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Online Resource 12. Summary of safety (safety set)

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Graefe's Archive for Clinical and Experimental Ophthalmology

Impact on visual acuity and psychological outcomes of ranibizumab and subsequent treatment for diabetic macular oedema in Japan (MERCURY)

Taiji Sakamoto, Masahiko Shimura, Shigehiko Kitano, Masahito Ohji, Yuichiro Ogura, Hidetoshi Yamashita, Makoto Suzaki, Kimie Mori, Yohei Ohashi, Poh Sin Yap, Takeumi Kaneko, Tatsuro Ishibashi, for the MERCURY Study Group

Corresponding author:

Taiji Sakamoto

Department of Ophthalmology, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890- 8544, Japan

Tel: +81 99-275-5402 Fax: +81 99-265-4894

Email: tsakamot@m3.kufm.kagoshima-u.ac.jp

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Online Resource 12. Summary of safety (safety set)

Events, n (%)

Safety Set N = 209

Death 3 (1.4)

AE

Ocular AE 57 (27.3)

Non-ocular AE 89 (42.6)

SAE

Ocular SAE 19 (9.1)

Non-ocular SAE 29 (13.9)

AE leading to discontinuation of study drug

Ocular AE 0

Non-ocular AE 3 (1.4)

SAE leading to discontinuation of study drug

Ocular SAE 0

Non-ocular SAE 3 (1.4)

AE, adverse event; SAE, serious adverse event.

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