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Online Resource 1. The final diagnoses of patients with “indeterminate” and “atypical” chest CT findings

Chest CT findings

Indeterminate Atypical

- Single, peripheral GGO (with or without consolidation);

- Single, round GGO (with or without consolidation)

- Diffuse, multifocal, perihilar or unilateral GGOs with or without consolidation;

- Few, very small GGOs with a non- rounded and non-peripheral distribution

- Isolated segmental or lobar consolidation without GGO;

- Centrilobular small nodules (“tree in bud”);

- Lung cavitation;

- Smooth interlobular septal thickening with pleural effusion

Final diagnoses Count Percent (%)* Count Percent (%)* Count Percent (%)*

- Covid-19 64 87.7 13 14.4 - -

- Lobar-segmental pneumonia - - - - 54 35.1

- Other pneumonias 7 9.6 40 44.4 - -

- Alveolar edema - - 22 24.4 - -

- Interstitial edema - - - - 45 29.2

- Aspiration pneumonia - - 6 6.7 1 0.6

- Alveolar haemorrhage 1 1.4 3 3.3 - -

- Small airway disease - - 2 2.2 51 33.1

- Pulmonary infarct 1 1.4

- Radiation pneumonitis - - 1 1.1 - -

- Connective tissue disease - - 1 1.1 - -

- Hypersensitivity pneumonitis - - 1 1.1 - -

- Lung cancer - - 1 1.1 3 1.9

CT: Computed tomography, GGO: Ground-glass opacity, * Column percentage

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4 Department of Orthopaedic Surgery, Sports Orthopedic Research Center – Copenhagen (SORC-C), Amager-Hvidovre Hospital, Faculty of Health Sciences, Copenhagen University,