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Chemical Composition and Antimicrobial Activity of European Propolis Ahmed G. Hegazi

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Chemical Composition and Antimicrobial Activity of European Propolis

Ahmed G. Hegazi

a,

*, Faten K. Abd El Hady

b

, Fayrouz A. M. Abd Allah

a

a Departments Parasitology and

b Chemistry ofNatural Products, National Research Center, Dokki, Giza, Egypt.

Fax: +2023370931. E-mail: ahmedgaffer@frcu.eun.eg and samira@mena.org.eg

* Author for correspondence and reprint request

Z. Naturforsch.55c,70Ð75 (2000); received September 17/November 10, 1999 Propolis, GC/MS, Polyphenols, Antimicrobial Activity

Three propolis samples from Austria, Germany and France were investigated by GC/MS, where eleven compounds were being new for propolis. The samples showed some similarities in their qualitative composition. Phenylethyl-trans-caffeate, benzyl ferulate and galangin were predominant in German propolis. Benzyl caffeate was predominant in French sample. Pino- cembrin was predominant in French and Austrian propolis andtrans-p-coumaric acid was predominant in all samples.

The antimicrobial activity against Staphylococcus aureus; Escherichia coli, and Candida albicans was evaluated. German propolis showed the highest antimicrobial activity against Staphylococcus aureusandEscherichia coli.While Austrian propolis has the highest activity against Candida albicans. French propolis was effective against all pathogens but less than German and Austrian propolis.

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