From the present study it can be concluded that there is an evident difference in the success rate of the two mentioned infection types as the trickle-infected group showed a greater impact based on the changes in the intestinal nutrient transport. The most significant findings related to the Ussing chamber technique were shown in the trickle-infected groups. Subsequently, it was simultaneously confirmed that the parasite A. suum does indeed alter the nutrient transport significantly.
Nevertheless, the exact mechanism used by the parasite remains unknown, since the examinations were restricted to the cellular level, as the initial assumption was that the induced changes were only found in the affected tissue at cellular level. However, the investigated cellular parameters based on both mRNA and protein expression level in this experiment were not capable of delivering a sufficient explanation for the significant changes demonstrated in Ussing chamber experiments. Finally, this study strengthens the presumption that the developmental stages of the parasite play a major role in the parasite-host interaction and therefore in the modulation of intestinal transport physiology. The reason for this is that mainly the groups at 49 dpi showed significant findings in the functional characterisation of intestinal nutrient transport.
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