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Two New Clerodane-type Diterpenoids from Gomphostemma microdon Rong-Ting Zhang

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Two New Clerodane-type Diterpenoids from Gomphostemma microdon

Rong-Ting Zhanga,b, Tao Fenga,b, Xiang-Hai Caia, and Xiao-Dong Luoa

aState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650204, P. R. China

bGraduate Schoolof Chinese Academy of Sciences, Beijing 100039, P. R. China

Reprint requests to Prof. Dr. Xiao-Dong Luo. Fax: +86-871-5150227. E-mail: xdluo@mail.kib.ac.cn Z. Naturforsch.2009,64b,443 – 446; received November 30, 2008

Two new clerodane-type diterpenoids, along with seven known compounds have been isolated from the aerialparts ofGomphostemma microdon. All structures were established on the basis of spectroscopic analyses, including application of MS, UV, IR, 1D and 2D NMR techniques.

Key words: Gomphostemma microdon, Clerodane Diterpenoids,MicrodonA,MicrodonB Diterpenes

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b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204,

As part of our continuing research on novel biologically active com- pounds from Chinese traditional medicine, two new clerodane diterpenes and four known compounds were isolated

Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071,

b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming, Yunnan 650204, China.

a Institute of Botany, Jiangsu Province & Chinese Academy of Sciences, Jiangsu Province Key Laboratory for Plant Ex-Situ Conservation (Nanjing Botanical Garden, Mem..

b Key Laboratory of Excited State Processes, Changchun Institute of Optics Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033,

The authors are grateful to the National Natural Sci- ence Foundation of China (C30670214), National Basic Resarch Program of China (973 Program 2009CB522300) and the Chinese Academy

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China. b Graduate School of