0.00 0.05 0.10 0.15 0.20 0.25 0.30
STZ - + - + - + - +
WT NO1-/- p47-/- O1/47-/-
Stroke volume Systolic pressure/ heart rate
*
stroke volume
0 2 4 6
STZ - + - + - + - +
WT NO1-/- p47-/- O1/p47-/-
Heart/ body weight
(mg/g)
Fig.S1: NoxO1 and p47phox contribute to cardiovascular homeostasis. A: stroke volume calculated by the ratio of systolic pressure by heart rate. B: heart to body weight ratio. n ≥8. *p<0.05 WT STZ vs. O1/47-/- STZ.