Supplemental Table 2
Association between maternal illness and Youth Self-Report scores of male cohort members in the Northern Finland Birth Cohort 1986
Assessment Parental somatic illness occurring between ages 8 and 16 years of cohort members
Maternal illness
Yes No
n YSR
mean (SD)
n YSR
mean (SD) p- value
Cohen’s d
p- valuea
p- valueb
B-Hpc
YSR tot Certain infectious and parasitic diseases 37 23.2 (15.7) 3345 21.8 (13.8) 0.541 0.608 0.697
Neoplasms 158 22.3 (13.2) 3224 21.8 (13.8) 0.648 0.650 0.543
Endocrine, nutritional and metabolic diseases 36 17.1 (9.5) 3346 21.9 (13.8) 0.005 -0.35 0.032 0.019 0.04 Diseases of the blood and blood-forming
organs and certain disorders involving the immune mechanism
11 22.1 (15.2) 3371 21.9 (13.8) 0.955 0.858 0.945
Mental and behavioral disorders 59 26.6 (16.7) 3323 21.8 (13.7) 0.008 0.35 0.007 0.005 0.032
Diseases of the nervous system 162 21.0 (14.5) 3220 21.9 (13.8) 0.445 0.579 0.318
Diseases of the circulatory system 525 21.6 (14.0) 2857 21.9 (13.8) 0.711 0.928 0.924
Diseases of the respiratory system 127 19.5 (9.7) 3255 21.9 (13.9) 0.007 -0.17 0.069 0.025 0.037
Diseases of the digestive system 154 21.1 (13.4) 3228 21.9 (13.8) 0.481 0.401 0.399
Diseases of the genitourinary system 330 21.8 (14.1) 3052 21.9 (13.8) 0.923 0.985 0.921 Diseases of the skin and subcutaneous tissue 27 26.0 (17.8) 3355 21.8 (13.8) 0.116 0.122 0.157
Diseases of the musculoskeletal system and connective tissue
293 23.4 (13.8) 3089 21.7 (13.8) 0.040 0.12 0.031 0.068 0.107
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
191 22.6 (14.0) 3191 21.8 (13.8) 0.443 0.389 0.396
Injury, poisoning and certain other consequences of external causes
137 24.4 (15.4) 3245 21.7 (13.7) 0.029 0.20 0.018 0.040 0.093
External causes of morbidity and mortality 65 18.2 (9.1) 3317 21.9 (13.9) 0.002 -0.27 0.043 0.047 0.032 Factors influencing health status and contact
with health services
383 21.4 (13.7) 2999 21.9 (13.8) 0.539 0.725 0.531
YSR int Certain infectious and parasitic diseases 37 6.3 (5.6) 3338 6.4 (5.3) 0.885 0.887 0.809
Neoplasms 158 6.3 (4.8) 3217 6.4 (5.3) 0.857 0.834 0.793
Endocrine, nutritional and metabolic diseases 36 5.2 (4.1) 3339 6.4 (5.3) 0.165 0.154 0.067 Diseases of the blood and blood-forming
organs and certain disorders involving the immune mechanism
11 7.1 (6.1) 3364 6.4 (5.3) 0.661 0.620 0.740
Mental and behavioral disorders 59 8.1 (7.1) 3316 6.4 (5.3) 0.059 0.32 0.011 0.003 0.315
Diseases of the nervous system 160 6.3 (4.7) 3215 6.4 (5.3) 0.905 0.973 0.582
Diseases of the circulatory system 524 6.5 (5.1) 2851 6.4 (5.3) 0.525 0.266 0.424
Diseases of the respiratory system 127 5.5 (4.0) 3248 6.4 (5.3) 0.015 -0.17 0.079 0.022 0.24
Diseases of the digestive system 153 6.0 (4.6) 3222 6.4 (5.3) 0.327 0.307 0.236
Diseases of the genitourinary system 329 6.4 (5.4) 3046 6.4 (5.3) 0.897 0.855 0.857
Diseases of the skin and subcutaneous tissue 27 7.9 (5.8) 3348 6.4 (5.3) 0.135 0.143 0.186
Diseases of the musculoskeletal system and connective tissue
290 6.7 (5.1) 3085 6.3 (5.3) 0.248 0.318 0.536
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
191 6.6 (5.4) 3184 6.4 (5.3) 0.548 0.515 0.720
Injury, poisoning and certain other consequences of external causes
137 7.1 (5.9) 3238 6.4 (5.3) 0.091 0.074 0.159
External causes of morbidity and mortality 65 5.4 (4.1) 3310 6.4 (5.3) 0.051 0.128 0.124 0.408 Factors influencing health status and contact
with health services
383 6.3 (5.2) 2992 6.4 (5.3) 0.614 0.562 0.442
YSR ext Certain infectious and parasitic diseases 36 10.0 (5.7 ) 3323 9.0 (6.2) 0.370 0.532 0.814
Neoplasms 158 9.2 (5.5) 3201 9.0 (6.2) 0.747 0.762 0.592
Endocrine, nutritional and metabolic diseases 36 6.9 (4.5) 3323 9.1 (6.2) 0.037 -0.36 0.029 0.032 0.118 Diseases of the blood and blood-forming
organs and certain disorders involving the immune mechanism
11 8.0 (5.1) 3348 9.0 (6.2) 0.576 0.858 0.506
Mental and behavioral disorders 59 10.7 (7.1) 3300 9.0 (6.1) 0.036 0.28 0.035 0.027 0.144
Diseases of the nervous system 158 9.0 (6.6) 3201 9.0 (6.1) 0.880 0.960 0.754
Diseases of the circulatory system 522 8.8 (6.5) 2837 9.1 (6.1) 0.439 0.648 0.662
Diseases of the respiratory system 127 8.4 (4.7) 3232 9.1 (6.2) 0.116 0.240 0.114
Diseases of the digestive system 152 9.3 (6.6) 3207 9.0 (6.1) 0.597 0.738 0.688
Diseases of the genitourinary system 326 9.2 (6.5) 3033 9.0 (6.1) 0.714 0.651 0.780
Diseases of the skin and subcutaneous tissue 27 9.7 (7.6) 3332 9.0 (6.2) 0.555 0.583 0.683
Diseases of the musculoskeletal system and connective tissue
289 9.8 (6.3) 3070 9.0 (6.2) 0.033 0.13 0.017 0.024 0.176
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
191 9.1 (6.0) 3168 9.0 (6.2) 0.843 0.788 0.641
Injury, poisoning and certain other consequences of external causes
136 10.2 (6.8) 3223 9.0 (6.1) 0.031 0.20 0.018 0.037 0.248
External causes of morbidity and mortality 65 7.6 (4.4) 3294 9.1 (6.2) 0.011 -0.25 0.072 0.080 0.176 Factors influencing health status and contact
with health services
379 9.2 (6.1) 2980 9.0 (6.2) 0.681 0.427 0.609
Abbreviation: SD, standard deviation; YSR, Youth Self-Report; tot, total scores; int, internalizing scores; ext, externalizing scores a Adjusted for the score of Rutter Children’s Behavior Questionnaire scale B2
b Adjusted for all adjusting factors: socioeconomic status of either parent, score of Rutter Children’s Behavior Questionnaire scale B2, parental psychiatric diagnoses c Benjamini-Hochberg corrected p-value