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Effect of Wnt5a on drug resistance in estrogen receptor-positive breast cancer

Ai Amioka1), Takayuki Kadoya1), Satoshi Sueoka1), Yoshie Kobayashi1), Shinsuke Sasada1), Akiko Emi1), Norio Masumoto1), Masaoki Ito1), Koh Nakayama2), Morihito Okada1)

1) Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima 734-8551, Japan

2) Oxygen Biology Laboratory, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113- 8510, Japan

Corresponding author

Takayuki Kadoya, M.D, Ph.D Email:takayukikadoya@gmail.com Tel.:+81-082-257-5869

Fax:+81-082-256-7109

(2)

Interrelationship and expression levels of the genes shown in Online Resource 4

Genes were arranged in a circle and their interrelationships were characterized with colored lines using CytoScape (Version 3.8.2, http://cytoscape.org). The gene expression levels after conversion to logarithm are color-coded; from green to red for low or highly expressed genes, respectively. Some genes whose expression was not estimated in DNA microarray analysis are shown as gray circles. The colored lines represent the interrelationships between the connected genes.

Online Resource 5

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