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• Manuela Denz, Gerrit Brehm, Clément Y. J. Hémonnot, Heidi Spears, Andrew Wittmeier, Chiara Cassini, Oliva Saldanha, Eleonora Perego, Ana Diaz, Manfred Burghammer and Sarah Köster. Cyclic olefin copolymer as an X-ray compatible material for microfluidic devices.Lab Chip,18, 171-178 (2018). DOI: 10.1039/C7LC00824D

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Acknowledgement

Without the help of many, I would not have been able to make this work as it is. I would like to thank all the contributors, collaborators and friends.

First of all, I would like to thankProf. Sarah Köster, who gave me the opportunity to work on this project in her group and present it at several conferences. Thanks for the fruitful discus-sions and all the support during my PhD time. I thank Prof. Thomas Burgfor being part of my Thesis Advisory Committee and for being the second reviewer of my thesis. For all the help-ful suggestions and comments regarding my project I am very thankhelp-ful. Furthermore, I would like to thank Prof. Ralf Ficnerfor being the third member of my Thesis Advisory Committee and a member of my examination board. Thank you for all the interesting discussions during the meetings. I would like to thankProf. Tim Salditt,Prof. Andreas JanshoffandProf. Helmut Grubmüllerfor being part of my examination board

Many thanks toProf. Harald HerrmannandDr. Norbert Mückefor all the useful discussions during the IF meetings and also for providing the vimentin plasmids. A huge thanks to the su-per support, the long discussions and help at the beamlines fromDr. Ana Diaz(cSAXS, PSI) and Dr. Manfred Burghammer(ID13, ESRF). For the kind introduction to the AFM, I would like to thank the wholegroup of Andreas Janshoff.

A big thanks toManuel Marschall. Not only for being the friend he is, but also for his help on the model-implementation for the vimentin fits and the improvements of the code.

My deepest gratitude to everybody from the IRP, who made the time in Göttingen a mem-orizable time. Thank you all for the great discussions. Furthermore, I would like to thanks Christine Wilke-Feist,Eva Hetzel,Kerstin Pluschke,Sabine BalderandMichaela Ständerfor the absolute wonderful job you did when it came to extending contracts, sick leaves, Dien-streiseanträgen or Reisekostenabrechnungen. ToJochen Herbst,Peter Luley,Susanne Hengst, Ulrike Rölleke,Kamila SabaghandJan Goemanmy gratitude for all their help regarding vac-uum pumps and chillers, clean-room assistance, noise cancelling issues, labstuff or IT prob-lems.

A great thanks to all the members of the group.

I furthermore want thankSusanne Bauch, a very joyful and always helpful person. She did not 179

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only purify the vimentin which was used in this thesis and help me in the lab, but she also recom-mended a lot of ’must have been to’ sights in Göttingen and the surrounding. I’m very grateful that during the 4 long years I always hadEleonora Peregoat my side through this roller-coaster ride called PhD. Many thanks toGerrit Brehm, who always had an open ear to all concerns I had.

Without his work as a master student on the COC devices and the discussions, the microfluidics project would not have come that far. I would like to give my special thanks toJulia Kraxner, a wonderful person who brightened up my last three years. Thanks for all the helpful discussions about vimentin during our chocolate breaks. Special thanks toAnna Zelená, who was always able to make me laugh. For the help with Illustrator I am very thankful. Special thanks toChiara Cassini, who was not only the best beamtime partner I had but who always had the right words and hugs to cheer me up. ToAnna Schepersthe best motivator, my deepest gratitude. She made me see the glitter and the Strassteinchen in my work. Thank you for all the helpful discussions.

Many thanks to Johanna Forsting, who always had an open ear for me. She showed me the handling of vimentin and I am thankful for all the profitable discussions about my project. A special thanks toJana Hanke for the discussions and the 3 o’clock tea times. Thanks to Clé-ment HémonnotandOliva Saldanhafor helping me getting started with my project. For the kind introduction to IFs and X-rays. Thanks to Clément for helping me getting started with Mat-lab and debugging my first codes. My gratitude toMartha Brennichfor helping me understand the code for the micelle model better. I would furthermore like to thankLotta Lorenz,Andrew Wittmeier,Sophie-Charlotte August,Jan-Philipp Burchert,Heidi SomselandAnna Blobfor all your help and beneficial discussions. I would like to thank, Julia, Chiara, Anna S., Anna Z., Eleonora, Heidi, Johanna, Jana, Michael and Janine for proof reading parts of my thesis. Thanks to Gerrit, Chiara, Andrew, Eleonora and Oliva for the help during the beamtimes.

Meinen Eltern, Renateund Werner, danke ich für die vielen Jahre der Unterstützung. Ohne ihre Hilfe wäre ich nie so weit gekommen. Auch einen besonderen Dank für die vielen Diskus-sionen und Anregungen zu meiner Arbeit. Meinem Bruder Michael und seiner Frau Janine, danke ich für die Diskussionen und die Unterstützung, besonders für die last-minute Hilfe mit Latex. Meinem Partner Christoph danke ich für alles was er mit mir in den letzten 4 Jahren durchgemacht hat. Dass er die Geduld mitgebracht hat, auch an einem Wochenende anstelle eines schönen Ausflugs mit mir in die Uni gekommen ist, damit ich meine Experimente machen konnte. Meinen Freunden danke ich besonders für die Unterstützung jeglicher Art, sowie die Nachsicht, wenn ich mal wieder einen Geburtstag verpasst habe.