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9 S5 59 75 399 9 S5 59 75 399 9 S5 59 75 399 9

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9 S5 59 75 399 9 S5 59 75 399 9 S5 59 75 399 9 S5 59 75 399

9 S5 59 75 399

Frequency

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>59=0congruent 93F6S=

>59=0congruent 93F74=

>59=0congruent 9SF93=

>59=0congruent 9SFC5=

>59=0congruent 9SF99=

>59=0congruent 9SFS9=

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a b c d

e f g h

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Supplementary Figure S1.0DIAMOND0best0hit0NOG0is0representative0of0additional0hitsF0Histograms0 representing0the0distribution0of0percent0congruency0of0alignment0hits0to0the0best0hit0for0a0sample0of03969990 aligned0readsF0In0all0cases60the0majority0of0additional0hits0)>=59=w0are0congruent0with0the0best0hit0in0terms0of0 NOG0assignmentF000

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