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Supplementary Appendix 3 Dichotomized neurocognitive outcomes in ivermectin-naïve children

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Supplementary Appendix 3

Dichotomized neurocognitive outcomes in ivermectin-naïve children

Neurocognitive tests and outcomes Ov16-negative (controls)

n = 24

Ov16-positive (cases)

n = 18

P-value*

Pegboard, dominant hand Normal: n (%) 23 (95.8%) 18 (100%) 1.000 Below normal: n (%) 1 (4.2%) 0 (0%)

Pegboard, non-dominant hand

Normal: n (%) 23 (95.8%) 18 (100%) 1.000

Below normal: n (%) 1 (4.2%) 0 (0%)

Pegboard, both hands Normal: n (%) 23 (95.8%) 18 (100%) 1.000 Below normal: n (%) 1 (4.2%) 0 (0%)

Digit span forward Normal: n (%) 24 (100%) 18 (100%) 1.000

Below normal: n (%) 0 (0%) 0 (0%)

Digit span backward Normal: n (%) 24 (100%) 18 (100%) 1.000

Below normal: n (%) 0 (0%) 0 (0%)

Hand movements Normal: n (%) 24 (100%) 17 (94.4%) 0.429

Below normal: n (%) 0 (0%) 1 (5.6%)

Semantic verbal fluency Normal: n (%) 23 (95.8%) 17 (94.4%) 1.000 Below normal: n (%) 1 (4.2%) 1 (5.6%)

Mini-mental state exam Normal: n (%) 23 (95.8%) 18 (100%) 1.000 Below normal: n (%) 1 (4.2%) 0 (0%)

International HIV Dementia Scale

Normal: n (%) 22 (91.7%) 18 (100%) 0.498

Below normal: n (%) 2 (8.3%) 0 (0%)

*Yates corrected Chi-squared test

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