Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release

In this lecture, the focus will be on quality control of protein folding and how microscopic analysis has been instrumental in dissecting its subcellular topography

After 3 months treatment with E2, GEN, gene expression of IGF-1 in the left ventricle of estrogen receptor alpha knockout mice (αERKO) is not altered by E2 and GEN compared with

The studies  of  recombinant  GABA B   receptors  displayed  different  receptor  characteristics  compared  to  native  GABA B   receptors.  Affinity‐purification  of 

The C-terminal domain of the GABA B1 subunit harbours an arginine-based ER retention/retrieval signal, RSRR, which retains unassembled GABA B1 subunits in the ER and

It could be demonstrated that postsynaptic GABA B receptors colocalize with the Kir3.2 subunit of K + - channels in dendritic spines, but not in dendritic shafts of CA1

selective GABA B receptor ligands were tested in the presence and the absence of positive allosteric modulators CGP7930 and GS39783 in in vitro assays, such as radioligand binding,

The aim of this thesis was therefore to determine the contribution of the GABA B(1) receptor isoforms to endophenotypes of depression and anxiety- related disorders, by

Alternatively spliced cytokine receptor variants are emerging as regulators of cytokine signaling 36-38,68,109,110. The c-mpl locus gives rise to the full-length mpl protein