Alessandri-Haber N, Dina OA, Joseph EK, Reichling D, Levine JD (2006). "A transient receptor potential vanilloid 4-dependent mechanism of
hyperalgesia is engaged by concerted action of inflammatory mediators."
J Neurosci 26: 3864-3874.
Alessandri-Haber N, Joseph E, Dina OA, Liedtke W, Levine JD (2005). "TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator." Pain 118: 70-79.
Alessandri-Haber N, Yeh JJ, Boyd AE, Parada CA, Chen X et al (2003).
"Hypotonicity induces TRPV4-mediated nociception in rat." Neuron 39:
497-511.
Alvarez D, King JA, Weber D, Addison E, Liedtke W, Choe Y, Marti-Renom MA, Bell AM, Denis CS (2006). "Transient receptor potential vanilloid
4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury." Circ Res 99: 988-995.
Andrade Y, Fernandes J, Vazquez E, Fernandez-Fernandez JM, Arniges M et al (2005). "TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity." J Cell Biol 168: 869-874.
Arniges M, Fernández-Fernández JM, Albrecht N, Schaefer M, Valverde MA, (2005). "Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking." J Biol Chem 281:
1580.
Arniges M, Vázquez E, Fernández-Fernández JM, Valverde MA (2004).
"Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia." J Biol Chem 279: 54062.
Bellien J, Iacob M, Gutierrez L, Isabelle M, Lahary A, Thuillez C, Joannides R (2006). "Crucial role of NO and endothelium-derived hyperpolarizing factor in human sustained conduit artery flow-mediated dilation."
Hypertension 48: 1088-1094.
Birder L, Kullmann FA, Lee H, Barrick S, de Groat W, Kanai A, Caterina M (2007). "Activation of Urothelial Transient Receptor Potential Vanilloid 4 by 4alpha-Phorbol 12,13-Didecanoate Contributes to Altered Bladder Reflexes in the Rat." JPET 323:227-235.
Birnbaumer L, Yidirim E, Abramowitz J (2003). "A comparison of the genes coding for canonical TRP channels and their M, V and P relatives." Cell Calcium 33, 419-432.
Bredt D, Snyder SH (1990). "Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme." Proc Natl Acad Sci USA 87: 682-685.
Busse R, Edwards G, Félétou M, Fleming I, Vanhoutte PM, Weston AH (2002).
"EDHF: Bringing the concepts together." Trends Pharmacol Sci 23: 374-380.
Caterina M (2007). "Transient receptor potential ion channels as participants in thermosensation and thermoregulation." Am J Physiol Regul Integr Comp Physiol 292: R64-76.
Chung M, Lee H, Caterina MJ (2003). "Warm temperatures activate TRPV4 in mouse 308 keratinocytes." J Biol Chem 278: 32037-32046.
Clapham D (2003). "TRP channels as cellular sensors." Nature 426: 517-524.
65 Clapham D, Montell C, Schultz G, Julius D (2003). "International Union of
Pharmacology. XLIII. Compendium of voltage-gated ion channels:
transient receptor potential channels." Pharmacol Rev 55: 591-596.
Cohen D (2007). The Role of TRPV4 in the Kidney. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S. Boca Raton, FL, CRC Press: 397-412.
Cohen D (2007). "The transient receptor potential vanilloid-responsive 1 and 4 cation channels: role in neuronal osmosensing and renal physiology."
Current Opinion in Neurobiology, 16:451-458.
Delany N, Hurle M, Facer P, Alnadaf T, Plumpton C, Kinghorn I, See CG, Costigan M, Anand P, Woolf CJ, Crowther D, Sanseau P, Tate SN (2001). "Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2." Physiol Genomics 4: 165-174.
Dietrich A, Mederos M, Gollasch M, Gross V, Storch U, Dubrovska G, Obst M, Yildirim E, Salanova B, Kalwa H, Essin K, Pinkenburg O, Luft F,
Gudermann T, Birnbaumer L (2005). "Increased Vascular Smooth Muscle Contractility in TRPC6-/- Mice." Molecular and Cellular Biology:
25.16: 6980-6989.
Earley S, Heppner TJ, Nelson MT, Brayden JE (2005). "TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels."
Circ Res 97: 1270-1279.
Earley S, Reading S, Brayden J (2007). Functional Significance of Transient Receptor Potential Channels in Vascular Function. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. W.
Liedtke, Heller, S. Boca Raton, FL, CRC Press: 361-376.
Eichler I, Wibawa J, Grgic I, Knorr A, Brakemeier S et al (2003). "Selective blockade of endothelial Ca2+-activated small- and
intermediate-conductance K+-channels suppresses EDHF-mediated vasodilation." Br J Pharmacol 138: 594-601.
Erler I, Hirnet D, Wissenbach U, Flockerzi V, Niemeyer BA (2004). "Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat." J Biol Chem 279: 34456-63.
Falcone J, Kuo L, Meininger GA (1993). "Endothelial cell calcium increases during flow-induced dilation in isolated arterioles." Am J Physiol 264:
H653-659.
Feletou M, Vanhoutte PM (2006). "Endothelium-derived hyperpolarizing factor:
where are we now?" Arterioscler Thromb Vasc Biol 26: 1215-1225.
Fleming I, Bauersachs J, Fisslthaler B, Busse R (1998). "Ca2+-independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress." Circ Res 82: 686-695.
Flockerzi V (2007). "An introduction on TRP channels." Handb Exp Pharmacol:
1-19.
Freichel M, Suh SH, Pfeifer A, Schweig U, Trost C, Weissgerber P, Biel M, Philipp S, Freise D, Droogmans G, Hofmann F, Flockerzi V, Nilius B (2001). "Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice." Nat Cell Biol 3: 121-127.
Furchgott R, Zawadzki JV (1980). "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine." Nature 288: 373-376.
66 Gao X, Wu L, O'Neil RG (2003). "Temperature-modulated diversity of TRPV4
channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways." J Biol Chem 278: 27129-27137.
Gaudet R (2007). Structural Insights into the Function of TRP Channels. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S. Boca Raton, FL, CRC Press: 349-360.
Gevaert T, Vriens J, Segal A, Everaerts W, Roskams T, Talavera K, Owsianik G, Liedtke W, Daelemans D, Dewachter I, van Leuven F, Voets T, de Ridder D, Nilius B (2007). "Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding." J Clin Invest 117:
3453-3462.
Grant A, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P (2007). "Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice." J Physiol 578:
715-733.
Griffith T (2004). "Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?" Br J Pharmacol 141: 881-903.
Guatteo E, Chung KK, Bowala TK, Bernardi G, Mercuri NB, Lipski J (2005).
"Temperature sensitivity of dopaminergic neurons of the substantia nigra pars compacta: involvement of TRP channels." J Neurophysiol 94: 3069-3080.
Güler A, Lee H, Iida T, Shimizu I, Tominaga M et al (2002). "Heat-evoked activation of the ion channel, TRPV4." J Neurosci 22: 6408-6414.
Halaszovich C, Zitt C, Jüngling E, Lückhoff A (2000). "Inhibition of TRP3
Channels by Lanthanides." The Journal of Biological Chemistry, 275, 48, pp. 37423-37428.
Harteneck C, Plant TD, Schultz G (2000). "From worm to man: three subfamilies of TRP channels." Trends Neurosci 23: 159-166.
Hellwig N, Albrecht N, Harteneck C, Schultz G, Schäfer M (2005). "Homo- and heterometric assembly of TRPV channel subunits." J Cell Sci 118: 917-928.
Helmlinger G, Berk BC, Nerem RM (1996). "Pulsatile and steady flow-induced calcium oscillations in single cultured endothelial cells." J Vasc Res 33:
360-369.
Hofmann T, Schaefer M, Schultz G, Gudermann T (2002). "Subunit composition of mammalian transient receptor potential channels in living cells." Proc Natl Acad Sci USA 99: 7461-7466.
Holtz J, Förstermann U, Pohl U, Giesler M, Bassenge E (1984).
"Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition." J Cardiovasc Pharmacol 6: 1161-1169.
Hoyer J, Köhler R, Distler A (1997). "Mechanosensitive cation channels in aortic endothelium of normotensive and hypertensive rats." Hypertension 30:
112-119.
Hoyer J, Köhler R, Distler A (1998). "Mechanosensitive Ca2+ oscillations and STOC activation in endothelial cells." Faseb J 12: 359-366.
67 Hoyer J, Köhler R, Haase W, Distler A (1996). "Up-regulation of
pressure-activated Ca2+-permeable cation channel in intact vascular endothelium of hypertensive rats." Proc Natl Acad Sci USA 93: 11253-11258.
Hsu Y, Hoenderop JGJ, Bindels RJM (2007). "TRP channels in kidney disease."
Biochimica et Biophysica Acta 1772: 928-936.
Ishii T, Silvia C, Hirschberg B, Bond CT, Adelman JP, Maylie J (1997). "A human intermediate conductance calcium-activated potassium channel."
Proc Natl Acad Sci USA 94: 11651-11656.
Jia Y, Wang X, Varty L, Rizzo CA, Yang R, Correll CC, Phelps PT, Egan RW, Hey JA (2004). "Functional TRPV4 channels are expressed in human airway smooth muscle cells." Am J Physiol Lung Cell Mol Physiol 287:
L272-278.
Jian M, King JA, Al-Mehdi AB, Liedtke W, Townsley MI (2007). "High Vascular Pressure-Induced Lung Injury Requires P450 Epoxygenase-Dependent Activation of TRPV4." Am J Respir Cell Mol Biol 38: 386-392.
Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C, Lüscher TF (1995). "Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo." Circulation 91: 1314-1319.
Köhler M, Hirschberg B, Bond CT, Kinzie JM, Marrion NV, Maylie J, Adelman JP (1996). "Small-conductance, calcium-activated potassium channels from mammalian brain." Science 273: 1709-1714.
Köhler R, Brakemeier S, Kühn M, Behrens C, Real R et al (2001). "Impaired hyperpolarization in regenerated endothelium after balloon catheter injury." Circ Res 89: 174-179.
Köhler R, Degenhardt C, Kühn M, Runkel N, Paul M, Hoyer J (2000).
"Expression and function of endothelial Ca2+-activated K+ channels in human mesenteric artery: a single-cell reverse
transcriptase-polymersase chain reaction and electrophysiological study in situ." Circ Res 87: 496-503.
Köhler R, Heyken WT, Heinau P, Schubert R, Si H et al (2006). "Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation." Arterioscler Thromb Vasc Biol 26: 1495-1502.
Köhler R, Hoyer J (2007). "The endothelium-derived hyperpolarizing factor:
insights from genetic animal models." Kidney Int Apr 25; [Epub ahead of print]; doi:10.1038/sj.ki.5002303.
Köhler R, Hoyer J (2007). Role of TRPV4 in the Mechanotransduction of Shear Stress in Endothelial Cells. TRP Ion Channel Function in Sensory
Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S.
Boca Raton, FL, CRC Press: 377-388.
Lansman J, Hallam TJ, Rink TJ (1987). "Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?" Nature 325: 811-813.
Lee H, Iida T, Mizuno A, Suzuki M, Caterina MJ (2005). "Altered thermal
selection behavior in mice lacking transient receptor potential vanilloid 4."
J Neurosci 25: 1304-1310.
Leffler A, Linte RM, Nau C, Reeh P, Babes A (2007). "A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium." European Journal of
Neuroscience, Vol. 26, pp. 12-22.
68 Liedtke W (2007). "TRPV channels' role in osmotransduction and
mechanotransduction." Handb Exp Pharmacol: 473-487.
Liedtke W (2007). TRPV Channels´ Function in Osmo- and
Mechanotransduction. TRP Ion Channel Function in Sensory
Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S.
Boca Raton, FL, CRC Press: 303-318.
Liedtke W, Choe Y, Marti-Renom MA, Bell AM, Denis CS (2000). "Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor." Cell 103: 525-535.
Liedtke W, Friedman JM (2003). "Abnormal osmotic regulation in trpv4-/- mice."
Proc Natl Acad Sci USA 100: 13698-13703.
Liedtke W, Kim C (2005). "Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon!" Cell Mol Life Sci 62: 2985-3001.
Loot A, Popp R, Fisslthaler B, Vriens J, Nilius B, Fleming I. (2008). "Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation." Cardiovasc Res.
Maroto R, Raso A, Wood TG, Kurosky A, Martinac B, Hamill OP (2005).
"TRPC1 forms the stretch-activated cation channel in vertebrate cells."
Nat. Cell. Biol., 7, 179-185.
Marrelli S, O'Neil RG, Brown RC, Bryan RMJr (2007). "PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries." Am J Physiol Heart Circ Physiol 292: H1390-1397.
Moncada S GR, Bunting S, Vane JR (1976). "An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation." Nature 263: 663-665.
Montell C (2005). "The TRP superfamily of cation channels." Sci STKE 2005:
re3.
Montell C, Birnbaumer L, Flockerzi V (2002). "The TRP channels, a remarkably functional familiy." Cell 108, 595-598.
Moran M, Xu H, Clapham DE (2004). "TRP ion channels in the nervous system." Current Opinion in Neurobiology, 14:362-369.
Muller J, Davis MJ, Kuo L, Chilian WM (1999). "Changes in coronary endothelial cell Ca2+ concentration during shear stress- and agonist-induced
vasodilation." Am J Physiol 276: H1706-1714.
Muraki K, Shigekawa M, Imaizumi Y (2007). A New Insight into the Function of TRPV2 in Circulatory Organs. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S.
Boca Raton, FL, CRC Press: 389-396.
Nilius B, Droogmans G (2001). "Ion channels and their functional role in vascular endothelium." Physiol Rev 81: 1415-1459.
Nilius B, Droogmans G, Wondergem R (2003). "Transient receptor potential channels in endothelium: solving the calcium entry puzzle?" Endothelium 10: 5-15.
Nilius B, Vriens J, Prenen J, Droogmans G, Voets T (2004). "TRPV4 calcium entry channel: a paradigm for gating diversity." Am J Physiol Cell Physiol 286: C195-205.
Nollert M, Eskin SG, McIntire LV (1990). "Shear stress increases inositol
trisphosphate levels in human endothelial cells." Biochem. Biophys. Res.
Commun., 170, 281-287.
69 O'Neil R, Heller S (2005). "The mechanosensitive nature of TRPV channels."
Pflügers Arch 451: 193-203.
Oancea E, Wolfe JT, Clapham DE (2006). "Functional TRPM7 channels
accumulate at the plasma membrane in response to fluid flow." Circ Res 98: 245-253.
Planells-Cases R, Ferrer-Montiel A (2007). TRP Channel Trafficking. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling
Cascades. W. Liedtke, Heller, S. Boca Raton, FL, CRC Press: 319-330.
Plant T, Strotmann R (2007). TRPV4: A Multifunctional Nonselective Cation Channel with Complex Regulation. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. W. Liedtke, Heller, S.
Boca Raton, FL, CRC Press: 125-140.
Pohl U, Holtz J, Busse R, Bassenge E (1986). "Crucial role of endothelium in the vasodilator response to increased flow in vivo." Hypertension, 8, 37-44.
Reiter B, Kraft R, Günzel D, Zeissig S, Schulzke JD et al (2006). "TRPV4-mediated regulation of epithelial permeability." FASEB J 20: 1802-1812.
Rosa J, Galanakis D, Ganellin CR, Dunn PM, Jenkinson DH (1998). "Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca2+-activated K+ channel." J Med Chem 41: 2-5.
Shen J, Harada N, Kubo N, Liu B, Mizuno A, Suzuki M, Yamashita T (2005).
"Functional expression of transient receptor potential vanilloid 4 in the mouse cochlea." Neuroreport: 17, 6:135-139.
Si H, Heyken WT, Wolfle SE, Tysiac M, Schubert R (2006). "Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel." Circ Res 99: 537-544.
Ständer S, Moormann C, Schumacher M, Buddenkotte J, Artuc M, Shpacovitch V, Brzoska T, Lippert U, Henz B, Luger T, Metze D, Steinhoff M (2004).
"Expression of vanilloid receptor subtype in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures."
Experimental Dermatology:13: 129-139.
Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD (2000).
"OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity." Nat Cell Biol 2: 695-702.
Sun D, Huang A, Smith CJ, Stackpole CJ, Connetta JA, Shesely EG, Koller A, Kaley G (1999). "Enhanced release of prostaglandins contributes to flow-induced arteriolar dilation in eNOS knockout mice." Circ Res 85: 288-293.
Suzuki M, Mizuno A, Kodaira K, Imai M (2003). "Impaired pressure sensation in mice lacking TRPV4." J Biol Chem 278: 22664-22668.
Tabuchi K, Suzuki M, Mizuno A, Hara A (2005). "Hearing impairment in TRPV4 knockout mice." Neurosci Lett 382: 304-308.
Taniguchi J, Tsuruoka S, Mizuno A, Sato J, Fujimura A (2007). "TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct." Am J Physiol Renal Physiol 292: F667-673.
Thorneloe K, Sulpizio A, Lin Z, Figueroa D, Clouse A, McCafferty G,
Chendrimada T, Lashinger E, Gordon E, Evans L, Misajet B, DeMarini D,
70 Nation J, Casillas L, Marquis R, Votta B, Sheardown S, Xu X, Brooks D, Laping N, Westfall T (2008).
"N-((1S)-1-{[4-((2S)-2-{[(2,4-
Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part 1." JPET 326:432-442.
Tian W, Salanova M, Xu H, Lindsley JN, Oyama TT, Anderson S, Bachmann S, Cohen DM (2004). "Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments."
Am J Physiol Renal Physiol 287: F17-24.
Todaka H, Taniguchi J, Satoh J, Mizuno A, Suzuki M (2004). "Warm
temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia." J Biol Chem 279: 35133-35138.
Trebak M, Bird G, McKay R, Putney J (2002). "Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes." The Journal of Biological Chemistry, 277, 24, pp. 21617-21623.
Trebak M, Lemonnier L, Smyth JT, Vazquez G, Putney JWJr (2007).
"Phospholipase C-coupled receptors and activation of TRPC channels."
Handb Exp Pharmacol: 593-614.
Vriens J, Owsianik G, Fisslthaler B, Suzuki M, Janssens A (2005). "Modulation of the Ca2+ permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium." Circ Res 97: 908-915.
Vriens J, Watanabe H, Janssens A, Droogmans G, Voets T, Nilius B (2004).
"Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4." Proc Natl Acad Sci USA 101:
396-401.
Watanabe H, Davis JB, Smart D, Jerman JC, Smith GD (2002). "Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives." J Biol Chem 277: 13569-13577.
Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T (2003). "Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels." Nature 424: 434-438.
Watanabe H, Vriens J, Suh SH, Benham CD, Droogmans G (2002). "Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells." J Biol Chem 277:
47044-47051.
Willette R, Bao W, Nerurkar S, Yue T, Doe CP, Stankus G, Turner GH, Ju H, Thomas H, Fishman CE, Sulpizio A, Behm DJ, Hoffman S, Lin Z, Lozinskaya I, Casillas LN, Lin M, Lee Trout R, Votta BJ, Thorneloe K, Lashinger ESR, Figueroa DJ, Marquis R, Xu X (2008). "Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2."
JPET 326:443-452.
Wissenbach U, Bödding M, Freichel M, Flockerzi V (2000). "Trp12, a novel Trp-related protein from kidney." FEBS Lett. 485, 127-134.
Wissenbach U, Niemeyer BA, Flockerzi V (2004). "TRP channels as potential drug targets." Biol Cell 96: 47-54.
71 Wu L, Gao X, Brown RC, Heller S, O'Neil RG (2007). "Dual role of the TRPV4
channel as a sensor of flow and osmolality in renal epithelial cells." Am J Physiol Renal Physiol, F1699-713.
Wulff H, Miller MJ, Hansel W, Grissmer S, Cahalan MD (2000). "Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant." Proc Natl Acad Sci USA 97: 8151-8156.
Yang R, Lin MJ, MacIntosh L, Sham JSK (2006). "Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle." Am J Physiol Lung Cell Mol Physiol 290: L1267-1276.
Yin J, Hoffmann J, Kaestle SM, Neye N, Wang L, Baeurle J, Liedtke W, Wu S, Kuppe H, Pries AR, Kuebler WM (2007). "Negative-Feedback Loop Attenuates Hydrostatic Lung Edema via a cGMP-Dependent Regulation of Transient Receptor Potential Vanilloid 4." Circ Res. 102: 966-974.
Zhang D, Mendoza SA, Bubolz AH, Mizuno A, Ge ZD, Li R, Warltier DC, Suzuki M, Gutterman DD (2009). "Transient Receptor Potential Vanilloid Type 4 Deficient Mice Exhibit Impaired Endothelium-Dependent Relaxation Induced by Acetylcholine In Vitro and In Vivo." Hypertension 53: 532-538.
Zhao H, Liu Q, Chi BR (2005). "Role of endothelium-derived hyperpolarizing factor in shear stress-induced endothelium-dependent relaxations of rats." Yao Xue Xue Bao 40: 491-495.
72