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Pediatric Nephrology

Journal of the

International Pediatric Nephrology Association

Graphical Abstract

ACUTE KIDNEY INJURY IN CHILDREN HOSPITALIZED FOR COMMUNITY ACQUIRED PNEUMONIA

HYPOTHESIS: AKI prevalence could be under-recognized in children hospitalized for community acquired pneumonia DESIGN & OUTCOMES:

Marzuillo et al. 2021

CONCLUSION: About 20% of patients hospitalized for community acquired pneumonia have mostly mild AKI with longer stay for those with more

severe AKI. Main prognostic factors for AKI are duration of symptoms before hospitalization, severity of pneumonia and serum CRP levels.

186 children with community acquired

pneumonia

Retrospective single centre study

AKI prevalence

Independent predictors for AKI

AKI 20,4%

No AKI 79.6%

AKI Stage 0

20 40 60 80 100

13.2%

86.8%

1 2

Duration of symptoms before hospitalization:

OR=11.9;95%CI=4.30-33.30;p<0.001

Serum C-reactive protein levels:

OR=1.2;95%CI=1.09-1.43;p=0.001

Severe Pneumonia:

OR=1.1;95%CI=1.04-1.23;p=0.004

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