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BCG Bacille Calmette Guerin CD cluster of differentiation

EcN Escherichia coli Nissle 1917 E.coli Escherichia coli

FGF2 fibroblast growth factor 2

g gram

Gfp green fluorescent protein

h hour

HER2 human epidermal growth factor 2

MOI multiplicity of infection

Appendix 102 MRI magnetic resonance imaging

NET neutrophil extracellular trap OD optical density

PAMP pathogen associated pattern PAS Periodic Acid Schiff PBS phosphate buffered saline PCR polymerase chain reaction PDGF platelet-derived growth

REM raster electron microscopy RNA ribonucleic acid

ROS reactive oxygen species RT-PCR reverse transcriptase

polymerase chain reaction

SCV Salmonella containing vacuole

SDM standard deviation of the mean

TGFβ transforming growth factorβ TLR toll-like receptor

TNF tumor necrosis factor TRAIL TNF-related

apoptosis-inducing ligand

TTSS type three secretion system

v volume

VEGF vascular endothelial growth factor

WT wildtype

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Appendix 119

3 Own publications

H. Loessner, S. Leschne, A. Endmann, K. Westphal, K. Wolf, K. Kochruebe, T. Miloud, J. Altenbuchner, S. Weiss.

Drug-inducible remote control of gene expression by probiotic Escherichia coli Nissle 1917 in intestine, tumor and gall bladder of mice

Microbes and Infection (2009). 11 (14-15):1097-1105 K. Crull, D. Bumann, S. Weiss.

Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium

FEMS Immunology & Medical Microbiology (accepted)

K. Crull, M. Rohde, K. Westphal, H. Loessner, K. Wolf, A. Felipe-López, M. Hensel, S.

Weiss.

Biofilm formation by Salmonella enterica serovar Typhimurium colonizing solid tumors Cellular Microbiology (in revision)

K. Crull, S. Weiss.

Antibiotic control of tumor colonizing Salmonella enterica serovar Typhimurium Experimental Biology and Medicine (submitted)

Appendix 120

4 Curriculum vitae

Katja Crull

Date of birth 03/28/1983

Bolkenhainstraße 1e

Maiden name

Kochrübe 38124 Braunschweig

Place of birth

Lauchhammer Katja.Crull@gmx.de

Family status

married

0176 / 23944080

Degree

Dipl.-Biochemist

0176 / 23944080

Degree

Dipl.-Biochemist