R. Graf, and U. Strausfeld. 1999. Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. Eur J Biochem. 264:415-26.
Finnie, N.J., T.M. Gottlieb, T. Blunt, P.A. Jeggo, and S.P. Jackson. 1995. DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc Natl Acad Sci U S A. 92:320-4.
Flores-Rozas, H., Z. Kelman, F.B. Dean, Z.Q. Pan, J.W. Harper, S.J. Elledge, M.
O'Donnell, and J. Hurwitz. 1994. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A. 91:8655-9.
Fox, C.A., S. Loo, A. Dillin, and J. Rine. 1995. The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication.
Genes Dev. 9:911-24.
Fox, C.A., S. Loo, D.H. Rivier, M.A. Foss, and J. Rine. 1993. A transcriptional silencer as a specialized origin of replication that establishes functional domains of chromatin. Cold Spring Harb Symp Quant Biol. 58:443-55.
Francon, P., D. Maiorano, and M. Mechali. 1999. Initiation of DNA replication in eukaryotes: questioning the origin. FEBS Lett. 452:87-91.
Fujita, M., T. Kiyono, Y. Hayashi, and M. Ishibashi. 1997. In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. J Biol Chem. 272:10928-35.
Gardiner, K., and R.J. Mural. 1995. Getting the message: identifying transcribed sequences. Trends Genet. 11:77-9.
Gasser, S.M., B.B. Amati, M.E. Cardenas, and J.F. Hofmann. 1989. Studies on scaffold attachment sites and their relation to genome function. Int Rev Cytol. 119:57-96.
Gaubatz, S., A. Imhof, R. Dosch, O. Werner, P. Mitchell, R. Buettner, and M. Eilers.
1995. Transcriptional activation by Myc is under negative control by the transcription factor AP-2. Embo J. 14:1508-19.
Gaubatz, S., J.G. Wood, and D.M. Livingston. 1998. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc Natl Acad Sci U S A. 95:9190-5.
Gavin, K.A., M. Hidaka, and B. Stillman. 1995. Conserved initiator proteins in eukaryotes. Science. 270:1667-71.
Geraghty, D.S., M. Ding, N.H. Heintz, and D.S. Pederson. 2000. Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant. J Biol Chem. 275:18011-21.
Getts, R.C., and T.D. Stamato. 1994. Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant. J Biol Chem.
269:15981-4.
Giacca, M., C. Pelizon, and A. Falaschi. 1997. Mapping replication origins by quantifying relative abundance of nascent DNA strands using competitive polymerase chain reaction. Methods. 13:301-12.
Giacca, M., L. Zentilin, P. Norio, S. Diviacco, D. Dimitrova, G. Contreas, G. Biamonti, G. Perini, F. Weighardt, S. Riva, and et al. 1994. Fine mapping of a replication origin of human DNA. Proc Natl Acad Sci U S A. 91:7119-23.
Gibson, S.I., R.T. Surosky, and B.K. Tye. 1990. The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication. Mol Cell Biol. 10:5707-20.
Gilbert, D.M. 2001. Making sense of eukaryotic DNA replication origins. Science.
294:96-100.
Gilley, D., H. Tanaka, M.P. Hande, A. Kurimasa, G.C. Li, M. Oshimura, and D.J.
Chen. 2001. DNA-PKcs is critical for telomere capping. Proc Natl Acad Sci U S A. 98:15084-8.
Gohring, F., and F.O. Fackelmayer. 1997. The scaffold/matrix attachment region binding protein hnRNP-U (SAF-A) is directly bound to chromosomal DNA in vivo: a chemical cross-linking study. Biochemistry. 36:8276-83.
Gottlieb, T.M., and S.P. Jackson. 1993. The DNA-dependent protein kinase:
requirement for DNA ends and association with Ku antigen. Cell. 72:131-42.
Grallert, B., and P. Nurse. 1996. The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase. Genes Dev. 10:2644-54.
Grana, X., and E.P. Reddy. 1995. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene. 11:211-9.
Gu, Y., S. Jin, Y. Gao, D.T. Weaver, and F.W. Alt. 1997. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci U S A. 94:8076-81.
Gu, Y., C.W. Turck, and D.O. Morgan. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature. 366:707-10.
Guggenheimer, R.A., B.W. Stillman, K. Nagata, F. Tamanoi, and J. Hurwitz. 1984.
DNA sequences required for the in vitro replication of adenovirus DNA. Proc Natl Acad Sci U S A. 81:3069-73.
Guo, Z.S., and M.L. DePamphilis. 1992. Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication. Mol Cell Biol.
12:2514-24.
Guo, Z.S., C. Gutierrez, U. Heine, J.M. Sogo, and M.L. Depamphilis. 1989. Origin auxiliary sequences can facilitate initiation of simian virus 40 DNA replication in vitro as they do in vivo. Mol Cell Biol. 9:3593-602.
Hagen, G., J. Dennig, A. Preiss, M. Beato, and G. Suske. 1995. Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3. J Biol Chem. 270:24989-94.
Hagen, G., S. Muller, M. Beato, and G. Suske. 1992. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res. 20:5519-25.
Hagen, G., S. Muller, M. Beato, and G. Suske. 1994. Sp1-mediated transcriptional activation is repressed by Sp3. Embo J. 13:3843-51.
Hand, R. 1978. Eucaryotic DNA: organization of the genome for replication. Cell.
15:317-25.
Hardwick, K.G., and A.W. Murray. 1995. Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol. 131:709-20.
Hardwick, K.G., E. Weiss, F.C. Luca, M. Winey, and A.W. Murray. 1996. Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science. 273:953-6.
Hardy, C.F. 1997. Identification of Cdc45p, an essential factor required for DNA replication. Gene. 187:239-46.
Harlow, E., Lane, D.P. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press.
Harper, J.W., G.R. Adami, N. Wei, K. Keyomarsi, and S.J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin- dependent kinases. Cell. 75:805-16.
Hartley, K.O., D. Gell, G.C. Smith, H. Zhang, N. Divecha, M.A. Connelly, A. Admon, S.P. Lees-Miller, C.W. Anderson, and S.P. Jackson. 1995. DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell. 82:849-56.
Hassan, A.B., and P.R. Cook. 1993. Visualization of replication sites in unfixed human cells. J Cell Sci. 105:541-50.
Hata, Y., E. Duh, K. Zhang, G.S. Robinson, and L.P. Aiello. 1998. Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence. J Biol Chem. 273:19294-303.
Hateboer, G., R.M. Kerkhoven, A. Shvarts, R. Bernards, and R.L. Beijersbergen.
1996. Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.
Genes Dev. 10:2960-70.
Hateboer, G., A. Wobst, B.O. Petersen, L. Le Cam, E. Vigo, C. Sardet, and K. Helin.
1998. Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F. Mol Cell Biol. 18:6679-97.
Hatton, K.S., V. Dhar, E.H. Brown, M.A. Iqbal, S. Stuart, V.T. Didamo, and C.L.
Schildkraut. 1988. Replication program of active and inactive multigene families in mammalian cells. Mol Cell Biol. 8:2149-58.
Heiland, S. 1996. Zur transkriptionellen Regulation des menschlichen Typ-I-DNA-Topoisomerase Gens. Dissertation, Universität Konstanz.
Heiland, S. 1996. Zur transkriptionellen Regulation des menschlichen Typ-I-DNA-Topoisomerase Gens. Dissertation, Universität Konstanz.