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New Guaianolide-Type Sesquiterpene Lactones from Inula verbascifolia

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New Guaianolide-Type Sesquiterpene Lactones from Inula verbascifolia

Abou El-Hamd H. Mohameda,*, Hosam-Eldin H. Mahmoudb,

Fathy F. Abdellatifc, Yousif S. Mohamedc, the late Ahmed A. Ahmedc, and Shinji Ohtad

a Chemistry Department, Faculty of Science, Aswan University, Aswan, Egypt.

Fax: +973480450. E-mail: abouhassan68@yahoo.com

b Medical Chemistry Department, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia

c Chemistry Department, Faculty of Science, El-Minia University, El-Minia, Egypt

d Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga 526-0829, Japan

* Author for correspondence and reprint requests

Z. Naturforsch. 68 c, 175 − 180 (2013); received December 12, 2012/May 8, 2013

The aerial parts of Inula verbascifolia afforded two new guaianolide-type sesquiterpene lactones. Their structures were determined by spectroscopic methods (IR, MS, 1H NMR,

13C NMR, DEPT, 1H-1H COSY, HMQC, and HMBC).

Key words: Asteraceae, Inula, Sesquiterpene Lactones

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