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Research Collection

Presentation

Modelling COVID19 using an agent-based-model of travel

Author(s):

Axhausen, Kay W.

Publication Date:

2021-04

Permanent Link:

https://doi.org/10.3929/ethz-b-000479837

Rights / License:

In Copyright - Non-Commercial Use Permitted

This page was generated automatically upon download from the ETH Zurich Research Collection. For more information please consult the Terms of use.

(2)

Preferred citation style

Axhausen, K.W. (2021) Modelling COVID19 using an agent-based-model of

travel, presentation at the Chinese University Hong Kong, online, April

2021.

(3)

Modelling COVID19 using an agent-based-model of travel

KW Axhausen IVT

ETH Zürich

April 2021

(4)

Collaborators and partners NFP78

ETH Zürich

• M Balac

• G Kagho

• S Pennazi

• A Sallard

ETH Zürich (Thomas van Boeckel) FHNW (Erath Alexander)

University Basel (Melissa Penny) University Geneve (Olivia Keiser) Senezon (Michael Balmer)

Kai Nagel (TU Berlin), Zbigniew Smoreda (ORANGE), Sebastian

Bonhoeffer (ETH Zürich)

(5)

Acknowledgements

Sebastian Müller, TU Berlin

Stefano Penazzi, ETH Zürich

Joseph Molloy, ETH Zürich

(6)

COVID19 in Switzerland – Some numbers

(7)

MOBIS/COVID19 sample since March 2020

(8)

Share of mobile persons by day since September 2019

0 100 200 300 400

0%

25%

50%

75%

100%

0 28 56 84 112 140 168 196 224 252 280 308 336 364

N ew c o n fi rm ed h o sp ti al iz ed c as es

M o b ile p e rs o n s [% ]

Day of year

MOBIS control group COVID19 2020

COVID19 2021

Hospital cases 2021

Hospital cases 2020

(9)

Average number of trips and size of activity space by week

0.0 1.0 2.0 3.0 4.0 5.0 6.0

0.0 100.0 200.0 300.0 400.0 500.0

02.03 02.05 02.07 02.09 02.11 02.01 02.03

N u m b er o f tr ip s/ d ay

A ct iv it y sp ac e [k m 2 ]

Week starting with Monday

Weekday - Activity space

Weekend&holidays

Weekday - Trips

Weekend&holidays

(10)

Δ% change in PKm by mode: All by week

-100.0%

-50.0%

0.0%

50.0%

100.0%

150.0%

02 .0 9 .1 9 02 .1 0 .1 9 02 .1 1 .1 9 02 .1 2 .1 9 02 .0 1 .2 0 02 .0 2 .2 0 02 .0 3 .2 0 02 .0 4 .2 0 02 .0 5 .2 0 02 .0 6 .2 0 02 .0 7 .2 0 02 .0 8 .2 0 02 .0 9 .2 0 02 .1 0 .2 0 02 .1 1 .2 0 02 .1 2 .2 0 02 .0 1 .2 1 02 .0 2 .2 1 02 .0 3 .2 1

% c h an ge

Week starting

Bike

Walking

Bus

Tram

Train

Car

All

(11)

Δ% change in PKm by mode: Cycling and train by period

-100%

-50%

0%

50%

100%

150%

1 5 9 13 17 21 25 29 33 37 41 45 49 53

C h an ge

Caledar week

Bicylce before B2020

B2021 Train before T2020

T2021

(12)

How to assess the measures against a pandemic ?

(13)

How to assess ..? Model types

• Aggregate SEIR (Susceptible-Exposed-Infectious-Removed)

• Agent-based with contact networks SEIR

• Aggregate networks of co-presence in vehicles

• Repeated networks of co-presence based on agent-based transport

models

(14)

How to assess ..? Model types

• Repeated networks of co-presence based on agent-based transport models

Smieszek, T., M. Balmer, J. Hattendorf, K.W. Axhausen, J. Zinsstag and R.W. Scholz (2011) Reconstructing the 2003/2004 H3N2 influenza

epidemic in Switzerland with a spatially explicit, individual-based

model, BMC infectious diseases, 11 (1) 1-18.

(15)

How to assess ..? Networks of co-presence

Co-presence is defined by

• A space

• A starting time

• A joint duration

• Other persons present for the joint duration

(16)

How to assess ..? Networks of co-presence

Time

(17)

How to assess ..? MATSim

MATSim delivers

• An agent-population

• The network of co-presence for one day (at activities and “in vehicle”)

• The computing infrastructure to replan the days

(18)

How to does MATSim generate the days?

MATSim calculates the equilibrium pipelines for scenario generation for reproducibility

• OSM reader

• GTFS + transit network mapping

• Population synthesis (incl variant for GSM data use)

(19)

Tools inside the open-source framework MATSim

Pipelines for scenario generation for reproducibility

• OSM reader

• GTFS + transit network mapping

• Population synthesis (inc. variant for GSM data use)

• Sallard’s traffic signal imputation Faster implementations

• Hörl/Balac’s eqasim (RUM mode choice)

• HERMES for MobSim

• Penazzi’s DEDALO to form super-networks

• Flötteröd’s OPTYTS for parameter calibration External commercial products

• VIA for result analysis

• TRAMOLA for scenario editing and run management

(20)

How to assess ..? Simple measures

Prohibit or limit co-presence by

• Quarantine

• Home-office; home-schooling

• Limits on group size

• Range restrictions

(21)

How to assess ..? Episim’s infection model

episim delivers

• Repeated instances of the same day

• Tracing of the person and its health status over the days

• Possible infections during joint activities

• Simple measures by removing the affected agents from the

activities

(22)

How to assess ..? Episim’s infection model

episim assumes a random process among N randomly chosen agents:

𝑃

𝑖𝑛𝑓𝑒𝑐𝑡𝑖𝑜𝑛

= 1 − 𝑒

− ΘContactIntensity ・Shedding・Intake・Duration・Susceptibility・ Infectivity・OutdoorFactor

• ContactIntensity ∼ Flow per agents

• Shedding, Intake = 1, unless mask wearing

• Duration = Activity time from MATSim

• Susceptibility, Infectivity = 1, but reduced for children

• OutdoorFactor = 1, unless outdoor activity, e.g. dining

(23)

How to assess ..? Progression process after infection

Exposed Infectious

Symptomatic

Seriously sick Critical

Seriously sick

Recovered

Recovered

Recovered

Recovered

[3.5 (3.5)]

[2.0 (2.0)]

[4.0 (4.0)]

[1.0 (1.0)]

[21.0 (21.0)]

[4.0 (4.0)]

[8.0 (8.0)]

[14.0 (14.0)]

[3.5 (3.5)]

[7.0 (7.0)]

[Median (st. dev.)]

(24)

Switzerland implementation

Calibrated model, well used in previous projects

• OSM network

• Public transport timetables (SBB and all regional providers)

• STATPOP population (registry data)

• Travel diaries (Microzensus 2015)

• Validated against counts, modes*distance

(25)

Switzerland: Mask adoption factor

(26)

Switzerland: Imported cases (calibrated)

Infectiousness

• SARS_COV_2 = 1.0

• B.1.1.7 = 1.5

• B.1.351 = 1.5

• P.1 = 1.5

(27)

Switzerland: Calibrated model results

(28)

Switzerland: Seriously sick by example region (canton)

(29)

Switzerland: Average ICU cases by hospital

(30)

Switzerland: Vaccination strategy – ICU patients

3000 6000 9000 12000

Persons/day

(31)

Next steps: Hypertension + diabetes

Age

(32)

Next steps: Capabilities

Available data

• UK data for weekly and household interactions

• Identifying large events Methodology

• Pipeline modification for detailed activity types and location assignment

• Bayesian network for generating household interactions and weekly activity patterns

• Modelling of large (superspreader) events

• Updating of the illness progression and population

(33)

Questions?

ETH Zürich:

www.ivtmobis.ethz.ch/mobis/covid19 www.ivt.ethz.ch

TU Berlin:

covid-sim.info

github.com/matsim-org/matsim-episim

www.matsim.org

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