Part II: Establishment of a retroviral mediated gene
9. Curriculum vitae
Family Name Ratzinger
First Name Sabine
Birth Date June 25, 1978 Nationality German Marital Status Single
Educational Background
2004- Dr.rer.nat.; Pharmacology and Toxicology, University of Regensburg, Germany
1998-2003 Diploma in Biotechnology at the University of Applied Science in Weihenstephan / Freising
Diploma Thesis:
“Investigations on the growth and stimulation conditions of cells as a preparation for the establishment of an endothelial cell bioreactor for experimental sepsis”
Centre for Biomedical engineering, Danube-University Krems, Austria
1994-1998 Higher secondary school; Gymnasium Untergriesbach 1990-1994 Secondary school; Johann-Riederer-Realschule
Hauzenberg
1984-1990 Primary school; Grund- und Hauptschule Untergriesbach
Work Experience
07/2007- Research Associate and Head of the Laboratory; work group “Tissue engineering”, Department of Otorhinolaryngology, University Hospital of Regensburg,
Curriculum vitae
01/2004-06/2007 Doctoral research at the Department of Pharmacology and Toxicology; University of Regensburg, Germany, lead by Prof. Dr. Roland Seifert under the direct supervision of PD Dr. Susanne Grässel, Department of Orthopaedic Surgery, University Hospital Regensburg, Germany
08/2003-11/2003 Technical assistant in R&D department of Applied Science at Roche Diagnostics, Penzberg, Germany
09/2002-06/2003 Diploma Thesis at the Centre for Biomedical engineering, Danube-University Krems, Austria
08/2001-12/2001 Internship at the Centre Centre for Biomedical engineering, Danube-University Krems, Austria
03/2000-07/2000 Internship Milan GmbH & Co KG, Institute for Analytical microbiology and quality control in Passau, Germany
Academic Awards and Honours
July 2008 GlaxoSmithKline travel fellowship July 2007 GlaxoSmithKline travel fellowship
July 2006 Travel fellowship from “Friends of the University of Regensburg”
GlaxoSmithKline travel fellowship
March 2006 Poster prize at the Annual Meeting of the German Connective Tissue Society, Tübingen, Germany,
“Collagen XVI in Crohn’s disease: TGFß-induced expression in intestinal myofibroblasts and cell adhesion properties”
Grants
2009 Grant from Deutsche Krebshilfe “Role of collagen XVI in the oral squamous cell carcinoma” in collaboration with the Department of Maxillofacial surgery and the Department of Orthopaedic surgery
2007 Scholarship of the Max-Buchner-Forschungsstiftung;
#2734: „In vitro gene silencing of collagens in neuronal cells and glia cells”
Publications
Ratzinger S, Eble J A, Pasoldt A, Opolka A, Rogler G, Grifka J, Grässel S
Collagen XVI induces formation of focal contacts on intestinal myofibroblasts isolated from the normal and inflamed intestinal tract.
Matrix Biology, in press
Grässel S, Ratzinger S.
COL161A (collagen, type XVI, alpha1). Atlas Genet Cytogenet Oncol Haematol.
September 2009
URL: http://AtlasGeneticsOncology.org/Genes/COL16A1ID44542ch1p35.html
Appel B, Baumer J, Eyrich D, Sarhan H, Toso S, Englert C, Skodaceck D, Ratzinger S, Grässel S, Göpferich A, Blunk T.
Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.
Osteoarthritis Cartilage, 2009 May 18 (Epub)
Senner V, Ratzinger S, Mertsch S, Grässel S, Paulus W
Collagen XVI expression is upregulated in glioblastomas and promotes tumor cell adhesion.
FEBS Lett. 2008 Oct 15;582(23-24):3293-300. Epub 2008 Sep 17.
Hubert T, Grimal S, Ratzinger S, Mechaly I, Grassel S, Fichard-Carroll A.
Collagen XVI is a neural component of the developing and regenerating dorsal root ganglia extracellular matrix.
Matrix Biol. 2007 Apr:26(3):206-10. Epub 2006 Nov 6
Curriculum vitae
Opolka A, Ratzinger S, Schubert T, Spiegel HU, Grifka J, Bruckner P, Probst A, Grässel S.
Collagen IX is indispensable for timely maturation of cartilage during fracture repair in mice.
Matrix Biol. 2007 Mar;26(2):85-95. Epub 2006 Oct 3
Abstracts presented at conferences Posters
“Establishement of an in vitro larynx model for vocal fold augmentation”
Annual Meeting of the German Society of Otorhinolaryngology and Head and Neck Surgery, Rostock, Germany, May 20-24th 2009
“Collagen XVI – a new marker in oral squamous cell carcinoma?”
Annual Meeting of the German Society of Otorhinolaryngology and Head and Neck Surgery, Rostock, Germany, May 20-24th 2009
“Collagen XVI induces number and length of focal contacts formed by intestinal myofibroblasts isolated from the normal and inflamed intestinal tract”
Annual Meeting of the German Connective Tissue Society, Reims, France, June 3-15th 2009
“Intestinal myofibroblasts exhibit altered proliferation and adhesion properties during inflammatory progression in Crohn’s disease”
Annual Meeting of the German Connective Tissue Society, Freiburg, Germany, April 3-5th 2008
XXIst FECTS meeting, Marseille, France, July 9-13th 2008
“Functional analysis of retroviral mediated knockdown of collagen XVI in NIH3T3 cells”
Annual Meeting of the German Connective Tissue Society, Freiburg, Germany, April 3-5th 2008
XXIst FECTS meeting, Marseille, France, July 9-13th 2008
“Collagen XVI in Crohn’s Disease”
Collagen Gordon Research Conference in New London/USA, July 22nd-27th 2007
“Autologous platelet-rich plasma (PRP) for cartilage tissue engineering“
Annual Meeting of the German Connective Tissue Society, Münster, Germany, March 9-10th 2007
“Collagen XVI in Crohn’s disease: adhesion properties of intestinal myofibroblasts”
Annual Meeting of the German Connective Tissue Society, Münster, Germany, March 9-10th 2007
“TGFß-3 induced expression of collagen XVI and cell adhesion properties of intestinal myofibroblasts under physiological and pathological conditions”
XXth FECTS and ISMB meeting, Oulu, Finland, July 1-5, 2006
“Collagen XVI in Crohn’s disease: TGFß-induced expression in intestinal myofibroblasts and cell adhesion properties”
Annual Meeting of the German Connective Tissue Society, Tübingen, March 9-11th 2006
“Expression and allocation of collagen XVI in inflammatory bowel diseases”
First Joint Meeting of the French and German Connective Tissue Societies Cologne, March 10-12th 2005
Oral presentations
“Collagen XVI – a new marker in oral squamous cell carcinoma?”
Annual Meeting of the German Society of Otorhinolaryngology and Head and Neck Surgery, Rostock, Germany, May 20-24th 2009
“Intestinal myofibroblasts exhibit altered proliferation and adhesion properties during
Curriculum vitae
Annual Meeting of the German Connective Tissue Society, Freiburg, Germany, April 3-5th 2008
“Intestinal myofibroblasts exhibit altered proliferation and adhesion properties during inflammatory progression in Crohn’s disease”
XXIst FECTS meeting, Marseille, France, July 9-13th 2008
“Collagen XVI – of mice and men”
Invited lecture, SFB 492 Extrazelluläre Matrix: Biogenese, Assemblierung und zelluläre Wechselwirkungen, Institut für Physiol. Chemie u. Pathobiochemie, Münster, November 20th 2006