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Figure S.1.Data flow diagram illustrating data management for developing the acute myocardial infarction (AMI), stroke and atrial fibrillation (AF) cohorts.

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Population

Excluding

AMI < 2014 n=98,454 AMI < 30 years: n=7

Excluding

Stroke < 2014: n=122,740 Stroke < 30 years: n=0

Excluding

AF < 2014: n=132,450 AF < 30 years: n=9

At risk of AMI

n=3,501,382 At risk of stroke

n=3,477,096 At risk of AF

n=3,467,377

Cases of acute myocardial infarction (AMI)

Excluding

Not resident 1.1 2014: n=688 Case < 30 years: n=0

Excluding

AMI after emigration: n=10 (Included as non-cases)

AMI cases n=18,349

Cases of stroke Cases of atrial

fibrillation (AF)

Excluding

Not resident 1.1 2014: n=233 Case < 30 years: n=0

Excluding

Not resident 1.1 2014: n=494 Case < 30 years: n=0

Excluding

Stroke after emigration: n=8 (Included as non-cases)

Excluding

AF after emigration: n=9 (Included as non-cases)

Stroke cases

n=28,006 AF cases

n=39,040 Residents ≥ 30 years

Denmark 1 January 2014 n=3,599,836

Incident AMI 2014-2015 (NPR) with valid PIN n=16,620

Fatal AMI 2014-2015 (RCD) with no AMI in NPR (ever) n=1,972

Incident stroke 2014-2015 (NPR) with valid PIN n=27,212

Fatal stroke 2014-2015 (RCD) with no stroke in NPR (ever) n=1,490

Incident AF 2014-2015 (NPR) with valid PIN n=38,713

Fatal AF 2014-2015 (RCD) with no AF in NPR (ever) n=830

Total number of incident AMI 2014-2015 n=18,592

Total number of incident stroke 2014-2015 n=28,702

Total number of incident AF 2014-2015

n=39,543

Included in population under risk of AMI n=18,359

Included in population under risk of stroke n=28,014

Included in population under risk of AF n=39,049

Figure S.1. Data flow diagram illustrating data management for developing the acute myocardial infarction (AMI),

stroke and atrial fibrillation (AF) cohorts.

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