• Keine Ergebnisse gefunden

Four-component Synthesis of 1,3,4-Oxadiazole Derivatives from (N-Isocyanimino)triphenylphosphorane, (E)-Cinnamic Acids, Acetaldehyde and Secondary Amines

N/A
N/A
Info
Herunterladen
Protected

Academic year: 2022

Aktie "Four-component Synthesis of 1,3,4-Oxadiazole Derivatives from (N-Isocyanimino)triphenylphosphorane, (E)-Cinnamic Acids, Acetaldehyde and Secondary Amines"

Copied!
1
0
0

Wird geladen.... (Jetzt Volltext ansehen)

Jetzt herunterladen ( 1 Seite )

Volltext

(1)

Four-component Synthesis of 1,3,4-Oxadiazole Derivatives from (N-Isocyanimino)triphenylphosphorane, (E)-Cinnamic Acids, Acetaldehyde and Secondary Amines

Ali Ramazania, Yavar Ahmadib, and Fatemeh Zeinali Nasrabadic

aChemistry Department, Islamic Azad University, Zanjan Branch, P.O.Box 49195-467, Zanjan, Iran

bIslamic Azad University, Zanjan Branch, Young Researchers Club, Zanjan, Iran

cChemistry Department, Zanjan University, P.O.Box 45195-313, Zanjan, Iran Reprint requests to Dr.A.Ramazani.E-mail: aliramazani@gmail.com Z. Naturforsch.2011,66b,184 – 190; received October 13, 2010

The 1 : 1 iminium intermediate, generated by the addition of a secondary amine to acetalde- hyde is trapped by the (N-isocyanimino)triphenylphosphorane in the presence of an (E)-cinnamic acid derivative, leading to the formation of the corresponding iminophosphorane intermediate.Di- substituted 1,3,4-oxadiazole derivatives are formed via intramolecular aza-Wittig reaction of the iminophosphorane intermediates.The reactions were completed under neutral conditions at room temperature, and the corresponding disubstituted 1,3,4-oxadiazole derivatives were produced in ex- cellent yields.

Key words:(N-Isocyanimino)triphenylphosphorane, (E)-Cinnamic Acid, Acetaldehyde, 1,3,4-Oxadiazole,aza-Wittig Reaction, Secondary Amine

Referenzen

Jetzt herunterladen ( PDF - 1 Seite - 25.16 KB )

ÄHNLICHE DOKUMENTE

The partition function with the account of states with a single domain wall reads Z=Z0+δZ =e(N−1)βJh 1 + (N−1)e−2βJi

We can improve it slightly by considering the configurations where arbitrary number of single-spin domains are present and neglecting interaction between them.. This analogous to

The 2N section is from 2 N, 130 E to 2 N, 134 E and the 1N section is from 1 N, 130 E to 1 N, 135 E

We could not estimate the accuracy and precision of our dissolved oxygen data. We did not have enough equipment for an accurate measurement of dissolved oxygen. Since we

within the asthenosphere) by low-degrees melting of an enriched peridotitic source in the presence of CO2 [1]

Two major hypotheses are currently in debate: first, intraplate magmas are produced at depth (i.e. within the asthenosphere) by low-degrees melting of an enriched peridotitic source

Enantioselective Synthesis of 3-Substituted Indolines by Asymmetric Intramolecular Carbolithiation in the Presence of (-)-Sparteine

Enantioselective Synthesis of 3-Substituted Indolines by Asymmetric Intramolecular Carbolithiation in the Presence of ( - )-Sparteine.. Gema Sanz Gil and

Enantioselective Synthesis of 3-Substituted Indolines by Asymmetric Intramolecular Carbolithiation in the Presence of (-)-Sparteine

The resulting mixture was stirred at room temperature for 3h, after which time the solvent was removed, dissolved in a minimum amount of ether and was eluted down a flash column

A ruthenium racemisation catalyst for the synthesis of primary amines from secondary amines

A Ru-based half sandwich complex used in amine and alcohol racemization reactions was found to be active in the splitting of secondary amines to primary amines using NH 3..

Aminoallenylidene complexes of ruthenium(II) from the regioselective addition of secondary amines to butatrienylidene intermediates: a combined experimental and theoretical study of the hindered rotation around the CN-bond

This finds support from the X-ray structure analysis of the Z isomer of the (benzylmethyl)methylamine derivative 2d. Dynamic 3!p NMR spectroscopy gave a barrier of

(1)A CLUE TO THE DECIPHERMENT OF THE SO-CALLED SHELL SCRIPT By B

This stroke and also a curved line, issuing out ofthe loop of na,.. touch the