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Fig.S1: NoxO1 and p47phox contribute to cardiovascular homeostasis.

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0.00 0.05 0.10 0.15 0.20 0.25 0.30

STZ - + - + - + - +

WT NO1-/- p47-/- O1/47-/-

Stroke volume Systolic pressure/ heart rate

*

stroke volume

0 2 4 6

STZ - + - + - + - +

WT NO1-/- p47-/- O1/p47-/-

Heart/ body weight

(mg/g)

Fig.S1: NoxO1 and p47phox contribute to cardiovascular homeostasis. A: stroke volume calculated by the ratio of systolic pressure by heart rate. B: heart to body weight ratio. n ≥8. *p<0.05 WT STZ vs. O1/47-/- STZ.

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