Arroyave, MD, Blair Ford, MD, Megan P. Feeney, MPH, Kimberly T. Kwei, MD PhD, Linn E. Katus, DO MSc, Sheng-Han Kuo, MD,Hiral Shah, MD, Cheryl Waters, MD, Linda M. Winfield, RN MPH, James C.
Beck, PhD, Serge Przedborski, MD PhD, Stanley Fahn, MD, and Roy N. Alcalay, MD, MS
Online Resource
Supplementary Table 1. Commonly reported symptoms newly developed during COVID-19 illness Supplementary Figure 1. Patients with Parkinson’s disease and COVID-19 enrollment flowchart Supplementary Figure 2. COVID-19 related death distribution by age and gender
Supplementary Survey
CUIMC registry cohort
PF survey cohort
N (Yes, developed this symptom)
N (Total responses received)
*Percentage (yes/total) Common COVID-19 symptoms
Fatigue or Tiredness 31 38 81.6%
Fever or chills 31 45 68.9%
Weight loss 24 36 66.7%
Cough 28 44 63.6%
Body Temperature higher than 100.4 F or 38.0 C
16 35 45.7%
Muscle or body ache/pain 14 35 40.0%
Headache 13 34 38.2%
Chest congestion 13 35 37.1%
Shortness of breath 14 39 35.9%
Temporary loss of smell 10 35 28.6%
Sore throat 10 36 27.8%
Nausea 10 36 27.8%
Runny or stuffy nose 9 36 25.0%
Diarrhea 8 35 22.9%
Temporary loss of taste 8 36 22.2%
Urinary issues 5 27 18.5%
Abdominal discomfort 5 35 14.3%
Hair loss 5 35 14.3%
Dry skin 4 35 11.4%
Sneezing 3 35 8.6%
Vomiting 3 35 8.6%
Skin rash 2 35 5.7%
Neurological symptoms
Weakness 20 35 57.1%
Difficulty walking 11 25 44.0%
Dizziness 13 34 38.2%
Bradykinesia 9 25 36.0%
Confusion 11 37 29.7%
Other 10 35 28.6%
Anxiety 6 25 24.0%
Apathy 6 25 24.0%
Visual changes 8 34 23.5%
Rigidity 5 25 20.0%
Constipation 5 25 20.0%
Pain 5 25 20.0%
OFF time 4 24 16.7%
Memory Loss 4 25 16.0%
Falls 4 26 15.4%
Numbness/tingling 3 25 12.0%
Tremor 3 25 12.0%
Dyskinesia 3 25 12.0%
Double vision 3 34 8.8%
Hallucinations 2 26 7.7%
Tinnitus 2 34 5.9%
Facial twitches 2 34 5.9%
Loss of consciousness 1 33 3.0%
Body/Arms/Leg twitches 1 34 2.9%
Nerve pain 1 34 2.9%
Loss of sensation 1 34 2.9%
*
Not all participants responded to all symptom questions, this N represents the number of total responses
received for each question (including “Yes” and “No” answers).
Supplementary Figure 1. Patients with Parkinson’s disease and COVID-19 enrollment flowchart
Abbreviations: PD, Parkinson’s Disease; CUIMC, Columbia University Irving Medical Center; PF,
Parkinson’s Foundation
Supplementary Figure 2. COVID-19 related death distribution by age and gender
Age was stratified into 4 categories. Death due to COVID-19 was indicated in light grey, and those who are alive in dark grey. In the 61-70 age group, 1 male patient died because of COVID-19; in the 71-80 age group, 4 male and 1 female patient died because of COVID-19.
Supplementary Survey
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9 70/34<=++
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