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Additional file 11. Hierarchical cluster analysis and heatmap showing expression of angiogenesis-associated genes (taken from PANTHER pathway) in UKF-NB-2, UKF-NB-2rVCR10, or UKF-NB-2rCDDP1000cells. Data were merged from two
independent experiments each comparing UKF-NB-2 cells with a chemoresistant sub-line. UKF-NB-2a was analysed together with UKF-NB-2rVCR10. UKF-NB-2b was analysed together with UKF-NB-2rCDDP1000.
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between the parental chemosensitive UKF-NB-3 neuroblastoma cell line and the vincristine-resistant sub-line UKF-NB-3 r VCR 10 as indicated by PANTHER pathway
between the parental chemosensitive UKF-NB-3 neuroblastoma cell line and the cisplatin-resistant sub-line UKF-NB-3 r CDDP 1000 as indicated by PANTHER pathway
between the parental chemosensitive UKF-NB-3 neuroblastoma cell line and the doxorubicin resistant sub-line UKF-NB-3 r DOX 20 as indicated by PANTHER pathway
(b) Levels of survivin and γ H2AX (indicating DNA damage) in UKF- NB-3 cells transduced with a lentiviral vector encoding for shRNA targeting p53 (UKF-NB-3 p53shRNA ) in response
Entwicklungsziele zur Verbesserung des derzeitigen Zustandes werden kartographisch nicht dargestellt; sie sind alle im Textteil (Kap. 5.1) formuliert. als
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