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Aden DP, Fogel A, Plotkin S, Damjanov I und Knowles BB

Controlled synthesis of HbsAg in a differentiated human liver carcinoma-derived cell line.

Nature 1979, 282, 615-616... 46 Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW und Yuan

JY

Human ICE/Ced-3 protease nomenclature. Cell 1998, 87, 171-... 24 Antonsson B, Montessuit S, Lauper S, Eskes R und Martinou JC

Bax oligomerisation is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria. Biochem J 2000, 345(2), 271-278 ... 30 Baker SJ und Reddy EP

Transducers of life and death

TNF receptor superfamily and associated proteins. Oncogene 1996, 12, 1-9 ... 23 Bantel H, Lugering A, Poremba C et al.

Caspase activation correlates with the degree of inflamatory liver injury in chronic hepatitis C virus infection. Hepatology 2001, 34, 758-767... 106 Bantel H., Lugering A., Heidemann J., Volkmann X., Poremba C., Strassburg C. P., Manns M. P.

und Schulze-Osthoff K.

Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury. Hepatology 2004, 40, 1078-1087 ... 106 Beck J, Bartos H und Nassal M

Experimental conformation of a hepatitis B virus (HBV) ε-like bulge-and -loop structure in avian HBV RNA encapsidation signals. Virology 1997, 227, 500-504... 13 Benchimol S.

p53 - an examination of sibling support in apoptosis control. Cancer Cell 2004, 6, 3-4 ... 34 Berry MN und Friend DS

High yield preparation of isolated rat liver parenchymal cells

a biochemical and fine structural study. J Cell Biol 1969, 43, 506-520... 47 Berry MN, Grivell AR, Grivell MB und Phillips JW

Isolated hepatocytes - past, present and future. Cell Biol Toxicol 1997, 13, 223-233... 47 Blagosklonny M. V.

Cel death beyond apoptosis. Leukemia 2000, 14, 1502-1508 ... 31 Boldin M.P., Mett I.L., Varfolomeev E.E., Chumakov I., Shemer-Avni Y., Camonis J.H. und

Wallach D.

Self-association of the "Death Domains" of the p55 Tumor Necrosis Factor (TNF) receptor and Fas/Apo 1 prompts signaling for TNF and Fas/Apo 1 effects. JBC 1995, 270, 387-391.... 104 Bréchot C

Pathogenesis of hepatitis B virus-related hepatocellular carcinoma

old and new paradigms. Gastroenterology 2004, 127, 556-561... 35 Calabrese F, Pontiso P, Perrenazzo E et al.

Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels. Hepatology 2000, 31, 1153-1159... 106 Cao Y., Hamada T., Matsui T., Date T. und Iwabuchi K.

Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/ASPP2, and inhibits p53-mediated apoptosis. Biochem Biophys Res Commun 2004, 315, 788-795 ... 36 Castedo M., Perfettini J. L., Roumier T., Andreau K., Medema R. und Kroemer G.

Cell death by mitotic catastrophe

a molecular definition. Oncogene 2004, 23, 2825-2837 ... 31 Chen C und Okayama H

High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987, 7, 2745-2752 ... 53 Chen HL, Wu HL, Fon CC, Chen PJ, Lai MY und Chen DS

Long-term culture of hepatocytes from human adults. J. Biomed Sci 1998, 5, 435-440 ... 47 Chen HY, Tang NH, Li XJ, Zhang SJ, Chen ZX und Wang XZ

Transfection and expression of the hepatitis B virus x gene and its effect on apoptosis in HL 7702 cells. W J Gastr. 2004, 10(7), 959-964... 99 Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T und Korsmeyer SJ

Bcl-2, bcl-x(L) sequester BH3 domain-only molecules preventing bax- and bak-mediated mitochondrial apoptosis. Mol Cell 2001, 8, 705-711... 30 Cheng P.L., Chang M.H., Chao C.H. und Lee Y. H.

Hepatitis C viral proteins interact with Smad3 and differentially regulate TGF-beta/Smad3-mediated transcriptional activation. Oncogene 2004, 23, 7821-7838 ... 107 Chirillo P, Pagano S, Natoli G, Puri PL, Burgio VL, Balsano C und Levrero M

The hepatitis B virus X gene induces p53-mediated programmed cell death. Proc Natl Acad Sci USA 1997, 94, 8162-8167 ... 35 Chisari FV and Ferrari C

Hepatitis B virus immunopathogenesis, Annu Rev Immunol 1995... 10 Chisari FV, Ferrari C und Mondelli MU

Hepatitis B virus structure and biology. Microb Pathol 1989, 6(5), 311-325 ... 11 Chung Y. L., Sheu M. L. und Yen S. H.

Hepatitis C virus NS5A as a potential viral Bcl-2 homologue interacts with Bax and inhibits apoptosis in hepatocellular carcinoma. Int J Cancer 2003, 107, 65-73 ... 36 Ciccaglione A. R., Marcantonio C., Tritarelli E., Equestre M., Magurano F., Costantino A.,

Nicoletti L. und Rapicetta M.

The transmembrane domain of hepatitis C virus E1 glycoprotein induces cell death. Virus Res 2004, 104, 1-9 ... 36 Classen, Diehl, Kochsiek (Hrsg.)

Innere Medizin, Verlag Urban und Schwarzenberg 2004...9, 19, 91, 101, 106 Debatin KM und Krammer PH

Death receptors in chemotherapy and cancer. Oncogene 2004, 23(16), 2950-2966... 116 Dhein J, Daniel PT, Trauth BC, Oehm A, Moller P und Krammer PH

Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J Immunol 1992, 149, 3166-3173... 24 Dhein J, Walczak H, Bäumler C, Debatin KM und Krammer PH

Autocrine T-cell suicide mediated by APO-1/Fas/CD95. Nature 1995, 373, 438-441... 21 Drazan KE

Molecular biology of hepatitis C infection. Liver Transpl 2000, 6(4), 396-406... 16 Ehrmann J. Jr., Galuszkova D., Ehrmann J., Krc I., Jezdinska V., Vojtesek B., Murray P.G. und

Kolao Z.

Apoptosis-related proteins, Bcl-2, Bax, Fas, FasL and PCNA in liver biopsies of patients with chronic hepatitis B virus infection. Pathol Oncol Res 2000, 6, 130-135... 104 Eichhorst ST, Müller M, Li-Weber M, Schulze-Bergkamen H, Angel P und Krammer PH

A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma upon treatment with anticancer drugs. Mol Cell Biol 2000, 20, 7826-7837 ... 90 El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW und Vorgelstein B

Definition of a consensus binding site for p53. Nature Genetics 1992, 1, 45-49... 116 el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM et al.

WAF1, a potential mediator of p53 tumor suppression. Cell 1993, 75, 817-825 ... 33 Elmore LW, Hancock AR, Chang SF et al.

Hepatitis B virus X protein and p53 tunor suppressor interactions in the modulation of

apoptosis. Proc Natl Acad Sci USA 1997, 94(26), 14707-14712 ... 35 El-Serag HB und Mason AC

Rising incidence of hepatocellular carcinoma in the United States. N Eng J Med, 340(10), 745-750 ... 14 Enari M, Hug H und Nagata S

Involvement of an ICE-like proteasein Fas-mediated apoptosis. Nature 1995, 375, 78-81... 28 Ferrini JB, Rodrigues E, Dulic V, Pichard-Garcia L, Fabr JM, Blanc P et al.

Expression and DNA-binding activity of C/EBPalpha and C/EBPbeta in human liver and differentiated primary hepatocytes. J Hepatol 2001, 35, 170-177... 47 Fridman JS und Lowe SW

Control of apoptosis by p53. Oncogene 2003, 22(56), 9030-9040 ... 116 Galle PR, Hofmann WJ, Walczak H, Schaller H, Otto G, Stremmel W, Krammer PH und Runkel L

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med 1995, 182, 1223-1230 ... 35, 96 Gervais FG, Xu D, Robertson GS, Vaillancourt JP, Zhu Y, Huang Y, LeBlanc A, Smith D, Rigby

M, Shearman MS, Clarke EE, Zheng H, VanDerPloeg LHT, Ruffolo SC, Thornberry NA, Xanthoudakis S, Zamboni RJ, Roy S und Nicholson DW

Involvement of caspases in proteolytic cleavage of alzheimer's amyloid-b precursor protein and amyloidogenic Ab peptide formation. Cell 1999, 97, 960-963 ... 25 Gesenhues S und Ziesché R

Praxisleitfaden Allgemeinmedizin, Urban und Fischer Verlag, 4. Auflage 2003... 19, 20

Goodrick CL

Lifespan and the inheritance of longevity of inbred mice. J Gerontol 1975, 30, 257-263 ... 44 Gottlob K, Fulco M, Levrero M und Graessmann A

The hepatitis B virus HBx protein inhibits caspase 3 activity. J Biol Chem 1998, 273(50), 33347-33353 ... 35, 99 Graham FL, Smiley J, Russel WC und Nairn R

Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 1977, 36, 59-72 ... 46 Green D

Apoptotic pathways

Paper wraps stone blunts scissors. Cell 2000, 102, 1-4... 29 Gressner O., Schilling T., Lorenz K., Schulze Schleithoff E., Koch A., Schulze-Bergkamen H.,

Candi A.M.L.E., Terrinoni A., Catani M.V., Oren M., Melino G., Krammer P.H., Stremmel W.

und Müller M.

TAp63α induces apoptosis by activating signaling via death receptors and mitochondria.

EMBO J 2005, 24, 2458-2471 ... 34 Greten (Hrsg.)

Innere Medizin, Thieme Verlag 2002, 807-824...9, 19, 91, 101, 106 Griffith TS, Brunner T, Fletcher SM, Green DR und Ferguson TA

Fas-ligand induced apoptosis as a mechanism of immune privilege. Science 1995, 270, 1189 23 Guenetta R.S., Mooibroek M., Wong K., Wong P. and Tenniswood M.

Cathepsin B, a cysteine protease implicated in metastatic progression, is also expressed during regression of the rat prostate and mammary glands. Eur J Biochem 1994, 226, 311-321 .... 31 Guguen-Guillouzo C und Guillouzo A

Modulation of functional activities in cultured rat hepatocytes. Mol Cell Biochem 1983, 54, 35-56 ... 47 Guidotti LG, Matzke B, Schaller H und Chisari FV

High-level hepatitis B virus replication in transgenic mice. J Virol 1995, 69, 6158-6169 ... 54 Hahn JM

Checkliste Innere Medizin, Thieme Verlag, 3. Auflage 2003... 19, 20 Harris CC

Structure and function of the p53 tumor suppressor gene

clues for rational cancer therapeutic strategies. J Nat Canc Inst 1996, 88(20), 1442-1455... 32 He TC, Zhou S, Da Costa LT, Yu J und Vogelstein K

A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 1998, 95, 2509-2514 ... 50, 72 Heermann KH and Gerlich WH

Surface proteins of hepatitis B viruses. In McLachlan (Hrsg.)

Molecular biology of the hepatitis B virus, CRC Press. Boca Raton, Florida, 109-144 ... 11 Hofseth LJ, Hussain SP und Harris CC

p53

25 years after its discovery. Trends Pharmacol Sci 2004, 25(4), 177-181... 116 Hsia CC, Kleiner DE Jr, Axiotis CA, Di Bisceglie A, Nomura AM, Stemmermann GN und Tabor

E

Mutations of p53 gene in hepatocellular carcinoma

roles of hepatitis B virus and aflatoxin contamination in the diet. J Natl Cancer Inst 1992, 84, 1638-1641 ... 100 Hsu IC, Lipsky MM, Cole KE, Su CH und Trump BF

Isolation and culture of hepatocytes from human liver of immediate autopsy. In Vitro Cell Dev Biol 1985, 21, 154-160 ... 47 Huang DC, Cory S und Strasser A

Bcl-2, Bcl-XL and adenovirus protein E1B 19 kD are functionally equivalent in their ability to inhibit cell death. Oncogene 1997, 14, 405-414... 24 Huovila AP, Eder AM und Fuller SD

Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment. J Cell Biol 1992, 118, 1305-1320 ... 13 Itoh N und Nagata S

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J Biol Chem 1993, 268, 10932 ... 23 Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y und

Nagata S

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate

apoptosis. Cell 1991, 66, 233-243... 23 Jäättelä M.

Multiple cell death pathway as regulators of tumor initiation and progression. Oncogene 2004, 23, 2746-2756 ... 31 Jaitovich-Goisman I, Koshy R, Henkler F, Groopman JD und Alaoui-Jamali MA

Downregulation of DNA excision repair by the hepatitis B virus X protein occurs in p53-proficient and p53-deficient cells. Carcinogenesis 1999, 20(3), 479-483... 35 Jarmay K., Karacsony G., Ozsvar Z., Nagy I., Lonovics J. und Schaff Z

Assessment of histological features in chronic hepatitis C. Hepatogastroenterology 2002, 49, 239-243 ... 107 Johnson RA, Ince TA und Scotto KW

Transcriptional repression by p53 through direct binding to a novel DNA element. JBC 2001, 276(29), 27716-27720... 116 Junker-Niepmann M, Bartenschlager R und Schaller H

A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA. EMBO J 1990, 9, 3389-3396 ... 13 Kagiyama N, Takakura A, Koyoma K, Terada E und Sakuria Y

Detection of mouse hepatitis virus antibody by protein A-ELISA in 6 prevalent inbred strains or outbred stocks of mice. Lab Anim 1991, 25, 106-109 ... 44

Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K und Yagita H

Metalloprotease-mediated release of human Fas ligand. J Exp Med 1995, 182, 1777-1783 ... 23 Kim K. H. und Seong B. L.

Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and

enhancement of death-inducing signal. EMBO J 2003, 22, 2104-2116... 35, 99 Kitanaka C. und Kuchino Y.

Caspase-independent programmed cell death with necrotic morphology. Cell Death Differ 1999, 6, 508-515 ... 31 Kluck RM, Bossywetzel E, Green DR und Newmeyer DD

The release of cytochrome c from mitochondria

a primary site for Bcl-2 regulaton of apoptosis. Science 1997, 275, 1132-1136... 27 Knowles BB, Howe CC und Aden DP

Human hepatocellular carcinoma cell lines secrete the major plasma protein and hepatitis B surface antigen. Science 1980, 209, 497-499... 46 Krammer PH

CD95 (APO-1/Fas)-mediated apoptosis

live and let die. Adv Immun 1999, 71, 163-210... 21 Lai MMC und Mason WS

Molecular Biology of Hepatitis Viruses. in

The liver. Verlag Lippincott Williams & Wilkins, Philadelphia 2001, 840-844... 15 Lau JYN, Xie X, Lai MMC und Wu PC

Apoptosis and viral hepatitis. Semin Liver Dis 1998, 18, 169-176 ... 106 Lauer GM und Walker BD

Hepatitis C virus infection. N Engl J Med 2001, 345(1), 41-52 ... 15 Le Prevost C, Virelizier JL und Dupuy JM

Immunopathology of mouse hepatitis virus type III. Clinical and virologic observation of a persistent viral infection. J Immunol 1975, 115, 640-643... 44 Lee JY, Chae DW, Kim SM, Nam ES, Jang MK, Lee JH, Kim HY und Yoo JY

Expression of FasL and perforin/granzyme B mRNA in chronic hepatitis B virus infection. J Vir Hep 2004, 11, 130-135 ... 97 Lee SG und Rho HM

Transcriptional repression of the human p53 gene by hepatitis B viral X protein. Oncogene 2000, 19, 468-471 ... 102, 103 Lee Y. I., Hwang J. M., Im J. H., Lee Y. I., Kim N. S., Kim D. G., Yu D. Y., Moon H. B. und Park

S. K.

Human hepatitis B virus X protein alters mitochondrial function and physiology in human liver cells. JBC 2004, 279, 15460-15471 ... 35 Leithäuser F, Dhein J, Mechtersheimer G, Koretz K, Brüderlein S, Henne C, Schmidt A, Debatin

KM, Krammer PH und Möller P

Constitutive and induced expression of Apo-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 1993, 69, 415 ... 23 Levine AJ

p53, the cellular gatekeeper for growth and division. Cell 1997, 88, 323-331 ... 33 Levrero M, De Laurenzi V, Costanzo A, Gong J, Wang JY und Melino G

The p53/p63/p73 family of transcription factors

overlapping and distinct functions. J Cell Sci 2000, 113(10), 1661-1670 ... 116 Lockshin R.A. und Zakeri Z.

Caspase-independent cell death? Oncogene 2004, 23, 2766-2773 ... 31 Los M, Van de Craen M, Penning LC, Schenk H, Westendorp M, Baeuerle PA, Bröge W,

Krammer PH, Fiers W und Schulze-Osthoff K

Requirement of an ICE/CED-3 protease for Fas/APO-11-mediated apoptosis. Nature 1995, 375, 81-83 ... 28 Mariani SM, Matiba B, Baumler C und Kramer PH

Regulation of cell surface APO-1/Fas (CD95) ligand expression by metalloproteases. Eur J Immunol 1995, 25, 2303-2307... 23 Mathonnet G., Lachance S., Alaoui-Jamali M. und Drobetsky E. A.

Expression of hepatitis B virus X oncoprotein inhibits transcription-coupled nucleotide excision repair in human cells. Mut Res 2004, 554, 305-318 ... 35 Melino G, De Laurenzi V und Vousden KH

p73

Friend or foe in tumorigenesis. Nat Rev Cancer 2002, 2(8), 605-615 ... 116 Melino G., deLaurenzi V. and Vousden K.H.

p73

friend or foe in tumorigenesis. Nat Rev Cancer 2002, 2, 605-615... 34 Melino G., Lu X., Gasco M., Crook T. und Knight R.A.

Functional regulation of p73 and p63

development and cancer. Trends Biochem Sci 2003, 28, 663-670 ... 34 Mills A.A., Zheng B., Wang X.J., Vogel H., Roop D.R. and Bradley A.

p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999, 398, 708-713 ... 34 Minn AJ, Kettlun CS, Liang H, Kelekar A, Vander Heiden MG, Chang BS, Fesik SW, Fill M und

Thompson CB

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms.

EMBO J 1999, 18, 632-643 ... 30 Mittl PR, Di Marco S, Krebs JF, Bai X, Karanewsky DS, Priestle JP, Tomaselli KJ und Grutter

MG

Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone. J Biol Chem 1997, 272, 6539-6547... 24 Miura M, Friedlander RM und Yuan J

Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway.

Proc Natl Acad Sci USA 1995, 92, 8318-8322... 28 Miyashita T und Reed JC

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80, 293-299 ... 58, 104 Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Lieberman DA et al.

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Oncogene 1994, 9, 1799-1805 ... 33 Mochizuki K, Hayashi N, Hiramatsu N, Katayama Y, Kasahara A, Fusamoto H und Kamada T

Fas antigen expression in liver tissues of patients with chronic hepatitis B. J Hepatol 1996, 24, 1-7 ... 102 Moll U.M. und Slade N.

p63 and p73

roles in development and tumor formation. Mol Cancer 2004, 2, 371-386 ... 34 Müller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer

PH und Galle PR

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas)

receptor/ligand system and involves activation of wild-type p53. J Clin Invest 1997, 99, 403-413 ...33, 46, 81, 90, 100 Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedmann SL, Galle PR,

Stremmel W, Oren M und Krammer PH

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs, J Exp Med 1998, 188, 2033-2045...33, 46, 81, 82, 100, 103 Müller M., Schilling T., Sayan A.E., Kairat A., Lorenz K., Schulze-Bergkamen H., Oren M., Koch

A., Stremmel W., Tannapfel A., Melino G. und Krammer P.H.

TAp73/∆Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma. Cell Death Differ 2005, 12, 1564-1577 ... 34 Murakami S

Hepatitis B virus X protein

Structure, function and biology. Intervirology 1999, 42, 81-99... 103, 107 Nassal M und Schaller H

Hepatitis B virus replication. Trends Microbiol 1993 ... 11 Nicoletti I, Migliorati G, Paggliacci MC, Grignani F und Riccardi C

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991, 139(2), 271-279... 64, 78 Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J und

Trauth BC

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J Biol Chem 1992, 267, 10709-10715... 23

Ona VO, Li M, Vonsattel JPG, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JHJ und Friedlander RM

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease.

Nature 1999, 399, 263-267... 25 Osada M., Ohba M., Kawahara C., Ishioka C., Kanamaru R., Katoh I., Ikawa Y., Nimura Y.,

Nakagawara A., Obinata M. und Ikawa S.

Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 1998, 4, 839-843 ... 34 Patzer EJ, Nakamura GR, Simonsen CC, Levinson AD und Brands R

Intracellular assembly and packaging of hepatitis B surface antigen particles occur in the endoplasmatic reticulum. J Virol 1986, 58, 884-892 ... 13 Pellegrini G., Dellambra E., Golisano O., Martinelli E., Fantozzi I., Bondanza S., Ponzin D.,

McKeon F. and deLuca M.

p63 identifies keratinocyte stem cells. PNAS 2001, 98, 3156-3161 ... 34 Peter ME und Krammer PH

The CD95 (APO-1/Fas) DISC and beyond. Cell Death Diff 2003, 10(1), 26-35 ... 24 Peter ME, Scaffidi C, Medema JP, Kischkel F und Krammer PH

The death receptors. In Apoptosis

Biology, mechanisms and role in disease, Springer Verlag Heidelberg 1998, 25-63 21, 23, 28

Petit PX, Lecoeur H, Zorn E, Dauguet C, Mignotte B und Gougeon ML

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 1995, 130, 157-167... 26 Prikhod’ko E. A., Prokhod'ko G. G., Siegel R. M., Thompson P., Major M. E. und Cohen J. I.

The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities. Virology 2004, 329, 53-67 ... 36 Realdon S., Gerotto M., Dal Pero F., Marin O., Granato A., Basso G., Muraca M. und Alberti A.

Proapoptotic effect of hepatitis C virus core protein in transiently transfected cells is enhanced by nuclear localization and is dependent on PKR activation. J Hepatology 2004, 40, 77-85 36 Reese JA und Byard JL

Isolation and culture of adult hepatocytes from liver biopsies. In Vitro 1981, 17, 935-940... 47 Roninson I. B., Broude E. V. und Chang B. D.

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Update 2001, 4, 303-313... 31 Rothstein TL, Wang JK, Panka DJ, Foote LC, Wang ZU, Stanger B, Cui H, Ju ST und

Marshak-Rothstein A

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 1995, 374, 163-165 ... 21 Rotonda J, Nicholson DW, Fazil KM, Gallant M, Gareau Y, Labelle M, Peterson EP, Rasper DM,

Ruel R, Vaillancourt JP, Thornberry NA und Becker JW

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis. Nat Struct Biol 1996, 3, 619-625 ... 24 Sartorius U, Schmitz I und Krammer PH

Molecular mechanisms of death-receptor-mediated apoptosis. ChemBioChem 2001, 2(1), 20-29 ... 116 Schulze-Bergkamen H und Krammer PH

Apoptosis in cancer – implications for therapy. Semin Oncol 2004, 31(1), 90-119 ... 116 Schulze-Bergkamen H., Brenner D., Krueger A., Suess D., Fas S. C., Frey C. R., Dax A., Zink D.,

Büchler P., Müller M. und Krammer P. H.

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. Hepatology 2004, 39/3, 645-654 ... 70 Schulze-Bergkamen H., Untergasser A., Dax A., Vogel H., Büchler P., Klar E., Lehnert T., Friess

H., Büchler M.W., Kirschfink M., Stremmel W., Krammer P. H., Müller M. und Protzer U.

Primary human hepatocytes - a valuable tool for investigation of apoptosis and hepatitis B virus infection. J. Hepatol. 2003, 38/6, 736-744 ... 70 Seglen PO

Preparation of isolated rat liver cells. Methods Cell Biol 1976, 13, 29-83 ... 47 Shih W. L., Kuo M. L., Chuang S. E., Cheng A. L. und Doong S. L.

Hepatitis B virus X protein activates a survival signaling by linking SRC to

phosphatidylinositol 3-kinase. JBC 2003, 278, 31807-31813... 35, 99 Smith CA, Farrah T und Goodwin RG

The TNF receptor superfamily of cellular and viral proteins

activation, costimulation, and death. Cell 1994, 76, 959-962 ... 23 Sprinzl MF, Oberwinkler H, Schaller H und Protzer U

Transfer of hepatitis B virus genomes by adenovirus vectors into cultured cells and mice crossing the species barrier. J Virol 2001, 75, 5108-5118 ... 44, 96 Srinivas D, Mani H, Crumpler C und Van Thiel DH

Daily interferon therapy for chronic hepatitis C

a report of the community practice experience. Hepagastroenterology 2002, 49, 1053-1957 ... 15 Storer JB

Longevity and gross pathology at death in 22 inbred strains of mice. J Gerontol 1966, 21, 404-409 ... 44 Strand S, Hofmann WJ, Hug H, Müller M, Otto G, Strand D, Mariani S, Stremmel W, Krammer

PH und Galle PR

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells- a

mechanism of immune evasion? Nature Med 1996, 2, 1361-1366 ... 35, 96 Street A., Macdonald A., Crowder K. und Harris M.

The hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade. JBC 2004, 279, 12232-12241... 36 Su H und Yee JK

Regulation of hepatitis B virus gene expression by its two enhancers. Proc Nat Acad Sci USA 1992, 89, 2708-2712 ... 13 Suda T, Takahashi T, Golstein P und Nagata S

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993, 75, 1169-1178 ... 23 Suriawinata A und Xu R

An update on the molecular genetics of hepatocellular carcinoma. Semin Liver Dis 2004, 24(1), 77-88 ... 116 Suzuki R, Suzuki T, Ishii K, Matsuura Y und Miyamura T

Processing and functions of hepatitis C virus proteins. Intervirology 1999, 42, 145-152 ... 17 Takahashi T, Tanaka M, Inazawa J, Abe T, Suda T und Nagata S

Human Fas ligand

gene structure, chromosomal location and species specificity. Int Immunol 1994, 6, 1567-1574... 23 Tanaka M, Suda T, Takahashi T und Nagata S

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

EMBO J 1995, 14, 1129-1135 ... 23 Tanaka Y, Kanai F, Kawakami T, Tateishi K, Ijichi H, Kawabe T, Arakawa Y, Kawakami T,

Nishimura T, Shirakata Y, Koike K und Omata M

Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx mediated apoptosis. Biochem Biophys Res Com 2004, 318(2), 461-469 ... 111 Tartaglia LA, Ayres TM, Wong GH und Goeddel DV

A novel domain within the 55 kd TNF receptor signals cell death. Cell 1993, 74, 845-853 ... 23 Terradillos O, Pollicino T, Lecoeur H, Tripodi M, Gougeon ML, Tiollais P et al.

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro.

Oncogene 1998, 17(16), 2115-2123... 35 Tewari M, Quan LT, O´Bourke K, Desnoyers S, Zeug Z, Beidler DR, Poirier GG, Salvesen GS

und Dixit VM Yama/CPP32 beta

a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995, 81, 801-809 ... 28 Tiollas P, Charnay P und Vyas GN

Biology of hepatitis B virus. Science 1981, 213(4506), 406-411 ... 11 Trauth BC, Klas C, Peters AM, Matzku S, Moller P, Falk W, Debatin KM und Krammer PH

Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989, 245, 301-305 ... 23 Tsamandas AC, Thomopoulos K, Zolota V, Kourelis T, Karatzas T, Ravazoula P, Tepetes K,

Petsas T, Karavias D, Karatza C, Bonikos DS und Gogos C

Potential role of bcl-2 and bax mRNA and protein expression in chronic hepatitis type B and C a clinicopathologic study. Mod Path 2003, 16(12), 1273-1288 ... 103 Tsujimoto Y