New Cycloartane-type Triterpenoids from Artocarpus nobilis
Shamsulhaq Zahida, Athar Ataa, and Radhika Samarasekerab
aDepartment of Chemistry, The University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, Canada R3B 2E9
bNatural Products Development Group, Industrial Technology Institute, Colombo-7, Sri Lanka Reprint requests to Prof. Dr. Athar Ata. Fax (204) 775-2114. E-mail: a.ata@uwinnipeg.ca Z. Naturforsch.2007,62b,280 – 284; received July 25, 2006
Recent phytochemical studies on the ethanolic extract ofArtocarpus nobilis, collected from Sri Lanka, have resulted in the isolation of two new cycloartane-type triterpenoids, artocarpuate A (1) and artocarpuate B (2). Structures of these new compounds were established with the aid of extensive NMR spectroscopic studies. Compounds1and2were found to exhibit weak acetylcholinesterase inhibitory activity.
Key words: Artocarpus nobilis, Acetylcholinesterase, Cycloartane-type Triterpenoids