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BASIC MODEL OF HEALTH CARE SYSTEMS

Wladyslaw Olshansky

June 1976 WP-76-20

Working Papers are internal publications intended for circulation within the Institute only. Opinions or views contained herein are solely those of the author.

2361

I

Laxenburg International Institute for Applied Systems Ana lysis

Austria

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(3)

Basic Model of Health Care System

The philosophy of health care system modelling is described in [1,2,3] and elsewhere.

The first version of a mathematical model of health care system at IIASA's Bio-Medical Project was worked out by

Dr. A. Klementiev. It consisted of a population block and ele- ments for patient treatment and population screening.

One of the goals of this model was to examine the possibility of redistributing health care resources between treatment and

screening.

The resources of health care system--personnel, equipment, etc.--were generalized and represented by "the total number of doctors in practice".

The model was constructed in somewhat general terms and lacked the elaboration of its "fine structure" to become an operating model. This work is a natural continuation of the work on modelling commenced in [3] and [4].

Before elaborating an operating model i t is necessary to develop a basic model that should later grow upon itself the needed details to become an operating model. The first step in this direction was the working out of the model's demographic subsystem which would represent population aging dynamics. This subsystem is described in [4].

The structure of the basic model is shown in Figure 1:

1. Population prevalence dynamics.

2. Populatio~ aging dynamics.

3. Population aging update as interface between (1) and (2).

4. Treatment section.

5. Screening section.

6. Request for admission into health care system.

In this model the following categorization of diseases is accepted. It is presumed that there are three kinds of di.seases [3]:

(4)

1. Diseases of the degenerative t~ have distinctly iden- tified phases and lead to gradual deterioration and death. Ex- amples of this type of disease are cancer, hypertension, TBC, syphilis and alcoholism. We consider three phases of such diseases: phases A, Band C. Phase C may lead to disease- specific death.

2. Acute diseases--accidents, appendicitis, etc.

3. "Non-diseases" that can be eradicated by vaccination-- small-pox, polio, diptheritis, etc.

Prevalence subsystem

Aging update

Population aging routine

Screening Treatment

Management

Figure 1. The Schematic of the Basic Model of the Health Care System

The model at its present stage is being elaborated for a certain disease of Type 1.

Description of Prevalence Dynamics

The population is divided into three categories: healthy people (HP), latent sick (LS) and registered sick (RS). Each category of sickness is divided into three groups with regard

to phase of the disease.

The HP may become latent sick in Phase A with a definite morbidity rate. The LS cannot spontaneously recover. They have either to be admitted for treatment or to deteriorate until death occurs.

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-3-

The RS receive treatment. Phase A corresponds to outpatients, Phase B to inpatients, and Phase C to invalids with irreversible disabilities.

Phase A RS may recover and become HP while Phase B RS can- not immediately recover but may undergo remission and become Phase A RS. Phase C RS deteriorate until death.

Disease-specific death rate in Phase C LS is supposed to be greater than that in Phase C RS, and both - greater than the non-specific death rate.

The HP and LS are the subjects of medical screening to identify sick persons. There is also a natural demand for treatment from those LS who become aware of their disease.

The sick detected by screening plus people who have become aware of their illness by themselves form the treatment demand rate for given phases of the disease.

This pattern of prevalence dynamics seenlS to be good as a first approximation. It may be subsequently refined in further development of the operating model.

Accumulation and flow patterns for different categories of the population can be described by ordinary differential equations which can be easily entered into a computer.

Health Care Activities

Health care resources are represented by the number of physicians.

Health care resources (doctors) should be redistributed according to the existing RS distribution profile for different phases of the disease. This redistribution may be controlled by HCS managers and usually occurs after a certain delay.

The number of sick (PCTD) that doctors serving different phases of the disease can treat is determined by standard work- loads (SWL) set either by the authorities or by other means.

If the number of patients that can be treated by doctors (PCTD) is greater than the number of RS in a given phase of a disease, the difference between these two figures can be admitted to health care system from the LS forming treatment demand rate.

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People admitted to health care determine the real admission rate (REAR). This may be equal to zero if there are less PCTD than RS for a given phase of a disease. In this case the doctors

(i.e. health care resources) are overloaded, and the health care system is able to function due to its inherent resilience.

As stated above, the treatment demand rate is composed of three components: sick detected by screening carried out by doctors, screening carried out by automated equipment, and natural treatment demand.

The natural treatment demand is a function of sanitary education, which is an important aspect of any prophylaxis measures.

Automated screening is more efficient as well as more ex- pensive than screening done by physicians.

To provide for better detection of LS, health care managers should increase investments in automated screening equipment and select the best possible proportion between time doctors spend in screening and that they spend in treatment.

If this proportion is selected incorrectly (for example, if not enough resources are given to screening programs) then all the LS will very quickly pass down to Phase C illness which is an incurable, high death rate state.

If at the other extreme all resources were to go into de- tection, then the detected sick would stay in line for admission-- admission which would never occur. In this case the RS would

not be treated and would never recover.

One of the main reasons for playing games with this model is to determine the golden mean for this kind of situation. The optimal solution here may well be some kind of impulse regime for screening.

Aging Update

All that was said above about dynamics still disregards population aging. The described pattern corresponds to a cer- tain age stratum. The real problem now is how to introduce up- dates for aging.

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-5-

It was decided to run in parallel prevalence dynamics equa- tions and the population aging routine, the latter described in

[4], both subsystems of the model being divided into equivalent sex-age strata and the prevalence subsystem strata being periodi- cally fed with updates from the aging routine structure.

Due to the fact that the sick people with a given disease are usually just a small fraction of the total population and due to the conservative nature of changes in sex-age structure, the aging routine is run less frequently, say, in time increments equal to one year.

The time increments in the prevalence subsystem are set at 0.2 year because of the need to trace out transient effects affected by health care policies.

Thus the basic model operates in the following mode:

- one run of the aging routine is followed by five runs of the prevalence equations--one year passes; then one more run of the aging routine and five runs of the prevalence equations-- one more year passes; and so forth.

Each year any given sex-age stratum in the aging routine loses some people due to aging and their transfer into another stratum, and gains some people from a "previous stratum". The difference between the numbers of these people for a given stratum constitutes a yearly aging update for the stratum.

In more technical terms, these updates are recalculated by special subroutines and added to those people contained in each stratum of each phase of the disease in each step of integration of the prevalence equations.

A yearly "immigration" for a specific phase of a given stratum is equal to the fraction of people in this phase of a

"previous stratum" times the portion (one-fifth) of yearly

"immigration into this stratum of the aging routine. A yearly

"emigration" for a phase of the stratum is equal to the fraction of people in this phase of this stratum times the same portion

(one-fifth) of yearly "emigration" from the considered stratum of the aging routine. The stratum update is the difference between these "immigration" and "emigration" figures.

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Such a simple interpolation taking equal portions o£ an aging "migration" in updates may be erroneous. Work with the basic model will clarify this matter.

Conclusions

A FORTRAN program for this basic model has been written and debugged. The problem now is to compile an array of test data.

The first runs with primitive test data are shown in Appendix 3.

After finishing the implementation of inner feedbacks, the time will come to try various decision-makins options.

The flow chart of the basic model in terms of system dynamics is shown in Figure 2. The variables and equations

are presented in Appendices 1 and 2.

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I -...) I TREATMENT

-:e

(RAGE(B»

(RAGE(A»

(HAGE) MR ~--

/---=

/ / / / / SCREENING

~<J«'

~~~

(.

~ ~+,~Q I / /;

I q<:-«)//-

J.

~///",.-I //./I ///./I.

NDRD~

-_OS

t- -- ,- \ ~ ... -r-- r..---~-~-~4--:ALS~C;]R '!.. / e-- -~

OSPR/

~, \ ~ \ \ '? \

ADMITTANCE

L_/ _

\I\-f \I\/I \I\II \'--...

~ ~_~O~ -i-- ---t-f---

\\----1--...1TFRACI/ ...TFR~"/

..J /

---"..."I"_I---

~

"I/_

~---

...

"

/

- - --- --- ---'-'0--...:::---- ---- --

MANAGEMENT Figure2

(10)

Acknowledgements

This work was discussed in detail with Alexandre Klementiev.

Peter Fleissner happened to squash a pair of bugs in the program.

I am also thankful to James Curry, William Webb and Mark Pearson, who helped me saddle the PDP.

I have also to acknowledge my thanks to GUnther Fischer, who issued a fine lineprinter plotting routine [S], which is very simple to be employed by any user.

All comments are welcome and should be directed to the IIASA Bio-Medical Group.

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[2]

[3]

[4 ]

[5 ]

-9-

REFERENCES

Systems Aspects of Health Planning, Bailey, N.T.J., and M. Thompson, eds., No~th Holland/American Elsevier, Amsterdam, 1975.

Kiselev, A. A Systems Approach to Health Care, RM-75-31, International Institute for Applied Systems Analysis, Laxenburg, Austria, 1975.

Venediktov, D., et al. Health Care: A Systems Approach, CP-76- ,International Institute for Applied Systems Analysis, Laxenburg, Austria, 1976, forthcoming.

Klementiev, A.A. A Computer Method for_projecting a

Population's Sex-Age Structure, RM-76-36, International Institute for Applied Systems Analysis, Laxenburg,

Austria, 1976.

Fischer, G. Multilevel Computer Model of World Development System - Part II, Internal Paper, International

Institute for Applied Systems Analysis, Laxenburg, Aus tr ia , 1 975 .

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Appendix 1

Prevalence Sector Variables AAR(1)

BAR (I) DR(1) HAGEt(1) HPt(1) LAAR(1)

- aggravation rate from phase A - aggravat~on rate from phase B - death rate

healthy persons' aging rate - healthy persons

- aggravation rate from phase A for latent side LAGEt(1,J) - latent sick aging rate

LAT(J) - latent sick in phase J LATS

LBAR(1) LSt(1,J) LSDR(J) MR{1)

- all latent sick

- aggravation rate from phase B for latent sick - latent sick (LD)

- specific death rate for non-attendent sick - morbidity rate

RAGEt(1,J) registered sick aging rate REARt(1,J) - admission rate (REAR)

RECOVt(1) - recovery rate

REG(J) registered sick in phase J REGS

REMR(1) RSt(1,J) RW(1) SDR (I)

- all registered sick - remission rate

- registered sick - recovery weights - specific death rate

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-11-

General Part Variables ADMPt(J)

ALSCR(J) ASPRt DSPR HPt(I) HPSt LEV(J)

LSSt

NDRt(I,J) NDRD (I, J) PCTDt(J) REARt(J) RSt(I,J) RSSt(J) SCREP

t

- admission possibility

- probability not to detect a sick in screening - automated screening productivity

- doctor's screening productivity - healthy population in strata - healthy population summed

- level for the delay in doctors' requirement adjustment - latent sick (detailed)

latent sick fraction in non-registered population (to be screened)

- latent sick summed

- natural treatment demand rate

- natural treatment demand rate density - patients that can be treated by doctors - real admission rate

- registered sick (detailed) - registered sick in phases - screening productivity

SDOCt - number of screening doctors

SDSt(I,J) - rate of sick detected by screening

TDOCt TDPHt(J) TDPHDt(J) TDRt(I,J) TDRL

fraction of doctor's activities in screening standard workload for a doctor (i.e. patients in phase J per doctor)

- number of treatment doctors

- treatment doctors in a phase of a disease

density of treatment doctors in a phase of a disease - treatment demand rate (detailed)

- time lag in doctors' requirement

(14)

TDRSt(J) TOTDOC

t TFRAC

t

- treatment demand rate in phases - total doctors in practice

fraction of doctors' activities in treatment

(15)

-lJ-

Appendix 2

I signifies a sex-age structure;

J - a phase of the disease: A, B or C.

Natural Treatment Demand Rate

NDR(I,J)

=

NDRD(I,J) • LS(I,J)

NDRD is the fraction of LS in phase J that seek treatment on their own initiative.

Sick Detected by Screening

SDS{I,J)

=

SCREP • LS(I,J)/(LATS + HPS) • ALSCR(J)

Here

SCREP is screening productivity;

SCREP

=

ASPR + DSPR • SDOC

ASPR is automated screening productivity;

DSPR is the screening productivity of a physician;

SDOC is the number of doctors in screening;

SDOC

=

TOT DOC • SFRAC

TOTDOC are all the doctors in practice;

SFRAC is the fraction of doctor's activities in screening;

LATS are all the LS: LATS

= I .I

LS(I,J)

J I

HPS are all the HP: HP

= I

HP(I)

I

ALSCR(J) is probability to identify a Phase J LS in screening.

(16)

Admission Demand Rate

TDR(I,J)

=

NDR(I,J) + SDS(I,J)

Admission Demand Rate in Phases

TDRS(J)

= L

TDR(I,J)

I

Patients that can be Treated by Doctors

PCTD(J) = SWL(J) • TDPH(J)

Here

SWL(J) is the number of Phase J sick that can be treated by a doctor regularly, i.e. standard workload of a doctor;

TDPH(J) is the distribution of health care resources (doctors) in phases of the disease, TDPH(J) should be proportional to the RS in phase (J):

TDPH(J) should

=

PEG(J)/REGS • TDOC REG(J)

= L

RS(I,J)

I

REGS

= L L

RS(I,J)

J I

In practice, this equality is presumed to hold with delay:

TDRL is the lag time;

TDOC are the doctors (health care resources) in treatment:

TDOC

=

TOTDOC • TFRAC

TFRAC is the fraction of a doctor's activities in treatment.

Admission Possibility

ADMP(J)

=

PCTD(J) - REG(J)

(17)

-15-

Real Admission Rate

TDRS(J) REAR(J)

=

ADMP(J)

o

The Prevalence Equations

if ADMP(J) > 0, ADHP(J) ~ TDRS(J) if ADMP(J) > 0, ADMP(J) < TDRS(J) if ADMP(J) ::; 0

~cC;; '.'.

=

t< .•' (S ) ;r'';;;: (~))

j.;'EC('\i ::~ .; (~,) ..:JS (:~ • 11

.... f- ,.J.S:.;.Jti ": r s]*~~ U,2)

~0\.I; I ':~::{J ..~. ( ~ ) ;"" '" ( '" • 1 :)

~, ~r;i~k

=

:~

.,

P (~:.) ..p ;~\. ;~ , ;;»

L "l:. t,f, :" ::I..,<It 0;:' l ) ) •t.~ (~ , 1 )

LI" lJi;!.i~ ~I, ~,~&. :;' U J ...L ;) (::, ,? )

c c c c

HP ( S ) ::...,r' (S,) +11T .. ( .,'~ ('li1/.,I.t;,~, f~.. '.iioi

*

1-1P ( S ) +Hr,!;f. (

s ) )

TF-' rt-'t:' r

"n •

LT. i:;. i H;.1 (~) : r •

RS(5,1)=~~r5,1'+)T~(~tMJ~-4~GG~-D~.HS(5,1)"RECUV+

& Pti;F(5")+;:,;r,,,'f(~··,11J

c:

R 5 (~, ;: ) == [';~ ( ;; , ? )+i \T • ( Lll';; (,~- A ..C~U~-Ill-; ..i",S ( :-, , ?) ..1'1'E:;Ml ~+

~ 10~L.i;

r

3 , ,; )+

r,

t to:,: (~i ,~) ) C

QSi ;." ~.1 :"'<:-i

r

~l !J) + 'IT:* (~~ 4I~,;f,": ..S :_'q \~J

'*

P::- (5 , .~)+

& io' " G

r: (

5 • !- )+;J!';.,0 ;i (~, .3) , C

l S (~, 1. ) ::LJ (c:; , 1 ) .•r'1 p (1". ,;h:r< ..!.t,At;\Jr~LHH I S (~,, 1 )+

& LI~.f.:f. (i'; , 1 ) ..l~..~to:. f ;, •1 ) )

C

L 5 (~.~,? ) ::!.~ (~ ,2 ).~.)1

*

ll.•AII (:;!~1:, ..l.k ;.,.r; \:;~..j'\«

*

L~" ( S , 2 )+

3. I. t;(~t (0:; , ? )_.~r IIr" ( (; ,I'!) J

C C

L S (., ,:3 ) ;;L~ ( S •.~) • I)" '" t ,_c:I)f. (. '" ..L:~'J;":(&) .. '-5 ( :, , 3)+ It L'::Gr~

('".n- ....

r~I'f;~(.<,.~q)

C r.:

I)':!S .( ;.' j',:1 , 3

r';(R:i(~,'1)

.L.'

····~1 ~;:(.s,t)=~I.

j":ft;'CS,-.-:.) .~1. ;'.• } V,(.-:-,~)1:<il.

332 CONTINUE

(18)

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(19)

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(20)

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(21)

FIGURE:DemandforAdmission

--_ .... -._.-

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