Pulmonary Tuberculosis in Older Adults: Increased Mortality Related to Tuberculosis within Two months of Treatment Initiation
Authors: Isano Hase,1,2 Katelynne Gardner Toren,3 Hitomi Hirano,1 Kimiko Sakurai,4 David J Horne,3,5 Takefumi Saito,1 Masahiro Narita,3,5
Affiliations:
1. Department of Respiratory Medicine, National Hospital Organization Ibarakihigashi National Hospital, Ibaraki, Japan
2. Department of Pulmonary Medicine, Saitama City Hospital, Saitama, Japan
3. TB Control Program, Public Health - Seattle & King county, Seattle, WA
4. Department of Health Information Management, National Hospital Organization Ibarakihigashi National Hospital, Ibaraki, Japan
5. Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA
Corresponding Author:
Isano Hase, MD
Department of Respiratory Medicine, National Hospital Organization Ibarakihigashi National Hospital
825, Terunuma. Tokai-mura, Naka-gun, Ibaraki 319-1113, Japan
Email: isanotaki@gmail.com
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Supplementary materials
Table S1. Differences in time to death related to TB by age groups
Age group (years) N of individuals with
death
Mean Standard Deviation
Median Q1 Q3 IQR
18-44 1 82.0 - 82.0 82.0 82.0 0
45 -64 1 10.0 - 10.0 10.0 10.0 0
65- 74 5 33.2 22.2 32.0 18.0 46.0 28.0
75-83 12 67.7 62.8 48.5 17.5 104.0 86.5
84+ 26 77.2 64.7 50.5 28.0 103.0 75.0
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Table S2. Differences in time to last adverse event by age groups
Age group (years) N of individuals with
adverse events
Mean Standard Deviation
Median Q1 Q3 IQR
18-44 4 29.5 27.1 17.0 14.5 44.5 30.0
45 -64 11 22.4 15.5 14.0 12.0 37.0 25.0
65- 74 10 32.4 23.9 29.0 20.0 39.0 19.0
75-83 17 24.0 24.8 10.0 9.0 37.0 28.0
84+ 15 46.0 31.6 45.0 21.0 62.0 41.0
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