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Supplementary Table 1. Patient and tumor characteristics for cases with single- fraction Re-SRS

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Supplementary Table 1. Patient and tumor characteristics for cases with single- fraction Re-SRS

Total %

Patients 23

Lesions 24

Gender Male 10 43.5

Female 13 56.5

Age 1st SRS Median (range) in years 64.3 (41.8-80.4)

Age Re-SRS Median (range) in years 65.0 (42.8-81.3)

Karnofsky-Index 1st SRS

Median (range) in % 90 (60-100)

Karnofsky-Index

Re-SRS Median (range) in % 90 (60-100)

Primary tumor

(per lesion) NSCLC 7 29.2

Melanoma 5 20.8

Breast cancer 9 37.5

Colorectal cancer 1 4.2

Other 2 8.3

Localization of recurrent lesions

Frontal 8 33.3

Temporal 1 4.2

Parietal 5 20.8

Thalamus/mesencephalo

n 2 8.3

Cerebellum 7 29.2

Brainstem 1 4.2

Time intervals between SRS- series

Median (range) in months 12.7 (4.1-88.2)

Abbreviations: SRS: stereotactic radiosurgery, NSCLC: non-small cellular lung

cancer

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