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FOXP2 -The “Language Gene“-

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(1)

FOXP2

-The “Language Gene“-

Presentation by Melanie Selle

&

Hüseyin Balim

(2)

Outline

Introduction

Discovery

KE-family

Pedigree of the KE family

Description of F0XP2

Function

FOXP2 in humanbeings

Developmental dyspraxia

FOXP2 in animals

Songbirds

Evolution Aspect and Scientific Background

Scientists find gene 'switch' linked to speech The importance of being human *

Mice Given 'Human' Version of Speech Gene*

Conclusion

References

(3)

Central Questions

Why can just a single gene have such a huge impact on our language ability?

What really differs animal from human communication?

(4)

Discovery

1990 discovered by Myrna Gopnik

During research on the KE family

(5)

KE family

Affected family members exhibit specific language impairment

Disorder is associated with a mutation in a single

autosomal-dominant gene

(6)

Pedigree of the KE family

(7)

Where is the FOXP2 gene located?

• Correlation of sets of small stretches of

DNA between affected and not-

affected members of the KE family

Variations in the small locus of the long arm of chromosome 7

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