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Scoparone Inhibits Ultraviolet Radiation-Induced Lipid Peroxidation Paul Sourivong

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Scoparone Inhibits Ultraviolet Radiation-Induced Lipid Peroxidation

Paul Sourivong

a

, Kristina Schronerova´

b

, and Mela´nia Babincova´

b,

*

a Willis-Knighton Cancer Center, Department of Radiation Oncology, 2600 Kings Highway, Shreveport, Louisiana 71103, USA

b Department of Biophysics, Comenius University, Mlynska´ dolina F1, 842 48 Bratislava, Slovakia. Fax: +42 12 65 42 58 82. E-mail: babincova@fmph.uniba.sk

* Author for correspondence and reprint requests

Z. Naturforsch.62 c, 61Ð64 (2007); received August 8/September 7, 2006

Antioxidant capabilities of scoparone, the component ofArtemisia scopariaand other me- dicinal plants, against lipid peroxidation induced by ultraviolet radiation or Fenton reaction have been analyzed. Lipid peroxidation was monitored by measuring the absorption spectra of the conjugated dienes and quantified by the Klein oxidation index. Obtained results imply that scoparone is a very efficient inhibitor of ultraviolet radiation-induced lipid peroxidation and damage.

Key words: Artemisia scoparia, Ultraviolet Radiation, Lipid Peroxidation

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