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Supplementary Text 1

Our validation against Yin et al.’s data discovered the same (or very similar) non-canonical motifs for 42 of the 47 non-canonical motifs that we found in Yang et al.’s data (Yang et al.

2017). We show the results and comparisons in Supplementary Table 1. Of the 42 motifs, we found four cases with a single base change in the consensus sequence of the non-canonical motif, one case of two base changes in the consensus sequence, and three cases of a long overlap (5 of 8 bases) in the consensus sequence. The remaining 34 cases were the same.

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