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Antibacterial Activity and Chemical Composition of the Essential Oil of Grammosciadium platycarpum Boiss. from Iran

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Antibacterial Activity and Chemical Composition of the Essential Oil of Grammosciadium platycarpum Boiss. from Iran

Ali Sonboli

a,*

, Fereshteh Eftekhar

b

, Morteza Yousefzadi

b

, and Mohammad Reza Kanani

a

a Department of Biology, Medicinal Plants Research Institute, Shahid Beheshti University, Evin, P.O. Box 19835-389, Tehran, Iran. Fax: (+98 21)2 41 86 79. E-mail: a-sonboli@sbu.ac.ir

b Department of Biology, Faculty of Sciences, Shahid Beheshti University, Evin, Tehran, Iran

* Author for correspondence and reprint requests

Z. Naturforsch.60 c, 30Ð34 (2005); received September 17/November 23, 2004

The chemical composition of the essential oils obtained from two samples (GP1 and GP2) ofGrammosciadium platycarpumBoiss. was analyzed by GC and GC-MS. The analysis of the oils resulted in the identification of twenty-two constituents. Linalool (79.0% Ð GP1, 81.8%ÐGP2) and limonene (10.0%, 5.8%) were found to be the major components, respec- tively. The in vitro antibacterial activities of these oils and their main compounds against seven Gram-positive and Gram-negative bacteria were investigated. The results exhibited that the total oils and their major components possess strong to moderate activities against all the tested bacteria except forPseudomonas aeruginosa.

Key words: Grammosciadium, Essential Oil, Antibacterial Activity

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