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Mean change from baseline score (FACT-Taxane) Appendix Figure A1

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(1)

A) FACT-taxane TOI B) FACT-taxane total score

C) FACT-G total score D) Taxane sub-scale

Treatment by course (vs. SD 260mg) P-value MD 220mg by course 0.333 LD 180mg by course 0.011

Appendix Figure A1. Mean change from baseline score (FACT-Taxane)

Appendix Figure A1. Mean changes and 95% confidence interval from baseline for A) Functional Assessment of Cancer Therapy-Taxane trial outcome index (FACT-Taxane TOI), B) FACT-Taxane total, C) FACT-General total, and D) Taxane subscale scores.

(2)

A) CFS total B) Physical

C) Affective D) Cognitive

Appendix Figure A2. Mean change from baseline score (CFS)

Appendix Figure A2. Mean changes and 95%

confidence interval from baseline for A) Cancer

Fatigue Scale (CFS) total, B) Physical, C) Affective, and D) Cognitive subscale scores.

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