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Chemical Composition and in-vitro Antimicrobial Activity of the Essential Oils of Three Greek Achillea Species

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Chemical Composition and in-vitro Antimicrobial Activity of the Essential Oils of Three Greek Achillea Species

Prokopios Magiatis

a

, Alexios-Leandros Skaltsounis

a

, Ioanna Chinou

a

and Serkos A. Haroutounian

b,

*

a Laboratory of Pharmacognosy, Department of Pharmacy, University of Athens, Zografou 15771, Greece

b Chemistry Laboratory, Agricultural University of Athens, Iera odos 75, Athens 11855, Greece. Fax +30-1-5 29 42 65. E-mail: sehar@aua.gr

* Author for correspondence and reprint requests

Z. Naturforsch.57 c,287Ð290 (2002); received October 29/November 30, 2001 Achillea sp., Essential Oil, Antimicrobial Activity

The chemical composition of the essential oils of Achillea holosericea, Achillea taygetea, Achillea fraasiiwas determined by GC/MS analysis. Among the ninety-five assayed constitu- ents, camphor, borneol and 1,8-cineol were found to be the major components. Thein-vitro antimicrobial activity of these essential oils was evaluated against six bacteria indicating that the first is totally inactive, while the other two possess moderate to strong activities mainly against the Gram negative strains. The essential oil ofA. fraasiiwas also active against the tested pathogenic fungi.

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