Sequenzen ab Exon 46 des felinen PKD1-Gens bis im Exon 40 des felinen TSC2-Gens

Anhang 178 Sequenz der Probe D3142

>GATC1-N43F.abi;

1 CG CGCCGCRCAG TCCGGAGCCT GGGCGCGGTG GCTGCTGGTG GCCCTGACCG 61 CGGCCGCGGC GCTCGTGCGC CTGGCCCAGC TGGGTGTCGC CGACCGCCAG TGGACCCGCT 121 TCGTGCGCCG CCGCCCGCGC CGCTTCACCA GCTTCGAGCA GGTGGCGCAG CTGAGCTCCG 181 CGGCTCGCGG CCTGGCCGCC TCGCTGCTCT TTCTCCTGCT GGTCAAGGTG AGGGCTGGGC 241 CGGCGGGGGT CGGCCGGGGC CTGGGCCGGG CCGGGTCGAA CCGGCGGCGG TTCGGTCAAC 301 CGACACCGCT CGCCCCCAGG CCGCCCAGCA GCTGCGCTTC GTGCGCCAGT GGTCGGTTTT 361 CGGCAAGACG CTGTACAGGG CCCTGCCGGA GCTCGTGGGC GCGGCCTTGG GCCTGGTGGT 421 GCTCGCCGTG GCTTATGCCC AGCTGGCCAT TCTGGTAGGT GGCGGCGAGG CCGTCAGGGG 481 AGGGG

>N+43-43F.abi;

1 ACGCG CGCCGCRCAG TCCGGAGCCT GGGCGCGGTG GCTGCTGGTG GCCCTGACCG 61 CGGCCGCGGC GCTCGTGCGC CTGGCCCAGC TGGGTGTCGC CGACCGCCAG TGGACCCGCT 121 TCGTGCGCCG CCGCCCGCGC CGCTTCACCA GCTTCGAGCA GGTGGCGCAG CTGAGCTCCG 181 CGGCTCGCGG CCTGGCCGCC TCGCTGCTCT TTCTCCTGCT GGTCAAGGTG AGGGCTGGGC 241 CGGCGGGGGT CGGCYGGGGC CTGGGCCGGG CCGGGTCGAA CCGGCGGCGG TTCGGTCAAC 301 CGACACCGCT CGCCCCCAGG CCGCCCAGCA GCTGCGCTTC GTGCGCCAGT GGTCGGTTTT 361 CGGCAAGACG CTGTACAGGG CCCTGCCGGA GCTCGTGGGC GCGGCCTTGG GCCTGGTGGT 421 GCTCGCCGTG GCTTATGCCC AGCTGGCCAT TCTGGTAGGT GGCGGCGAGG CCGTCAGGGG 481 AGGGGGGGCT CAGCCCGGGA CGCGCCCCTC ACGCGCGCCC CTTCCCCTTG CAGCTGGTCG 541 CTTCCTGCGT GGACTCGTTT CGGAGCGCCC TGAGGGCCGT CTTGGTGCCG TGTCCCGGGT 601 CTGGGGGTCC TGCCCCGTGC CCTGCCGAGT CCTGGCGCCT CTCCCCGCTG CTGTGCACTG 661 GGCTCTGGGC GCTGCGGCTG TGGGGGGCCC TGAGGCTGGG GGCGGTCCTC CTGCG

>N+43-46R.abi;

481 CGCGCGCCC CTTCCCCTTG CAGCTGGTCG 541 CTTCCTGCGT GGACTCGTTT CGGAGCGCCC TGAGGGCCGT CTTGGTGCCG TGTCCCGGGT 601 CTGGGGGTCC TGCCCCGTGC CCTGCCGAGT CCTGGCGCCT CTCCCCGCTG CTGTGCACTG 661 GGCTCTGGGC GCTGCGGCTG TGGGGGGCCC TGAGGCTGGG GGCGGTCCTC CTGCGGTGGC 721 GGTACCACGC GCTGCGTGGG GAGCTTTACC GGCCGGCCTG GGAGCCGCAG GACTACGAGA 781 TGGTGGAGCT GTTYTTGCGC CGGCTGCGCC TYTGGATGGG CTTCAGTAAG GTTAAGGAGG 841 TGGGTACGGC CCAGTGGGGG GGAGAGGGAC GCACCCTGGG CCCAGGGGAG CCCGGGGTGC 901 AGCCGGACTG ACGGAGCCCC TGTGCCGCCC CCAGTTCCGT YACAAAGTCC GGTTTGAAGG 961 GATGGAACCG CTGCCCTCRC GCTCCTCCAG GGGCTCCAAG TCGTCCCCGG ACGCACCCCC 1021 CCCCAGTGGG GGCTCAGACG CCTCCCGGCC CTCCACGGCC TCCAGCCAGC TGGACACACC 1081 CGGCGGGGGC CTGAGCCGGC TGGGGCCGCG TGGGGAGCC

8.5.2.6 Sequenzen ab Exon 46 des felinen PKD1-Gens bis im Exon 40 des felinen

Vergleichsequenz für die mit Primer TSC-R sequenzierten PCR-Produkte

>Reference File(s) : backlon PKD-TSC-R_F_Synthesis_358.scf;

1 CCCGCCCCCG CTCCTTCCTG AAGGCTCCCC GTCCCCTGCA GATCCGTGAG GAAGCCCACT 61 ACTCCAACCC CAGCCTGCCG CTGACGCAGA CGCACCCTCC GGGCCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCC GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC GGGGGGCCAC CCTGCCACCA CCCACGTGTT CTCCGGTGCA CAGACCCTCA 421 CCTGCCCCAG CCCCGGGAGC CAGCCCCGGG GCAGGGCTGC TTCCACCCTG GAGTTCTGGC 481 CCCGCCCGCG TCCTCCTCCT CCCCCAGACC TGACACCCGC GGGTCTGGGC TCTGCCCTCT 541 TGCTGTCACA GCCCAGGCAG AGAGCAAGGC CGTGGGGGTG GGGAGGGGGG TGGTGACAGG 601 AAGTGCCGAG GCGATGGCTG GGCCCTTCCA ACAAGCCTCC CATCCCAGCC CCAGGCCCAA 661 CTTGGATCCA ACTCTGGTTA GGTGTCTGGG GAGGGAGGCC AGCGCTGCAG CCCCAGCACC 721 CCTTCCCA

Sequenz der Probe D2573

>73-TSC-F.abi;

121 CAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGCTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCAGAGGC TTCAGAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA GACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AAGAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC ARACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCARAGGG AGCCAGAGCA GACCCCGTTC AGTATTAATT TCTGCCACCC 601 TTACGGTCTC GGGCCAGGCA GAAGAGCTGC ACGAAGGCCC CCAGGGAGCA GTCGTCTCTC 661 TCTCTGTGGG TCTCAGCACT TTAAAGACGC CATGTGGGCA GCCAGGACCC AGGGTCCCCT

>73-TSC-R.abi;

61 CACCCTCC GGGCCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCT GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC GGGGGGCCAC CCTGCCACCA CCCACGTGTT CTCCCTGCCA CCACCCACGT 421 GTTCTCCGGT GCACAGACCC TCACCTGCCC CAGCCCCGGG AGCCAGCCCC GGGGCAGGGC 481 TGCTTCCACC CTGGAGTTCT GGCGCCGCCC GCGTCCTCCT CCTCCCCCAG ACCTGACACC 541 CGCGGGTCTG GGCTCTGCCC TCTTGCTGTC ACAGCCCAGG CAGAGAGCAA GGCCGCGGGG 601 GTGGGGAGGG GGGTGGTGAC AGGAAGTGCC GAGGCGATGG CTGGGCCCTT CCAACAAGCC 661 TCCCATCCCA RCCYCAGGCC CAACTTGGAT CCAACTCTGG TTAGGTGTCT GGGGAGGGAG 721 GCCAGCGCTG CAGCCCCAGC ACCCCTTCCC

Sequenz der Probe D2582

>82-TSC-F.abi;

61 AAGTCGTCCC CGGACGCACC 121 CCCCCCCAGT GGGGGCTCAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGCTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCAGAGGC TTCARAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA GACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AARAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC ARACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCAGAGGG AGCCAGAGCA GACMCCGCTC AGTATTAATT TCTGCCACCC 601 TTACGGTCTC GGGCCAGGCA GAAGAGCTGC ACGAAGGCCC CCAGGGAGCA GTCGTCT

Anhang 180

>82-TSC-R.abi;

61 CGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCT GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC GGGGGGCCAC CCTGCCACCA CCCACGTGTT CTCCCTGCCA CCACCCACGT 421 GTTCTCCGGT GCACAGACCC TCACCTGCCC CAGCCCCGGG AGCCAGCCCC GGGGCAGGGC 481 TGCTTCCACC CTGGAGTTCT GGCGCCGCCC GCGTCCTCCT CCTCCCCCAG ACCTGACACC 541 CGCGGGTCTG GGCTCTGCCC TCTTGCTGTC ACAGCCCAGG CAGAKAGCAA GGCCGCGGGG 601 GTGGGGAGGG GGGTGSTGAC AGGAAGTGYC GAGGCGATGG CTGGGCCCTT CCAACAAGCC 661 TCCCATCCCA GCCCCAGGCC CAAMTTGGAT CCAACTCTGG TTAGGTGTCT GGKGAGGGAG 721 GCC

Sequenz der Probe D2598

>98-TSC-F.abi;

61 CC AAGTCGTCCC CGGACGCACC 121 CCCCCCCAGK GGGGGCTCAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGYTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCAGAGGC TTCAGAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA GACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AAGAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC AGACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCAGAGGG AGCCAGAGCA GACMCCGCTC AGTA

>98-TSC-F2.abi;

241 C TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCARAGGC TTCARAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA RACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AARAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC AGACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCARAGGG AGCCAGAGCA GACMCCGYTC AGTATTAATT TCTGCCACCC 601 TTACGGTCTC GGGCCAGGCA GAAGAGCTGC ACGAAGGCCC CCAGGG

>98-TSC-R.abi;

61 CACCCTCC GGGCCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCY GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC

Sequenz der Probe D2004

>TSC04-TSCF.abi;

61 AAGTCGTCCC CGGACGCACC 121 CCCCCCCAGT GGGGGCTCAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGCTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCARAGGC TTCARAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA RACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AARAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC ARACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCARAGGG AGCCAGAGCA GACCCCGTTC AGTATTAATT TCTGCCACCC 601 TTACGGTCTC GGGCCAGGCA GAAGAGCTGC ACGAAGGCCC CCAGGGAGCA GTCGTCTCTC 661 TCTCTSTGGG TCTCAGCACT TTAAAGACGC CATGTGGGCA GCCAGGACCC AGGGTCCCCT

>TSC04-TSCR.abi;

61 TCC GGGCCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCT GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC GGGGGGCCAC CCTGCCACCA CCCACGTGTT CTCCGGTGCA CAGACCCTCA 421 CCTGCCCCAG CCCCGGGAGC CAGCCCCGGG GCAGGGCTGC TTCCACCCTG GAGTTCTGGC 481 CCCGCCCGCG TCCTCCTCCT CCCCCAGACC TGACACCCGC GGGTCTGGGC TCTGCCCTCT 541 TGCTGTCACA GCCCAGGCAG AGAGCAAGGC CGTGGGGGTG GGGAGGGGGG TGGTGAC

>GATC1-TSC04-TSCR.abi;

121 ACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCT GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACACCCAC GGAGGTGGTA CAGGGCCTGT CGGGCTGCGG TCGGGGGCCA TCCTGCCACC 421 ACCCACGTGT TCTCCCTGCC ACCACCCACG TGTTCTCCGG TGCACAGACC CTCACCTGCC 481 CCAGCCCCGG GAGCCAGCCC CGGGGCAGGG CTGCTTCCAC CCTGGAGTTC TGGCGCCGCC 541 CGCGTCCTCC TCCTCCCCCA GACCTGACAC CCGCGGGTCT GGGCTCTGCC CTCT

Sequenz der Probe D2577

>TSC77-TSCF.abi;

61 AAGTCGTCCC CGGACGCACC 121 CCCCCCCAGT GGGGGCTCAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGCTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCARAGGC TTCARAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA RACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 GGGTCTGGCC CCGGGCCCCT GCAGGGTTTC CCTGCGGGCT AARAACAAGG TCCACCCCGG 481 CAGCACTTAG TCCCGGGGGG TCCCGGGCTC ARACCCCTTC CCTGGGGTGG TCCTCTGGCT 541 TCAGTCCCCT CTGCAGAGGG AGCCAGAGCA GACMCCGYTC AGTATTAATT TCTGCCACCC 601 TTACGGTCTC GGGCCAGGCA GAAGAGCTGC ACGAAGGCCC CCAGGGAGCA GTCGTCTCTC 661 TCTCTSTGGG TCTCAGCACT TTAAAGACGC CATGTGGGCA GCCAGGACCC AGGGTCCCC

>GATC1-TSC77-TSCR.abi;

121 GCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCY GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACA

>TSC77-TSCR.abi;

121 GCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCGGGTCCC GTGCCCCGCY GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATC

Sequenz der Probe D3142

>N+TSCF.abi;

61 ACGCACC 121 CCCCCCCAGT GGGGGCTCAG ACGCCTCCCG GCCCTCCACG GCCTCCAGCC AGCTGGACAC 181 ACCCGGCGGG GGCCTGAGCC GGCTGGGGCC GCGTGGGGAG CCCGAGCCCT CTCGTCTCCA 241 GGCCGTGTTC GAGGCCCTTC TGACCCAGTT CGACCGACTC AACCAGGCCA CGGAGGATGT 301 CTACCAGCTG GAGCAGAGGC TTCARAGCCT GCAAGGCCGC AGGAGCACGG GTGCCCACAG 361 CCCCTCCTCA RACCTGCGGC CGGCCCTGCC TGGCCGTCTT GCCCGGGCCA GTCGTGGCGT 421 G

Anhang 182

> N+TSC-TSCR.abi;

61 TCC GGGCCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCRGGTCCC GTGCCCCGCY GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACRCCCAC GG

>GATC1-N+TSCR.abi;

61 CCACGCC AAGGCCCCGG 121 CCGAGCCCAC GCCCACGTAC GAGACGGGCC AGCGGAAGCG CCTCATCTCC TCTGTGGATG 181 ACTTCACCGA GTTCGTGTGA GCCRGGTCCC GTGCCCCGCY GTTATATGCG CAAATGAAAT 241 AAAGCAGTGG TGCAGCCCCG GCCTCCCCAT CGTGTCACTC AGAGCCAGAC GCGGATGCAG 301 TCAGCCAGCT GGTTTATTTG ACTTTGTCGG GTGGGGATGG GATCAAGGCT GTAGCTATGG 361 CCACRCCCAC GG