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Secondary Metabolites from a Streptomyces Strain Isolated from Livingston Island, Antarctica

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Secondary Metabolites from a Streptomyces Strain Isolated from Livingston Island, Antarctica

Veneta Ivanova

a,

*, Monica Oriol

b

, Maria-Jesus Montes

b

, Angela Garcı´a

b

and Jesus Guinea

b

a Institute of Microbiology, Bulgarian Academy of Sciences, “Acad. G.Bonchev-Str.”, Bl.26, 1113 Sofia, Bulgaria

b University of Barcelona, Faculty of Pharmacy, Department of Microbiology, c/Juan XXIII s/n, 08028 Barcelona, Spain

* Author for correspondence and reprint requests

Z. Naturforsch.56 c,1Ð5 (2001); received September 6/November 6, 2000 Streptomycessp. 1010, Secondary Metabolites

The producing strainStreptomyces sp.1010 was isolated from a shallow sea sediment from the region of Livingston Island, Antarctica. From the culture broth of this strain naturally active secondary metabolites were isolated identical to phthalic acid diethyl ester (C12H14O4, MW. 222); 1, 3-bis (3-phenoxyphenoxy)benzene (C30H22O4, MW.446); hexanedioic acid dioc- tyl ester (C22H42O4, MW.370) and the new substance 2-amino- 9, 13 -dimethyl heptadecanoic acid (C19H39NO2, MW.313). These compounds represent diverse classes of chemical struc- tures and provide evidence for the untapped biosynthetic potential of marine bacteria from Antarctica.

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