CURRICULUM VITAE
Personalien Prof. Dr. med. Beat Müller Geburt 15. März 1965 in Bern
Heimatort Basel-Stadt und Bubendorf (BL), Schweizer Bürger Zivilstand verheiratet mit Beatrice Ackermann Müller (seit 1991) 3 Kinder: Laura *1994, Jonas *1996, Lars *1998
Privatadresse Bruderholzallee 196, CH-4059 Basel
T / M: +4179 480 7989; E: happy.mueller@unibas.ch
Geschäftsadresse Medizinische Universitätsklinik, Kantonsspital KSA AG, Tellstrasse H7, CH 5001 Aarau
T / F: +4162 838 6818 / 6945; E: beat.mueller@ksa.ch B. Ausbildung & Berufliche Erfahrung
1972 – 1978 Primar- und Sekundarschule, Kehrsatz, Bern
1978 – 1984 Gymnasium Bern-Kirchenfeld, Matura Typus E (Wirtschaft) 1984 – 1990 Medizinstudium, Universität Bern
1989 – 1990 Wahlstudienjahr, u.a. Elim Hospital, Gazankulu, Republic of South Africa (RSA)
12. Dez 1990 Schweizerisches Staatsexamen & Dissertation: “In Presseorganen angepriesene Schlankheitskuren” (Proff. M.P. König, U. Bürgi, Bern) 8. Jan 1991 US Medical Exam (FMGEMS I&II, TOEFL), ECFMG, Philadelphia, PA, USA
Feb – Okt 1991 Militärdienst, Leutnant abverdienen als Schularzt, Oberleutnant (a.D. 2000) Nov 1991 – Feb 1993 Klinisch-wissenschaftlicher Assistenzarzt, Abt. für Endokrinologie,
Dept. Innere Medizin, Universitätsspital Basel (Prof. J.J. Staub)
Apr 1993 – Mär 1995 Assistenzarzt, Medizinische Universitätsklinik, Kantonsspital Liestal (BL) Prof. A. Rosenmund (Allgemeine Innere & Notfall Medizin, Intensivmedizin) Apr 1995 – Jul 1996 Assistenzarzt, Dept. Innere Medizin, Universitätsspital Basel,
Prof. J. A. Schifferli (Allgemeine Innere Medizin, Intensivmedizin, Nephrologie) Aug 1996 Facharzt Innere Medizin (FMH)
Aug 1996 – Mar 1997 Oberarzt, Dept. Innere Medizin, Universitätsspital Basel, Prof. J. A. Schifferli (Allgemeine Innere & Notfall-Medizin, Intensivmedizin)
Jul 1997 – Sep 1999 Postdoctoral Research Fellowship, Lab of Molecular Endocrinology (Prof. J.F.
Habener), Harvard University, Massachusetts General Hospital, Boston, USA Okt 1999 – Sep 2000 Weiterbildungsassistent, Abt. Endokrinologie, Diabetologie and klinische
Ernährung
Universitätsspital Basel (USB), Proff. U. Keller & J.J. Staub
Okt 2000 – Aug 2001 Oberarzt, 80% Dept. Innere Medizin (Prof. A. P. Perruchoud), 20% Klinik für Endokrinologie, Diabetologie und klinische Ernährung (Proff. U. Keller, J.J.
Staub), USB
Sep 2001 Facharzt Endokrinologie und Diabetologie (FMH)
8. Nov 2002 Venia docendi für Innere Medizin (Postdoctoral Thesis, Habilitation) 8. Dez 2004 Titular Professur für Innere Medizin & Endokrinologie
Sep 2001 – Mar 2008 Stv. Chefarzt, Klinik für Endokrinologie, Diabetologie & klinische Ernährung, Bereich Medizin, Universitätsspital Basel
Apr 2008 – Bereichsleiter Medizin & Direktor / Leiter Medizinische Klinik, Kantonsspital Aarau AG
Apr 2008 – Dez 2018 Chefarzt Abt. für Allgemeine Innere und Notfallmedizin, Kantonsspital Aarau AG
Jan 2009 – Chefarzt Abt. Endokrinologie, Diabetologie, Metabolismus, Kantonsspital Aarau AG
Mai 2010 – Ordinarius für Medizin & Endokrinologie („Argovia Professor für Outcome Forschung“) Leiter Universitätsklink der Medizinischen Fakultät Basel, Kantonsspital Aarau AG
Jun. 2010 – Verwaltungsrat (Governing Board) Argomed AG, Lenzburg (AG) Jul. 2011 – Dez 2014 Leiter SIC (Stroke Unit, Intermediate Care, Coronary Care Unit)
Aug. 2012 – Jun 2018 Mitglied der Geschäftsleitung (Executive Board) Kantonsspital Aarau AG Jan 2016 – Verwaltungsrat (Governing Board) Psychiatrie Basel-Land (PBL), Liestal
(BL)
Nov 2019 – Nov 2022 Präsident Schweizerische Gesellschaft Endokrinologie & Diabetologie (SGED/SSED)C.
Berufliche Weiterbildung Allgemeine Innere Medizin
Swiss Society of Internal Medicine (SGIM). annually 1992 – to date (interrupted)
European Society of Clinical Investigation (ESCI), Ann. Meeting, Heidelberg (D) 1993; Interlaken, 1996
medART, Basel 2005, 2006, 2007, 2008, 2011
American College of Physician (ACP) Course of Internal Medicine 2009 Philadelphia (PA), 2014 Orlando (FL)
Endokrinologie, Diabetes und Metabolismus
Swiss Society for Endocrinology & Diabetology (SGED). Ann. Meetings 1991 – to date (interrupted)
European Congress of Endocrinology. Ann. Meeting, Geneva 1995; Lyon (F) 2003, Glasgow (UK) 2006
European Certificate in Andrology, Univ. of Basel, Strasbourg and Freiburg i.Br., 1991 & 1992
Endocrine Society (Endo, USA), Clinical Endocrinology Update, Boston, MA 1998; Ann. Meeting, New Orleans, LO, 1998; San Diego, CA 1999; Toronto (CDN) 2000; Denver, CO, 2001; San Francisco, CA 2002 & 2013; Philadelphia, PA, 2003; New Orleans, LO, 2004; San Diego, CA, 2005, Boston, MA, 2006 & 2011
Int. Congress of Endocrinology (ICE), Nizza (F) 1992; San Francisco, CA (USA), 1996; Lisboa (P) 2004
European Neuroendocrine Association (ENEA) Ann. Meeting, Munich (D) 02; Napoli (I) 04, Athens (Gr) 06
Growth Factors in Endocrinology, Budapest (Hu) 2002; Prag (Cz) 2003; La Valetta (Ma) 2004
Osteoporosis & Bone Densitometry, Olten, 2001, Certificate (ISCD, SVGO, IOF), Basel 2002
Endocrine Tele-Surgery, 4th Int. Post-Graduate Course, Strasbourg, (F) 2001
American Diabetes Association (ADA, USA), Ann. Meeting, Boston, MA 1997; San Francisco, CA 2002
International Diabetes Federation (IDF) Cape Town 2006, Dubai 2011
Immunology of Diabetes, Islet & Pancreas Transplants DEM Foundation, Orvieto (I) 1995
European Association for the Study of Diabetes, 2nd Post-EASD-Symposium, Zürich 1997
European Society for Parenteral and Enteral Nutrition (ESPEN), Nice (F), 2010
Pneumologie, Intensiv- & Notfallmedizin
Society of Critical Care Medicine (SCCM), Toronto (CDN), 1998, San Francisco, CA, 2006
European Society of Intensive Care Medicine (ESCIM), Ann. Meeting, Geneva, 2001; Berlin (D) 2004
Intern. Symposium on Intensive Care and Emergency Medicine (ISICEM) Ann. Meeting, Brussels (B), 2001, 2003, 2004, 2005, 2006, 2007, 2009, 2010, 2011, 2012
Sepsis und Multiorgandysfunktion, Int. Symposium, Weimar (D) 2001, 2005, 2007, 2009, 2011
Ann Meetings Am. Thoracic Society (ATS, USA) 2004 & Am. College of Emergency Physicians 2006
Société de Réanimation de Langue Française (SRLF) Paris (F) 2005, 2008, 2010, 2012
Infektiologie
European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), München 2007, Wien 2010
Interscience Conferences on Antimicrobial Agents and Chemotherapy (ICAAC, USA), Ann Meetings, San Diego, CA, 1998; San Francisco, CA 1999; Chicago, IL 2003 & 2007; Washington, DC 2004 & 2005
Klinisch-wissenschaftliche & experimentelle Medizin
Current Techniques in Molecular Biology, Harvard Medical School, Boston, MA (USA) 1997
Good Clinical Practice (GCP), Aarau, 2010 (Updates 2017, 2019); CGP Course for Supervisiors, USB, 2014
Spital-Management (“Hospital Governance”)
HADmedical Grundkurs: Verhalten, Führung & Teammanagement. Zürich, 2000
Finanzen im Spital – Kurs für Nichfinanzfachleute in ärzlicher Kaderposition, Bern, 2007
Essential Competencies for Leadership. American College of Physicians (ACP) Philadelphia (PA) 2009
Management Lehrgang “Prozessoptimierung im Krankenhaus”, Euroforum 12.3. – 30.4.2010
„New Hospital Governance“ Führung & Aufsicht von Spitäler Prof. M. Hilb – Uni St. Gallen, 21.2.2011
Strukturgruppe „Reorganisation Führungsstrukturen“ Kantonsspital Aarau AG 2011 – 12
The Art of Leadership. American College of Physicians (ACP), Orlando (FL), 8.4 – 9.4.2014
Executive Circle, J. Rüegg-Sturm, Hochschule St. Gallen (HSG), 2014 –II. AKTUELLE FÜHRUNGSFUNKTIONEN & KLINISCHE SCHWERPUNKTE
I. Bereichsleiter MedizinDer Bereich Medizin besteht neben der Medizinischen Universitätsklinik aus den Kliniken Neurologie und Rheumatologie und umfasst rund 200 Betten, über 650 Stellen mit rund 900 Mitarbeitenden. So wurden 2017 über 8500 stationäre Akutpatienten betreut und über 100'000 ambulante Sprechstunden an Patienten erbracht.
Meine Verantwortlichkeiten & Aktivitäten gliedern wie folgt.
* Budget, Strategie, Führung und Koordination des ganzen Bereiches, gemeinsam mit der Bereichsleitung Pflege Fr. Susanne Schirlo. Finanzielles und medizinisches Bereichsreporting.
* Einbringen von medizinischem Fachwissen, ärztlichen Sachverstand und Expertise über klinische Patientenprozesse in operative & taktische Entscheidungen von Kommissionen &
Geschäftsleitung.
* Arbeit in Kommissionen. Zusammenarbeit mit Geschäftsleitung, Verwaltungsrat und politischen Behörden des Kantons
* Zusammenarbeit & Koordination mit den anderen Bereichen des Spitals, namentlich
interdisziplinäres Notfallzentrum, Chirurgie, Frauen und Kinder, Perioperative Medizin sowie zentrale medizinische Dienste
* Jährliche Zielvereinbarungen mit allen Chefärzten der Medizinischen Universitätsklinik und Klinik für Neurologie
* Konzeption, Aufbau und Betrieb einer interdisziplinären Stroke Unit, Intermediate Care Station und Coronary Care Unit (SIC) in Zusammenarbeit mit der Klinik für Neurologie und der Abteilung Kardiologie
* Zuweiserpflege und intensive Zusammenarbeit mit regionalen Hausärzten und Spitäler (Zofingen, Menziken, Laufenburg, Rheinfelden, Baden, Muri). Dies unterstützt durch mein
Verwaltungsratsmandat der Argomed AG.
II. Leiter Medizinische Universitätsklinik & Ordinarius Innere Medizin („Argovia- Professur“)
Die Klinik besteht aus den Abteilungen für Allg. Innere & Notfall-Medizin (inkl. Fachbereiche Psychosomatik, Pharmakologie), Angiologie, Dermatologie / Allergologie, Endokrinologie /
Diabetologie / Metabolismus, Gastroenterologie & Hepatologie, Hämatologie & Transfusionsmedizin, Onkologie, Infektiologie & Spitalhygiene, Intensivmedizin, Kardiologie, Nephrologie & Dialyse &
Transplantation, und Pneumologie & Schlafmedizin.
Meine Aktivitäten gliedern wie folgt.
* Sicherung einer hochstehenden, bedarfsgerechten interdisziplinären Behandlung und interprofessionellen Betreuung von hospitalisierten Patienten in rund 220 Betten unter
Respektierung und Förderung der Fachkompetenz aller Fachdisziplinen. Die Patienten werden bei (Notfall-)Aufnahme den einzelnen Fach-gebieten gemäss der im Vordergrund stehenden
medizinischen Problematik zugeteilt und von Assistenten & Oberärzten der Allgemeinen Inneren Medizin gemeinsam mit und unter Führung durch die Chefärzten betreut.
* Forschungsstratege der Klinik: Leiter interprofessionelles “OPTIMA-TRIAGE-InHospiTOOL”- Projekte. “Antibiotic-Stewardship” bei Atemwegsinfektionen, EFFORT-Studie zur Malnutrition im Spital (Prof. P. Schütz)
* Ausarbeitung und Implementation von klinikrelevanten Betriebsnormen und Therapieempfehlungen
* Stellen- und Bettendisposition für Bettenstation, medizinische Intensivstation und internistischer Notfalldienst.
* Tägliche Betreuung aller Zusatzversicherten Patienten in Allgemeiner Innerer & Notfall-Medizin (2008-18)
* Ärztlich-Medizinischer Führungs- & Weiterbildungsverantwortlicher für das Zentrum für Notfallmedizin (ZNM)
* Wöchentliche Chefarztvisiten bei grundversicherten stationären allgemein-internistischen Patienten
* Leitung des medizinischen Ambulatoriums mit internistischer Abklärung von rund 550 Patienten pa.
* Jährliche Zielvereinbarungen & Führung aller Chefärzte der 12 Abteilungen.
* Rekrutierung, Supervision, Qualifikation, Organisation und Sicherung der Aus-, Weiter- und Fortbildungbildung sowie Mentoring der z.Zt. 43 Assistenz- und 18 Oberärzte der Allgemeinen Inneren und Notfallmedizin.
III. Chefarzt Abt. Endokrinologie, Diabetologie & Metabolismus & Ordinarius Endokrinologie
* Tägliche Betreuung & Fachverantwortung ambulanter & stationärer Patienten des gesamten Fachgebietes
* Konzeption, Aufbau & Betrieb. interdisziplinäre Sprechstunden & Tumornachsorgen, Interpretation von diagnostischen Hormontests, Ultraschall & Feinnadelpunktion der Schilddrüse,
Insulintherapien aller Art
* Ausarbeitung und Implementation von Behandlungsrichtlinien und “Guidelines” (“Pocket Guide”, KISIM)
* Initiant & Co-Leitung Endo-Diab-NET™ Aarau-Basel-Luzern mit überregionalem, universitärem Dienstleistungs-, Ausbildungs- & Forschungskonzept, das EndoDiabNET ist eine
Weiterbildungsstätte Kategorie A (3 Jahre)
III. BIBLIOGRAPHIE - PUBLIKATIONSLISTE
Stand 20. Mai 2020
Orchid-ID: 0000-0002-1986-2511 Researcher ID: http://www.researcherid.com/rid/G-2662-2012 Research Gate: >97.5 Percentile H-Index: 76 (71 excl. self-references) Impact Factors (IF): >
3031.7
A. Originalarbeiten in referierten Zeitschriften (“peer reviewed”) IF > 2534.5 1. Exer P., Staub J.J., Zulewski H., Müller B., Kunz M., Huber P. Die Beurteilung der TSH-
Suppression mit einem TSH-Assay der 3. Generation: diagnostische und therapeutische Konsequenzen.
Schweiz Med Wochenschr 1992; 122: 1964-67 IF 1.9
2. Müller B., Abelin Th. Evaluation of weight control programs advertised in the swiss press.
Schweiz Med Wochenschr 1994; 124: 749-58 IF 1.9
3. Müller B., Zulewski H., Huber P., Ratcliffe J.G., Staub J.J. Impaired Action of Thyroid Hormone Associated with Smoking in Women with Hypothyroidism.
New Engl J Med 1995; 333: 964-9 IF 79.3
Editorial: Utiger R.D. Cigarette Smoking and the Thyroid.
New Engl J Med 1995; 333: 1001-2
Award: Prize of the Swiss Society of Internal Medicine (SGIM) 1995
4. Zulewski H., Müller B., Exer P., Miserez A.R., Staub J.J. Estimation of tissue hypothyroidism by a new clinical score: Evaluation of patients with various grades of hypothyroidism and controls.
J Clin Endocrinol Metab 1997; 82: 771-6 IF 6.3
5. Whang K.T., Vath S.D., Nylen E.S., Müller B., Li Q., Tamarkin L., White J.C. Procalcitonin and Pro-inflammatory Cytokine Interactions in Sepsis. Shock 2000; 14: 73-78 IF 2.9 6. Müller B., Becker K.L., Schächinger H., Rickenbacher P.R., Huber P.R., Zimmerli W., Ritz R.
Calcitonin Precursors are Reliable Markers of Sepsis on a Medical Intensive Care Unit.
Crit Care Med 2000; 28: 977-83 IF 6.3
Editorials: - Vincent J.L. Procalcitonin: THE marker of sepsis?
Crit Care Med 2000; 28(4): 1226-7
- Boucher BA. Procalcitonin: Clinical tool or laboratory curiosity?
Crit Care Med 2000; 28(4): 1224-5
Award: 1st Annual Prize for Medical Intensive Care (Krokus Foundation) 2001
7. Müller B., Becker K.L, Kränzlin M., Schächinger H., Huber P.R., Nylèn E.S., Snider R.H., White J.C., Schmidt-Gayk H., Zimmerli W, Ritz R. Disordered calcium homeostasis of sepsis: associated with calcitonin precursors. Europ J Clin Invest 2000; 30: 823-31 IF 3.0 8. Müller B., Tsakiris D., Roth C.B., Guglielmetti M., Staub J.J., Marbet G.A. Haemostatic profile in
patients with subclinical hypothyroidism as a potential risk factor for vascular or thrombotic
disease. Europ J Clin Invest 2001; 31: 131-37 IF 3.0
9. Müller B., White J.C., Nylen E., Snider R.S. Becker K.L., Habener J.F. Ubiquitous expression of the calcitonin-I gene in multiple tissues in response to sepsis.
J Clin Endocrinol Metab 2001; 86 396-404 IF 6.3
10. Zulewski H., Abraham E.J., Gerlach M.J., Daniel P.B., Moritz W., Müller B., Vallejo M., Thomas M.K., Habener J.F. Multipotential Nestin-Positive Stem Cells Isolated from Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes. Diabetes
2001; 50: 521-33 IF 8.3
11. Müller B., Peri G., Doni A., Torri V., Landmann R., Bottazzi B., Mantovani A. Circulating Levels of the long Pentraxin PTX3 correlate with severity of infection in critically ill patients.
Crit Care Med 2001; 29(7): 1404-7 IF 6.3
12. Meier C., Staub J.J., Roth C.B., Guglielmetti M., Kunz M., Miserez A.R., Drewe J., Huber P., Herzog R.,Müller B. TSH-Controlled L-Thyroxine Therapy Reduces Cholesterol Levels and Clinical Symptoms in Subclinical Hypothyroidism: A Double Blind, Placebo-Controlled Trial
(Basel Thyroid Study). J Clin Endocrinol Metab 2001; 86: 4860-4866 IF 6.3 Editorials: - McDermott M.T. and Ridgway E.C. Subclinical Hypothyroidism Is Mild Thyroid
Failure and Should be Treated. J Clin Endocrinol Metab 2001; 86: 4585-4590 - Chu J.W. and Crapo L.M. The Treatment of Subclinical Hypothyroidism Is
Seldom Necessary. J Clin Endocrinol Metab 2001; 86: 4591-4599 Awards: - Best oral presentation Annual Meeting SGIM 2001 (cf. Abstract #48) - Finalist Award of the Endocrine Society & Pharmacia Corporation International Award for Excellence in Published Clinical Research 2002
13. Suarez Domenech V., Nylen E.S., White J.C., Snider R.H., Becker K.L., Landmann R., Müller B.:
Calcitonin gene-related peptide messenger RNA in bacterial sepsis: Postulation of microbial infection-specific response elements (MISRE) within the Calc-I gene promotor.
J Invest Med 2001; 49: 514-21 IF 2.0
14. Martinez J.M., Wagner K.E., Snider R.H., Nylén E.S., Müller B., Sarani B., Becker K.L., White J.C.
Late immunoneutralization of procalcitonin arrests the progression of lethal porcine sepsis.
Surgical Inf 2001; 2: 193-201 (discussion 202-3) IF 1.8 15. Müller B., Peri G., Doni A., Landmann R., Pasqualini F., Mantovani A. High circulating levels of IL-
1 type II decoy receptor in critically ill patients with sepsis: Association of high decoy receptor levels with glucocorticoid administration. J Leukoc Biol 2002; 72: 643-9 IF 5.0 Award: Annual Prize for Medical Intensive Care (Krokus Foundation) 2003
16. Wagner K.E., Martinez J.M., Vath SD, Snider R.S., Nylen E.S., Becker K.L., Müller B., White J.C.
Early Immunoneutralization of Calcitonin Precursors Markedly Attenuates the Adverse Response
to Sepsis in Pigs. Crit Care Med 2002; 30: 2313-21 IF 6.5
17. Berneis K., Staub J.J., Gessler A., Meier C., Girard J. and Müller B. Combined stimulation of ACTH and Compound-S by single dose metyrapone test as an outpatient procedure to assess hypothalamic-pituitary-adrenal function.
J Clin Endocrinol Metab 2002; 87 5470-5475 IF 6.3
Award: Wissenschaftlicher Förderpreis Viollier 2003
18. Christ-Crain M., Meier C., Roth C.B., Huber P.R., Staub J.-J.; and Müller B. Basal TSH levels compared with TRH stimulated TSH levels for the diagnosis of different degrees of TSH suppression – diagnostic and therapeutic impact of assay performance.
Europ J Clin Invest 2002; 32: 931-37 IF 3.0
19. Christ-Crain M., Meier C., Guglielmetti M., Huber P.R., Riesen W.; Staub J.-J.; and Müller B.
Elevated Highly Sensitive C-reactive Protein and Homocysteine Levels: Cardiovascular Risk Factors in Subclinical and Overt Hypothyroidism? A Case-Control and a Randomized, Double- Blind, Placebo-Controlled Trial.
Atherosclerosis 2003; 166: 379-86 IF 3.8
20. Meier C., Trittibach P., Guglielmetti M., Staub J.-J., and Müller B. Serum thyroid stimulating hormone in assessment of tissue hypothyroidism in patients with overt primary thyroid failure:
cross-sectional survey.
BMJ 2003;326: 311-312 IF 14.1
Editorial: Toft A.D. and Beckett G.J. Thyroid function tests and hypothyroidism BMJ 2003;326 295-296
21. Morgenthaler N.G., Struck J., Chancerelle Y., Weglöhner W., Agay D., Bohuon C., Suarez- Domenech V., Bergmann A., Müller B. Production of Procalcitonin (PCT) in Non Thyroidal Tissue after LPS Injection.
Horm Metab Res 2003; 35: 290-5 IF 2.2
22. Linscheid P., Keller U., Blau N., Schär D., Müller B. Diminished Production of Nitric Oxide Synthase
Cofactor Tetrahydrobiopterin by Rosiglitazone in Adipocytes. Biochem Pharmacol 2003; 65: 593-
8 IF 4.7
23. Nylen E., Muller B., Becker K.L., Snider R. The future diagnostic role of procalcitonin levels: the need for improved sensitivity (letter). Clin Infect Dis 2003; 36: 823-4 IF 9.2 24. Meier C., Christ-Crain M., Guglielmetti M., Huber P.R., Staub J.-J.; Müller B. Prolactin
dysregulation in women with subclinical hypothyroidism: effect of levothyroxine replacement
therapy. Thyroid 2003; 13: 979-85 IF 4.8
25. Linscheid P., Seboek D., Nylen E.S., Langer I., Schlatter M., Keller U., Becker K.L., Müller B.: In Vitro and in Vivo Calcitonin I Gene Expression in Parenchymal Cells: A Novel Product of Human
Adipose Tissue. Endocrinology 2003; 144: 5578-5584 IF 5.0
Award: Servier Award of the Swiss Society of Endocrinology and Diabetes (SSED/SGED) 2004
26. Christ-Crain M., Meier C., Zulewski H., Huber P.R., Keller U.; Staub J.J. and Müller B. Effect of Restoration of Euthyroidism on Peripheral Blood Cells in Women with Subclinical Hypothyroidism.
Hormones (Horm Int J Endocrino) 2003; 2: 209-14 IF 2.4 27. Berneis K., Buitrago C., Müller B., Keller U., Tsakiris D.A. Antiphospholipid syndrome and
endocrine damage: why bilateral adrenal thrombosis?
Eur J Haematol 2003; 71: 299-302 IF 2.6
28. Meier C., Müller B., Christ-Crain M., Kunz M., Guglielmetti M., Staub J.J. and Kraenzlin M.
Restoration of Euthyroidism Accelerates Bone Turnover in Patients with Subclinical Hypothyroidism: Results from a Double-Blind Placebo-Controlled Study.
Osteoporosis Int 2004; 15: 209-16 [Epub Jan 16] IF 4.6 29. Christ-Crain M., Meier C., Puder J.J., Staub J.J., Huber P.R., Keller U.; and Müller B. Changes of
Liver Function Test correlate with the Improvement of Lipid Profile after Restoration of Euthyroidism in Patients with Subclinical Hypothyroidism. EXCLI Journal 2004; 3: 1-9
http://www.giftinfo.unimainz.de/EXCLI/volumes/Vol3/original_articles_vol3.htm IF 1.9 30. Christ-Crain M., Jaccard-Stolz D., Bingisser R., Gencay M., Huber P.R., Tamm M. and Müller B.
Effect of Procalcitonin-Guided Therapy on Antibiotic Use and Outcome in Lower Respiratory Tract Infections: cluster-randomized, single-blinded trial.
THE LANCET 2004; 363: 600-607, Epub Feb 10, 2004 (“Fast track” publication) IF 44.0 Talking points: Antibiotics: a breath of fresh air? The Lancet 2004; 363: 579
Journal Club: Al-Nakeeb S., Clermont G., Procalcitonin testing has the potential to reduce the unnesseary antibiotic use in patients with lower respiratory tract infections. Crit Care 2005: E5 (http://ccforum.com/articles/browse.asp?sort=Journal%20club%20critique&date=2-2005 Correspondence: Christ-Crain M., Jaccard-Stolz D., Tamm M. and Müller B. Procalcitonin- guided
antibiotic therapy in heart failure. The Lancet 2004; 363: 1555-6
Awards: - SGIM 2004 Lausanne: Highlight & Poster Award (1st Prize, cf Abstract #97) - Stiftung Pfizer Forschungs-Preis 2005
- Wissenschaftlicher Förderpreis Viollier 2005
31. Christ-Crain M., Meier C., Huber P., Zimmerli L., Trummler M., and Müller B. Comparison of Different Methods for the Measurement of Serum Testosterone in the Ageing Male.
Swiss Med Wkly 2004; 134: 193-7 IF 1.9
32. Mueller C., Huber R., Laifer G., Mueller B, Buerkle G, Perruchoud A.P. Procalcitonin and the early diagnosis of infective endocarditis. Circulation 2004; 109: 1707-10, Epub 2004 Apr 05 IF 14.7 33. Walter M.A., Christ-Crain M., Eckard B., Schindler C., Nitzsche E. U., Müller-Brand J. Müller B.
Radioiodine therapy in hyperthyroidism: Inverse correlation of pretherapeutic iodine uptake level and posttherapeutic outcome. Eur J Clin Invest 2004; 34: 365-70 IF 3.0 34. Christ-Crain M., Meier C., Huber P.R., Keller U.; Staub J.J. and Müller B. Effect of L-Thyroxine
Replacement Therapy on Skeletal and Cardiac Function in Subclinical Hypothyroidism.
The Endocrinologist 2004; 14: 161-6 IF 0.1
35. Christ-Crain M:, Müller B., Gasser T.C., Kränzlin M., Trummler M, Huber P.R., Meier C. Is there a Clinical Relevance of Biochemical Hypoandrogenism in Elderly Men?
J Urology 2004; 172: 624-7 IF 3.8
36. Linscheid P., Seboek D., Schaer D.J., Zulewski H., Keller U., Müller B.: Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-
activated adipocytes. Crit Care Med 2004: 32: 1715-21 IF 6.3
Editorial: Russwurm S., Reinhart K. Procalcitonin mode of action – New pieces in a complex puzzle Crit Care Med 2004: 32: 1801-2
37. Seboek D., Linscheid P., Zulewski H., Langer I., Christ-Crain M., Keller U., Müller B. Somatostatin is expressed and secreted by human adipose tissue upon infection and inflammation.
J Clin Endocrinol Metab 2004; 89: 4833-9 IF 6.3
Award: Annual Prize of the Swiss Diabetes Foundation 2004
38. von Mach M.-A., Hengstler J.G., Brulport M., Eberhard M., Schormann W., Hermes M., Prawitt D., Zabel B., Grosche J., Reichenbach A., Müller B., Weilemann L.S., Zulewski H. In vitro cultured islet-derived progenitor cells of human origin express human albumin in severe combined
imunodeficiency mouse liver in vivo (rapid communication).Stem cells 2004; 22: 1134-41 IF 7.8
39. Puder J.J., Atar M., Muller B., Pavan M., Keller U. Using insulin pen needles up to five times does not increase pain intensity nor affect needle tip shape. Diab Res Clin Pract 2005; 67: 119-23 IF 2.8
40. Morgenthaler N.G., Struck J., Christ-Crain M., Bergmann A., Müller B. Pro-Atrial Natriuretic Peptide (proANP) is a prognostic marker in sepsis similar to the APACHE II score.
Crit Care 2005; 9: R37-R45 (epub 14.12.04; http://ccforum.com/researcharticles) IF 6.4 Erratum: Crit Care. 2005 Apr;9(2):169. Epub 2005 Jan 31.
41. Walter M.A., Christ-Crain M., Müller B., Müller-Brand J. Radioiodine uptake and thyroid hormone levels on or off simultaneous carbimazole medication: A prospective paired comparison.
Nuklearmed – Nucl Med 2005; 44: 33-36 IF 1.3
42. Christ-Crain M., Meier C., Huber P.R., Zimmerli L., Müller B. Value of gonadotropin-releasing hormone testing in the differential diagnosis of androgen deficiency in elderly men.
J Clin Endocrinol Metab 2005; 90: 1280-6 IF 6.3
43. Linscheid P., Seboek D., Zulewski H., Keller U., Müller B.: Autocrine/paracrine role of
inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.
Endocrinology 2005; 146: 2699-708 [Epub Mar 10 2005] IF 4.6 44. Schütz P., Müller B., Christ-Crain M., Dick W., Haas H.G. Amino-bisphosphonates in heterotopic
ossification - A retrospective, interventional study of 5 consecutive cases.
Spinal cord 2005; 1-7 doi:10.1038/sj.sc.3101761 IF 1.8 45. Blum C.A., Muller B., Huber P., Kränzlin M., Schindler S., De Geyter C., Keller U., Puder J.J. Low-
grade Inflammation and Estimates of Insulin Resistance during the Menstrual Cycle in Lean and Overweight
Women. J Clin Endocrinol Metab 2005; 90: 3230-5 IF 6.3
Letter Reply: Puder J.J., Mueller B., Keller U. The biological variation of testosterone and sex hormone-binding globulin (SHBG) in polycystic ovary syndrome: implications for SHBG as surrogate marker for insulin resistance. J Clin Endocrinol Metab 2005; 90: 4419-20 46. Widmer I., Puder J., Koenig C. Pargger H., Zerkowski H.R., Müller B. Cortisol Response in
relation to the Severity of Stress and Illness: The “CORESSI”-Study J Clin Endocrinol Metab
2005; 90: 4579-86 IF 6.3
Editorial: Dickstein G: On the Term "Relative Adrenal Insufficiency"--or What Do We Really Measure with Adrenal Stimulation Tests?” J Clin Endocrinol Metab 2005;90 4973- 4974
47. Puder J.J., Lächelt S., Endrass J., Müller B., Keller U. What are disease perceptions and
treatment goals of insulin-treated diabetic patients? Swiss Med Wkly 2005; 135: 365-71 IF 1.9 48. Bocek T, Morgenthaler NG, Staub D., Nusbaumer C., Zellweger M.J., Wild D., Pfisterer M.E.,
Mueller-Brand J., Mueller B., Perruchoud A.P., Mueller C. Use of pro-atrial natriuretic peptide in the
detection of myocardial ischemia. Eur J Clin Invest 2005: 35: 450-56 IF 3.0 49. Viardot A., Huber P.R., Puder J., Zulewski H., Keller U., Müller B. Reproducibility of nighttime
salivary cortisol and its use in the diagnosis of hypercortisolism compared with urinary free cortisol and overnight dexamethasone suppression test. J Clin Endocrinol Metab 2005; 90:5730-6 IF 6.3 Comment: Trends & Insight. Endocrine Reviews 2005; Oct: 5
50. Meier C., Christ-Crain M., Christoffel-Courtin C., Staub J.J., Müller B. Serum estradiol after single dose hCG administration correlates with Leydig cell reserve in hypogonadal men: Reassessment
of the hCG stimulation test. Clin Lab 2005; 51: 509-15 IF 0.9
51. Puder J.J., Vargas S., Kraenzlin M., De Geyter C., Keller U., Müller B. Central fat excess in Polycystic Ovary Syndrome: Relation to low-grade inflammation and insulin resistance.
J Clin Endocrinol Metab 2005;90: 6014-21 IF 6.3
Award: Servier Award of the Swiss Society of Endocrinology and Diabetes (SSED/SGED) 2006 52. Briel M., Christ-Crain M., Schütz P, Young J, Huber P, Périat P, Bucher H.C., Müller B.
Procalcitonin-guided antibiotic use in acute respiratory tract infections in primary care – study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671] BMC Family Practice 2005; 6:34: 1-8
53. Christ-Crain M, Morgenthaler N.G., Müller C., Meier C., Nussbaumer C., Bergmann A., Staub J.J.
and Müller B. Pro-A-Type and N-Terminal Pro-B-Type Natriuretic Peptides in Different Thyroid
Function States.
Swiss Med Wkly 2005;135: 549-54 IF 1.9
54. Christ-Crain M., Morgenthaler N.G., Struck J., Bergmann A., Harbarth S., Müller B. Mid-regional Pro-Adrenomedullin (MR-proADM) as a prognostic marker in sepsis - an observational study.
Crit Care 2005; 9: R816-24 (epub; http://ccforum.com/researcharticles) IF 6.4 55. Puder J.J., Blum CA., Mueller B., De Geyter Ch., Dye L., Keller U. Menstrual cycle symptoms are
associated with low grade inflammation. Eur J Clin Invest 2006; 36: 58-64 IF 3.0 56. Linscheid P., Seboek D., Zulewski H., Scherberich A., Blau N., Keller U., and Müller B. Cytokine-
induced metabolic effects in human adipocytes are independent of endogenous nitric oxide.
Am J Physiol - Endoc M 2006; 290:E1068-77. Epub 2005 Dec 27 IF 4.8 57. Heizmann O., Haecker F.-M., Zumsteg U., Müller B., Oberholzer M., Oertli D. Presymtomatic
Thyroidectomy in Multiple Endocrine Neoplasia 2a. Eur J Surg Oncol 2006; 32: 98-102 IF 1.9 58. Walter MA, Seboek D, Demougin P, Bubendorf L, Oberholzer M, Müller-Brand J., Müller B.
Extraction of high-integrity RNA suitable for microarray gene expression analysis from long-term stored human thyroid tissues. Pathology 2006; 38: 249-53 IF 2.4 59. Timper K., Seboek D., Eberhardt M., Linscheid P., Christ-Crain M., Keller U., Müller B., Zulewski
H. Human adipose tissue derived mesenchymal stem cells differentiate into insulin, somatostatin and glucagon expressing cells. Biochem Biophys Res Comm 2006: 341: 1135-40 IF 2.5 60. Moriconi N., Kraenzlin M., Müller B., Keller U., Nusbaumer C. P. G., Stöhr S., Tamm M., Puder
J.J. Body composition and adiponectin serum concentrations in adult patients with cystic fibrosis.
J Clin Endocrinol Metab 2006; 91: 1586-90 IF 6.3
61. Walter M.A., Christ-Crain M., Schindler C., Müller-Brand J., Müller B. Outcome of Radioiodine Therapy Without, On or 3 Days Off Carbimazole: A Prospective Interventional 3-Group Comparison
Eur J Nucl Med Mol I 2006; 33: 730-7 IF 5.0
62. Christ-Crain M., Stolz D., Bingisser R., Müller C., Miedinger D., Huber P.R., Zimmerli W., Harbarth S., Tamm M. and Müller B. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial Am J Resp Crit Care Med 2006; 174: 84-93 IF 11.1 Editorial: Wunderink R.G. A CAP on Antibiotic Duration.
Am J Resp Crit Care Med 2006; 174: 3-5
Award: Prize of the Swiss Society of Internal Medicine (SGIM) 2007
63. Stolz D., Christ-Crain M., Gencay M., Bingisser R., Huber P.R., Müller B. and Tamm M.
Diagnostic Value of Clinical and Laboratory Parameters in Lower Respiratory Tract Infection.
Swiss Med Wkly 2006; 136: 434-40 IF 1.9
64. Eberhardt M, Salmon P, von Mach M.-A., HengstlerJG, Brulport M, Linscheid P, Seboek D, Oberholzer J., Barbero A., Martin I., Müller B., Trono D., Zulewski H. Multipotential nestin and Isl- 1 positive mesenchymal stem cells isolated from human pancreatic islets.
Biochem Biophys Res Comm 2006; 345: 1167-76 IF 2.5
65. Christ-Crain M., Morgenthaler N.G., Stolz D., Müller C., Bingisser R., Harbarth S., Tamm M., Struck J., Bergmann A. and Muller B. Pro-Adrenomedullin to Predict Severity and Outcome in Community-
Acquired Pneumonia [ISRCTN04176397] Crit Care 2006; 10: 3/R96 IF 4.6 Letter: Eisenhut M. A role for adrenomedullin in the pathogenesis of alveolar edema.
Critical Care, 2006 10:418
66. Christ-Crain M., Stoeckli R., Ernst A., Morgenthaler N.G., Bilz S., Korbonits M., Bergmann A., Müller B. and Keller U. Effect of Gastric Bypass and Gastric Banding on Proneurotensin Levels in Morbidly Obese Patients. J Clin Endocrinol Metab 2006; 91: 3544 - 7 IF 6.3 67. Puder J.J., Varga S., Nusbaumer C., Zulewski H., Bilz S, Müller B., Keller U. Women with
polycystic
ovary syndrome are sensitive to the TNF-alpha-lowering effect of glucose-induced hyperinsulinaemia.
Eur J Clin Invest 2006; 36: 883-9 IF 3.0
68. Müller B., Süess E., Schuetz P., Müller C., MD, Bingisser R., Morgenthaler N.G., Stolz D., Tamm M., Bergmann A., Christ-Crain M. Circulating levels of Pro-Atrial Natriuretic Peptide in Lower Respiratory
Tract Infections. J Intern Med 2006; 260: 568-76 IF 5.5
69. Stolz D., Christ-Crain M., Bingisser R., Gencay M., Huber P.R., Müller C., Leuppi J., Müller B and Tamm M. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 2007; 131: 9-19 IF 5.3 Editorial: Martinez F.J., Curtis J.L. Procalcitonin-Guided Antibiotic Therapy in COPD
Exacerbations: Closer But Not Quite There. Chest 2007; 131: 1-2
Award: Forschungspreis der Schweizerischen Gesellschaft für Pneumologie (GlaxoSmithKline) 2006
70. Walter M.A., Briel M., Christ-Crain M., Bonnema S.J., Cooper D.S., Bucher H.C., Müller-Brand J., Müller B. Effects of thyrostatic drug on radioiodine therapy: systematic review and meta-analysis of randomised controlled trials. BMJ 2007; 334:514-20 doi:10.1136/bmj.39114.670150.BE. IF 14.1 Editorial: Toft A., Sandeep T.C. Radioiodine treatment of hyperthyroidism. BMJ 2007; 384: 483-4 71. Müller B., Harbarth S., Stolz D., Bingisser R., Leuppi J., Müller C., Nusbaumer C., Tamm M. and.
Christ-Crain M. Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-
acquired pneumonia. BMC Inf Dis 2007; 7:10 doi:10.1186/1471-2334-7-10
http://www.biomedcentral.com/1471-2334/7/10 IF 3.1
72. Schütz P., Müller B., Trampuz A. Serum procalcitonin for discrimination of blood contamination from bloodstream infection due to coagulase-negative staphylococci – an observational pilot study
Infection 2007; DOI 10.1007/s15010-007-7065-0 IF 2.7
73. Müller B., Gencay M., Gibot S., Stolz D., Hunziker L., Tamm M., Christ-Crain M. Circulating Levels of Soluble triggering receptor expressed on myeloid cells (TREM-1) measurement in community-
acquired pneumonia. Crit Care Med 2007; 35: 990-1 IF 6.3
74. Müller B., Morgenthaler N.G., Stolz D., Schuetz P., Müller C., Bingisser R., Bergmann A., Tamm M. and Christ-Crain M. Circulating levels of copeptin, a novel biomarker, in lower respiratory tract
infections. Eur J Clin Invest 2007; 37: 145-52 IF 3.0
75. Morgenthaler N.G.*, Müller, B.*, Struck J., Bergmann A., Redl H., Christ-Crain M. Copeptin, a stable peptide of the arginine vasopressin (AVP) precursor, is elevated in hemorrhagic and septic shock.
Shock 2007; 28: 219-26 IF 2.9
76. Stolz D., Christ-Crain M., Morgenthaler N.G., Leuppi J., Miedinger D., Bingisser R., Müller C., Struck. J., Müller B. and Tamm M. Copeptin, C-reactive protein and Procalcitonin as Prognostic Biomarkers in Acute Exacerbation of COPD. Chest 2007; 131:1058-67 IF 5.3 77. Christ-Crain M., Jutla S., Widmer I., Couppis O., König C., Puder J., Edwards R., Müller B.,
Grossman A. Measurement of serum free cortisol shows discordant responsivity to stress and dynamic evaluation.
J Clin Endocrinol Metab 2007; 92:1729-35 IF 6.3
78. Conen D., Melly L., Kaufmann C., Bilz S., Amman P., Schär B., Sticherling C., Müller B., Osswald S. Amiodarone-induced thyrotoxicosis: long-term follow-up and independent predictors of
outcome. A retrospective cohort study. J Am Coll Cardiol 2007; 49: 2350-5 IF 14.2 Award: Mary & Ewald Betschmann Award for best thesis University Basel,2007
79. Lüthold S, Berneis K., Bady P., Müller B. Effects of infectious disease on plasma lipids and their diagnostic significance in critical illness. Eur J Clin Invest 2007; 37: 537-9 IF 3.0 80. Katan M, Morgenthaler N.G., Rutishauser J., Müller B. and Christ-Crain M. Anterior and posterior
pituitary function testing with simultaneous insulin tolerance test and a novel copeptin assay.
J Clin Endocrinol Metab 2007; 92: 2640-3 IF 6.3
81. Stolz D., Stulz A., Mueller B., Gratwohl A., Tamm M. BAL neutrophils, serum procalcitonin, and C-reactive protein to predict bacterial infection in the immunocompromised host..
Chest 2007; 132: 504–514 IF 5.3
82. Schuetz P., Christ-Crain M., Wolbers M., Schild U., Thomann R., Falconnier C., Widmer I., Neidert S., Blum C.A., Schoenenberger R., Henzen C., Bregenzer T., Hoess C., Krause M., Bucher H.C., Zimmerli W. and Mueller B. Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial.
BMC Health Services Research 2007; 7:102 doi:10.1186/1472-6963-7-102
http://www.biomedcentral.com/1472-6963/7/102 IF 1.8
83. Szinnai G, Morgenthaler N.G., Berneis K., Struck J., Müller B., Keller U., Christ-Crain M. Changes in plasma copeptin, the C-terminal portion of arginine vasopressin, during water deprivation and excess in healthy subjects. J Clin Endocrinol Metab 2007; 92: 3973–3978 IF 6.3 84. Walter M.A., Turtschi C.P., Schindler C., Minnig P., Müller-Brand J., Müller B. The Dental Safety
Profile of High-Dose Radioiodine Therapy for Thyroid Cancer: Long-Term Results of a Longitudinal Cohort Study.
J Nuclear Med 2007; 48:1620–1625 IF 6.4
85. Christ-Crain M., Stolz D., Jutla S., Couppis O., Müller C., Bingisser R., Schütz P., Tamm M., Edwards R. Müller B.and Grossman A. Free and total serum cortisol levels as predictors of severity
and outcome in community-acquired pneumonia.
Am J Resp Crit Care Med 2007; 176: 913–920 IF 11.1
86. Iten F., Müller B., Schindler C., Rochlitz C., Oertli D., Mäcke H.R., Müller-Brand J. and Walter M.A. Response to [90Yttrium-DOTA]-TOC Treatment is associated with Long-Term Survival Benefit in Metastasized Medullary Thyroid Cancer: A Phase II Clinical Trial. Clin Cancer Res
2007; 13: 6696 - 702 IF 7.8
Award: BRAHMS-Forschungspreis für Schilddrüsenerkrankungen 2008
87. Hügle T, Schuetz P, Mueller B., Laifer G., Tyndall A., Regenass S. and Daikeler T. Serum procalcitonin for discrimination between septic and non-septic arthritis.
Clin Exp Rheumatol 2008; 26: 305-8 IF 2.2
88. Hoch M., Eberle A, Seboek D., Peterli R., Peters T., Keller U., Müller B., Linscheid P. LPS induces
interleukin-6 and interleukin-8 but not tumor necrosis factor- in human adipocytes.
Cytokine 2008; 41: 29 - 37 IF 3.0
89. Schuetz P, Christ-Crain M., Morgenthaler N.G., Struck J., Bergmann, A., Müller B. Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis.
Endothelium 2007; 14:345–351 IF 2.4
90. Christ-Crain M., Kola B., Lolli F., Fekete C., Seboek D., Wittman G., Feltrin D., Igreja S., Ajodha S.,
Harvey-White J., Kunos G., Müller B., Pralong F., Aubert G., Arnaldi G., Giacchetti G., Boscaro M.,
Grossman A.B. and Korbonits M. AMP-Activated Protein Kinase Mediates Glucocorticoid-Induced Metabolic Changes: A Novel Mechanism in Cushing’s Syndrome.
FASEB J 2008; 22: doi: 10.1096/fj.07-094144 IF 7.0
91. Christ-Crain M; Breidthardt T, Stolz, D., Bingisser R., Tamm M., Mueller B., Mueller C. Use of B- type Natriuretic Peptide in the Risk Stratification of Community-acquired Pneumonia.
J Intern Med 2008; doi: 10.1111 ⁄ j.1365-2796.2008.01934.x IF 5.5 92. Schuetz P., Christ-Crain M, Schild U, Süess E., Facompre M., Baty L, Brutsche M., Müller B.
Effect of a 14-day treatment of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.
BMC Pulmonary Medicine 2008, 8:1 doi:10.1186/1471-2466-8-1 IF 1.6 93. Stolz, D., Breidthardt T, Christ-Crain M; Bingisser R., Miedinger D., Leuppi J., Mueller B., Tamm
M., Mueller C. Use of B-type Natriuretic Peptide in the Risk Stratification of Acute Exacerbations of Chronic Obstructive Lung Disease. Chest 2008; 133:1088-94 IF 5.3 94. Schuetz P., Stolz D., Mueller B., Morgenthaler N., Struck J., Mueller C., Bingisser R., Tamm M.
and
Christ-Crain M. Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia. BMC Inf Diseases 2008; 8:22. IF 3.1 95. Schuetz P., Koller M., Christ-Crain M., Steyerberg E., Stolz D., Müller C., Bucher H.C., Bingisser
R.
Tamm M., and Müller B. Predicting mortality with pneumonia severity scores: importance of model recalibration to local settings. Epidemiol Infect 2008; doi:10.1017/S0950268808000435 IF 2.8 96. Linscheid P., Christ-Crain M., Stoeckli R., Reusch B., Lutz T., Müller B., Keller U. Increase in High
Molecular Weight Adiponectin by Bariatric Surgery-induced Weight Loss.
Diabetes Obes Metab 2008; 10: 1266–1270 IF 4.3
97. Katan M., Morgenthaler N., Widmer I., Puder J., König C., Müller B., and Christ-Crain M. Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level:
Neuroendocrinol Lett 2008; 29(3):341-6 IF 1.3
98. Stolz D., Christ-Crain M., Morgenthaler N.G., Miedinger D., Leuppi J., Bingisser R., Müller C., Struck J., Müller B., Tamm M. Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD. Chest 2008; 134: 263-72 IF 5.3 99. Briel M., Schütz P, Müller B.*, Young J, Nusbaumer C., Périat P, Bucher H.C., Christ-Crain M..
Procalcitonin-guided antibiotic use in acute respiratory tract infections in primary care (*corresponding author)
Arch Int Med – JAMA Internal Medicine 2008;168: 2000-7 IF 11.5 Invited Commentary: Schwartz D.N. Arch Int Med – JAMA Internal Medicine 2008; 168: 2007- 8
100. Haeuptle J., Zaborsky R., Fiumefreddo R., Trampuz A., Steffen I, Frei R., Christ-Crain M., Müller B*. and Schuetz P. Prognostic Value of Procalcitonin in Legionella Pneumonia. (*corresponding author)
Clin Microbiol Infect 2009; 28: 55-60 DOI 10.1007/s10096-008-0592-5
(http://dx.doi.org/10.1007/s10096-008-0592-5) IF 2.9
101. Walter M.A., Schindler C., Christ-Crain M., Müller-Brand J., Müller B. Different strategies to overcome the effect of carbimazole on high- and low-dose radioiodine therapy: results from continuous dose-effect models. Europ J Clin Invest 2009; 39: 51-7 IF 3.0 102. Schuetz P., Briel M., Christ-Crain M.,Wolbers M., Stolz D., Tamm M., Bucher H., Müller B.
Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections. Protocol. The Cochrane Library 2008, Issue 4. Art.No.:CD007498. DOI: 10.1002/14651858.CD007498
www.thecochranelibrary.com IF 6.3
103. De Geyter C., Steinmann S., Müller B., Kränzlin M., Meier C. Pattern of Thyroid Function During Early Pregnancy in Women Diagnosed with Subclinical Hypothyroidism and Treated with L-
Thyroxine is Similar to That in Euthyroid Controls. Thyroid 2009; 19: 53-9 IF 4.8 104. Iten F., Müller B., Schindler C., Rasch H., Rochlitz C., Oertli D., Mäcke H.R., Müller-Brand J. and
Walter M.A. [90Yttrium-DOTA]-TOC response is associated with Survival Benefit in Iodine Refractory Thyroid Cancer: Long Term Results of a Phase 2 Clinical Trial.
Cancer 2009; 115:2052-62 IF 5.4
105. Schuetz P, Müller B., Nusbaumer C., Wieland M., Christ-Crain M. Circulating levels of growth hormone predict mortality and complement prognostic scores in critically ill medical patients.
Eur J Endocrinol 2009; 160: 157-163 IF 5.5
106. Gruber M., Christ-Crain M., Stolz D., Keller U., Müller C., Bingisser R., Tamm M., Müller B. and Schuetz P. Prognostic Impact of Plasma Lipids in Patients with Lower Respiratory Tract Infection – an Observational Study. Swiss Med Wkly 2009; 139: 166 – 172 IF 1.9 107. Fiumefreddo R., Haeuptle J., Zaborsky R., Christ-Crain M., Trampuz A., Steffen I, Frei R., Müller
B. and Schuetz P. Clinical Predictors for Legionella in Patients Presenting with Community- acquired Pneumonia to the Emergency Department.
BMC Pulm Med 2009, 9:4 doi:10.1186/1471-2466-9-4 IF 1.9 108. Walter M.A., Meier C., Radimerski T., Iten F., Kränzlin M., Müller-Brand J., de Groot J.W.B.,
Keam I.P., Links T. P., Müller B. Procalcitonin levels predict clinical course and progression free survival in medullary thyroid cancer Cancer 2010; 116: 31-40 IF 5.1 109. Keel C, Kränzlin M.E., Kränzlin C.A., Müller B. Meier C. Impact of Bisphosphonate Wash-out
Prior to Teriparatide Therapy in Clinical Practice. J Bone Miner Metab 2010;28(1):68-76 IF 2.3 110. Katan M., Fluri F., Morgenthaler N.G., Schütz P., Zweifel C., Bingisser R., Müller K., Meckel S.,
Gass A., Kappos L, Steck A., Engelter S., Müller B*. and Christ-Crain M*. Copeptin a novel, independent prognostic marker in patients with ischemic stroke. Ann Neurol 2009;66:799–808 IF 11.1
* equally contributing senior authors
111. Schuetz P., Christ-Crain M., Thomann R., Falconnier C., Wolbers M., Widmer I., Neidert S., Fricker T., Blum C., Schild U., Regez K., Schoenenberger R., Henzen C., Bregenzer T., Hoess C., Krause M.,
Bucher H.C., Zimmerli W. and Mueller B., for the ProHOSP Study Group. Effect of Procalcitonin- based Guidelines Compared to Standard Guidelines on Antibiotic Use in Lower Respiratory Tract
Infections: The Randomized-Controlled ProHOSP Trial. JAMA 2009; 302: 1059 - 66 IF 47.7 Editorial: Yealy D.M., Fine M.J. Measurement of Serum Procalcitonin. A step closer to tailored care for Respiratory Infections. JAMA 2009; 302: 1115-6
@Letter: Schuetz P., Zimmerli W., Mueller B. Procalcitonin-Based Guidelines and Lower Respiratory Tract Infections – Reply. JAMA. 2010;303:419-420 doi:10.1001/jama.2010.54 112. Schuetz P., Christ-Crain M., Albrich W., Zimmerli W., Mueller B. for the ProHOSP study group.
Guidance of antibiotic therapy with procalcitonin in lower respiratory tract infections: insights into the ProHOSP study. Virulence 2010;1:88-92. doi: 10.4161/viru.1.2.10488 IF 2.8 113. Heizmann O., Viehl C.T., Schmid R., Müller-Brand J., Müller B., Oertli D. Impact of concomitant
thyroid pathology on preoperative workup for primary hyperparathyroidism. Eur J Med Res 2009;
14: 37-41 IF 1.0
114. Stolz D., Smyrnios N., Eggimann P., Heard S.O., Pargger H.,Thakkar N.,Siegemund M., Marsch S., Rakic J. Mueller B., Tamm M. Procalcitonin for Reduced Antibiotic Exposure in Ventilator
Associated Pneumonia. Eur Respir J 2009; 34: 1364–1375 IF 7.1
115. Schuetz P., Christ-Crain M., Huber A.R., Mueller B. Long-term stability of procalcitonin in frozen samples and comparison of Kryptor® and VIDAS® automated immunoassays.
Clin Biochem 2010; 43: 341-4 IF 2.1
116. Hunziker S., Huegle T, Schuchardt D., Groeschl I., Schuetz P, Mueller B, Dick W., Eriksson U., Trampuz A. The value of procalcitonin for differentiation of infectious from non-infectious causes of fever after orthopedic surgery. Journal of Bone and Joint Surgery 2010;92:138-48 IF 3.3 117. Schuetz P., Batschwaroff M., Dusemund F., Albrich W., Bürgi U., Maurer M., Brutsche M., Huber
A., and Müller B. Effectiveness of a Procalcitonin Algorithm to Guide Antibiotic Therapy in respiratory tract infections outside of study conditions: a post-study survey.
Eur J Clin Microbiol Infect Dis 2010; DOI 10.1007/s10096-009-0851-0 IF 2.9 118. Fischer M., Dembinski K., Timper K., Radimerski T., Frey D.M., Zulewski H., Keller U., Müller B.,
Christ-Crain M., and Grisouard J. Metformin induces glucose uptake in both subcutaneous and visceral preadipocyte-derived adipocytes from both non-obese and obese patients. Research Letter
Diabetes Obes Metab 2010; 12: 356–359 IF 3.4
119. Grouzmann E, Drouard-Troalen L, Baudin E., Plouin PF, Müller B., Ruffieux C. Grand D., Buclin, T. Performance of Free and Sulphate-Conjugated Metanephrines measurement in Blood and Urine for the Diagnosis of Pheochromocytoma. Ann Emerg Medcrinol 2010; 162: 951–960 IF 5.4 120. Müller F., Christ-Crain M., Bregenzer T., Krause M., Zimmerli W., Müller B., and Schuetz P.for
the
ProHOSP Study Group. Procalcitonin levels Predict Bacteremia in Patients with community- acquired Pneumonia: A prospective cohort trial. CHEST 2010; 138:121-9 IF 6.5 corresponding author
121. Baehni C., Meier S., Spreiter P., Schild U., Regez K., Bossart R., Thomann R., Falconnier C., Christ-Crain M., De Geest S., Mueller B. and Schuetz P. Which patients with lower respiratory tract
infections need inpatient treatment? Perceptions of physicians, nurses, patients and relatives.
BMC Pulmonary Med 2010, 10:12 http://www.biomedcentral.com/1471-2466/10/12 IF 1.6 122. Katan M., Fluri F., Schütz P., Morgenthaler N.G., Zweifel C., Bingisser R., Kappos L, Steck A.,
Engelter S., Müller B*. and Christ-Crain M*. Midregional pro-atrial natriuretic peptide predicts outcome in patients with acute ischemic stroke. J Am Coll Cardiol 2010; 56: 1045-53 IF 14.2
*equally contributing senior author
123. Urwyler S.A., Schuetz P., Fluri F., Morgenthaler N.G., Zweifel C., Bergmann A., Bingisser R., Kappos L., Steck A., Engelter S., Müller B., Christ-Crain M. and Katan M. The prognostic value of Copeptin: 1-year outcome in patients with acute stroke. Stroke 2010; 41: 1564-7 IF 6.0 124. Schuetz P., Wolbers M., Christ-Crain M., Thomann R., Falconnier C., Widmer I., Neidert S.,
Fricker T., Blum C., Schild U., Morgenthaler N.G., Schoenenberger R., Henzen C., Bregenzer T., Hoess C.,
Krause M., Bucher H.C., Zimmerli W. and Mueller B., for the ProHOSP Study Group.
Prohormones for Prediction of Adverse Medical Outcome in Community-Acquired Pneumonia and Lower Respiratory Tract Infections. Crit Care 2010 14:R106 http://ccforum.com/content/14/3/R106
IF 6.4
125. Neidert S., Schuetz P., Mueller B., Christ-Crain M. Dexamethasone suppression test predicts later development of an impaired adrenal function after a 14-day course of prednisone in healthy
volunteers. Eur J Endocrinol 2010; 162: 943 – 49 IF 5.4
126. Katan M., Nigro N., Fluri F.,Schuetz P., Morgenthaler N.G., Jax F., Meckel S., Gass A., Bingisser R., Steck A., Kappos L., Engelter S., Müller B., and Christ-Crain M. Stress hormones predict cerebrovascular re-events in patients with acute transient ischemic attacks.
Neurology 2011; 76: 563-6 IF 8.3
127. Zweifel C., Katan M., Jost G., Schuetz P., Morgenthaler N.G., Siegemund M., Wasner M., Merlo A.,
Müller B., Christ-Crain M. Copeptin is associated with mortality and outcome in patients with acute intracerebral hemorrhage.
BMC Neurology 2010; 10:34 http://www.biomedcentral.com/1471-2377/10/34 IF 2.2 128. Radimerski T.M., Grisouard J., Timper K., Zulewski H., Christ-Crain M., Keller U, and Müller B.
Role of calcium in lipopolysaccharide-induced CALC gene expression in human adipocytes.
Innate Immunity 2011; 17: 403 Epub 2010; Aug 3 IF 4.0
129. Franchini M, Monnais E, Seboek D, Radimerski T, Zini E, Kaufmann K, Lutz T, Reusch C, Ackermann M, Muller B, Linscheid P. Insulin resistance and increased lipolysis in bone marrow derived adipocytes stimulated with agonists of Toll-like receptors.
Horm Metab Res 2010; 42: 703-9 IF 2.2
130. Schuetz P., Widmer I., Chaudri A., Christ-Crain M., Zimmerli W., and Mueller B. for the ProHOSP Study Group. Prognostic value of Procalcitonin in Community-Acquired Pneumonia.
Eur Resp J 2011; 37: 384–392 IF 12.2
131. Kuster G., Nietlispach F., Kiowski W., Schindler R., Bernheim A., Schuetz P., Müller B.,
Morgenthaler N.G., Rüter F., Riesen W., Rickli H., Brunner La-rocca H.P. Role of RAS inhibition in the regulation of Cu/Zn-SOD in the cardiac and peripheral arterial beds in humans.
Clin Pharmacol Ther 2010; 87: 686 - 92 IF 6.0
132. Gencay M.M.C., Stolz D., Christ-Crain M., Müller B., Roth M. and Tamm M. Single and multiple viral infections in lower respiratory tract infection. Respiration 2010; 80: 560-7 IF 2.3 Editorial: Hegele R.G. Viruses and Lower Respiratory Tract Infections: Does more mean worse?
Respiration 2010; DOI: 10.1159/000320329
133. Schütz P., Leuppi J., Tamm M., Briel M., Bingisser R., Duerring U., Müller B., Schindler C., Viatee S., Rutishauser J. Short versus conventional term glucocorticoid therapy in acute exacerbation of chronic obstructive pulmonary disease: the "REDUCE*" trial. Design and baseline characteristics.
Swiss Med Wkly 2010; 140:w13109 IF 1.9
134. Grisouard J., Timper K., Radimerski T., Frey D.M., Peterli R., Kola B., Korbonits M., Herrmann P., Krähenbühl S., Zulewski H., Keller U., Müller B., Christ-Crain M. Mechanisms of metformin action on glucose metabolism in human adipocytes. Biochem Pharm 2010; 80: 1736-45 IF 4.7 135. Spreiter P., Meier S., Baehni C., Schild U., Regez K., Bossart R., Thomann R., Falconnier C.,
Widmer I., Neidert S., Christ-Crain M., Mueller B. and Schuetz P. Steps to take to reduce length of hospital stay in patients with lower respiratory tract infections: A prospective cohort study.
Home Health Care Management & Practice 2011; 27: 184-91 corresponding author
doi: 10.1177/1084822310384857 IF 0.6
136. Grisouard J., Bouillet E., Timper K., Radimerski T., Dembinski K., Peterli R., Zulewski H., Keller U., Müller B., Christ-Crain M. Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharides (LPS)-induced lipolysis in human adipocytes.
Innate Immunity 2012; 18: 25 – 34 Epub 2010 Nov 18 IF 4.0 137. Guertler C., Wirz B., Christ-Crain M., Zimmerli, W., Müller B.*, Schuetz P. Inflammatory response
on admission predicts long term mortality risk in community-acquired pneumonia.
Eur Resp J 2011; 37: 1439–1446 IF 12.2
Editorial: Mortensen E.M. Potential causes of increased long-term mortality after pneumonia Eur Respir J 2011; 37: 1306–1307
* corresponding author
138. Timper K., Grisouard J., Radimerski T., Dembinski K., Peterli R., Frey D.M., Haering A., Zulewski H., Keller U., Müller B. and Christ-Crain M. Glucose-dependent insulinotropic polypeptide (GIP) induces calcitonin gene related peptide (CGRP) and procalcitonin (Pro-CT) production in human adipocytes.
J Clin Endocrinol Metab 2011; 96:E297-303. Epub 2010 Nov 24 IF 6.3
139. Vazquez M.*, Jockers*, Christ-Crain M, Zimmerli W., Müller B.§ and Schuetz P. for the ProHOSP Study Group. Pro-atrial natriuretic peptide (ProANP) predicts short and longterm outcomes in respiratory tract infections: A prospective validation study.
Int J Cardiol 2012; 156: 16-23; DOI 10.1016/j.ijcard.2010.10.037 IF 7.1
*equally contributing, §corresponding author
140. Bernasconi M., Tamm M., Bingisser R., Miedinge D., Leuppi J., Müller B., Christ-Crain M., Stolz D. Midregional pro-atrial natriuretic peptide predicts survival in exacerbations of COPD.
CHEST 2010; 140: 91-9 IF 5.3
141. Meyer S., Schuetz P., Wieland M., Nusbaumer C., Mueller B., Christ-Crain M., Low
Triiodothyronine Syndrome: a prognostic marker for outcome in sepsis ? Endocrine 2011; 39:
167-74 IF 1.4
142. Schulte J., Struck J., Köhrle J.., Müller B. Circulating levels of peroxiredoxin 4 as a novel biomarker of oxidative stress in patients with sepsis: an observational study. Shock 2011; 35:
460-5 IF 2.9
143. Grisouard J.; Timper K. Bouillet. E.; Radimerski T.M., Dembinski K., Frey D.M., Peterli R., Zulewski H.,Keller U., Müller B., Christ-Crain M. Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser 554 and -induced lipolysis in human adipocytes.
Arch Physiol Biochem 2011; 117: 209–214 DOI: 10.3109/13813455.2010.550925 IF 1.1 144. Neidert S., Katan M., Schuetz P., Fluri F., Ernst A., Bingisser R., Kappos L., Engelter S., Steck
A.,
Mueller, B., Christ-Crain M. Anterior pituitary-axis hormones and outcome in acute ischemic stroke.
J Int Med 2011; 269: 420-32 IF 6.8
145. Schuetz P., Christ-Crain M., Zimmerli W., Mueller B. for the ProHOSP study group. Repeated measurements of Endothelin-1 precursor peptides predict the outcome in community-acquired pneumonia.
Intens Care Med 2011; 37: 970-80 IF 5.4
146. Albrich W.C, Dusemund F., Rüegger K., Christ-Crain M., Zimmerli W., Bregenzer T., Irani S., Bürgi U., Reutlinger B., Müller B. and Schuetz P. Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections:
Derivation of a clinical algorithm
BMC Inf Diseases 2011; 11:112 IF 3.1
corresponding author
147. Breidthardt T., Christ-Crain M., Stolz D., Bingisser R., Drexler B., Klima T., Balmelli C., Schuetz P., Haaf P., Schärer M., Tamm M., Müller B., Mueller C. A Combined Cardiorenal Assessment using B-type Natriuretic Peptide and Plasma Neutrophil Gelatinase–Associated Lipocalin for the Prediction of Acute Kidney Injury in Lower Respiratory Tract Infections. Am J Med 2012; 125;
168-175 IF 5.4
148. Zweifel C, Katan M., Schuetz P., Ernst A., Mariani L., Müller B., Christ-Crain M. Growth hormone and outcome in patients with intracerebral haemorrhage – a pilot study.
Biomarkers 2011; 16: 511-6. doi: 10.3109/1354750X.2011.599074. Epub 2011 Aug 3 IF 2.2 149. Schuetz P, Albrich W.C., Suter I., Hug B.L., Christ-Crain M., Holler T., Henzen C., Krause M.,
Schoenenberger R., Zimmerli W., Mueller B. Quality of care delivered by fee-for-service and DRG hospitals in Switzerland in patients with community-acquired pneumonia.
Swiss Med Wkly 2011;141:w13228 IF 1.9
150. Albrich W.C., Rüegger K., Dusemund F., Bossart R., Regez K., Schild U., Conca A., Schuetz P., Sigrist T., Huber A., Reutlinger B., Müller B. Optimized Patient Transfer using an Innovative Multidisciplinary Assessment in the Kanton Aargau (OPTIMA I) - an observational survey in lower respiratory tract infections. Swiss Med Wkly 2011; 141:w13237 IF 1.9 151. Albrich W.C., Dusemund F., Bucher B., Meyer S., Thomann R., Kühn F., Bassetti S., Sprenger
M.,
Baechli E., Sigrist Th., Schwietert M., Amin D., Hausfater P., Carre E., Gaillat J., Schuetz P., Regez K., Bossart R., Schild U., Müller B. Effectiveness and safety of Procalcitonin-guided antibiotic therapy in lower respiratory tract infections in “real life”: an international, multicenter post-study survey (ProREAL).
Arch Int Med – JAMA Internal Medicine 2012; 172: 715-22 IF 11.5
Editorial: Gilbert D. Serum Procalcitonin levels. It is all about confidence.
Arch Int Med – JAMA Internal Medicine 2012; 172: 722-3
152. Grisouard J. Dembinski K., Mayer D., Keller U., Müller B., Christ-Crain M. Targeting AMP-
activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation. IF 1.5 Diabetology & Metabolic Syndrome 2011; 3:16 (http://www.dmsjournal.com/content/3/1/16) 153. Nigro N., Müller B., Morgenthaler N.G., Fluri F., Schütz P., Neidert S., Christ-Crain M., Katan M.
Copeptin,the stable peptide of the vasopressin precursor, for the differential diagnosis of sodium imbalance in
patients with acute diseases
Swiss Med Wkly 2011 Oct 11;141:w13270. doi: 10.4414/smw.2011.13270. IF 1.9 154. de Marchis G.M., Brekenfeld K., Buhl D., Mattle H., Arnold M., Müller B., Christ-Crain M., Katan
M. Copeptin and Risk Stratification in Patients with Ischemic Stroke and Transient Ischemic
Attack: the CoRisk Study. Int J Stroke 2013;8:214-8 IF 2.4
155. Schwappach D.L.B., Frank O., Koppenberg J., Müller B., Wasserfallen J.B. Patients’ and healthcare
workers’ perceptions of a patient safety advisory. IF 2.0
Int J Qual Health Care 2011; 1-8 DOI 10.1093/intqhc/mzr062
156. Nowak A., Breidthardt T., Christ-Crain M., Bingisser R., Meune C., Tanglay Y., Heinisch C., Reiter M., Meissner J., Drexler B., Arenja N., Stelzig C., Freese M., Twerenbold R., Stolz D., Tamm M., Müller B., and Müller C. Direct Comparison of Three Natriuretic Peptides for prediction of short- and long-term mortality in community acquired pneumonia.
CHEST 2012 Apr;141:974-82. Epub 2011 Dec 1 IF 5.3
157. Osthoff M.; Katan M.; Fluri F.; Schuetz P.; Bingisser R.; Kappos L.; Steck A.J.; Engelter S.T.;
Mueller B.; Christ-Crain M.; Trendelenburg M. Mannose-Binding Lectin Deficiency Is Associated With Smaller Infarction Size and Favorable Outcome in Ischemic Stroke Patients.
PLOS ONE 2011;6(6):e21338. Epub 2011 Jun 21 IF 4.1
158. Hunziker S., Semmer N.K., Tschan F., Schuetz P., Mueller B., Marsch S. Dynamics and
Association of Different Acute Stress Markers with Performance during a Simulated Rescscitation
Resuscitation. 2012; 83(5):572-8 IF 4.1
159. Berkmann S., Fandino J., Mueller B., Remonda L., Landolt H. Intraoperative MRI and endocrinological outcome of transsphendoidal surgery. Acta Neurochir 2012;154(4):639-47;
DOI 10.1007/s00701-012-1285-5 IF 1.5
160. Labarère J., Schuetz P., Renaud B., Claessens Y.-E., Albrich W., Mueller B. Validation of a Clinical
Prediction Model for Early Admission to the Intensive Care Unit of Patients with Pneumonia.
Acad Emerg Med 2012; 19(9):993-1003 IF 1.9
161.Schuetz P., Briel M., Christ-Crain M., Stolz D., Bouadma L., MD, Wolff M., Luyt C.E., Chastre J., Tubach F., Kristoffersen K.B., Wei L., Burkhardt O., Welte T., Schroeder S., Nobre V., Tamm M., Bhatnagar N., Bucher H.C., Mueller B. Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: a systematic review and meta-analysis of individual patient
data. Clin Infect Dis 2012; 11: Jul 3. [Epub ahead of print] IF 9.2 162. Renaud B., Schuetz P., Claessens Y.-E., Labarère J., Albrich W., Mueller B. for the ProHOSP
study
group. Proadrenomedullin improves Risk of Early Admission to ICU score for predicting early severe community-acquired pneumonia. CHEST 2012; 142(6):1447-54 IF 5.3 163. Suter-Widmer I.E., Christ-Crain M., Zimmerli W., Albrich W., Mueller B.*, Schuetz P. Predictors
for length of hospital stay in patients with community-acquired Pneumonia: Results from a Multicenter study.
BMC Pulmonary Med 2012; 12: 21 http://www.biomedcentral.com/1471-2466/12/21 IF 1.6
* corresponding author
164. Koenig K., Potlukova E., Mueller B., Christ-Crain M., Trendelenburg M. MBL serum levels in patients with sepsis correlate with thyroid function but not with outcome. Clin Immunol 2012;
144(1):80-2 IF 4.1
165. Conca A., Bossart R., Regez K., Schild U., Wallimann G., Schweingruber R., Hantikainen V., Tobias P., Albrich W., Rüegger K., Dusemund F., Bürgi U., Sigrist T., Mariacher-Gehler S., Huber A., Schütz P., Müller B., Reutlinger B. OPTIMA – Optimierter Patienten-Transfer durch innovatives multidisziplinäres Assessment: Projektbeschreibung der Phase I. Zeitschrift für
Pflegewissenschaft 2012; 5: 291-8 DOI: 10.3936/1155
Open access in English: Optimized patient transfer through innovative multidisciplinary assessment: Project description of phase I. [Translated from the original article in German
published in Pflegewissenschaft 2012; 5:291-8] Medical Science-15-1297R1 IF 1.6 166. Scherr A., Graf R., Christ-Crain M., Bain M., Müller B., Lajaunias F., Tamm M., Stolz D.
Pancreatic stone protein (PSP/reg) is a predictor of positive sputum bacteriology in acute exacerbations of COPD.
CHEST 2013; 143(2):379–387 IF 5.3
167. Dusemund F.*, Bucher B.*, Meyer S.*, Thomann R., Kühn F., Bassetti S., Sprenger M., Baechli E., Sigrist Th., Schwietert M., Amin D., Hausfater P., Carre E., Schuetz P., Gaillat J., Regez K., Bossart R., Schild U., Mueller B., Albrich W.C. Influence of procalcitonin on decision to start antibiotic treatment in patients with a lower respiratory tract infection – insight from the observational multicentric ProREAL surveillance.
Eur J Clin Microbiol 2013;32(1):51-60 DOI 10.1007/s10096-012-1713-8 IF 2.9 168. Schuetz P., Müller B. , Christ-Crain M., Stolz, D., Tamm M., Bouadma L., Luyt C.E., Wolff M.,
Chastre J., Tubach F., Kristoffersen K.B., Burkhardt O., Welte T., Schroeder S., Nobre V., Wei L., Bhatnagar N., Bucher H.C., Briel M. Procalcitonin to initiate or withhold antibiotic therapy in acute respiratory tract infections – an individual patient data (IPD) analysis.
Cochrane DB Syst Rev 2012; 9: 1 - 71 IF 5.9
- Discussed in: Ann Int Med 2013; 158:JC5 Therapeutics
169. Berkmann S., Fandino J., Müller B., Kothbauer K.F., Henzen C., Landolt H. Pituitary Surgery:
Experience from a large Network in Central Switzerland. Swiss Med Wkly 2012;142:w13680 IF 1.9
170. Hartmann O., Schuetz P., Albrich W., Anker S.D., Müller B., and Schmidt T. The added value of serial biomarker measurements for survival prediction: Finding the right answers in time-
dependent Cox regression.
Int J Cardiol 2012;161:166-73. doi: 10.1016/j.ijcard.2012.09.014. Epub 2012 Sep 24 IF 7.1 171. Fluri F., Schindler C., Morgenthaler N.G., Mueller B., Christ-Crain M., Katan M. Copeptin,
Procalcitonin and routine inflammatory markers - predictors of infection after stroke.
PLOS one 2012; 7: e48309 IF 4.1
172. Timper K., Grisouard J., Sauter Zlinszky N., Radimerski T., Dembinski K., Peterli R., Häring A., Beglinger C., Frey D.M., Zulewski H., Keller U., Müller B. and Christ-Crain M. Glucose-dependent insulinotropic polypeptide (GIP) induces cytokine expression, lipolysis and insulin resistance in human adipocytes. Am J Physiol – Endoc M 2013; 304(1):E1-13 IF 4.8 173. Dusemund F., Steiner M., Vuillomenet A., Müller Chr., Bossart R., Regez K., Schild U., Conca A.,
Huber A., Reutlinger B., Mueller B., Albrich W.C. Multidisciplinary Assessment to Personalize Length of Stay in Acute Decompensated Heart Failure (OPTIMA II ADHF). J Clin Med Res 2012;
4: 402-9
174. De Marchis GM., Katan M., Weck A., Fluri F., Foerch C., Findling O., Schuetz P., Buhl D., El- Koussy M., Gensicke H., Seiler M., Morgenthaler N.G., Mattle H., Müller B., Christ-Crain M., Arnold M. Copeptin Adds Prognostic Information After Ischemic Stroke: Results From the CoRisk
Study. Neurology 2013; 80: 1-9 IF 8.3
175. Arici B., Maeder M., Schuetz P., Mueller B., Albrich W.C. Potential role of biomarkers in the management of syncope. International Journal of Clinical Medicine (IJCM) 2012; 3: 744-50 176. Albrich W.C., Müller B. für das ProREAL study team. Wirksamkeit und Sicherheit der
Procalcitonin-gesteuerten Antibiotikatherapie bei Infekten der unteren Atemwege: Einsichten in die internationale, multizentrische Poststudy-Surveillance (ProREAL). Der Mikrobiologe 2012; 22:
83-8
177. Albrich W.C., Rüegger K., Dusemund F., Schuetz P., Arici B., Litke A., Blum C., Bossart R., Regez K., Schild U., Guglielmetti M., Conca A., Schäfer P., Schubert M., de Geest S., Reutlinger B., Irani S., Bürgi U., Huber A., Mueller B. Biomarker-enhanced triage in respiratory infections – a proof-of-concept feasibility trial. Eur Respir J 2013; 42: 1064-75 DOI:
10.1183/09031936.00113612 IF 7.1
