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Article title: Chronic comorbidities and clinical outcomes in patients with and without COVID-19: A large population-based study using national administrative healthcare open data of Mexico.

Journal name: Internal and Emergency Medicine.

Author names: Frank Daniel Martos-Benítez, Caridad de Dios Soler-Morejón, Diana García-del Barco.

Corresponding author: Frank Daniel Martos-Benítez; Intensive Care Unit 8B, Hermanos Ameijeiras Hospital, 702 San Lázaro St., Havana Centre, Havana City 10300, Cuba; email: fdmartos@infomed.sld.cu

Electronic Supplementary Material 2 Flow chart of participants.

1

Patients with

suspicion of viral respiratory disease

n = 65,535

SARS-CoV-2 negative n = 27,211 (41.5%) SARS-CoV-2 positive

n = 38,324 (58.5%)

Contact of COVID-19 patients Yes = 10,498 (46.2%)

No = 12,219 (31.9%)

Unknown = 15,607 (40.7%)

Contact of COVID-19 patients Yes = 5,880 (21.6%)

No = 6,714 (24.7%)

Unknown = 14,617 (53.7%)

Chronic comorbidities Yes = 10,713 (39.4%) No = 16,423 (60.4) Unknown = 75 (0.3) Chronic comorbidities

Yes = 17,955 (46.9%)

No = 19,883 (51.9%)

Unknown = 486 (1.3)

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Corresponding author: Frank Daniel Martos-Benítez; Intensive Care Unit 8B, Hermanos Ameijeiras Hospital, 702 San Lázaro St., Havana Centre, Havana City 10300, Cuba;