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Bibliographie 1. Kunkel, T. A. Celebrating DNA’s Repair Crew. Cell 163, 1301–3 (2015). 2. Abegglen, L. M. et al. Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA 314, 1850–60 (

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Bibliographie

1. Kunkel, T. A. Celebrating DNA’s Repair Crew. Cell 163, 1301–3 (2015).

2. Abegglen, L. M. et al. Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA 314, 1850–60 (2015).

3. Krug, N. et al. Allergen-induced asthmatic responses modified by a GATA3- specific DNAzyme. N. Engl. J. Med. 372, 1987–95 (2015).

4. Bel, E. H. et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N. Engl. J. Med. 371, 1189–97 (2014).

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7. Brahmer, J. et al. Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer. N. Engl. J. Med. 373, 123–35 (2015).

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16. Robinson, J. G. et al. Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. N. Engl. J. Med. 372, 1489–99 (2015).

17. Clark, N. P. et al. Bleeding, Recurrent Venous Thromboembolism, and Mortality Risks During Warfarin Interruption for Invasive Procedures. JAMA Intern. Med. 175, 1163–8 (2015).

18. Douketis, J. D. et al. Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation. N. Engl. J. Med. 373, 823–33 (2015).

19. Feldman, T. et al. Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation. J. Am. Coll. Cardiol. 66, 2844–2854 (2015).

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21. Reynolds, D. et al. A Leadless Intracardiac Transcatheter Pacing System. N.

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Replacement in Patients With Severe Aortic Valve Stenosis: 1-Year Results From the All-Comers NOTION Randomized Clinical Trial. J. Am. Coll. Cardiol. 65, 2184–94 (2015).

24. Langley, R. G. et al. Secukinumab in plaque psoriasis--results of two phase 3 trials. N. Engl. J. Med. 371, 326–38 (2014).

25. Thaçi, D. et al. Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial. J. Am. Acad. Dermatol. 73, 400–9 (2015).

26. Mease, P. J. et al. Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis. N. Engl. J. Med. 373, 1329–39 (2015).

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mechanisms, metabolic effects and implications for the treatment of diabetic patients with chronic kidney disease. Nephrol. Dial. Transplant 30, 1272–6 (2015).

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35. Williams, B. et al. Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY- 2): a randomised, double-blind, crossover trial. Lancet (London, England) 386, 2059–68 (2015).

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