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Supplementary Materials Supplementary Table1.

Primary tumor type   Group for number of lesions

χ2 P value Few Medium Extensive

Lung cancer

Sensitivity 57.41 56.89 88.14 63.73 <0.001 Specificity 89.48 83.19 66.96 23.37 <0.001 Accuracy 80.34 73.48 82.54 10.12 0.006

PPV 68.92 66.58 87.90 31.32 <0.001

NPV 84.06 76.48 66.41 12.51 0.002

       

Prostate cancer

Sensitivity 58.13 68.94 89.43 49.42 <0.001 Specificity 90.94 85.93 57.59 54.40 <0.001 Accuracy 84.10 79.83 82.43 1.26 0.532

PPV 63.65 73.66 87.75 26.74 <0.001

NPV 89.05 83.56 62.03 33.55 <0.001

         

Breast cancer

Sensitivity 60.58 68.05 90.41 40.19 <0.001 Specificity 88.03 86.56 63.93 30.01 <0.001 Accuracy 81.57 80.99 82.78 0.35 0.838

PPV 61.68 69.06 85.05 22.00 <0.001

NPV 88.02 86.39 77.72 7.44 0.024

Chi-square test was performed to compare the performance of AI model among different groups of number of lesions. Few lesions group: 1-3 lesions per image; Medium lesions group: 4-6 lesions per image; Extensive lesions group: >6 lesions per image.

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