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GC-MS of Crinum latifolium L. Alkaloids Nguyen Thi Ngoc Tram

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GC-MS of Crinum latifolium L. Alkaloids

Nguyen Thi Ngoc Tram

a

, Maya Mitova

b

, Vassya Bankova

b

, Nedyalka Handjieva

b

and Simeon S. Popov

b,

*

a Vietnam Pharmaceutical Corporation, Laboratory for Chemistry and Technology of Natural Substances, 24 Nguyen Thi Nghia Str., Dist.1, Ho Chi Min City, Vietnam

b Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. Fax: ++3 59-7 00-2 25. E-mail: simpopov@orgchm.bas.bg

* Author for correspondence and reprint request Crinum latifoliumL., Amaryllidaceae, Alkaloids

Z. Naturforsch.57 c,239Ð242 (2002); received October 2/November 29, 2001

A GC-MS analysis of underivatized alkaloids from leaves ofCrinum latifoliumwas per- formed. From the identified 15 alkaloids, 9 were found for the first time in this plant. Almost all alkaloids belonged to the crinane type. Substantial changes in the methylation and oxida- tion pattern of the alkaloids at and after flowering were observed.

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